6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ)

Cancer Letters

Volumn 336, Issue 1, 2013, Pages 127-139

  Tan, Boon Shing ^a   Kang, Owen ^a   Mai, Chun Wai ^a   Tiong, Kai Hung ^a   Khoo, Alan Soo Beng ^b   Pichika, Mallikarjuna Rao ^a   Bradshaw, Tracey D ^c   Leong, Chee Onn ^a  

^a INTERNATIONAL MEDICAL UNIVERSITY   (Malaysia)

^b INSTITUTE FOR MEDICAL RESEARCH   (Malaysia)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

6 Shogaol; Breast cancer; Colon cancer; NF B; PPAR

Indexed keywords

(6) GINGEROL; 6 SHOGAOL; ANTINEOPLASTIC AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NSC 752389; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL PROLIFERATION; CELL STRAIN HT29; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; EMBRYO; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOSIS INHIBITION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CATECHOLS; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; MCF-7 CELLS; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PPAR GAMMA; PROSTAGLANDIN D2; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 84879001106     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.04.014     Document Type: Article

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