'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease

Cell Death and Differentiation

Volumn 9, Issue 9, 2002, Pages 873-880

  Mastroberardino, P G ^a   Iannicola, C ^a   Nardacci, R ^b   Bernassola, F ^a   De Laurenzi, V ^a   Melino, G ^a   Moreno, S ^d   Pavone, F ^e   Oliverio, S ^a   Fesus, L ^c   Piacentini, M ^a,b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^c UNIVERSITY OF DEBRECEN   (Hungary)

^d ROMA TRE UNIVERSITY   (Italy)

^e CNR   (Italy)

Author keywords

Autophagy; Huntingtin; Neurodegeneration; Nuclear inclusions; ( glutamyl)lysine crosslinks

Indexed keywords

PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL NUCLEUS INCLUSION BODY; CELL SURVIVAL; CONTROLLED STUDY; CROSSING OVER; DISEASE MODEL; ENZYME ACTIVITY; ENZYME REGULATION; HUNTINGTON CHOREA; IN VIVO STUDY; KNOCKOUT MOUSE; MOTOR PERFORMANCE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; BRAIN; CELL DEATH; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; GTP-BINDING PROTEINS; GUANOSINE TRIPHOSPHATE; HUNTINGTON DISEASE; IMMUNOHISTOCHEMISTRY; INCLUSION BODIES; LONGEVITY; MALE; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; MOTOR ACTIVITY; NEOCORTEX; NEOSTRIATUM; NERVE DEGENERATION; NERVE TISSUE PROTEINS; NEURONS; SURVIVAL RATE; TRANSGLUTAMINASES;

ANIMALIA; MUS MUSCULUS;

EID: 0036715380     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401093     Document Type: Article

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