메뉴 건너뛰기




Volumn 45, Issue 6, 2011, Pages 1111-1115

Everything prevents emphysema: Are animal models of cigarette smoke-induced chronic obstructive pulmonary disease any use?

Author keywords

Animal models; Chronic obstructive pulmonary disease; Emphysema; Small airway remodeling

Indexed keywords

ALPHA 1 ANTITRYPSIN; CIGARETTE SMOKE; CLARITHROMYCIN; FLUINDOSTATIN; GELATINASE INHIBITOR; HYALURONIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MMP 12 INHIBITOR; MMP 9 INHIBITOR; MYELOPEROXIDASE INHIBITOR; OXIDOREDUCTASE INHIBITOR; ROFLUMILAST; SIMVASTATIN; UNCLASSIFIED DRUG; ZD 0892;

EID: 82755187146     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0087PS     Document Type: Review
Times cited : (59)

References (68)
  • 6
    • 0036800045 scopus 로고    scopus 로고
    • Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs
    • DOI 10.1164/rccm.200202-098OC
    • Wright JL, Farmer SG, Churg A. Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs. Am J Respir Crit Care Med 2002;166:954-960. (Pubitemid 35193225)
    • (2002) American Journal of Respiratory and Critical Care Medicine , vol.166 , Issue.7 , pp. 954-960
    • Wright, J.L.1    Farmer, S.G.2    Churg, A.3
  • 7
    • 0030823772 scopus 로고    scopus 로고
    • Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
    • DOI 10.1126/science.277.5334.2002
    • Hautamaki R, Kobayashi D, Senior R, Shapiro S. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997;277:2002-2004. (Pubitemid 27449144)
    • (1997) Science , vol.277 , Issue.5334 , pp. 2002-2004
    • Hautamaki, R.D.1    Kobayashi, D.K.2    Senior, R.M.3    Shapiro, S.D.4
  • 9
    • 34547815598 scopus 로고    scopus 로고
    • Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in guinea pigs
    • DOI 10.1136/thx.2006.068353
    • Churg A, Wang R, Wang X, Onnervik PO, Thim K, Wright JL. An MMP-9/-12 inhibitor prevents smoke-induced emphysema and small airway remodeling in guinea pigs. Thorax 2007;62:706-713. (Pubitemid 47235016)
    • (2007) Thorax , vol.62 , Issue.8 , pp. 706-713
    • Churg, A.1    Wang, R.2    Wang, X.3    Onnervik, P.-O.4    Thim, K.5    Wright, J.L.6
  • 18
    • 63349099346 scopus 로고    scopus 로고
    • The role of IL-1β in murine cigarette smoke-induced emphysema and small airway remodeling
    • Churg A, Zhou S, Wang X, Wang R, Wright JL. The role of IL-1β in murine cigarette smoke-induced emphysema and small airway remodeling. Am J Respir Cell Mol Biol 2009;40:482-490.
    • (2009) Am J Respir Cell Mol Biol , vol.40 , pp. 482-490
    • Churg, A.1    Zhou, S.2    Wang, X.3    Wang, R.4    Wright, J.L.5
  • 22
  • 24
    • 77954470662 scopus 로고    scopus 로고
    • Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
    • Yoshida T, Mett I, Bhunia AK, Bowman J, Perez M, Zhang L, Gandjeva A, Zhen L, Chukwueke U, Mao T, et al. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nat Med 2010;16:767-773.
    • (2010) Nat Med , vol.16 , pp. 767-773
    • Yoshida, T.1    Mett, I.2    Bhunia, A.K.3    Bowman, J.4    Perez, M.5    Zhang, L.6    Gandjeva, A.7    Zhen, L.8    Chukwueke, U.9    Mao, T.10
  • 26
    • 17644363337 scopus 로고    scopus 로고
    • Aerosolized hyaluronan limits airspace enlargement in a mouse model of cigarette smoke-induced pulmonary emphysema
    • DOI 10.1080/01902140590918669
    • Cantor JO, Cerreta JM, Ochoa M, Ma S, Chow T, Grunig G, Turino GM. Aerosolized hyaluronan limits airspace enlargement in a mouse model of cigarette smoke-induced pulmonary emphysema. Exp Lung Res 2005;31:417-430. (Pubitemid 40563306)
    • (2005) Experimental Lung Research , vol.31 , Issue.4 , pp. 417-430
    • Cantor, J.O.1    Cerreta, J.M.2    Ochoa, M.3    Ma, S.4    Chow, T.5    Grunig, G.6    Turino, G.M.7
  • 28
    • 34247604963 scopus 로고    scopus 로고
    • Unexpected failure of anti-tumor necrosis factor therapy in chronic obstructive pulmonary disease
    • DOI 10.1164/rccm.200702-253ED
    • Barnes PJ. Unexpected failure of anit-tumor necrosis factor therapy in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007;175:866-867. (Pubitemid 46684694)
    • (2007) American Journal of Respiratory and Critical Care Medicine , vol.175 , Issue.9 , pp. 866-867
    • Barnes, P.J.1
  • 30
    • 77958005826 scopus 로고    scopus 로고
    • Roflumilast for the treatment of chronic obstructive pulmonary disease
    • Rabe KF. Roflumilast for the treatment of chronic obstructive pulmonary disease. Expert Rev Respir Med 2010;4:543-555.
    • (2010) Expert Rev Respir Med , vol.4 , pp. 543-555
    • Rabe, K.F.1
  • 31
    • 69149098943 scopus 로고    scopus 로고
    • M2-127 and M2-128 study groups. Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: Two randomised clinical trials
    • Fabbri LM, Calverley PM, Izquierdo-Alonso JL, Bundschuh DS, Brose M, Martinez FJ, Rabe KF. M2-127 and M2-128 study groups. Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet 2009;374:695-703.
    • (2009) Lancet , vol.374 , pp. 695-703
    • Fabbri, L.M.1    Calverley, P.M.2    Izquierdo-Alonso, J.L.3    Bundschuh, D.S.4    Brose, M.5    Martinez, F.J.6    Rabe, K.F.7
  • 34
    • 77956689733 scopus 로고    scopus 로고
    • Susceptibility to exacerbation in chronic obstructive pulmonary disease
    • Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators
    • Hurst JR, Vestbo J, Anzueto A, Locantore N, Müllerova H, Tal-Singer R, Miller B, Lomas DA, Agusti A, Macnee W, et al.; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med 2010;363:1128-1138.
    • (2010) N Engl J Med , vol.363 , pp. 1128-1138
    • Hurst, J.R.1    Vestbo, J.2    Anzueto, A.3    Locantore, N.4    Müllerova, H.5    Tal-Singer, R.6    Miller, B.7    Lomas, D.A.8    Agusti, A.9    Macnee, W.10
  • 35
    • 49049115995 scopus 로고    scopus 로고
    • Animal models of chronic obstructive pulmonary disease
    • Wright JL, Cosio M, Churg A. Animal models of chronic obstructive pulmonary disease. Am J Physiol 2008;295:L1-L5.
    • (2008) Am J Physiol , vol.295
    • Wright, J.L.1    Cosio, M.2    Churg, A.3
  • 37
    • 34748902878 scopus 로고    scopus 로고
    • The effect of smoking cessation and steroid treatment on emphysema in guinea pigs
    • DOI 10.1016/j.rmed.2007.06.022, PII S0954611107002740
    • Milot J, Meshi B, Taher Shabani Rad M, Holding G, Mortazavi N, Hayashi S, Hogg JC. The effect of smoking cessation and steroid treatment on emphysema in guinea pigs. Respir Med 2007;101:2327-2335. (Pubitemid 47471405)
    • (2007) Respiratory Medicine , vol.101 , Issue.11 , pp. 2327-2335
    • Milot, J.1    Meshi, B.2    Taher, S.R.M.3    Holding, G.4    Mortazavi, N.5    Hayashi, S.6    Hogg, J.C.7
  • 38
    • 0036845628 scopus 로고    scopus 로고
    • Smoking cessation decreases the number of metaplastic secretory cells in the small airways of the guinea pig
    • Wright JL, Churg A. Smoking cessation decreases the number of metaplastic secretory cells in the small airways of the guinea pig. Inhal Toxicol 2002;14:101-107.
    • (2002) Inhal Toxicol , vol.14 , pp. 101-107
    • Wright, J.L.1    Churg, A.2
  • 39
    • 0028322034 scopus 로고
    • Effect of smoking cessation on pulmonary and cardiovascular function and structure: Analysis of guinea pig model
    • Wright JL, Sun J-P. The effect of smoking cessation on pulmonary and cardiovascular function and structure. J Appl Physiol 1994;76:2163-2168. (Pubitemid 24158652)
    • (1994) Journal of Applied Physiology , vol.76 , Issue.5 , pp. 2163-2168
    • Wright, J.L.1    Sun, J.-P.2
  • 41
    • 1642462975 scopus 로고    scopus 로고
    • Effects of cigarette smoke exposure and cessation on inflammatory cells and matrix metalloproteinase activity in mice
    • DOI 10.1080/01902140490252858
    • Seagrave JC, Barr EB, March TH. Effects of cigarette smoke exposure and cessation on inflammatory cells and matrix metalloproteinase activity in mice. Exp Lung Res 2004;30:1-15. (Pubitemid 38117522)
    • (2004) Experimental Lung Research , vol.30 , Issue.1 , pp. 1-15
    • Seagrave, J.1    Barr, E.B.2    March, T.H.3    Nikula, K.J.4
  • 42
    • 71849094775 scopus 로고    scopus 로고
    • Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema
    • Motz GT, Eppert BL, Sun G, Wesselkamper SC, Linke MJ, Deka R, Borchers MT. Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema. J Immunol 2008;181:8036-8043.
    • (2008) J Immunol , vol.181 , pp. 8036-8043
    • Motz, G.T.1    Eppert, B.L.2    Sun, G.3    Wesselkamper, S.C.4    Linke, M.J.5    Deka, R.6    Borchers, M.T.7
  • 43
    • 77956698524 scopus 로고    scopus 로고
    • Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation
    • Braber S, Henricks PAJ, Nijkamp FP, Kraneveld AD, Folkerts G. Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation. Respir Res 2010;11:99-111.
    • (2010) Respir Res , vol.11 , pp. 99-111
    • Braber, S.1    Henricks, P.A.J.2    Nijkamp, F.P.3    Kraneveld, A.D.4    Folkerts, G.5
  • 49
    • 79957900741 scopus 로고    scopus 로고
    • Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease
    • Yao H, Rahman I. Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease. Toxicol Appl Pharmacol 2011;254:72-85.
    • (2011) Toxicol Appl Pharmacol , vol.254 , pp. 72-85
    • Yao, H.1    Rahman, I.2
  • 50
    • 0037435009 scopus 로고    scopus 로고
    • Loss of integrin αvbeta6-mediated TGF-beta activation causes Mmp 12-dependent emphysema
    • DOI 10.1038/nature01413
    • Morris DG, Huang X, Kaminski N, Wang Y, Shapiro SD, Dolganov G, Glick A, Sheppard D. Loss of integrin αvβ6-mediated TGF-β activation causes MMP-12-dependent emphysema. Nature 2003;422:169-173. (Pubitemid 36362749)
    • (2003) Nature , vol.422 , Issue.6928 , pp. 169-173
    • Morris, D.G.1    Huang, X.2    Kaminski, N.3    Wang, Y.4    Shapiro, S.D.5    Dolganov, G.6    Gllck, A.7    Sheppard, D.8
  • 52
    • 33645102517 scopus 로고    scopus 로고
    • Alveolar macrophages and emphysema in surfactant protein-D-deficient mice
    • Yoshida M, Whitsett JA. Alveolar macrophages and emphysema in surfactant protein-D-deficient mice. Respirology 2006;11:S37-S40.
    • (2006) Respirology , vol.11
    • Yoshida, M.1    Whitsett, J.A.2
  • 53
    • 74949088495 scopus 로고    scopus 로고
    • Targeted disruption of NF-κB (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: A critical role of p50 in chromatin remodeling
    • Rajendrasozhan S, Chung S, Sundar IK, Yao H, Rahman I. Targeted disruption of NF-κB (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling. Am J Physiol Lung Cell Mol Physiol 2010;298:L197-L209.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298
    • Rajendrasozhan, S.1    Chung, S.2    Sundar, I.K.3    Yao, H.4    Rahman, I.5
  • 58
    • 79551591691 scopus 로고    scopus 로고
    • Pharmacological characterisation of anti-inflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation
    • Wan WY, Morris A, Kinnear G, Pearce W, Mok J, Wyss D, Stevenson CS. Pharmacological characterisation of anti-inflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation. Respir Res 2010;11:126.
    • (2010) Respir Res , vol.11 , pp. 126
    • Wan, W.Y.1    Morris, A.2    Kinnear, G.3    Pearce, W.4    Mok, J.5    Wyss, D.6    Stevenson, C.S.7
  • 60
    • 79952283285 scopus 로고    scopus 로고
    • Therapeutic effects of hyaluronan on smoke-induced elastic fiber injury: Does delayed treatment affect efficacy?
    • Cantor JO, Cerreta JM, Ochoa M, Ma S, Liu M, Turino GM. Therapeutic effects of hyaluronan on smoke-induced elastic fiber injury: does delayed treatment affect efficacy? Lung 2011;189:51-56.
    • (2011) Lung , vol.189 , pp. 51-56
    • Cantor, J.O.1    Cerreta, J.M.2    Ochoa, M.3    Ma, S.4    Liu, M.5    Turino, G.M.6
  • 61
    • 59349084488 scopus 로고    scopus 로고
    • Role of HDAC2 in the pathophysiology of COPD
    • Barnes PJ. Role of HDAC2 in the pathophysiology of COPD. Annu Rev Physiol 2009;71:451-464.
    • (2009) Annu Rev Physiol , vol.71 , pp. 451-464
    • Barnes, P.J.1
  • 62
    • 33751213597 scopus 로고    scopus 로고
    • Cigarette smoke inhibits alveolar repair: A mechanism for the development of emphysema
    • DOI 10.1513/pats.200605-121SF
    • Rennard SI, Togo S, Holz O. Cigarette smoke inhibits alveolar repair: a mechanism for the development of emphysema. Proc Am Thorac Soc 2006;3:703-708. (Pubitemid 44788228)
    • (2006) Proceedings of the American Thoracic Society , vol.3 , Issue.8 , pp. 703-708
    • Rennard, S.I.1    Togo, S.2    Holz, O.3
  • 63
    • 34447556991 scopus 로고    scopus 로고
    • Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease
    • DOI 10.1152/physrev.00048.2006
    • Yoshida T, Tuder RM. Pathobiology of chronic obstructive pulmonary disease. Physiol Rev 2007;87:1047-1082. (Pubitemid 47084676)
    • (2007) Physiological Reviews , vol.87 , Issue.3 , pp. 1047-1082
    • Yoshida, T.1    Tuder, R.M.2
  • 64
    • 58249099942 scopus 로고    scopus 로고
    • COPD as a disease of accelerated lung aging
    • Ito K, Barnes PJ. COPD as a disease of accelerated lung aging. Chest 2009;135:173-180.
    • (2009) Chest , vol.135 , pp. 173-180
    • Ito, K.1    Barnes, P.J.2
  • 65
    • 66649127821 scopus 로고    scopus 로고
    • Immunologic aspects of chronic obstructive pulmonary disease
    • Cosio MG, Saetta M, Agusti A. Immunologic aspects of chronic obstructive pulmonary disease. N Engl J Med 2009;360:2445-2454.
    • (2009) N Engl J Med , vol.360 , pp. 2445-2454
    • Cosio, M.G.1    Saetta, M.2    Agusti, A.3
  • 67
    • 77956797685 scopus 로고    scopus 로고
    • Treatment of COPD: The sooner the better?
    • Decramer M, Cooper CB. Treatment of COPD: the sooner the better? Thorax 2010;65:837-841.
    • (2010) Thorax , vol.65 , pp. 837-841
    • Decramer, M.1    Cooper, C.B.2
  • 68
    • 74849104954 scopus 로고    scopus 로고
    • What drives the peripheral lung-remodeling process in chronic obstructive pulmonary disease?
    • Hogg JC, McDonough JE, Gosselink JV, Hayashi S. What drives the peripheral lung-remodeling process in chronic obstructive pulmonary disease? Proc Am Thorac Soc 2009;6:668-672.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 668-672
    • Hogg, J.C.1    McDonough, J.E.2    Gosselink, J.V.3    Hayashi, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.