Proteome-wide reactivity profiling identifies diverse carbamate chemotypes tuned for serine hydrolase inhibition

ACS Chemical Biology

Volumn 8, Issue 7, 2013, Pages 1590-1599

  Chang, Jae Won ^a   Cognetta, Armand B ^a   Niphakis, Micah J ^a   Cravatt, Benjamin F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLGLYCEROL LIPASE; ALPHA BETA HYDROLASE 6; CARBAMIC ACID; CARBAMIC ACID DERIVATIVE; ENDOCANNABINOID; HYDROLASE; O ARYL CARBAMATE; O HEXAFLUOROISOPROPYL CARBAMATE; O N HYDROXYSUCCINIMIDYL CARBAMATE; PROTEOME; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CLICK CHEMISTRY; CONTROLLED STUDY; ENZYME INHIBITION; IMAGING; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BRAIN; CARBAMATES; CELL LINE, TUMOR; CLICK CHEMISTRY; MICE; MICROSCOPY, FLUORESCENCE; MOLECULAR STRUCTURE; PROTEIN ARRAY ANALYSIS; PROTEOME; SERINE PROTEASES; SERINE PROTEINASE INHIBITORS;

EID: 84880517778     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400261h     Document Type: Article

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