Multitargeted inhibition of hepatic fibrosis in chronic iron-overloaded mice by Salvia miltiorrhiza

Journal of Ethnopharmacology

Volumn 148, Issue 2, 2013, Pages 671-681

  Zhang, Ying ^a   Zhang, Yuanyuan ^a   Xie, Yun ^a   Gao, Yonggang ^a   Ma, Juanjuan ^a   Yuan, Jie ^a   Li, Juan ^a   Wang, Jiangyan ^b   Li, Lei ^a   Zhang, Jianping ^a   Chu, Li ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Bethune Military Medical College   (China)

Author keywords

Iron overload Salvia miltiorrhiza Multitarget Hepatic fibrosis

Indexed keywords

COLLAGEN TYPE 3; GELATINASE B; GLUTATHIONE; HYDROXYPROLINE; INTERLEUKIN 1ALPHA; IRON; IRON DEXTRAN; MALONALDEHYDE; MESSENGER RNA; SALVIA MILTIORRHIZA EXTRACT; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; IRON OVERLOAD; LIVER FIBROSIS; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALVIA MILTIORRHIZA;

ANIMALS; COLLAGEN TYPE I; COLLAGEN TYPE III; DOWN-REGULATION; HYDROXYPROLINE; INTERLEUKIN-1ALPHA; IRON OVERLOAD; LIVER; LIVER CIRRHOSIS; MALE; MICE; OXIDATIVE STRESS; PLANT EXTRACTS; RANDOM ALLOCATION; SALVIA MILTIORRHIZA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

MUS; SALVIA MILTIORRHIZA;

EID: 84879417064     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.05.028     Document Type: Article

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