Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 596, Issue 1-2 SPEC. ISS., 2006, Pages 22-35

  Dollé, Martijn E T ^a   Busuttil, Rita A ^b   Garcia, Ana Maria ^d   Wijnhoven, Susan ^a   van Drunen, Ellen ^c   Niedernhofer, Laura J ^c   van der Horst, Gijsbertus ^c   Hoeijmakers, Jan H J ^c   van Steeg, Harry ^a   Vijg, Jan ^b  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

Aging; DNA repair; Mice; Mutation

Indexed keywords

BETA GALACTOSIDASE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA REPAIR; GENE DELETION; GENE FREQUENCY; GENE MUTATION; GENE REARRANGEMENT; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; KIDNEY; LIFESPAN; LIVER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; REPORTER GENE; SOMATIC MUTATION;

AGING, PREMATURE; ANIMALS; BASE SEQUENCE; BETA-GALACTOSIDASE; CHROMOSOME MAPPING; CROSSES, GENETIC; DNA PRIMERS; DNA REPAIR; GENE REARRANGEMENT; GENES, REPORTER; GENOME; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MUTATION;

EID: 33645980992     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2005.11.008     Document Type: Article

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