Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD

Thorax

Volumn 59, Issue 10, 2004, Pages 837-842

  O'Donnell, R A ^a   Peebles, C ^a   Ward, J A ^a   Daraker, A ^a   Angco, G ^a   Broberg, P ^b   Pierrou, S ^b   Lund, J ^b   Holgate, S T ^a   Davies, D E ^a   Delany, D J ^a   Wilson, S J ^a   Djukanovic, R ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AIRWAY OBSTRUCTION; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE CLASSIFICATION; DISEASE SEVERITY; EMPHYSEMA; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; INFLAMMATION; LEUKOCYTE COUNT; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MEASUREMENT; NEUTROPHIL; NEUTROPHILIA; PRIORITY JOURNAL; SMOKING; BRONCHITIS; COMPUTER ASSISTED TOMOGRAPHY; FORCED EXPIRATORY VOLUME; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RADIOGRAPHY; VITAL CAPACITY;

AIRWAY OBSTRUCTION; BRONCHITIS; FORCED EXPIRATORY VOLUME; HUMANS; LEUKOCYTE COUNT; MIDDLE AGED; NEUTROPHILS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TOMOGRAPHY, X-RAY COMPUTED; VITAL CAPACITY;

EID: 6344267160     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.2003.019349     Document Type: Article

References (34)

1. Cosio M, Ghezzo H, Hogg JC, et al. The relations between structural changes in small airways and pulmonary function tests. N Engl J Med 1978;298:1277-81.
2. Hale KA, Ewing SL, Gosnell BA, et al. Lung disease in long-term cigarette smokers with and without chronic air-flow obstruction. Am Rev Respir Dis 1984;130:716-21.
3. Finkelstein R, Fraser RS, Ghezzo H, et al. Alveolar inflammation and its relation to emphysema in smokers. Am J Respir Crit Care Med 1995;152:1666-72.
4. Leopold JG, Gough J. The centrilobular form of hypertrophic emphysema and its relation to chronic bronchitis. Thorax 1957;12:219-35.
5. Cosio MG, Hale KA, Niewoehner DE. Morphologic and morphometric effects of prolonged cigarette smoking on the small airways. Am Rev Respir Dis 1980;122:265-71.
6. Retamales I, Elliott WM, Meshi B, et al. Amplification of inflammation in emphysema and its association with latent adenoviral infection. Am J Respir Crit Care Med 2001;164:469-73.
7. Turato G, Zuin R, Miniati M, et al. Airway inflammation in severe chronic obstructive pulmonary disease: relationship with lung function and radiologic emphysema. Am J Respir Crit Care Med 2002;166:105-10.
8. Gevenois PA, De Vuyst P, Sy M, et al. Pulmonary emphysema: quantitative CT during expiration. Radiology 1996;199:825-9.
9. Gevenois PA, de Maertelaer V, De Vuyst P, et al. Comparison of computed density and macroscopic morphometry in pulmonary emphysema. Am J Respir Crit Care Med 1995;152:653-7.
10. Keatings VM, Collins PD, Scott DM, et al. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996;153:530-4.
11. Saetta M, Turato G, Facchini FM, et al. Inflammatory cells in the bronchial glands of smokers with chronic bronchitis. Am J Respir Crit Care Med 1997;156:1633-9.
12. 1. Am J Respir Crit Care Med 1997;155:852-7.
13. Knudson RJ, Standen JR, Kaltenborn WT, et al. Expiratory computed tomography for assessment of suspected pulmonary emphysema. Chest 1991;99:1357-66.
14. Soejima K, Yamaguchi K, Kohda E, et al. Longitudinal follow-up study of smoking-induced lung density changes by high-resolution computed tomography. Am J Respir Crit Care Med 2000;161:1264-73.
15. Eda S, Kubo K, Fujimoto K, et al. The relations between expiratory chest CT using helical CT and pulmonary function tests in emphysema. Am J Respir Crit Care Med 1997;155:1290-4.
16. Kubo K, Eda S, Yamamoto H, et al. Expiratory and inspiratory chest computed tomography and pulmonary function tests in cigarette smokers. Eur Respir J 1999;13:252-6.
17. Miniati M, Filippi E, Falaschi F, et al. Radiologic evaluation of emphysema in patients with chronic obstructive pulmonary disease. Chest radiography versus high resolution computed tomography. Am J Respir Crit Care Med 1995;151:1359-67.
18. American Thoracic Society. Standardization of spirometry - 1987 update. Am Rev Respir Dis 1987;136:1285-98.
19. Djukanovic R, Wilson JW, Lai CK, et al. The safely aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma. Am Rev Respir Dis 1991;143:772-7.
20. Pauwels RA, Buist AS, Ma P, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: National Heart, Lung, and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD): executive summary. Respiratory Care 2001;46:798-825.
21. Louis R, Lau LC, Bron AO, et al. The relationship between airways inflammation and asthma severity. Am J Respir Crit Care Med 2000;161:9-16.
22. Holm S. A simple sequentially rejective multiple test procedure. Scand J Stat 1979;6:65-70.
23. Peleman RA, Rytila PH, Kips JC, et al. The cellular composition of induced sputum in chronic obstructive pulmonary disease. Eur Respir J 1999;13:839-43.
24. Muller NL, Staples CA, Miller RR, et al. "Density mask". An objective method to quantitate emphysema using computed tomography. Chest 1988;94:782-7.
25. Gelb AF, Schein M, Kuei J, et al. Limited contribution of emphysema in advanced chronic obstructive pulmonary disease. Am Rev Respir Dis 1993;147:1157-61.
26. Gelb AF, Hogg JC, Muller NL, et al. Contribution of emphysema and small airways in COPD. Chest 1996;109:353-9.
27. Arakawa H, Webb WR. Expiratory high-resolution CT scan. Radiol Clin North Am 1998;36:189-209.
28. Kubo K, Eda S, Yamamoto H, et al. Expiratory and inspiratory chest computed tomography and pulmonary function tests in cigarette smokers. Eur Respir J 1999;13:252-6.
29. Miller RR, Muller NL, Vedal S, et al. Limitations of computed tomography in the assessment of emphysema. Am Rev Respir Dis 1989;139:980-3.
30. Saetta M, Ghezzo H, Kim WD, et al. Loss or alveolar attachments in smokers. A morphometric correlate of lung function impairment. Am Rev Respir Dis 1985;132:894-900.
31. Pare PD, Brooks LA, Bates J, et al. Exponential analysis of the lung pressure-volume curve as a predictor of pulmonary emphysema. Am Rev Respir Dis 1982;126:54-61.
32. Keatings VM, Jatakanon A, Worsdell YM, et al. Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. Am J Respir Crit Care Med 1997;155:542-8.
33. Rutgers SR, Postma DS, ten Hacken NH, et al. Ongoing airway inflammation in patients with COPD who do not currently smoke. Thorax 2000;55:12-8.
34. Betsuyaku T, Nishimura M, Takeyabu K, et al. Neutrophil granule proteins in bronchoalveolar lavage fluid from subjects with subclinical emphysema. Am J Respir Crit Care Med 1999;159:1985-91.