Proteomic identification of binding targets of isothiocyanates: A perspective on techniques

Journal of Proteomics

Volumn 74, Issue 7, 2011, Pages 1036-1044

  Mi, Lixin ^a   Xiao, Zhen ^b   Veenstra, Timothy D ^b   Chung, Fung Lung ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

Covalent modification; Isothiocyanates; Mass spectrometry; Proteomics; Target identification

Indexed keywords

ANTINEOPLASTIC AGENT; CELL PROTEIN; ISOTHIOCYANIC ACID DERIVATIVE; TUBULIN;

AFFINITY CHROMATOGRAPHY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; DRUG BINDING; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG TARGETING; HUMAN; ISOTOPE LABELING; MASS SPECTROMETRY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN TARGETING; PROTEOMICS; REVIEW; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANTICARCINOGENIC AGENTS; BINDING SITES; CHROMATOGRAPHY, AFFINITY; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ISOTHIOCYANATES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEOMICS; TANDEM MASS SPECTROMETRY; TUBULIN;

EID: 79957653767     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2011.04.015     Document Type: Review

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