-
1
-
-
11144354423
-
Pathology of ovarian cancers in BRCA1 and BRCA2 carriers
-
Lakhani SR, Manek S, Penault-Llorca F, et al. Pathology of ovarian cancers in BRCA1 and BRCA2 carriers. Clin Cancer Res 2004;10: 2473-81.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2473-2481
-
-
Lakhani, S.R.1
Manek, S.2
Penault-Llorca, F.3
-
2
-
-
0037014795
-
Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers
-
Jazaeri AA, Yee CJ, Sotiriou C, Brantley KR, Boyd J, Liu ET. Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers. J Natl Cancer Inst 2002;94:990-1000.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 990-1000
-
-
Jazaeri, A.A.1
Yee, C.J.2
Sotiriou, C.3
Brantley, K.R.4
Boyd, J.5
Liu, E.T.6
-
3
-
-
0037403380
-
Improved survival in women with BRCA-associated ovarian carcinoma
-
Cass I, Baldwin RL, Varkey T, Moslehi R, Narod SA, Karlan BY. Improved survival in women with BRCA-associated ovarian carcinoma. Cancer 2003;97:2187-95.
-
(2003)
Cancer
, vol.97
, pp. 2187-2195
-
-
Cass, I.1
Baldwin, R.L.2
Varkey, T.3
Moslehi, R.4
Narod, S.A.5
Karlan, B.Y.6
-
4
-
-
37849030476
-
Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: The national Israeli study of ovarian cancer
-
Chetrit A, Hirsh-Yechezkel G, Ben-David Y, Lubin F, Friedman E, Sadetzki S. Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer. J Clin Oncol 2008;26:20-5.
-
(2008)
J Clin Oncol
, vol.26
, pp. 20-25
-
-
Chetrit, A.1
Hirsh-Yechezkel, G.2
Ben-David, Y.3
Lubin, F.4
Friedman, E.5
Sadetzki, S.6
-
5
-
-
0034600109
-
Clinicopathologic features of BRCA-linked and sporadic ovarian cancer
-
Boyd J, Sonoda Y, Federici MG, et al. Clinicopathologic features of BRCA-linked and sporadic ovarian cancer. Jama 2000;283:2260-5.
-
(2000)
Jama
, vol.283
, pp. 2260-2265
-
-
Boyd, J.1
Sonoda, Y.2
Federici, M.G.3
-
6
-
-
9744263911
-
The role of BRCA1 in the cellular response to chemotherapy
-
Kennedy RD, Quinn JE, Mullan PB, Johnston PG, Harkin DP. The role of BRCA1 in the cellular response to chemotherapy. J Natl Cancer Inst 2004;96:1659-68.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1659-1668
-
-
Kennedy, R.D.1
Quinn, J.E.2
Mullan, P.B.3
Johnston, P.G.4
Harkin, D.P.5
-
7
-
-
25144498670
-
The carboxyl-terminal of BRCA1 is required for subnuclear assembly of RAD51 after treatment with cisplatin but not ionizing radiation in human breast and ovarian cancer cells
-
Zhou C, Huang P, Liu J. The carboxyl-terminal of BRCA1 is required for subnuclear assembly of RAD51 after treatment with cisplatin but not ionizing radiation in human breast and ovarian cancer cells. Biochem Biophys Res Commun 2005;336:952-60.
-
(2005)
Biochem Biophys Res Commun
, vol.336
, pp. 952-960
-
-
Zhou, C.1
Huang, P.2
Liu, J.3
-
8
-
-
33749482498
-
A mouse model for the molecular characterization of brca1-associated ovarian carcinoma
-
Xing D, Orsulic S. A mouse model for the molecular characterization of brca1-associated ovarian carcinoma. Cancer Res 2006;66: 8949-53.
-
(2006)
Cancer Res
, vol.66
, pp. 8949-8953
-
-
Xing, D.1
Orsulic, S.2
-
9
-
-
0036463949
-
Induction of ovarian cancer by defined multiple genetic changes in a mouse model system
-
Orsulic S, Li Y, Soslow RA, Vitale-Cross LA, Gutkind JS, Varmus HE. Induction of ovarian cancer by defined multiple genetic changes in a mouse model system. Cancer Cell 2002;1:53-62.
-
(2002)
Cancer Cell
, vol.1
, pp. 53-62
-
-
Orsulic, S.1
Li, Y.2
Soslow, R.A.3
Vitale-Cross, L.A.4
Gutkind, J.S.5
Varmus, H.E.6
-
10
-
-
18744407590
-
A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance
-
Xing D, Orsulic S. A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance. Proc Natl Acad Sci U S A 2005;102: 6936-41.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 6936-6941
-
-
Xing, D.1
Orsulic, S.2
-
11
-
-
0033600234
-
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
-
Gong JG, Costanzo A, Yang HQ, et al. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature 1999;399:806-9.
-
(1999)
Nature
, vol.399
, pp. 806-809
-
-
Gong, J.G.1
Costanzo, A.2
Yang, H.Q.3
-
12
-
-
0041997348
-
Chemosensitivity linked to p73 function
-
Irwin MS, Kondo K, Marin MC, Cheng LS, Hahn WC, Kaelin WG, Jr. Chemosensitivity linked to p73 function. Cancer Cell 2003;3:403-10.
-
(2003)
Cancer Cell
, vol.3
, pp. 403-410
-
-
Irwin, M.S.1
Kondo, K.2
Marin, M.C.3
Cheng, L.S.4
Hahn, W.C.5
Kaelin Jr., W.G.6
-
13
-
-
34248166978
-
The p63/ p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers
-
Leong CO, Vidnovic N, DeYoung MP, Sgroi D, Ellisen LW. The p63/ p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers. J Clin Invest 2007;117: 1370-80.
-
(2007)
J Clin Invest
, vol.117
, pp. 1370-1380
-
-
Leong, C.O.1
Vidnovic, N.2
DeYoung, M.P.3
Sgroi, D.4
Ellisen, L.W.5
-
14
-
-
70350707752
-
The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting
-
Lunghi P, Costanzo A, Mazzera L, Rizzoli V, Levrero M, Bonati A. The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting. Clin Cancer Res 2009;15:6495-502.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6495-6502
-
-
Lunghi, P.1
Costanzo, A.2
Mazzera, L.3
Rizzoli, V.4
Levrero, M.5
Bonati, A.6
-
15
-
-
33846976549
-
Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation
-
DelloRusso C, Welcsh PL, Wang W, Garcia RL, King MC, Swisher EM. Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation. Mol Cancer Res 2007; 5:35-45.
-
(2007)
Mol Cancer Res
, vol.5
, pp. 35-45
-
-
DelloRusso, C.1
Welcsh, P.L.2
Wang, W.3
Garcia, R.L.4
King, M.C.5
Swisher, E.M.6
-
16
-
-
30344450404
-
p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis
-
Rocco JW, Leong CO, Kuperwasser N, DeYoung MP, Ellisen LW. p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis. Cancer Cell 2006;9:45-56.
-
(2006)
Cancer Cell
, vol.9
, pp. 45-56
-
-
Rocco, J.W.1
Leong, C.O.2
Kuperwasser, N.3
DeYoung, M.P.4
Ellisen, L.W.5
-
17
-
-
0030925099
-
Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors
-
Stirzaker C, Millar DS, Paul CL, et al. Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors. Cancer Res 1997;57:2229-37.
-
(1997)
Cancer Res
, vol.57
, pp. 2229-2237
-
-
Stirzaker, C.1
Millar, D.S.2
Paul, C.L.3
-
18
-
-
0036802652
-
An RCAS-TVA-based approach to designer mouse models
-
Orsulic S. An RCAS-TVA-based approach to designer mouse models. Mamm Genome 2002;13:543-7.
-
(2002)
Mamm Genome
, vol.13
, pp. 543-547
-
-
Orsulic, S.1
-
19
-
-
14044251637
-
E1A activates transcription of p73 and Noxa to induce apoptosis
-
Flinterman M, Guelen L, Ezzati-Nik S, et al. E1A activates transcription of p73 and Noxa to induce apoptosis. J Biol Chem 2005;280: 5945-59.
-
(2005)
J Biol Chem
, vol.280
, pp. 5945-5959
-
-
Flinterman, M.1
Guelen, L.2
Ezzati-Nik, S.3
-
20
-
-
1542379662
-
p73 induces apoptosis via PUMA transactivation and Bax mitochondrial translocation
-
Melino G, Bernassola F, Ranalli M, et al. p73 induces apoptosis via PUMA transactivation and Bax mitochondrial translocation. J Biol Chem 2004;279:8076-83.
-
(2004)
J Biol Chem
, vol.279
, pp. 8076-8083
-
-
Melino, G.1
Bernassola, F.2
Ranalli, M.3
-
21
-
-
21044442524
-
The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA damage
-
Strano S, Monti O, Pediconi N, et al. The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA damage. Mol Cell 2005;18:447-59.
-
(2005)
Mol Cell
, vol.18
, pp. 447-459
-
-
Strano, S.1
Monti, O.2
Pediconi, N.3
-
22
-
-
29144506137
-
The Fanconi anemia/BRCA pathway: New faces in the crowd
-
Kennedy RD, D'Andrea AD. The Fanconi anemia/BRCA pathway: new faces in the crowd. Genes Dev 2005;19:2925-40.
-
(2005)
Genes Dev
, vol.19
, pp. 2925-2940
-
-
Kennedy, R.D.1
D'Andrea, A.D.2
-
23
-
-
0038075462
-
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
-
Taniguchi T, Tischkowitz M, Ameziane N, et al. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 2003;9:568-74.
-
(2003)
Nat Med
, vol.9
, pp. 568-574
-
-
Taniguchi, T.1
Tischkowitz, M.2
Ameziane, N.3
-
24
-
-
39149118956
-
Optimal chemotherapy treatment for women with recurrent ovarian cancer
-
Fung-Kee-Fung M, Oliver T, Elit L, Oza A, Hirte HW, Bryson P. Optimal chemotherapy treatment for women with recurrent ovarian cancer. Curr Oncol 2007;14:195-208.
-
(2007)
Curr Oncol
, vol.14
, pp. 195-208
-
-
Fung-Kee-Fung, M.1
Oliver, T.2
Elit, L.3
Oza, A.4
Hirte, H.W.5
Bryson, P.6
-
25
-
-
0033565514
-
Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5¡ä CpG island methylation
-
Corn PG, Kuerbitz SJ, van Noesel MM, et al. Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5¡ä CpG island methylation. Cancer Res 1999;59:3352-6.
-
(1999)
Cancer Res
, vol.59
, pp. 3352-3356
-
-
Corn, P.G.1
Kuerbitz, S.J.2
Van Noesel, M.M.3
-
26
-
-
34548593716
-
Transcriptional regulation of the p73 gene, a member of the p53 family, by early growth response-1 (Egr-1)
-
Lee SW, Kim EJ, Um SJ. Transcriptional regulation of the p73 gene, a member of the p53 family, by early growth response-1 (Egr-1). Biochem Biophys Res Commun 2007;362:1044-50.
-
(2007)
Biochem Biophys Res Commun
, vol.362
, pp. 1044-1050
-
-
Lee, S.W.1
Kim, E.J.2
Um, S.J.3
-
27
-
-
0038142184
-
Differential regulation of E2F1 apoptotic target genes in response to DNA damage
-
Pediconi N, Ianari A, Costanzo A, et al. Differential regulation of E2F1 apoptotic target genes in response to DNA damage. Nat Cell Biol 2003;5:552-8.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 552-558
-
-
Pediconi, N.1
Ianari, A.2
Costanzo, A.3
-
28
-
-
25444485414
-
CpG island methylation of DNA damage response genes in advanced ovarian cancer
-
Teodoridis JM, Hall J, Marsh S, et al. CpG island methylation of DNA damage response genes in advanced ovarian cancer. Cancer Res 2005;65:8961-7.
-
(2005)
Cancer Res
, vol.65
, pp. 8961-8967
-
-
Teodoridis, J.M.1
Hall, J.2
Marsh, S.3
-
29
-
-
27744451460
-
äEF1 repressor controls selectively p53 family members during differentiation
-
Fontemaggi G, Gurtner A, Damalas A, et al. äEF1 repressor controls selectively p53 family members during differentiation. Oncogene 2005;24:7273-80.
-
(2005)
Oncogene
, vol.24
, pp. 7273-7280
-
-
Fontemaggi, G.1
Gurtner, A.2
Damalas, A.3
-
30
-
-
0035193044
-
The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiation
-
Fontemaggi G, Gurtner A, Strano S, et al. The transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiation. Mol Cell Biol 2001;21:8461-70.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8461-8470
-
-
Fontemaggi, G.1
Gurtner, A.2
Strano, S.3
-
31
-
-
34249289041
-
Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
-
Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 2007;7:415-28.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
32
-
-
0033568198
-
New mode of DNA binding of multizinc finger transcription factors: ÄEF1 family members bind with two hands to two target sites
-
Remacle JE, Kraft H, Lerchner W, et al. New mode of DNA binding of multizinc finger transcription factors: äEF1 family members bind with two hands to two target sites. Embo J 1999;18:5073-84.
-
(1999)
Embo J
, vol.18
, pp. 5073-5084
-
-
Remacle, J.E.1
Kraft, H.2
Lerchner, W.3
-
33
-
-
39849097680
-
Resistance to therapy caused by intragenic deletion in BRCA2
-
Edwards SL, Brough R, Lord CJ, et al. Resistance to therapy caused by intragenic deletion in BRCA2. Nature 2008;451:1111-5.
-
(2008)
Nature
, vol.451
, pp. 1111-1115
-
-
Edwards, S.L.1
Brough, R.2
Lord, C.J.3
-
34
-
-
39849106300
-
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
-
Sakai W, Swisher EM, Karlan BY, et al. Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers. Nature 2008;451:1116-20.
-
(2008)
Nature
, vol.451
, pp. 1116-1120
-
-
Sakai, W.1
Swisher, E.M.2
Karlan, B.Y.3
-
35
-
-
42349096328
-
Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance
-
Swisher EM, Sakai W, Karlan BY, Wurz K, Urban N, Taniguchi T. Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance. Cancer Res 2008;68:2581-6.
-
(2008)
Cancer Res
, vol.68
, pp. 2581-2586
-
-
Swisher, E.M.1
Sakai, W.2
Karlan, B.Y.3
Wurz, K.4
Urban, N.5
Taniguchi, T.6
-
36
-
-
0033600240
-
Interaction of c-Abl and p73α and their collaboration to induce apoptosis
-
Agami R, Blandino G, Oren M, Shaul Y. Interaction of c-Abl and p73α and their collaboration to induce apoptosis. Nature 1999;399:809-13.
-
(1999)
Nature
, vol.399
, pp. 809-813
-
-
Agami, R.1
Blandino, G.2
Oren, M.3
Shaul, Y.4
-
37
-
-
0033600235
-
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
-
Yuan ZM, Shioya H, Ishiko T, et al. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature 1999; 399:814-7.
-
(1999)
Nature
, vol.399
, pp. 814-817
-
-
Yuan, Z.M.1
Shioya, H.2
Ishiko, T.3
-
38
-
-
41949088521
-
DNp73 a matter of cancer: Mechanisms and clinical implications
-
Buhlmann S, Putzer BM. DNp73 a matter of cancer: mechanisms and clinical implications. Biochim Biophys Acta 2008;1785:207-16.
-
(2008)
Biochim Biophys Acta
, vol.1785
, pp. 207-216
-
-
Buhlmann, S.1
Putzer, B.M.2
-
39
-
-
28544445114
-
Clinical relevance of dominant-negative p73 isoforms for responsiveness to chemotherapy and survival in ovarian cancer: Evidence for a crucial p53-73 cross-talk in vivo
-
Concin N, Hofstetter G, Berger A, et al. Clinical relevance of dominant-negative p73 isoforms for responsiveness to chemotherapy and survival in ovarian cancer: evidence for a crucial p53-73 cross-talk in vivo. Clin Cancer Res 2005;11:8372-83.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8372-8383
-
-
Concin, N.1
Hofstetter, G.2
Berger, A.3
-
40
-
-
3543110350
-
p63 and p73: Roles in development and tumor formation
-
Moll UM, Slade N. p63 and p73: roles in development and tumor formation. Mol Cancer Res 2004;2:371-86.
-
(2004)
Mol Cancer Res
, vol.2
, pp. 371-386
-
-
Moll, U.M.1
Slade, N.2
-
41
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002;16:6-21.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
42
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A, Mikkelsen TS, Gu H, et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 2008;454: 766-70.
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
-
43
-
-
33646865180
-
Control of developmental regulators by Polycomb in human embryonic stem cells
-
Lee TI, Jenner RG, Boyer LA, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006;125: 301-13.
-
(2006)
Cell
, vol.125
, pp. 301-313
-
-
Lee, T.I.1
Jenner, R.G.2
Boyer, L.A.3
-
44
-
-
34547792388
-
Epigenetic gene silencing in cancer: The DNA hypermethylome
-
Esteller M. Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum Mol Genet 2007;16:R50-9.
-
(2007)
Hum Mol Genet
, vol.16
-
-
Esteller, M.1
-
45
-
-
57649196594
-
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
-
Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 2008;135:1201-12.
-
(2008)
Cell
, vol.135
, pp. 1201-1212
-
-
Rai, K.1
Huggins, I.J.2
James, S.R.3
Karpf, A.R.4
Jones, D.A.5
Cairns, B.R.6
-
46
-
-
34547116841
-
The disappearing Barr body in breast and ovarian cancers
-
Pageau GJ, Hall LL, Ganesan S, Livingston DM, Lawrence JB. The disappearing Barr body in breast and ovarian cancers. Nat Rev Cancer 2007;7:628-33.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 628-633
-
-
Pageau, G.J.1
Hall, L.L.2
Ganesan, S.3
Livingston, D.M.4
Lawrence, J.B.5
-
47
-
-
49249138928
-
Sporadic epithelial ovarian cancer: Clinical relevance of BRCA1 inhibition in the DNA damage and repair pathway
-
Weberpals JI, Clark-Knowles KV, Vanderhyden BC. Sporadic epithelial ovarian cancer: clinical relevance of BRCA1 inhibition in the DNA damage and repair pathway. J Clin Oncol 2008;26:3259-67.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3259-3267
-
-
Weberpals, J.I.1
Clark-Knowles, K.V.2
Vanderhyden, B.C.3
-
48
-
-
24044477224
-
Defective binding of transcriptional repressor ZEB via DNA methylation contributes to increased constitutive levels of p73 in Fanconi anemia cells
-
Pipaon C, Real PJ, Fernandez-Luna JL. Defective binding of transcriptional repressor ZEB via DNA methylation contributes to increased constitutive levels of p73 in Fanconi anemia cells. FEBS Lett 2005;579:4610-4.
-
(2005)
FEBS Lett
, vol.579
, pp. 4610-4614
-
-
Pipaon, C.1
Real, P.J.2
Fernandez-Luna, J.L.3
|