Deletion of p66shc in mice increases the frequency of size-change mutations in the lacZ transgene

Aging Cell

Volumn 12, Issue 2, 2013, Pages 177-183

  Beltrami, Elena ^a   Ruggiero, Antonella ^a   Busuttil, Rita ^b,c   Migliaccio, Enrica ^a   Pelicci, Pier Giuseppe ^a   Vijg, Jan ^d   Giorgio, Marco ^a  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Cell death; Longevity genes; Mice; Mitochondria; Mutagenesis; Reactive oxygen species

Indexed keywords

BETA GALACTOSIDASE; CYCLOPHILIN D; PROTEIN P66; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; EMBRYO; ESCHERICHIA COLI; FIBROBLAST; GENE SILENCING; IN VIVO STUDY; MOUSE; MUTATION RATE; NONHUMAN; OXIDATIVE STRESS; PLASMID; PRIORITY JOURNAL; REPORTER GENE; SPONTANEOUS MUTATION; X IRRADIATION;

ANIMALS; CYCLOPHILINS; ESCHERICHIA COLI; GAMMA RAYS; GENE EXPRESSION REGULATION; HYDROGEN PEROXIDE; INTESTINE, SMALL; LAC OPERON; LIVER; MICE; MICE, KNOCKOUT; MUTATION; MUTATION RATE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SHC SIGNALING ADAPTOR PROTEINS; SIGNAL TRANSDUCTION; TRANSGENES;

ESCHERICHIA COLI; MUS;

EID: 84878927102     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12036     Document Type: Article

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