Double-check probing of DNA bending and unwinding by XPA-RPA: An architectural function in DNA repair

EMBO Journal

Volumn 20, Issue 13, 2001, Pages 3554-3564

  Missura, Miriam ^a   Buterin, Tonko ^a   Hindges, Robert ^a   Hübscher, Ulrich ^a   Kaspárková, Jana ^b   Brabec, Viktor ^b   Naegeli, Hanspeter ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b INSTITUTE OF BIOPHYSICS   (Czech Republic)

Author keywords

Damage recognition; DNA repair; Xeroderma pigmentosum; XPA RPA

Indexed keywords

CURVED DNA; PROTEIN; PROTEIN XPA; REPLICATION PROTEIN A; UNCLASSIFIED DRUG;

ARTICLE; BASE MISPAIRING; DNA ADDUCT; DNA CONFORMATION; DNA DENATURATION; DNA HELIX; DNA REPAIR; EXCISION REPAIR; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; XERODERMA PIGMENTOSUM;

BASE PAIR MISMATCH; BASE SEQUENCE; BINDING SITES; DNA; DNA HELICASES; DNA REPAIR; DNA-BINDING PROTEINS; ESCHERICHIA COLI; HUMANS; HYDROGEN BONDING; KINETICS; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; OLIGODEOXYRIBONUCLEOTIDES; RECOMBINANT PROTEINS; REPLICATION PROTEIN A; RNA-BINDING PROTEINS; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

EID: 0035796455     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.13.3554     Document Type: Article

References (45)

1. Mammalian DNA nucleotide excision repair reconstituted with purified components
2. Nucleotide excision repair of DNA with recombinant human proteins: Definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK
3. The XPA protein is a zinc metalloprotein with an ability to recognize various kinds of DNA damage
4. Stable binding of human XPC complex to irradiated DNA confers strong discrimination for damaged sites
5. An affinity of human replication protein A for ultraviolet-damaged DNA
6. Nucleotide excision repair and human syndromes
7. DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair
8. Mechanism of open complex and dual incision formation by human nucleotide excision repair factors
9. Characterization of DNA recognition by the human UV-damaged DNA-binding protein
10. DNA unwinding activity of replication protein A
11. Ribosome-catalyzed peptide-bond formation with an A-site substrate covalently linked to 23S ribosomal RNA
12. RPA involvement in the damage-recognition and incision steps of nucleotide excision repair
13. Recombinant replication protein A: Expression, purification, and functional characterization
14. Bipartite substrate discrimination by human nucleotide excision repair
15. Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes
16. Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5′ and the 6th phosphodiester bond 3′ to the photodimer
17. Structure of an adenine cytosine base pair in DNA and its implications for mismatch repair
18. Solution structure of the DNA-and RPA-binding domain of the human repair factor XPA
19. Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA
20. Site-specific d(GpG) intrastrand crosslinks formed by dinuclear platinum complexes. Bending and NMR studies
21. Functional complementation of xeroderma pigmentosum group E by replication protein A in an in vitro system
22. Mutational analysis of a function of xeroderma pigmentosum group A (XPA) protein in strand-specific repair
23. Replication protein A interactions with DNA. III. Molecular basis of recognition of damaged DNA
24. An interaction between the DNA repair factor XPA and replication protein A appears essential for nucleotide excision repair
25. 3-Nitropyrrole and 5-nitroindole as universal bases in primers for DNA sequencing and PCR
26. Human DNA repair excision nuclease
27. Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA
28. Reconstitution of human DNA repair excision nuclease in a highly defined system
29. Reaction mechanism of human DNA repair excision nuclease
30. Characterization of reaction intermediates of human excision repair nuclease
31. Crystal structure of a DNA Holliday junction
32. DNA excision repair
33. An electron microscopic study of (A)BC excinuclease
34. Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair
35. Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin
36. Xeroderma pigmentosum p48 gene enhances genomic repair and suppresses UV-induced mutagenesis
37. Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes
38. Architecture of nucleotide excision repair complexes: DNA is wrapped by UvrB before and after damage recognition
39. Assembly, subunit composition, and footprint of human DNA repair excision nuclease
40. Order of assembly of human DNA repair excision nuclease
41. Replication protein A
42. DNA repair in eukaryotes
43. The xeroderma pigmentosum group C protein complex XPC-HR23B plays an important role in the recruitment of transcription factor IIH to damaged DNA
44. Binding to four-way junction DNA: A common property of architectural proteins