-
1
-
-
49349107361
-
-
[internet], (accessed January 2, 2013)
-
WHO. The top 10 causes of death [internet]. Available from: http:// www.who.int/mediacentre/factsheets/fs310/en/index.html (accessed January 2, 2013).
-
The Top 10 Causes of Death
-
-
-
3
-
-
0017402583
-
The natural history of chronic airflow obstruction
-
Fletcher C, Peto R. The natural history of chronic airflow obstruction. BMJ 1977;1: 1645-1648.
-
(1977)
BMJ
, vol.1
, pp. 1645-1648
-
-
Fletcher, C.1
Peto, R.2
-
4
-
-
0345701470
-
Not 15 but 50% of smokers develop COPD? Report from the Obstructive Lung Disease in Northern Sweden Studies
-
Obstructive Lung Disease in Northern Sweden Studies
-
Lundbäck B, Lindberg A, Lindström M, Rönmark E, Jonsson AC, Jönsson E, Larsson LG, Andersson S, Sandström T, Larsson K; Obstructive Lung Disease in Northern Sweden Studies. Not 15 but 50% of smokers develop COPD? Report from the Obstructive Lung Disease in Northern Sweden Studies. Respir Med 2003;97: 115-122.
-
(2003)
Respir Med
, vol.97
, pp. 115-122
-
-
Lundbäck, B.1
Lindberg, A.2
Lindström, M.3
Rönmark, E.4
Jonsson, A.C.5
Jönsson, E.6
Larsson, L.G.7
Andersson, S.8
Sandström, T.9
Larsson, K.10
-
5
-
-
80055014103
-
Pathogenic triad in COPD: Oxidative stress, protease-antiprotease imbalance, and inflammation
-
Fischer BM, Pavlisko E, Voynow JA. Pathogenic triad in COPD: oxidative stress, protease-antiprotease imbalance, and inflammation. Int J Chron Obstruct Pulmon Dis 2011;6: 413-421.
-
(2011)
Int J Chron Obstruct Pulmon Dis
, vol.6
, pp. 413-421
-
-
Fischer, B.M.1
Pavlisko, E.2
Voynow, J.A.3
-
7
-
-
0030997435
-
Granules of the human neutrophilic polymorphonuclear leukocyte
-
Borregaard N, Cowland JB. Granules of the human neutrophilic polymorphonuclear leukocyte. Blood 1997;89: 3503-3521.
-
(1997)
Blood
, vol.89
, pp. 3503-3521
-
-
Borregaard, N.1
Cowland, J.B.2
-
8
-
-
0021871257
-
Cigarette smoking causes accumulation of polymorphonuclear leukocytes in alveolar septum
-
Ludwig PW, Schwartz BA, Hoidal JR, Niewoehner DE. Cigarette smoking causes accumulation of polymorphonuclear leukocytes in alveolar septum. Am Rev Respir Dis 1985;131: 828-830.
-
(1985)
Am Rev Respir Dis
, vol.131
, pp. 828-830
-
-
Ludwig, P.W.1
Schwartz, B.A.2
Hoidal, J.R.3
Niewoehner, D.E.4
-
9
-
-
0021998466
-
The effects of chronic bronchitis and chronic air-flow obstruction on lung cell populations recovered by bronchoalveolar lavage
-
Martin TR, Raghu G, Maunder RJ, Springmeyer SC. The effects of chronic bronchitis and chronic air-flow obstruction on lung cell populations recovered by bronchoalveolar lavage. Am Rev Respir Dis 1985;132: 254-260.
-
(1985)
Am Rev Respir Dis
, vol.132
, pp. 254-260
-
-
Martin, T.R.1
Raghu, G.2
Maunder, R.J.3
Springmeyer, S.C.4
-
10
-
-
0031855525
-
Neutrophils infiltrating bronchial epithelium in chronic obstructive pulmonary disease
-
Pesci A, Majori M, Cuomo A, Borciani N, Bertacco S, Cacciani G, Gabrielli M. Neutrophils infiltrating bronchial epithelium in chronic obstructive pulmonary disease. Respir Med 1998;92: 863-870.
-
(1998)
Respir Med
, vol.92
, pp. 863-870
-
-
Pesci, A.1
Majori, M.2
Cuomo, A.3
Borciani, N.4
Bertacco, S.5
Cacciani, G.6
Gabrielli, M.7
-
11
-
-
34248231698
-
Increased galectin-3 expression and intra-epithelial neutrophils in small airways in severe COPD
-
Pilette C, Colinet B, Kiss R, André S, Kaltner H, Gabius HJ, Delos M, Vaerman JP, Decramer M, Sibille Y. Increased galectin-3 expression and intra-epithelial neutrophils in small airways in severe COPD. Eur Respir J 2007;29: 914-922.
-
(2007)
Eur Respir J
, vol.29
, pp. 914-922
-
-
Pilette, C.1
Colinet, B.2
Kiss, R.3
André, S.4
Kaltner, H.5
Gabius, H.J.6
Delos, M.7
Vaerman, J.P.8
Decramer, M.9
Sibille, Y.10
-
12
-
-
0029978437
-
Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils
-
Stǎnescu D, Sanna A, Veriter C, Kostianev S, Calcagni PG, Fabbri LM, Maestrelli P. Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils. Thorax 1996;51: 267-271.
-
(1996)
Thorax
, vol.51
, pp. 267-271
-
-
Stǎnescu, D.1
Sanna, A.2
Veriter, C.3
Kostianev, S.4
Calcagni, P.G.5
Fabbri, L.M.6
Maestrelli, P.7
-
13
-
-
6344267160
-
Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD
-
O'Donnell RA, Peebles C, Ward JA, Daraker A, Angco G, Broberg P, Pierrou S, Lund J, Holgate ST, Davies DE, et al. Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD. Thorax 2004;59: 837-842.
-
(2004)
Thorax
, vol.59
, pp. 837-842
-
-
O'donnell, R.A.1
Peebles, C.2
Ward, J.A.3
Daraker, A.4
Angco, G.5
Broberg, P.6
Pierrou, S.7
Lund, J.8
Holgate, S.T.9
Davies, D.E.10
-
14
-
-
0034883814
-
Changes in bronchial inflammation during acute exacerbations of chronic bronchitis
-
Gompertz S, O'Brien C, Bayley DL, Hill SL, Stockley RA. Changes in bronchial inflammation during acute exacerbations of chronic bronchitis. Eur Respir J 2001;17: 1112-1119.
-
(2001)
Eur Respir J
, vol.17
, pp. 1112-1119
-
-
Gompertz, S.1
O'brien, C.2
Bayley, D.L.3
Hill, S.L.4
Stockley, R.A.5
-
15
-
-
0037378123
-
Unique structural features that influence neutrophil emigration into the lung
-
Burns AR, Smith CW, Walker DC. Unique structural features that influence neutrophil emigration into the lung. Physiol Rev 2003;83: 309-336.
-
(2003)
Physiol Rev
, vol.83
, pp. 309-336
-
-
Burns, A.R.1
Smith, C.W.2
Walker, D.C.3
-
16
-
-
84861879876
-
Mechanisms of neutrophil transmigration across the vascular endothelium in COPD
-
Gane J, Stockley R. Mechanisms of neutrophil transmigration across the vascular endothelium in COPD. Thorax 2012;67: 553-561.
-
(2012)
Thorax
, vol.67
, pp. 553-561
-
-
Gane, J.1
Stockley, R.2
-
17
-
-
0024376371
-
Mechanics of stimulated neutrophils: Cell stiffening induces retention in capillaries
-
Worthen GS, Schwab B III, Elson EL, Downey GP. Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries. Science 1989;245: 183-186.
-
(1989)
Science
, vol.245
, pp. 183-186
-
-
Worthen, G.S.1
Schwab III, B.2
Elson, E.L.3
Downey, G.P.4
-
18
-
-
70949091447
-
The cytokine network in chronic obstructive pulmonary disease
-
Barnes PJ. The cytokine network in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2009;41: 631-638.
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 631-638
-
-
Barnes, P.J.1
-
19
-
-
33644828187
-
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
-
Weathington NM, et al. A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat Med 2006;12: 317-323.
-
(2006)
Nat Med
, vol.12
, pp. 317-323
-
-
Weathington, N.M.1
-
21
-
-
84859508650
-
Defective phagocytosis in airways disease
-
Donnelly LE, Barnes PJ. Defective phagocytosis in airways disease. Chest 2012;141: 1055-1062.
-
(2012)
Chest
, vol.141
, pp. 1055-1062
-
-
Donnelly, L.E.1
Barnes, P.J.2
-
22
-
-
0041346077
-
Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells
-
Hodge S, Hodge G, Scicchitano R, Reynolds PN, Holmes M. Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunol Cell Biol 2003;81: 289-296.
-
(2003)
Immunol Cell Biol
, vol.81
, pp. 289-296
-
-
Hodge, S.1
Hodge, G.2
Scicchitano, R.3
Reynolds, P.N.4
Holmes, M.5
-
23
-
-
66249127897
-
Cigarette smoke impairs clearance of apoptotic cells through oxidantdependent activation of RhoA
-
Richens TR, Linderman DJ, Horstmann SA, Lambert C, Xiao YQ, Keith RL, Boé DM, Morimoto K, Bowler RP, Day BJ, et al. Cigarette smoke impairs clearance of apoptotic cells through oxidantdependent activation of RhoA. Am J Respir Crit Care Med 2009; 179: 1011-1021.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 1011-1021
-
-
Richens, T.R.1
Linderman, D.J.2
Horstmann, S.A.3
Lambert, C.4
Xiao, Y.Q.5
Keith, R.L.6
Boé, D.M.7
Morimoto, K.8
Bowler, R.P.9
Day, B.J.10
-
24
-
-
70349758338
-
TNFa inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation
-
Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, et al. TNFa inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation. Am J Physiol Lung Cell Mol Physiol 2009;297: L586-L595.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Borges, V.M.1
Vandivier, R.W.2
McPhillips, K.A.3
Kench, J.A.4
Morimoto, K.5
Groshong, S.D.6
Richens, T.R.7
Graham, B.B.8
Muldrow, A.M.9
Van Heule, L.10
-
25
-
-
84856270064
-
Carbocisteine promotes phagocytosis of apoptotic cells by alveolar macrophages
-
Inoue M, Ishibashi Y, Nogawa H, Yasue T. Carbocisteine promotes phagocytosis of apoptotic cells by alveolar macrophages. Eur J Pharmacol 2012;677: 173-179.
-
(2012)
Eur J Pharmacol
, vol.677
, pp. 173-179
-
-
Inoue, M.1
Ishibashi, Y.2
Nogawa, H.3
Yasue, T.4
-
26
-
-
33947305316
-
Simvastatin increases neutrophil apoptosis and reduces inflammatory reaction after coronary surgery
-
Chello M, Anselmi A, Spadaccio C, Patti G, Goffredo C, Di Sciascio G, Covino E. Simvastatin increases neutrophil apoptosis and reduces inflammatory reaction after coronary surgery. Ann Thorac Surg 2007;83: 1374-1380.
-
(2007)
Ann Thorac Surg
, vol.83
, pp. 1374-1380
-
-
Chello, M.1
Anselmi, A.2
Spadaccio, C.3
Patti, G.4
Goffredo, C.5
Di Sciascio, G.6
Covino, E.7
-
27
-
-
33744906761
-
Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease
-
Morimoto K, Janssen WJ, Fessler MB, McPhillips KA, Borges VM, Bowler RP, Xiao YQ, Kench JA, Henson PM, Vandivier RW. Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. J Immunol 2006;176: 7657-7665.
-
(2006)
J Immunol
, vol.176
, pp. 7657-7665
-
-
Morimoto, K.1
Janssen, W.J.2
Fessler, M.B.3
McPhillips, K.A.4
Borges, V.M.5
Bowler, R.P.6
Xiao, Y.Q.7
Kench, J.A.8
Henson, P.M.9
Vandivier, R.W.10
-
28
-
-
84870454294
-
Assessment of pulmonary neutrophilic inflammation in emphysema by quantitative positron emission tomography
-
Subramanian DR, Jenkins L, Edgar R, Quraishi N, Stockley RA, Parr DG. Assessment of pulmonary neutrophilic inflammation in emphysema by quantitative positron emission tomography. Am J Respir Crit Care Med 2012;186: 1125-1132.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 1125-1132
-
-
Subramanian, D.R.1
Jenkins, L.2
Edgar, R.3
Quraishi, N.4
Stockley, R.A.5
Parr, D.G.6
-
29
-
-
78649615151
-
Transepithelial exit of leucocytes: Inflicting, reflecting or resolving airway inflammation?
-
Persson C, Uller L. Transepithelial exit of leucocytes: inflicting, reflecting or resolving airway inflammation? Thorax 2010;65: 1111-1115.
-
(2010)
Thorax
, vol.65
, pp. 1111-1115
-
-
Persson, C.1
Uller, L.2
-
30
-
-
0034822577
-
Neutrophil-mediated epithelial injury during transmigration: Role of elastase
-
Ginzberg HH, Cherapanov V, Dong Q, Cantin A, McCulloch CA, Shannon PT, Downey GP. Neutrophil-mediated epithelial injury during transmigration: role of elastase. Am J Physiol Gastrointest Liver Physiol 2001;281:G705-G717.
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.281
-
-
Ginzberg, H.H.1
Cherapanov, V.2
Dong, Q.3
Cantin, A.4
McCulloch, C.A.5
Shannon, P.T.6
Downey, G.P.7
-
31
-
-
80053159409
-
Neutrophil transmigration triggers repair of the lung epithelium via beta-catenin signaling
-
Zemans RL, Briones N, Campbell M, McClendon J, Young SK, Suzuki T, Yang IV, De Langhe S, Reynolds SD, Mason RJ, et al. Neutrophil transmigration triggers repair of the lung epithelium via beta-catenin signaling. Proc Natl Acad Sci USA 2011;108: 15990-15995.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 15990-15995
-
-
Zemans, R.L.1
Briones, N.2
Campbell, M.3
McClendon, J.4
Young, S.K.5
Suzuki, T.6
Yang, I.V.7
De Langhe, S.8
Reynolds, S.D.9
Mason, R.J.10
-
32
-
-
0036794862
-
Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
-
Donaldson GC, Seemungal TAR, Bhowmik A, Wedzicha JA. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002;57: 847-852.
-
(2002)
Thorax
, vol.57
, pp. 847-852
-
-
Donaldson, G.C.1
Seemungal, T.A.R.2
Bhowmik, A.3
Wedzicha, J.A.4
-
33
-
-
79953795292
-
Molecular diagnosis of respiratory tract infection in acute exacerbations of chronic obstructive pulmonary disease
-
Sethi S. Molecular diagnosis of respiratory tract infection in acute exacerbations of chronic obstructive pulmonary disease. Clin Infect Dis 2011;52:S290-S295.
-
(2011)
Clin Infect Dis
, vol.52
-
-
Sethi, S.1
-
34
-
-
3242751816
-
Persistent colonization by Haemophilus influenzae in chronic obstructive pulmonary disease
-
Murphy TF, Brauer AL, Schiffmacher AT, Sethi S. Persistent colonization by Haemophilus influenzae in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2004;170: 266-272.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 266-272
-
-
Murphy, T.F.1
Brauer, A.L.2
Schiffmacher, A.T.3
Sethi, S.4
-
35
-
-
71049141360
-
Moraxella catarrhalis acquisition, airway inflammation and protease-antiprotease balance in chronic obstructive pulmonary disease
-
Parameswaran GI, Wrona CT, Murphy TF, Sethi S. Moraxella catarrhalis acquisition, airway inflammation and protease-antiprotease balance in chronic obstructive pulmonary disease. BMC Infect Dis 2009;9:178.
-
(2009)
BMC Infect Dis
, vol.9
, pp. 178
-
-
Parameswaran, G.I.1
Wrona, C.T.2
Murphy, T.F.3
Sethi, S.4
-
36
-
-
0036727140
-
Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations
-
Patel IS, Seemungal TA, Wilks M, Lloyd-Owen SJ, Donaldson GC, Wedzicha JA. Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations. Thorax 2002;57: 759-764.
-
(2002)
Thorax
, vol.57
, pp. 759-764
-
-
Patel, I.S.1
Seemungal, T.A.2
Wilks, M.3
Lloyd-Owen, S.J.4
Donaldson, G.C.5
Wedzicha, J.A.6
-
37
-
-
0037447325
-
Airway bacterial load and FEV1 decline in patients with chronic obstructive pulmonary disease
-
Wilkinson TMA, Patel IS, Wilks M, Donaldson GC, Wedzicha JA. Airway bacterial load and FEV1 decline in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003;167: 1090-1095.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1090-1095
-
-
Wilkinson, T.M.A.1
Patel, I.S.2
Wilks, M.3
Donaldson, G.C.4
Wedzicha, J.A.5
-
38
-
-
2442533163
-
Impact of sputum bacteria on airway inflammation and health status in clinical stable COPD
-
Banerjee D, Khair OA, Honeybourne D. Impact of sputum bacteria on airway inflammation and health status in clinical stable COPD. Eur Respir J 2004;23: 685-691.
-
(2004)
Eur Respir J
, vol.23
, pp. 685-691
-
-
Banerjee, D.1
Khair, O.A.2
Honeybourne, D.3
-
39
-
-
0033835782
-
Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis
-
Hill AT, Campbell EJ, Hill SL, Bayley DL, Stockley RA. Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis. Am J Med 2000;109: 288-295.
-
(2000)
Am J Med
, vol.109
, pp. 288-295
-
-
Hill, A.T.1
Campbell, E.J.2
Hill, S.L.3
Bayley, D.L.4
Stockley, R.A.5
-
40
-
-
84867563577
-
Microbiome diversity in the bronchial tract of patients with chronic obstructive pulmonary disease
-
Cabrera-Rubio R, Garcia-Núñez M, Setó L, Antó JM, Moya A, Monsó E, Mira A. Microbiome diversity in the bronchial tract of patients with chronic obstructive pulmonary disease. J Clin Microbiol 2012; 50: 3562-3568.
-
(2012)
J Clin Microbiol
, vol.50
, pp. 3562-3568
-
-
Cabrera-Rubio, R.1
Garcia-Núñez, M.2
Setó, L.3
Antó, J.M.4
Moya, A.5
Monsó, E.6
Mira, A.7
-
41
-
-
84862800379
-
Significance of the microbiome in obstructive lung disease
-
Han MK, Huang YJ, Lipuma JJ, Boushey HA, Boucher RC, Cookson WO, Curtis JL, Erb-Downward J, Lynch SV, Sethi S, et al. Significance of the microbiome in obstructive lung disease. Thorax 2012;67: 456-463.
-
(2012)
Thorax
, vol.67
, pp. 456-463
-
-
Han, M.K.1
Huang, Y.J.2
Lipuma, J.J.3
Boushey, H.A.4
Boucher, R.C.5
Cookson, W.O.6
Curtis, J.L.7
Erb-Downward, J.8
Lynch, S.V.9
Sethi, S.10
-
42
-
-
84861399683
-
The lung tissue microbiome in chronic obstructive pulmonary disease
-
Sze MA, Dimitriu PA, Hayashi S, Elliott WM, McDonough JE, Gosselink JV, Cooper J, Sin DD, Mohn WW, Hogg JC. The lung tissue microbiome in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012;185: 1073-1080.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 1073-1080
-
-
Sze, M.A.1
Dimitriu, P.A.2
Hayashi, S.3
Elliott, W.M.4
McDonough, J.E.5
Gosselink, J.V.6
Cooper, J.7
Sin, D.D.8
Mohn, W.W.9
Hogg, J.C.10
-
43
-
-
56749157688
-
Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations
-
Seemungal TAR, Wilkinson TM, Hurst JR, Perera WR, Sapsford RJ, Wedzicha JA. Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations. Am J Respir Crit Care Med 2008;178: 1139-1147.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 1139-1147
-
-
Seemungal, T.A.R.1
Wilkinson, T.M.2
Hurst, J.R.3
Perera, W.R.4
Sapsford, R.J.5
Wedzicha, J.A.6
-
44
-
-
84865306933
-
Azithromycin and the risk of cardiovascular death
-
author reply 775
-
Albert RK, Connett J, Woodruff PG. Azithromycin and the risk of cardiovascular death. N Engl J Med 2012;367:773-774, author reply 775.
-
(2012)
N Engl J Med
, vol.367
, pp. 773-774
-
-
Albert, R.K.1
Connett, J.2
Woodruff, P.G.3
-
45
-
-
77954595517
-
Mechanisms of action and clinical application of macrolides as immunomodulatory medications
-
Kanoh S, Rubin BK. Mechanisms of action and clinical application of macrolides as immunomodulatory medications. Clin Microbiol Rev 2010;23: 590-615.
-
(2010)
Clin Microbiol Rev
, vol.23
, pp. 590-615
-
-
Kanoh, S.1
Rubin, B.K.2
-
46
-
-
61649098009
-
Azithromycin therapy for neutrophilic airways disease: Myth or magic?
-
Idris SF, Chilvers ER, Haworth C, McKeon D, Condliffe AM. Azithromycin therapy for neutrophilic airways disease: myth or magic? Thorax 2009;64: 186-189.
-
(2009)
Thorax
, vol.64
, pp. 186-189
-
-
Idris, S.F.1
Chilvers, E.R.2
Haworth, C.3
McKeon, D.4
Condliffe, A.M.5
-
47
-
-
79959747756
-
Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke
-
Mikura S, Wada H, Higaki M, Yasutake T, Ishii H, Kamiya S, Goto H. Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. Transl Res 2011;158: 30-37.
-
(2011)
Transl Res
, vol.158
, pp. 30-37
-
-
Mikura, S.1
Wada, H.2
Higaki, M.3
Yasutake, T.4
Ishii, H.5
Kamiya, S.6
Goto, H.7
-
48
-
-
0023940971
-
Evaluation of systemic host defense mechanisms in chronic bronchitis
-
Fietta A, Bersani C, De Rose V, Grassi FA, Mangiarotti P, Uccelli M, Grassi C. Evaluation of systemic host defense mechanisms in chronic bronchitis. Respiration 1988;53: 37-43.
-
(1988)
Respiration
, vol.53
, pp. 37-43
-
-
Fietta, A.1
Bersani, C.2
De Rose, V.3
Grassi, F.A.4
Mangiarotti, P.5
Uccelli, M.6
Grassi, C.7
-
49
-
-
0034948629
-
Defective natural killer and phagocytic activities in chronic obstructive pulmonary disease are restored by glycophosphopeptical (inmunoferón)
-
Prieto A, Reyes E, Bernstein ED, Martinez B, Monserrat J, Izquierdo JL, Callol L, de LUCAS P, Alvarez-Sala R, Alvarez-Sala JL, et al. Defective natural killer and phagocytic activities in chronic obstructive pulmonary disease are restored by glycophosphopeptical (inmunoferón). Am J Respir Crit Care Med 2001;163: 1578-1583.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1578-1583
-
-
Prieto, A.1
Reyes, E.2
Bernstein, E.D.3
Martinez, B.4
Monserrat, J.5
Izquierdo, J.L.6
Callol, L.7
De Lucas, P.8
Alvarez-Sala, R.9
Alvarez-Sala, J.L.10
-
50
-
-
0029012131
-
Phagocytosis and oxidative burst of granulocytes in the upper respiratory tract in chronic and acute inflammation
-
Müns G, Rubinstein I, Singer P. Phagocytosis and oxidative burst of granulocytes in the upper respiratory tract in chronic and acute inflammation. J Otolaryngol 1995;24: 105-110.
-
(1995)
J Otolaryngol
, vol.24
, pp. 105-110
-
-
Müns, G.1
Rubinstein, I.2
Singer, P.3
-
51
-
-
9644273804
-
Impact of cigarette smoke on clearance and inflammation after Pseudomonas aeruginosa infection
-
Drannik AG, Pouladi MA, Robbins CS, Goncharova SI, Kianpour S, Stämpfli MR. Impact of cigarette smoke on clearance and inflammation after Pseudomonas aeruginosa infection. Am J Respir Crit Care Med 2004;170: 1164-1171.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 1164-1171
-
-
Drannik, A.G.1
Pouladi, M.A.2
Robbins, C.S.3
Goncharova, S.I.4
Kianpour, S.5
Stämpfli, M.R.6
-
52
-
-
34447562582
-
Cigarette smoke extract-induced suppression of caspase-3-like activity impairs human neutrophil phagocytosis
-
Stringer KA, Tobias M, O'Neill HC, Franklin CC. Cigarette smoke extract-induced suppression of caspase-3-like activity impairs human neutrophil phagocytosis. Am J Physiol Lung Cell Mol Physiol 2007; 292:L1572-L1579.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Stringer, K.A.1
Tobias, M.2
O'neill, H.C.3
Franklin, C.C.4
-
53
-
-
0025374923
-
Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch
-
Tosi MF, Zakem H, Berger M. Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch. J Clin Invest 1990;86: 300-308.
-
(1990)
J Clin Invest
, vol.86
, pp. 300-308
-
-
Tosi, M.F.1
Zakem, H.2
Berger, M.3
-
54
-
-
79959284858
-
Toll-like receptor expression in smokers with and without COPD
-
Von Scheele I, Larsson K, Dahlén B, Billing B, Skedinger M, Lantz AS, Palmberg L. Toll-like receptor expression in smokers with and without COPD. Respir Med 2011;105: 1222-1230.
-
(2011)
Respir Med
, vol.105
, pp. 1222-1230
-
-
Von Scheele, I.1
Larsson, K.2
Dahlén, B.3
Billing, B.4
Skedinger, M.5
Lantz, A.S.6
Palmberg, L.7
-
55
-
-
79251558091
-
Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils
-
McGovern NN, Cowburn AS, Porter L, Walmsley SR, Summers C, Thompson AA, Anwar S, Willcocks LC, Whyte MK, Condliffe AM, Chilvers ER. Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils. J Immunol 2011;186: 453-463.
-
(2011)
J Immunol
, vol.186
, pp. 453-463
-
-
McGovern, N.N.1
Cowburn, A.S.2
Porter, L.3
Walmsley, S.R.4
Summers, C.5
Thompson, A.A.6
Anwar, S.7
Willcocks, L.C.8
Whyte, M.K.9
Condliffe, A.M.10
Chilvers, E.R.11
-
56
-
-
34547905794
-
Haemophilus influenzae induces neutrophil necrosis: A role in chronic obstructive pulmonary disease?
-
Naylor EJ, Bakstad D, Biffen M, Thong B, Calverley P, Scott S, Hart CA, Moots RJ, Edwards SW. Haemophilus influenzae induces neutrophil necrosis: a role in chronic obstructive pulmonary disease? Am J Respir Cell Mol Biol 2007;37: 135-143.
-
(2007)
Am J Respir Cell Mol Biol
, vol.37
, pp. 135-143
-
-
Naylor, E.J.1
Bakstad, D.2
Biffen, M.3
Thong, B.4
Calverley, P.5
Scott, S.6
Hart, C.A.7
Moots, R.J.8
Edwards, S.W.9
-
57
-
-
79955487961
-
Behavioral and structural differences in migrating peripheral neutrophils from patients with chronic obstructive pulmonary disease
-
Sapey E, Stockley JA, Greenwood H, Ahmad A, Bayley D, Lord JM, Insall RH, Stockley RA. Behavioral and structural differences in migrating peripheral neutrophils from patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2011;183: 1176-1186.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 1176-1186
-
-
Sapey, E.1
Stockley, J.A.2
Greenwood, H.3
Ahmad, A.4
Bayley, D.5
Lord, J.M.6
Insall, R.H.7
Stockley, R.A.8
-
58
-
-
0027174208
-
Control of exocytosis in early neutrophil activation
-
Sengeløv H, Kjeldsen L, Borregaard N. Control of exocytosis in early neutrophil activation. J Immunol 1993;150: 1535-1543.
-
(1993)
J Immunol
, vol.150
, pp. 1535-1543
-
-
Sengeløv, H.1
Kjeldsen, L.2
Borregaard, N.3
-
59
-
-
3042842747
-
Effect of priming on activation and localization of phospholipase D-1 in human neutrophils
-
Cadwallader KA, Uddin M, Condliffe AM, Cowburn AS, White JF, Skepper JN, Ktistakis NT, Chilvers ER. Effect of priming on activation and localization of phospholipase D-1 in human neutrophils. Eur J Biochem 2004;271: 2755-2764.
-
(2004)
Eur J Biochem
, vol.271
, pp. 2755-2764
-
-
Cadwallader, K.A.1
Uddin, M.2
Condliffe, A.M.3
Cowburn, A.S.4
White, J.F.5
Skepper, J.N.6
Ktistakis, N.T.7
Chilvers, E.R.8
-
60
-
-
0033848163
-
Monitoring of neutrophil priming in whole blood by antibodies isolated from a synthetic phage antibody library
-
Koenderman L, Kanters D, Maesen B, Raaijmakers J, Lammers JW, de Kruif J, Logtenberg T. Monitoring of neutrophil priming in whole blood by antibodies isolated from a synthetic phage antibody library. J Leukoc Biol 2000;68: 58-64.
-
(2000)
J Leukoc Biol
, vol.68
, pp. 58-64
-
-
Koenderman, L.1
Kanters, D.2
Maesen, B.3
Raaijmakers, J.4
Lammers, J.W.5
De Kruif, J.6
Logtenberg, T.7
-
61
-
-
33748187106
-
Expression of priming-associated cellular markers on neutrophils during an exacerbation of COPD
-
Oudijk E-JD, Gerritsen WB, Nijhuis EH, Kanters D, Maesen BL, Lammers JW, Koenderman L. Expression of priming-associated cellular markers on neutrophils during an exacerbation of COPD. Respir Med 2006;100: 1791-1799.
-
(2006)
Respir Med
, vol.100
, pp. 1791-1799
-
-
E-Jd, O.1
Gerritsen, W.B.2
Nijhuis, E.H.3
Kanters, D.4
Maesen, B.L.5
Lammers, J.W.6
Koenderman, L.7
-
62
-
-
0021321628
-
Nicotine is chemotactic for neutrophils and enhances neutrophil responsiveness to chemotactic peptides
-
Totti N III, McCusker KT, Campbell EJ, Griffin GL, Senior RM. Nicotine is chemotactic for neutrophils and enhances neutrophil responsiveness to chemotactic peptides. Science 1984;223: 169-171.
-
(1984)
Science
, vol.223
, pp. 169-171
-
-
Totti III, N.1
McCusker, K.T.2
Campbell, E.J.3
Griffin, G.L.4
Senior, R.M.5
-
63
-
-
0028361915
-
Nicotine-induced release of elastase and eicosanoids by human neutrophils
-
Seow WK, Thong YH, Nelson RD, MacFarlane GD, Herzberg MC. Nicotine-induced release of elastase and eicosanoids by human neutrophils. Inflammation 1994;18: 119-127.
-
(1994)
Inflammation
, vol.18
, pp. 119-127
-
-
Seow, W.K.1
Thong, Y.H.2
Nelson, R.D.3
Macfarlane, G.D.4
Herzberg, M.C.5
-
64
-
-
80052681561
-
Analysis of sputum markers in the evaluation of lung inflammation and functional impairment in symptomatic smokers and COPD patients
-
Paone G, Conti V, Vestri A, Leone A, Puglisi G, Benassi F, Brunetti G, Schmid G, Cammarella I, Terzano C. Analysis of sputum markers in the evaluation of lung inflammation and functional impairment in symptomatic smokers and COPD patients. Dis Markers 2011;31: 91-100.
-
(2011)
Dis Markers
, vol.31
, pp. 91-100
-
-
Paone, G.1
Conti, V.2
Vestri, A.3
Leone, A.4
Puglisi, G.5
Benassi, F.6
Brunetti, G.7
Schmid, G.8
Cammarella, I.9
Terzano, C.10
-
65
-
-
55249094894
-
Transient elevation of neutrophil proteinases in induced sputum during COPD exacerbation
-
Ilumets H, Rytilä PH, Sovijärvi AR, Tervahartiala T, Myllärniemi M, Sorsa TA, Kinnula VL. Transient elevation of neutrophil proteinases in induced sputum during COPD exacerbation. Scand J Clin Lab Invest 2008;68: 618-623.
-
(2008)
Scand J Clin Lab Invest
, vol.68
, pp. 618-623
-
-
Ilumets, H.1
Rytilä, P.H.2
Sovijärvi, A.R.3
Tervahartiala, T.4
Myllärniemi, M.5
Sorsa, T.A.6
Kinnula, V.L.7
-
66
-
-
0032989453
-
Neutrophil granule proteins in bronchoalveolar lavage fluid from subjects with subclinical emphysema
-
Betsuyaku T, Nishimura M, Takeyabu K, Tanino M, Venge P, Xu S, Kawakami Y. Neutrophil granule proteins in bronchoalveolar lavage fluid from subjects with subclinical emphysema. Am J Respir Crit Care Med 1999;159: 1985-1991.
-
(1999)
Am J Respir Crit Care Med
, vol.159
, pp. 1985-1991
-
-
Betsuyaku, T.1
Nishimura, M.2
Takeyabu, K.3
Tanino, M.4
Venge, P.5
Xu, S.6
Kawakami, Y.7
-
67
-
-
0031059872
-
Granulocyte activation markers in induced sputum: Comparison between chronic obstructive pulmonary disease, asthma, and normal subjects
-
Keatings VM, Barnes PJ. Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma, and normal subjects. Am J Respir Crit Care Med 1997;155: 449-453.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 449-453
-
-
Keatings, V.M.1
Barnes, P.J.2
-
68
-
-
77957857333
-
Neutrophil gelatinase-associated lipocalin: A biomarker in COPD
-
Eagan TM, Damås JK, Ueland T, Voll-Aanerud M, Mollnes TE, Hardie JA, Bakke PS, Aukrust P. Neutrophil gelatinase-associated lipocalin: a biomarker in COPD. Chest 2010;138: 888-895.
-
(2010)
Chest
, vol.138
, pp. 888-895
-
-
Eagan, T.M.1
Damås, J.K.2
Ueland, T.3
Voll-Aanerud, M.4
Mollnes, T.E.5
Hardie, J.A.6
Bakke, P.S.7
Aukrust, P.8
-
69
-
-
69749086251
-
N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD
-
O'Reilly P, Jackson PL, Noerager B, Parker S, Dransfield M, Gaggar A, Blalock JE. N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD. Respir Res 2009;10:38.
-
(2009)
Respir Res
, vol.10
, pp. 38
-
-
O'reilly, P.1
Jackson, P.L.2
Noerager, B.3
Parker, S.4
Dransfield, M.5
Gaggar, A.6
Blalock, J.E.7
-
70
-
-
79960617712
-
The fibrinogen cleavage product Aa-Val360, a specific marker of neutrophil elastase activity in vivo
-
Carter RI, Mumford RA, Treonze KM, Finke PE, Davies P, Si Q, Humes JL, Dirksen A, Piitulainen E, Ahmad A, et al. The fibrinogen cleavage product Aa-Val360, a specific marker of neutrophil elastase activity in vivo. Thorax 2011;66: 686-691.
-
(2011)
Thorax
, vol.66
, pp. 686-691
-
-
Carter, R.I.1
Mumford, R.A.2
Treonze, K.M.3
Finke, P.E.4
Davies, P.5
Si, Q.6
Humes, J.L.7
Dirksen, A.8
Piitulainen, E.9
Ahmad, A.10
-
72
-
-
0034144636
-
Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G
-
Tkalcevic J, Novelli M, Phylactides M, Iredale JP, Segal AW, Roes J. Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G. Immunity 2000;12: 201-210.
-
(2000)
Immunity
, vol.12
, pp. 201-210
-
-
Tkalcevic, J.1
Novelli, M.2
Phylactides, M.3
Iredale, J.P.4
Segal, A.W.5
Roes, J.6
-
73
-
-
0023937510
-
Structure, function, and control of neutrophil proteinases
-
Travis J. Structure, function, and control of neutrophil proteinases. Am J Med 1988;84: 37-42.
-
(1988)
Am J Med
, vol.84
, pp. 37-42
-
-
Travis, J.1
-
74
-
-
0032717991
-
Neutrophils and protease/antiprotease imbalance
-
Stockley RA. Neutrophils and protease/antiprotease imbalance. Am J Respir Crit Care Med 1999;160:S49-S52.
-
(1999)
Am J Respir Crit Care Med
, vol.160
-
-
Stockley, R.A.1
-
75
-
-
0028865394
-
Cell surface-bound elastase and cathepsin G on human neutrophils: A novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases
-
Owen CA, Campbell MA, Sannes PL, Boukedes SS, Campbell EJ. Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases. J Cell Biol 1995;131: 775-789.
-
(1995)
J Cell Biol
, vol.131
, pp. 775-789
-
-
Owen, C.A.1
Campbell, M.A.2
Sannes, P.L.3
Boukedes, S.S.4
Campbell, E.J.5
-
76
-
-
33745559712
-
Neutrophil serine proteases: Specific regulators of inflammation
-
Pham CTN. Neutrophil serine proteases: specific regulators of inflammation. Nat Rev Immunol 2006;6: 541-550.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 541-550
-
-
Pham, C.T.N.1
-
77
-
-
0032743423
-
Quantum proteolysis by neutrophils: Implications for pulmonary emphysema in alpha 1-antitrypsin deficiency
-
Campbell EJ, Campbell MA, Boukedes SS, Owen CA. Quantum proteolysis by neutrophils: implications for pulmonary emphysema in alpha 1-antitrypsin deficiency. J Clin Invest 1999;104: 337-344.
-
(1999)
J Clin Invest
, vol.104
, pp. 337-344
-
-
Campbell, E.J.1
Campbell, M.A.2
Boukedes, S.S.3
Owen, C.A.4
-
78
-
-
0025982378
-
Effects of human neutrophil elastase and Pseudomonas aeruginosa proteinases on human respiratory epithelium
-
Amitani R, Wilson R, Rutman A, Read R, Ward C, Burnett D, Stockley RA, Cole PJ. Effects of human neutrophil elastase and Pseudomonas aeruginosa proteinases on human respiratory epithelium. Am J Respir Cell Mol Biol 1991;4: 26-32.
-
(1991)
Am J Respir Cell Mol Biol
, vol.4
, pp. 26-32
-
-
Amitani, R.1
Wilson, R.2
Rutman, A.3
Read, R.4
Ward, C.5
Burnett, D.6
Stockley, R.A.7
Cole, P.J.8
-
79
-
-
0021924332
-
Effect of combined human neutrophil cathepsin G and elastase on induction of secretory cell metaplasia and emphysema in hamsters, with in vitro observations on elastolysis by these enzymes
-
Lucey EC, Stone PJ, Breuer R, Christensen TG, Calore JD, Catanese A, Franzblau C, Snider GL. Effect of combined human neutrophil cathepsin G and elastase on induction of secretory cell metaplasia and emphysema in hamsters, with in vitro observations on elastolysis by these enzymes. Am Rev Respir Dis 1985;132: 362-366.
-
(1985)
Am Rev Respir Dis
, vol.132
, pp. 362-366
-
-
Lucey, E.C.1
Stone, P.J.2
Breuer, R.3
Christensen, T.G.4
Calore, J.D.5
Catanese, A.6
Franzblau, C.7
Snider, G.L.8
-
80
-
-
0021135892
-
Reduction of ciliary beat frequency in vitro by sputum from patients with bronchiectasis: A serine proteinase effect
-
Smallman LA, Hill SL, Stockley RA. Reduction of ciliary beat frequency in vitro by sputum from patients with bronchiectasis: a serine proteinase effect. Thorax 1984;39: 663-667.
-
(1984)
Thorax
, vol.39
, pp. 663-667
-
-
Smallman, L.A.1
Hill, S.L.2
Stockley, R.A.3
-
81
-
-
0019453831
-
Antielastases of the human alveolar structures: Implications for the protease-antiprotease theory of emphysema
-
Gadek JE, Fells GA, Zimmerman RL, Rennard SI, Crystal RG. Antielastases of the human alveolar structures: implications for the protease-antiprotease theory of emphysema. J Clin Invest 1981;68: 889-898.
-
(1981)
J Clin Invest
, vol.68
, pp. 889-898
-
-
Gadek, J.E.1
Fells, G.A.2
Zimmerman, R.L.3
Rennard, S.I.4
Crystal, R.G.5
-
83
-
-
0022638237
-
Alpha 1-antitrypsin Pi-types in 965 COPD patients
-
Lieberman J, Winter B, Sastre A. Alpha 1-antitrypsin Pi-types in 965 COPD patients. Chest 1986;89: 370-373.
-
(1986)
Chest
, vol.89
, pp. 370-373
-
-
Lieberman, J.1
Winter, B.2
Sastre, A.3
-
84
-
-
0017129012
-
Elastase, collagenase, emphysema, and alpha1-antitrypsin deficiency
-
Lieberman J. Elastase, collagenase, emphysema, and alpha1-antitrypsin deficiency. Chest 1976;70: 62-67.
-
(1976)
Chest
, vol.70
, pp. 62-67
-
-
Lieberman, J.1
-
85
-
-
70350450961
-
Augmentation therapy for alpha1 antitrypsin deficiency: A metaanalysis
-
Chapman KR, Stockley RA, Dawkins C, Wilkes MM, Navickis RJ. Augmentation therapy for alpha1 antitrypsin deficiency: a metaanalysis. COPD 2009;6: 177-184.
-
(2009)
COPD
, vol.6
, pp. 177-184
-
-
Chapman, K.R.1
Stockley, R.A.2
Dawkins, C.3
Wilkes, M.M.4
Navickis, R.J.5
-
87
-
-
78650096176
-
Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases
-
Korkmaz B, Horwitz MS, Jenne DE, Gauthier F. Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases. Pharmacol Rev 2010;62: 726-759.
-
(2010)
Pharmacol Rev
, vol.62
, pp. 726-759
-
-
Korkmaz, B.1
Horwitz, M.S.2
Jenne, D.E.3
Gauthier, F.4
-
88
-
-
0344413022
-
Neutrophil elastase contributes to cigarette smokeinduced emphysema in mice
-
Shapiro SD, Goldstein NM, Houghton AM, Kobayashi DK, Kelley D, Belaaouaj A. Neutrophil elastase contributes to cigarette smokeinduced emphysema in mice. Am J Pathol 2003;163: 2329-2335.
-
(2003)
Am J Pathol
, vol.163
, pp. 2329-2335
-
-
Shapiro, S.D.1
Goldstein, N.M.2
Houghton, A.M.3
Kobayashi, D.K.4
Kelley, D.5
Belaaouaj, A.6
-
89
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997;277: 2002-2004.
-
(1997)
Science
, vol.277
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, S.D.4
-
90
-
-
80053169347
-
AZD9668: Pharmacological characterization of a novel oral inhibitor of neutrophil elastase
-
Stevens T, Ekholm K, Gränse M, Lindahl M, Kozma V, Jungar C, Ottosson T, Falk-Håkansson H, Churg A, Wright JL, et al. AZD9668: pharmacological characterization of a novel oral inhibitor of neutrophil elastase. J Pharmacol Exp Ther 2011;339: 313-320.
-
(2011)
J Pharmacol Exp Ther
, vol.339
, pp. 313-320
-
-
Stevens, T.1
Ekholm, K.2
Gränse, M.3
Lindahl, M.4
Kozma, V.5
Jungar, C.6
Ottosson, T.7
Falk-Håkansson, H.8
Churg, A.9
Wright, J.L.10
-
91
-
-
84857911015
-
AZD9668, a neutrophil elastase inhibitor, plus ongoing budesonide/formoterol in patients with COPD
-
Kuna P, Jenkins M, O'Brien CD, Fahy WA. AZD9668, a neutrophil elastase inhibitor, plus ongoing budesonide/formoterol in patients with COPD. Respir Med 2012;106: 531-539.
-
(2012)
Respir Med
, vol.106
, pp. 531-539
-
-
Kuna, P.1
Jenkins, M.2
O'brien, C.D.3
Fahy, W.A.4
-
92
-
-
84859373133
-
A randomised, placebo-controlled, dose-finding study of AZD9668, an oral inhibitor of neutrophil elastase, in patients with chronic obstructive pulmonary disease treated with tiotropium
-
Vogelmeier C, Aquino TO, O'Brien CD, Perrett J, Gunawardena KA. A randomised, placebo-controlled, dose-finding study of AZD9668, an oral inhibitor of neutrophil elastase, in patients with chronic obstructive pulmonary disease treated with tiotropium. COPD 2012;9: 111-120.
-
(2012)
COPD
, vol.9
, pp. 111-120
-
-
Vogelmeier, C.1
Aquino, T.O.2
O'brien, C.D.3
Perrett, J.4
Gunawardena, K.A.5
-
93
-
-
0037135707
-
Defensin-rich granules of human neutrophils: Characterization of secretory properties
-
Faurschou M, Sørensen OE, Johnsen AH, Askaa J, Borregaard N. Defensin-rich granules of human neutrophils: characterization of secretory properties. Biochim Biophys Acta 2002;1591: 29-35.
-
(2002)
Biochim Biophys Acta
, vol.1591
, pp. 29-35
-
-
Faurschou, M.1
Sørensen, O.E.2
Johnsen, A.H.3
Askaa, J.4
Borregaard, N.5
-
94
-
-
0022272160
-
Free-radical chemistry of cigarette smoke and its toxicological implications
-
Church DF, Pryor WA. Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect 1985;64: 111-126.
-
(1985)
Environ Health Perspect
, vol.64
, pp. 111-126
-
-
Church, D.F.1
Pryor, W.A.2
-
95
-
-
0024351881
-
Quantitative analysis of the hydrogen peroxide formed in aqueous cigarette tar extracts
-
Nakayama T, Church DF, Pryor WA. Quantitative analysis of the hydrogen peroxide formed in aqueous cigarette tar extracts. Free Radic Biol Med 1989;7: 9-15.
-
(1989)
Free Radic Biol Med
, vol.7
, pp. 9-15
-
-
Nakayama, T.1
Church, D.F.2
Pryor, W.A.3
-
96
-
-
0036679823
-
Tyrosyl radical production by myeloperoxidase: A phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteins
-
Heinecke JW. Tyrosyl radical production by myeloperoxidase: a phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteins. Toxicology 2002;177: 11-22.
-
(2002)
Toxicology
, vol.177
, pp. 11-22
-
-
Heinecke, J.W.1
-
97
-
-
0021967819
-
Increased neutrophil myeloperoxidase activity associated with cigarette smoking
-
Bridges RB, Fu MC, Rehm SR. Increased neutrophil myeloperoxidase activity associated with cigarette smoking. Eur J Respir Dis 1985;67: 84-93.
-
(1985)
Eur J Respir Dis
, vol.67
, pp. 84-93
-
-
Bridges, R.B.1
Fu, M.C.2
Rehm, S.R.3
-
98
-
-
0034713175
-
The endothelium and cytokine secretion: The role of peroxidases as immunoregulators
-
Lefkowitz DL, Roberts E, Grattendick K, Schwab C, Stuart R, Lincoln J, Allen RC, Moguilevsky N, Bollen A, Lefkowitz SS. The endothelium and cytokine secretion: the role of peroxidases as immunoregulators. Cell Immunol 2000;202: 23-30.
-
(2000)
Cell Immunol
, vol.202
, pp. 23-30
-
-
Lefkowitz, D.L.1
Roberts, E.2
Grattendick, K.3
Schwab, C.4
Stuart, R.5
Lincoln, J.6
Allen, R.C.7
Moguilevsky, N.8
Bollen, A.9
Lefkowitz, S.S.10
-
99
-
-
0035135617
-
Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidants
-
Yang JJ, Preston GA, Pendergraft WF, Segelmark M, Heeringa P, Hogan SL, Jennette JC, Falk RJ. Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidants. Am J Pathol 2001;158: 581-592.
-
(2001)
Am J Pathol
, vol.158
, pp. 581-592
-
-
Yang, J.J.1
Preston, G.A.2
Pendergraft, W.F.3
Segelmark, M.4
Heeringa, P.5
Hogan, S.L.6
Jennette, J.C.7
Falk, R.J.8
-
100
-
-
78650475060
-
3-Chlorotyrosine in sputum of COPD patients: Relationship with airway inflammation
-
O'Donnell C, Newbold P, White P, Thong B, Stone H, Stockley RA. 3-Chlorotyrosine in sputum of COPD patients: relationship with airway inflammation. COPD 2010;7: 411-417.
-
(2010)
COPD
, vol.7
, pp. 411-417
-
-
O'donnell, C.1
Newbold, P.2
White, P.3
Thong, B.4
Stone, H.5
Stockley, R.A.6
-
101
-
-
84855280797
-
Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease
-
Churg A, Marshall CV, Sin DD, Bolton S, Zhou S, Thain K, Cadogan EB, Maltby J, Soars MG, Mallinder PR, et al. Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012;185: 34-43.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 34-43
-
-
Churg, A.1
Marshall, C.V.2
Sin, D.D.3
Bolton, S.4
Zhou, S.5
Thain, K.6
Cadogan, E.B.7
Maltby, J.8
Soars, M.G.9
Mallinder, P.R.10
-
102
-
-
82755187146
-
Everything prevents emphysema: Are animal models of cigarette smoke-induced chronic obstructive pulmonary disease any use?
-
Churg A, Sin DD, Wright JL. Everything prevents emphysema: are animal models of cigarette smoke-induced chronic obstructive pulmonary disease any use? Am J Respir Cell Mol Biol 2011;45: 1111-1115.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 1111-1115
-
-
Churg, A.1
Sin, D.D.2
Wright, J.L.3
-
103
-
-
0035877649
-
Subcellular distribution and cytokine- and chemokine-regulated secretion of leukolysin/MT6-MMP/MMP-25 in neutrophils
-
Kang T, Yi J, Guo A, Wang X, Overall CM, Jiang W, Elde R, Borregaard N, Pei D. Subcellular distribution and cytokine- and chemokine-regulated secretion of leukolysin/MT6-MMP/MMP-25 in neutrophils. J Biol Chem 2001;276: 21960-21968.
-
(2001)
J Biol Chem
, vol.276
, pp. 21960-21968
-
-
Kang, T.1
Yi, J.2
Guo, A.3
Wang, X.4
Overall, C.M.5
Jiang, W.6
Elde, R.7
Borregaard, N.8
Pei, D.9
-
104
-
-
0030811545
-
Elevated levels of matrix metalloproteinases in bronchoalveolar lavage fluid of emphysematous patients
-
Finlay GA, Russell KJ, McMahon KJ, D'arcy EM, Masterson JB, FitzGerald MX, O'Connor CM. Elevated levels of matrix metalloproteinases in bronchoalveolar lavage fluid of emphysematous patients. Thorax 1997;52: 502-506.
-
(1997)
Thorax
, vol.52
, pp. 502-506
-
-
Finlay, G.A.1
Russell, K.J.2
McMahon, K.J.3
D'arcy, E.M.4
Masterson, J.B.5
Fitzgerald, M.X.6
O'connor, C.M.7
-
105
-
-
29944444498
-
MMP-9, TIMP-1 and inflammatory cells in sputum from COPD patients during exacerbation
-
Mercer P, Shute JK, Bhowmik A, Donaldson GC, Wedzicha JA, Warner JA. MMP-9, TIMP-1 and inflammatory cells in sputum from COPD patients during exacerbation. Respir Res 2005;6:151.
-
(2005)
Respir Res
, vol.6
, pp. 151
-
-
Mercer, P.1
Shute, J.K.2
Bhowmik, A.3
Donaldson, G.C.4
Wedzicha, J.A.5
Warner, J.A.6
-
106
-
-
0032417102
-
Sputum metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis
-
Vignola AM, Riccobono L, Mirabella A, Profita M, Chanez P, Bellia V, Mautino G, D'accardi P, Bousquet J, Bonsignore G. Sputum metalloproteinase-9/ tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis. Am J Respir Crit Care Med 1998;158: 1945-1950.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1945-1950
-
-
Vignola, A.M.1
Riccobono, L.2
Mirabella, A.3
Profita, M.4
Chanez, P.5
Bellia, V.6
Mautino, G.7
D'accardi, P.8
Bousquet, J.9
Bonsignore, G.10
-
107
-
-
10444274041
-
Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD
-
Vernooy JHJ, Lindeman JHN, Jacobs JA, Hanemaaijer R, Wouters EFM. Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD. Chest 2004;126: 1802-1810.
-
(2004)
Chest
, vol.126
, pp. 1802-1810
-
-
Vernooy, J.H.J.1
Lindeman, J.H.N.2
Jacobs, J.A.3
Hanemaaijer, R.4
Wouters, E.F.M.5
-
108
-
-
0025808816
-
Purification and identification of 91-kDa neutrophil gelatinase: Release by the activating peptide interleukin-8
-
Masure S, Proost P, Van Damme J, Opdenakker G. Purification and identification of 91-kDa neutrophil gelatinase: release by the activating peptide interleukin-8. Eur J Biochem 1991;198: 391-398.
-
(1991)
Eur J Biochem
, vol.198
, pp. 391-398
-
-
Masure, S.1
Proost, P.2
Van Damme, J.3
Opdenakker, G.4
-
109
-
-
84857823945
-
Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD
-
Vlahos R, Wark PAB, Anderson GP, Bozinovski S. Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD. PLoS ONE 2012;7:e33277.
-
(2012)
PLoS ONE
, vol.7
-
-
Vlahos, R.1
Wark, P.A.B.2
Anderson, G.P.3
Bozinovski, S.4
-
110
-
-
0029019838
-
Preferential inactivation of tissue inhibitor of metalloproteinases-1 that is bound to the precursor of matrix metalloproteinase 9 (progelatinase B) by human neutrophil elastase
-
Itoh Y, Nagase H. Preferential inactivation of tissue inhibitor of metalloproteinases-1 that is bound to the precursor of matrix metalloproteinase 9 (progelatinase B) by human neutrophil elastase. J Biol Chem 1995;270: 16518-16521.
-
(1995)
J Biol Chem
, vol.270
, pp. 16518-16521
-
-
Itoh, Y.1
Nagase, H.2
-
111
-
-
60249098083
-
C-reactive protein correlates with tissue oxygen availability in patients with stable COPD
-
Baldi S, Pinna GD,Mombaruzzo P, Biglieri M, DeMartini A, Palange P. C-reactive protein correlates with tissue oxygen availability in patients with stable COPD. Int J Chron Obstruct Pulmon Dis 2008;3: 745-751.
-
(2008)
Int J Chron Obstruct Pulmon Dis
, vol.3
, pp. 745-751
-
-
Baldi, S.1
Pinna, G.D.2
Mombaruzzo, P.3
Biglieri, M.4
Demartini, A.5
Palange, P.6
-
112
-
-
77954716651
-
The effects of hypoxia on markers of coagulation and systemic inflammation in patients with COPD
-
Sabit R, Thomas P, Shale DJ, Collins P, Linnane SJ. The effects of hypoxia on markers of coagulation and systemic inflammation in patients with COPD. Chest 2010;138: 47-51.
-
(2010)
Chest
, vol.138
, pp. 47-51
-
-
Sabit, R.1
Thomas, P.2
Shale, D.J.3
Collins, P.4
Linnane, S.J.5
-
113
-
-
0037100063
-
Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: Correlation with tumor oxygenation
-
Haugland HK, Vukovic V, Pintilie M, Fyles AW, Milosevic M, Hill RP, Hedley DW. Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation. Int J Radiat Oncol Biol Phys 2002;53: 854-861.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.53
, pp. 854-861
-
-
Haugland, H.K.1
Vukovic, V.2
Pintilie, M.3
Fyles, A.W.4
Milosevic, M.5
Hill, R.P.6
Hedley, D.W.7
-
115
-
-
34848856029
-
Association of progressive structural changes in the bronchial epithelium with subepithelial fibrous remodeling: A potential role for hypoxia
-
Polosukhin VV, Lawson WE, Milstone AP, Egunova SM, Kulipanov AG, Tchuvakin SG, Massion PP, Blackwell TS. Association of progressive structural changes in the bronchial epithelium with subepithelial fibrous remodeling: a potential role for hypoxia. Virchows Arch 2007;451: 793-803.
-
(2007)
Virchows Arch
, vol.451
, pp. 793-803
-
-
Polosukhin, V.V.1
Lawson, W.E.2
Milstone, A.P.3
Egunova, S.M.4
Kulipanov, A.G.5
Tchuvakin, S.G.6
Massion, P.P.7
Blackwell, T.S.8
-
116
-
-
79955868497
-
Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium
-
Polosukhin VV, Cates JM, Lawson WE, Milstone AP, Matafonov AG, Massion PP, Lee JW, Randell SH, Blackwell TS. Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium. J Pathol 2011;224: 203-211.
-
(2011)
J Pathol
, vol.224
, pp. 203-211
-
-
Polosukhin, V.V.1
Cates, J.M.2
Lawson, W.E.3
Milstone, A.P.4
Matafonov, A.G.5
Massion, P.P.6
Lee, J.W.7
Randell, S.H.8
Blackwell, T.S.9
-
117
-
-
79960683641
-
Activation of hypoxia-inducible factor-1a (Hif-1a) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model
-
Elks PM, van Eeden FJ, Dixon G, Wang X, Reyes-Aldasoro CC, Ingham PW, Whyte MK, Walmsley SR, Renshaw SA. Activation of hypoxia-inducible factor-1a (Hif-1a) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model. Blood 2011;118: 712-722.
-
(2011)
Blood
, vol.118
, pp. 712-722
-
-
Elks, P.M.1
Van Eeden, F.J.2
Dixon, G.3
Wang, X.4
Reyes-Aldasoro, C.C.5
Ingham, P.W.6
Whyte, M.K.7
Walmsley, S.R.8
Renshaw, S.A.9
-
118
-
-
0029086009
-
Hypoxia prolongs neutrophil survival in vitro
-
Hannah S, Mecklenburgh K, Rahman I, Bellingan GJ, Greening A, Haslett C, Chilvers ER. Hypoxia prolongs neutrophil survival in vitro. FEBS Lett 1995;372: 233-237.
-
(1995)
FEBS Lett
, vol.372
, pp. 233-237
-
-
Hannah, S.1
Mecklenburgh, K.2
Rahman, I.3
Bellingan, G.J.4
Greening, A.5
Haslett, C.6
Chilvers, E.R.7
-
119
-
-
0043172315
-
Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: Implications for the resolution of inflammation
-
Heasman SJ, Giles KM, Ward C, Rossi AG, Haslett C, Dransfield I. Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inflammation. J Endocrinol 2003;178: 29-36.
-
(2003)
J Endocrinol
, vol.178
, pp. 29-36
-
-
Heasman, S.J.1
Giles, K.M.2
Ward, C.3
Rossi, A.G.4
Haslett, C.5
Dransfield, I.6
-
120
-
-
84859469853
-
Hypoxia sensitization of hepatocytes to neutrophil elastase-mediated cell death depends on MAPKs and HIF-1a
-
Sparkenbaugh EM, Ganey PE, Roth RA. Hypoxia sensitization of hepatocytes to neutrophil elastase-mediated cell death depends on MAPKs and HIF-1a. Am J Physiol Gastrointest Liver Physiol 2012; 302:G748-G757.
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
-
-
Sparkenbaugh, E.M.1
Ganey, P.E.2
Roth, R.A.3
-
121
-
-
27944493278
-
Hypoxia suppresses elastin repair by rat lung fibroblasts
-
Berk JL, Hatch CA, Morris SM, Stone PJ, Goldstein RH. Hypoxia suppresses elastin repair by rat lung fibroblasts. Am J Physiol Lung Cell Mol Physiol 2005;289:L931-L936.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.289
-
-
Berk, J.L.1
Hatch, C.A.2
Morris, S.M.3
Stone, P.J.4
Goldstein, R.H.5
-
122
-
-
78651431729
-
Systemic manifestations of COPD
-
Nussbaumer-Ochsner Y, Rabe KF. Systemic manifestations of COPD. Chest 2011;139: 165-173.
-
(2011)
Chest
, vol.139
, pp. 165-173
-
-
Nussbaumer-Ochsner, Y.1
Rabe, K.F.2
-
123
-
-
84859488830
-
Interstitial lung abnormalities and reduced exercise capacity
-
Doyle TJ, Washko GR, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Divo MJ, Celli BR, Sciurba FC, Silverman EK, et al. Interstitial lung abnormalities and reduced exercise capacity. Am J Respir Crit Care Med 2012;185: 756-762.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 756-762
-
-
Doyle, T.J.1
Washko, G.R.2
Fernandez, I.E.3
Nishino, M.4
Okajima, Y.5
Yamashiro, T.6
Divo, M.J.7
Celli, B.R.8
Sciurba, F.C.9
Silverman, E.K.10
-
124
-
-
84865057786
-
Inflammatory and repair serum biomarker pattern: Association to clinical outcomes in COPD
-
Pinto-Plata V, Casanova C, Müllerova H, de Torres JP, Corado H, Varo N, Cordoba E, Zeineldine S, Paz H, Baz R, et al. Inflammatory and repair serum biomarker pattern: association to clinical outcomes in COPD. Respir Res 2012;13:71.
-
(2012)
Respir Res
, vol.13
, pp. 71
-
-
Pinto-Plata, V.1
Casanova, C.2
Müllerova, H.3
De Torres, J.P.4
Corado, H.5
Varo, N.6
Cordoba, E.7
Zeineldine, S.8
Paz, H.9
Baz, R.10
-
125
-
-
84862203625
-
Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity
-
Cockayne DA, Cheng DT, Waschki B, Sridhar S, Ravindran P, Hilton H, Kourteva G, Bitter H, Pillai SG, Visvanathan S, et al. Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity. PLoS ONE 2012;7:e38629.
-
(2012)
PLoS ONE
, vol.7
-
-
Cockayne, D.A.1
Cheng, D.T.2
Waschki, B.3
Sridhar, S.4
Ravindran, P.5
Hilton, H.6
Kourteva, G.7
Bitter, H.8
Pillai, S.G.9
Visvanathan, S.10
-
126
-
-
22044433727
-
Systemic inflammation in COPD visualised by gene profiling in peripheral blood neutrophils
-
Oudijk E-JD, Nijhuis EH, Zwank MD, van de Graaf EA, Mager HJ, Coffer PJ, Lammers JW, Koenderman L. Systemic inflammation in COPD visualised by gene profiling in peripheral blood neutrophils. Thorax 2005;60: 538-544.
-
(2005)
Thorax
, vol.60
, pp. 538-544
-
-
E-Jd, O.1
Nijhuis, E.H.2
Zwank, M.D.3
Van De Graaf, E.A.4
Mager, H.J.5
Coffer, P.J.6
Lammers, J.W.7
Koenderman, L.8
-
127
-
-
33748693876
-
Neutrophil cytoskeletal rearrangements during capillary sequestration in bacterial pneumonia in rats
-
Yoshida K, Kondo R, Wang Q, Doerschuk CM. Neutrophil cytoskeletal rearrangements during capillary sequestration in bacterial pneumonia in rats. Am J Respir Crit Care Med 2006;174: 689-698.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 689-698
-
-
Yoshida, K.1
Kondo, R.2
Wang, Q.3
Doerschuk, C.M.4
-
128
-
-
79957993712
-
Establishing the pulmonary transit time of primed and unprimed neutrophils in man
-
Summers C, White J, Singh N, Mackenzie I, Johnston A, Solanki C, Balan K, Peters AM, Chilvers ER. Establishing the pulmonary transit time of primed and unprimed neutrophils in man. Thorax 2009;64:A3.
-
(2009)
Thorax
, vol.64
-
-
Summers, C.1
White, J.2
Singh, N.3
Mackenzie, I.4
Johnston, A.5
Solanki, C.6
Balan, K.7
Peters, A.M.8
Chilvers, E.R.9
-
129
-
-
84866669318
-
Functional redundancy of class i phosphoinositide 3-kinase (PI3K) Isoforms in signaling growth factor-mediated human neutrophil survival
-
Juss JK, Hayhoe RP, Owen CE, Bruce I, Walmsley SR, Cowburn AS, Kulkarni S, Boyle KB, Stephens L, Hawkins PT, et al. Functional redundancy of class i phosphoinositide 3-kinase (PI3K) Isoforms in signaling growth factor-mediated human neutrophil survival. PLoS ONE 2012;7:e45933.
-
(2012)
PLoS ONE
, vol.7
-
-
Juss, J.K.1
Hayhoe, R.P.2
Owen, C.E.3
Bruce, I.4
Walmsley, S.R.5
Cowburn, A.S.6
Kulkarni, S.7
Boyle, K.B.8
Stephens, L.9
Hawkins, P.T.10
-
130
-
-
33746585705
-
Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD
-
Rytilä P, Rehn T, Ilumets H, Rouhos A, Sovijärvi A, Myllärniemi M, Kinnula VL. Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD. Respir Res 2006;7:69.
-
(2006)
Respir Res
, vol.7
, pp. 69
-
-
Rytilä, P.1
Rehn, T.2
Ilumets, H.3
Rouhos, A.4
Sovijärvi, A.5
Myllärniemi, M.6
Kinnula, V.L.7
-
131
-
-
67649200156
-
Increased apoptosis of neutrophils in induced sputum of COPD patients
-
Makris D, Vrekoussis T, Izoldi M, Alexandra K, Katerina D, Dimitris T, Michalis A, Tzortzaki E, Siafakas NM, Tzanakis N. Increased apoptosis of neutrophils in induced sputum of COPD patients. Respir Med 2009;103: 1130-1135.
-
(2009)
Respir Med
, vol.103
, pp. 1130-1135
-
-
Makris, D.1
Vrekoussis, T.2
Izoldi, M.3
Alexandra, K.4
Katerina, D.5
Dimitris, T.6
Michalis, A.7
Tzortzaki, E.8
Siafakas, N.M.9
Tzanakis, N.10
-
132
-
-
65649116604
-
Dysregulated apoptosis and NFkappaB expression in COPD subjects
-
Brown V, Elborn JS, Bradley J, Ennis M. Dysregulated apoptosis and NFkappaB expression in COPD subjects. Respir Res 2009;10:24.
-
(2009)
Respir Res
, vol.10
, pp. 24
-
-
Brown, V.1
Elborn, J.S.2
Bradley, J.3
Ennis, M.4
-
133
-
-
84868615760
-
Inflammatory and satellite cells in the quadriceps of patients with COPD and the response to resistance training
-
Menon MK, Houchen L, Singh SJ, Morgan MD, Bradding P, Steiner MC. Inflammatory and satellite cells in the quadriceps of patients with COPD and the response to resistance training. Chest 2012;142: 1134-1142.
-
(2012)
Chest
, vol.142
, pp. 1134-1142
-
-
Menon, M.K.1
Houchen, L.2
Singh, S.J.3
Morgan, M.D.4
Bradding, P.5
Steiner, M.C.6
|