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Volumn 25, Issue 3, 2013, Pages 366-372

Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; CD134 ANTIGEN; CD28 ANTIGEN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INDUCIBLE T CELL COSTIMULATOR; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 12; INTERLEUKIN 21; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; JANUS KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 6; PROTEIN KINASE B; SHORT HAIRPIN RNA; STAT1 PROTEIN; STAT3 PROTEIN; STAT4 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR MAF; TRANSCRIPTION FACTOR T BET;

EID: 84879221506     PISSN: 09527915     EISSN: 18790372     Source Type: Journal    
DOI: 10.1016/j.coi.2013.04.003     Document Type: Review
Times cited : (84)

References (64)
  • 1
    • 0035969773 scopus 로고    scopus 로고
    • Integrating historical, clinical and molecular genetic data in order to explain the origin and virulence of the 1918 Spanish influenza virus
    • Taubenberger J.K., Reid A.H., Janczewski T.A., Fanning T.G. Integrating historical, clinical and molecular genetic data in order to explain the origin and virulence of the 1918 Spanish influenza virus. Philos Trans R Soc Lond Ser B: Biol Sci 2001, 356:1829-1839.
    • (2001) Philos Trans R Soc Lond Ser B: Biol Sci , vol.356 , pp. 1829-1839
    • Taubenberger, J.K.1    Reid, A.H.2    Janczewski, T.A.3    Fanning, T.G.4
  • 3
    • 84862641275 scopus 로고    scopus 로고
    • HIV vaccine design: the neutralizing antibody conundrum
    • Stamatatos L. HIV vaccine design: the neutralizing antibody conundrum. Curr Opin Immunol 2012, 24:316-323.
    • (2012) Curr Opin Immunol , vol.24 , pp. 316-323
    • Stamatatos, L.1
  • 5
    • 0021040439 scopus 로고
    • The smallpox story: life and death of an old disease
    • Behbehani A.M. The smallpox story: life and death of an old disease. Microbiol Rev 1983, 47:455-509.
    • (1983) Microbiol Rev , vol.47 , pp. 455-509
    • Behbehani, A.M.1
  • 6
    • 33745068410 scopus 로고    scopus 로고
    • Immunity and immunological memory following smallpox vaccination
    • Amanna I.J., Slifka M.K., Crotty S. Immunity and immunological memory following smallpox vaccination. Immunol Rev 2006, 211:320-337.
    • (2006) Immunol Rev , vol.211 , pp. 320-337
    • Amanna, I.J.1    Slifka, M.K.2    Crotty, S.3
  • 8
  • 9
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu M., Kinoshita K., Fagarasan S., Yamada S., Shinkai Y., Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 2000, 102:553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 10
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S. Follicular helper CD4 T cells (TFH). Annu Rev Immunol 2011, 29:621-663.
    • (2011) Annu Rev Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 14
    • 0036889996 scopus 로고    scopus 로고
    • The two faces of IL-6 on Th1/Th2 differentiation
    • Diehl S., Rincon M. The two faces of IL-6 on Th1/Th2 differentiation. Mol Immunol 2002, 39:531-536.
    • (2002) Mol Immunol , vol.39 , pp. 531-536
    • Diehl, S.1    Rincon, M.2
  • 15
    • 84875417243 scopus 로고    scopus 로고
    • Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation
    • Choi Y.S., Eto D., Yang J.A., Lao C., Crotty S. Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation. J Immunol 2013, 190:3049-3053.
    • (2013) J Immunol , vol.190 , pp. 3049-3053
    • Choi, Y.S.1    Eto, D.2    Yang, J.A.3    Lao, C.4    Crotty, S.5
  • 16
  • 17
    • 46749151286 scopus 로고    scopus 로고
    • Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
    • Nurieva R.I., Chung Y., Hwang D., Yang X.O., Kang H.S., Ma L., Wang Y-H., Watowich S.S., Jetten A.M., Tian Q., et al. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 2008, 29:138-149.
    • (2008) Immunity , vol.29 , pp. 138-149
    • Nurieva, R.I.1    Chung, Y.2    Hwang, D.3    Yang, X.O.4    Kang, H.S.5    Ma, L.6    Wang, Y.-H.7    Watowich, S.S.8    Jetten, A.M.9    Tian, Q.10
  • 18
    • 67649229170 scopus 로고    scopus 로고
    • The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals
    • Hotson A.N., Hardy J.W., Hale M.B., Contag C.H., Nolan G.P. The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals. J Immunol 2009, 182:7558-7568.
    • (2009) J Immunol , vol.182 , pp. 7558-7568
    • Hotson, A.N.1    Hardy, J.W.2    Hale, M.B.3    Contag, C.H.4    Nolan, G.P.5
  • 21
    • 79956085895 scopus 로고    scopus 로고
    • Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages
    • Liao W., Lin J-X., Wang L., Li P., Leonard W.J. Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat Immunol 2011, 12:551-559.
    • (2011) Nat Immunol , vol.12 , pp. 551-559
    • Liao, W.1    Lin, J.-X.2    Wang, L.3    Li, P.4    Leonard, W.J.5
  • 22
    • 79952637807 scopus 로고    scopus 로고
    • IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation
    • Eto D., Lao C., Ditoro D., Barnett B., Escobar T.C., Kageyama R., Yusuf I., Crotty S. IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. PLoS ONE 2011, 6:e17739.
    • (2011) PLoS ONE , vol.6
    • Eto, D.1    Lao, C.2    Ditoro, D.3    Barnett, B.4    Escobar, T.C.5    Kageyama, R.6    Yusuf, I.7    Crotty, S.8
  • 23
    • 84870283741 scopus 로고    scopus 로고
    • B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1
    • Karnowski A., Chevrier S., Belz G.T., Mount A., Emslie D., D'Costa K., Tarlinton D.M., Kallies A., Corcoran L.M. B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. J Exp Med 2012, 209:2049-2064.
    • (2012) J Exp Med , vol.209 , pp. 2049-2064
    • Karnowski, A.1    Chevrier, S.2    Belz, G.T.3    Mount, A.4    Emslie, D.5    D'Costa, K.6    Tarlinton, D.M.7    Kallies, A.8    Corcoran, L.M.9
  • 25
    • 84859708611 scopus 로고    scopus 로고
    • The 1-1-1 fallacy
    • Crotty S. The 1-1-1 fallacy. Immunol Rev 2012, 247:133-142.
    • (2012) Immunol Rev , vol.247 , pp. 133-142
    • Crotty, S.1
  • 27
    • 0035400054 scopus 로고    scopus 로고
    • Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex
    • Asao H., Okuyama C., Kumaki S., Ishii N., Tsuchiya S., Foster D., Sugamura K. Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. J Immunol 2001, 167:1-5.
    • (2001) J Immunol , vol.167 , pp. 1-5
    • Asao, H.1    Okuyama, C.2    Kumaki, S.3    Ishii, N.4    Tsuchiya, S.5    Foster, D.6    Sugamura, K.7
  • 29
    • 79959328032 scopus 로고    scopus 로고
    • ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
    • Choi Y.S., Kageyama R., Eto D., Escobar T.C., Johnston R.J., Monticelli L., Lao C., Crotty S. ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity 2011, 34:932-946.
    • (2011) Immunity , vol.34 , pp. 932-946
    • Choi, Y.S.1    Kageyama, R.2    Eto, D.3    Escobar, T.C.4    Johnston, R.J.5    Monticelli, L.6    Lao, C.7    Crotty, S.8
  • 30
    • 80051618656 scopus 로고    scopus 로고
    • Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation
    • Goenka R., Barnett L.G., Silver J.S., O'Neill P.J., Hunter C.A., Cancro M.P., Laufer T.M. Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation. J Immunol 2011, 187:1091-1095.
    • (2011) J Immunol , vol.187 , pp. 1091-1095
    • Goenka, R.1    Barnett, L.G.2    Silver, J.S.3    O'Neill, P.J.4    Hunter, C.A.5    Cancro, M.P.6    Laufer, T.M.7
  • 34
    • 84869213212 scopus 로고    scopus 로고
    • Interferon-γ excess leads to pathogenic accumulation of follicular helper T cells and germinal centers
    • Lee S.K., Silva D.G., Martin J.L., Pratama A., Hu X., Chang P-P., Walters G., Vinuesa C.G. Interferon-γ excess leads to pathogenic accumulation of follicular helper T cells and germinal centers. Immunity 2012, 37:880-892.
    • (2012) Immunity , vol.37 , pp. 880-892
    • Lee, S.K.1    Silva, D.G.2    Martin, J.L.3    Pratama, A.4    Hu, X.5    Chang, P.-P.6    Walters, G.7    Vinuesa, C.G.8
  • 36
    • 84859972127 scopus 로고    scopus 로고
    • JAK and STAT signaling molecules in immunoregulation and immune-mediated disease
    • O'Shea J.J., Plenge R. JAK and STAT signaling molecules in immunoregulation and immune-mediated disease. Immunity 2012, 36:542-550.
    • (2012) Immunity , vol.36 , pp. 542-550
    • O'Shea, J.J.1    Plenge, R.2
  • 37
    • 73949090666 scopus 로고    scopus 로고
    • Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase
    • Gigoux M., Shang J., Pak Y., Xu M., Choe J., Mak T.W., Suh W-K. Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase. Proc Natl Acad Sci U S A 2009, 106:20371-20376.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 20371-20376
    • Gigoux, M.1    Shang, J.2    Pak, Y.3    Xu, M.4    Choe, J.5    Mak, T.W.6    Suh, W.-K.7
  • 38
    • 79961233459 scopus 로고    scopus 로고
    • Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development
    • Hu H., Wu X., Jin W., Chang M., Cheng X., Sun S-C. Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development. Proc Natl Acad Sci U S A 2011, 108:12827-12832.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 12827-12832
    • Hu, H.1    Wu, X.2    Jin, W.3    Chang, M.4    Cheng, X.5    Sun, S.-C.6
  • 40
    • 79953185367 scopus 로고    scopus 로고
    • OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling
    • So T., Choi H., Croft M. OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling. J Immunol 2011, 186:3547-3555.
    • (2011) J Immunol , vol.186 , pp. 3547-3555
    • So, T.1    Choi, H.2    Croft, M.3
  • 41
    • 0142259712 scopus 로고    scopus 로고
    • Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
    • Rudd C.E., Schneider H. Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling. Nat Rev Immunol 2003, 3:544-556.
    • (2003) Nat Rev Immunol , vol.3 , pp. 544-556
    • Rudd, C.E.1    Schneider, H.2
  • 42
    • 79956081339 scopus 로고    scopus 로고
    • The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells
    • Ise W., Kohyama M., Schraml B.U., Zhang T., Schwer B., Basu U., Alt F.W., Tang J., Oltz E.M., Murphy T.L., et al. The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells. Nat Immunol 2011, 12:536-543.
    • (2011) Nat Immunol , vol.12 , pp. 536-543
    • Ise, W.1    Kohyama, M.2    Schraml, B.U.3    Zhang, T.4    Schwer, B.5    Basu, U.6    Alt, F.W.7    Tang, J.8    Oltz, E.M.9    Murphy, T.L.10
  • 43
    • 58449124804 scopus 로고    scopus 로고
    • The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
    • Bauquet A.T., Jin H., Paterson A.M., Mitsdoerffer M., Ho I-C., Sharpe A.H., Kuchroo V.K. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol 2009, 10:167-175.
    • (2009) Nat Immunol , vol.10 , pp. 167-175
    • Bauquet, A.T.1    Jin, H.2    Paterson, A.M.3    Mitsdoerffer, M.4    Ho, I.-C.5    Sharpe, A.H.6    Kuchroo, V.K.7
  • 44
    • 84859711533 scopus 로고    scopus 로고
    • Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation
    • Kroenke M.A., Eto D., Locci M., Cho M., Davidson T., Haddad E.K., Crotty S. Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J Immunol 2012, 188:3734-3744.
    • (2012) J Immunol , vol.188 , pp. 3734-3744
    • Kroenke, M.A.1    Eto, D.2    Locci, M.3    Cho, M.4    Davidson, T.5    Haddad, E.K.6    Crotty, S.7
  • 47
    • 84873531162 scopus 로고    scopus 로고
    • Harnessing CD4(+) T cell responses in HIV vaccine development
    • Streeck H., D'Souza M.P., Littman D.R., Crotty S. Harnessing CD4(+) T cell responses in HIV vaccine development. Nat Med 2013, 19:143-149.
    • (2013) Nat Med , vol.19 , pp. 143-149
    • Streeck, H.1    D'Souza, M.P.2    Littman, D.R.3    Crotty, S.4
  • 48
    • 80755172184 scopus 로고    scopus 로고
    • Opposing signals from the bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells
    • Pepper M., Pagán A.J., Igyártó B.Z., Taylor J.J., Jenkins M.K. Opposing signals from the bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity 2011, 35:583-595.
    • (2011) Immunity , vol.35 , pp. 583-595
    • Pepper, M.1    Pagán, A.J.2    Igyártó, B.Z.3    Taylor, J.J.4    Jenkins, M.K.5
  • 49
    • 84875444198 scopus 로고    scopus 로고
    • Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory
    • Choi Y.S., Yang J.A., Yusuf I., Johnston R.J., Greenbaum J., Peters B., Crotty S. Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory. J Immunol 2013, 190:4014-4026.
    • (2013) J Immunol , vol.190 , pp. 4014-4026
    • Choi, Y.S.1    Yang, J.A.2    Yusuf, I.3    Johnston, R.J.4    Greenbaum, J.5    Peters, B.6    Crotty, S.7
  • 50
    • 0028819828 scopus 로고
    • Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes
    • Gilmour K.C., Pine R., Reich N.C. Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes. Proc Natl Acad Sci U S A 1995, 92:10772-10776.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 10772-10776
    • Gilmour, K.C.1    Pine, R.2    Reich, N.C.3
  • 51
    • 33845958028 scopus 로고    scopus 로고
    • Cytokine-dependent Blimp-1 expression in activated T cells inhibits IL-2 production
    • Gong D., Malek T.R. Cytokine-dependent Blimp-1 expression in activated T cells inhibits IL-2 production. J Immunol 2007, 178:242-252.
    • (2007) J Immunol , vol.178 , pp. 242-252
    • Gong, D.1    Malek, T.R.2
  • 52
    • 84863116170 scopus 로고    scopus 로고
    • STAT5 is a potent negative regulator of TFH cell differentiation
    • Johnston R.J., Choi Y.S., Diamond J.A., Yang J.A., Crotty S. STAT5 is a potent negative regulator of TFH cell differentiation. J Exp Med 2012, 209:243-250.
    • (2012) J Exp Med , vol.209 , pp. 243-250
    • Johnston, R.J.1    Choi, Y.S.2    Diamond, J.A.3    Yang, J.A.4    Crotty, S.5
  • 53
    • 84858706847 scopus 로고    scopus 로고
    • Molecular mechanisms that control the expression and activity of Bcl-6 in T(H)1 cells to regulate flexibility with a T(FH)-like gene profile
    • Oestreich K.J., Mohn S.E., Weinmann A.S. Molecular mechanisms that control the expression and activity of Bcl-6 in T(H)1 cells to regulate flexibility with a T(FH)-like gene profile. Nat Immunol 2012, 13:405-411.
    • (2012) Nat Immunol , vol.13 , pp. 405-411
    • Oestreich, K.J.1    Mohn, S.E.2    Weinmann, A.S.3
  • 55
    • 84855868834 scopus 로고    scopus 로고
    • FoxO1, the transcriptional chief of staff of energy metabolism
    • Kousteni S. FoxO1, the transcriptional chief of staff of energy metabolism. Bone 2012, 50:437-443.
    • (2012) Bone , vol.50 , pp. 437-443
    • Kousteni, S.1
  • 59
    • 0036595049 scopus 로고    scopus 로고
    • Suppressors of cytokine signalling (SOCS) in the immune system
    • Alexander W.S. Suppressors of cytokine signalling (SOCS) in the immune system. Nat Rev Immunol 2002, 2:410-416.
    • (2002) Nat Rev Immunol , vol.2 , pp. 410-416
    • Alexander, W.S.1
  • 60
    • 0031888837 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells
    • Kim H., Hawley T.S., Hawley R.G., Baumann H. Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells. Mol Cell Biol 1998, 18:1525-1533.
    • (1998) Mol Cell Biol , vol.18 , pp. 1525-1533
    • Kim, H.1    Hawley, T.S.2    Hawley, R.G.3    Baumann, H.4
  • 62
    • 0028943484 scopus 로고
    • Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
    • Jacobson N.G., Szabo S.J., Weber-Nordt R.M., Zhong Z., Schreiber R.D., Darnell J.E., Murphy K.M. Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp Med 1995, 181:1755-1762.
    • (1995) J Exp Med , vol.181 , pp. 1755-1762
    • Jacobson, N.G.1    Szabo, S.J.2    Weber-Nordt, R.M.3    Zhong, Z.4    Schreiber, R.D.5    Darnell, J.E.6    Murphy, K.M.7


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