Accelerated hepatic fibrosis in patients with combined hereditary hemochromatosis and chronic hepatitis C infection

Journal of Hepatology

Volumn 36, Issue 5, 2002, Pages 687-691

  Diwakaran, Hari H ^a   Befeler, Alex S ^a   Britton, Robert S ^a   Brunt, Elizabeth M ^a   Bacon, Bruce R ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fibrosis; Hemochromatosis; Hepatitis C; HFE; Iron; Liver

Indexed keywords

FERRITIN; TRANSFERRIN;

ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROGENESIS; GENE MUTATION; GENOTYPE; HEMOCHROMATOSIS; HEPATITIS C; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; IRON OVERLOAD; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FIBROSIS; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADULT; AGE OF ONSET; ALANINE TRANSAMINASE; FERRITINS; HEMOCHROMATOSIS; HEPATITIS C; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; TRANSFERRIN;

EID: 0036258015     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(02)00018-1     Document Type: Article

References (34)

1. Molecular medicine and hemochromatosis: At the crossroads
2. The prevalence of hepatitis C virus in the United States, 1988-1994
3. Is there a threshold of hepatic iron concentration that leads to cirrhosis in C282Y hemochromatosis?
4. Measurements of iron status in patients with chronic hepatitis
5. Iron in liver diseases other than hemochromatosis
6. Hepatitis C and iron
7. Determination of hepatic iron concentration in fresh and paraffin-embedded tissue: Diagnostic implications
8. Liver damage in Italian patients with hereditary hemochromatosis is highly influenced by hepatitis B and C virus infection
9. Lipid peroxidation and iron associated organelle dysfunction in iron overload
10. Hepatic injury in chronic iron overload: Role of lipid peroxidation
11. Metal-induced hepatotoxicity
12. Histological evaluation of iron in liver biopsies: Relationship to HFE mutations
13. Iron and chronic viral hepatitis
14. Iron reduction therapy: Simply camouflage, or a real weapon?
15. A pilot randomized, controlled trial of the effect of iron depletion on long term response to alpha interferon in patients with chronic hepatitis C
16. Iron reduction before and during interferon therapy of chronic hepatitis C: Results of a multicenter, randomized, controlled trial
17. Iron reduction as an adjuvant to interferon therapy in patients with chronic hepatitis C who have not previously responded to interferon: A multicenter, prospective, randomized, controlled trial
18. Response to interferon alpha therapy is influenced by the iron content of the liver
19. Iron stores, response to alpha interferon therapy, and effects of iron depletion in chronic hepatitis C
20. Liver iron influences the response to interferon alpha therapy in chronic hepatitis C
21. Failure to respond to interferon-alpha 2a therapy is associated with increased hepatic iron levels in patients with chronic hepatitis C
22. Improvement of serum aminotransferase level after phlebotomy in patients with chronic active hepatitis C and excess hepatic iron
23. Hemochromatosis: Diagnosis and management
24. Heterozygosity for hereditary hemochromatosis is associated with more fibrosis in chronic hepatitis C
25. Threshold effect of liver iron content on hepatic inflammation and fibrosis in hepatitis B and C
26. Are hemochromatosis mutations related to the severity of liver disease in hepatitis C virus infection?
27. Hemochromatosis gene mutations in chronic hepatitis C patients with and without liver siderosis
28. Role of HFE gene mutations in liver diseases other than hereditary hemochromatosis
29. Iron and liver diseases
30. Hepatic iron overload in patients with chronic viral hepatitis. Role of HFE gene mutations
31. Liver iron accumulation in patients with chronic hepatitis C: Prevalence and role of hemochromatosis gene mutations and relationship with hepatic histological lesions
32. The relation of iron status and hemochromatosis gene mutations in patients with chronic hepatitis C
33. C282Y mutation and hepatic iron status in hepatitis C and cryptogenic cirrhosis