Mechanisms of Nrf2/keap1-dependent phase II cytoprotective and detoxifying gene expression and potential cellular targets of chemopreventive isothiocyanates

Oxidative Medicine and Cellular Longevity

Volumn , Issue , 2013, Pages

  Das, Biswa Nath ^a   Kim, Young Woo ^a   Keum, Young Sam ^a  

^a Dongguk University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOPREVENTIVE EFFECTS; CRUCIFEROUS VEGETABLES; DETOXIFYING ENZYMES; EPIDEMIOLOGICAL STUDIES; INTRACELLULAR SIGNALING; NUCLEOCYTOPLASMIC TRAFFICKING; POST-TRANSLATIONAL MODIFICATIONS; REACTIVE OXYGEN SPECIES;

CHEMICAL COMPOUNDS; ENZYMES; VEGETABLES;

GENE EXPRESSION;

ISOTHIOCYANIC ACID DERIVATIVE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C JUN; PROTEIN KINASE C; STAT3 PROTEIN; ISOTHIOCYANIC ACID; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR NRF2;

CELL PROTECTION; CHEMOPROPHYLAXIS; GENE EXPRESSION; HUMAN; MODULATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; POINT MUTATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REVIEW; TRANSACTIVATION; ANIMAL; DRUG DETOXIFICATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; CHEMOPREVENTION; CYTOPROTECTION; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOTHIOCYANATES; METABOLIC DETOXICATION, PHASE II; NF-E2-RELATED FACTOR 2;

EID: 84879403678     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2013/839409     Document Type: Review

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