Hypoxia sensitization of hepatocytes to neutrophil elastase-mediated cell death depends on MAPKs and HIF-1α

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 302, Issue 7, 2012, Pages

  Sparkenbaugh, Erica M ^a   Ganey, Patricia E ^a   Roth, Robert A ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Bcl 2 adenovirus E1B interacting protein 3; Inflammation; Liver injury; Necrosis

Indexed keywords

ALPHA TOCOPHEROL; AROMATIC HYDROCARBON RECEPTOR; HETERODIMER; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LAMIN; LEUKOCYTE ELASTASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BNIP3; TUBULIN;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL DEATH; CELL HYPOXIA; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DIMERIZATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; GENE EXPRESSION; GENETIC TRANSCRIPTION; LEUKOCYTE ACTIVATION; LIPID PEROXIDATION; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; SENSITIZATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL DEATH; CELLS, CULTURED; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LEUKOCYTE ELASTASE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; OXYGEN; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84859469853     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00409.2011     Document Type: Article

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