-
1
-
-
23744470219
-
Mechanisms of neuropeptide Y, peptide YY, and pancreatic polypeptide inhibition of identified green fluorescent protein-expressing GABA neurons in the hypothalamic neuroendocrine arcuate nucleus
-
Acuna-Goycolea, C., Tamamaki, N., Yanagawa, Y., Obata, K., and Van Den Pol, A. N. (2005). Mechanisms of neuropeptide Y, peptide YY, and pancreatic polypeptide inhibition of identified green fluorescent protein-expressing GABA neurons in the hypothalamic neuroendocrine arcuate nucleus. J. Neurosci. 25, 7406-7419.
-
(2005)
J. Neurosci.
, vol.25
, pp. 7406-7419
-
-
Acuna-Goycolea, C.1
Tamamaki, N.2
Yanagawa, Y.3
Obata, K.4
Van Den Pol, A.N.5
-
2
-
-
70350389400
-
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons
-
Al-Qassab, H., Smith, M. A., Irvine, E. E., Guillermet-Guibert, J., Claret, M., Choudhury, A. I., et al. (2009). Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons. Cell Metab. 10, 343-354.
-
(2009)
Cell Metab.
, vol.10
, pp. 343-354
-
-
Al-Qassab, H.1
Smith, M.A.2
Irvine, E.E.3
Guillermet-Guibert, J.4
Claret, M.5
Choudhury, A.I.6
-
3
-
-
0023911193
-
Adenosine 5'-triphosphate-sensitive potassium channels
-
Ashcroft, F. M. (1988). Adenosine 5'-triphosphate-sensitive potassium channels. Annu. Rev. Neurosci. 11, 97-118.
-
(1988)
Annu. Rev. Neurosci.
, vol.11
, pp. 97-118
-
-
Ashcroft, F.M.1
-
4
-
-
0025162079
-
Glucose-induced excitation of hypothalamic neurones is mediated by ATP-sensitive K+ channels
-
Ashford, M. L., Boden, P. R., and Treherne, J. M. (1990). Glucose-induced excitation of hypothalamic neurones is mediated by ATP-sensitive K+ channels. Pflugers Arch. 415, 479-483.
-
(1990)
Pflugers Arch.
, vol.415
, pp. 479-483
-
-
Ashford, M.L.1
Boden, P.R.2
Treherne, J.M.3
-
5
-
-
84864711337
-
Deconstruction of a neural circuit for hunger
-
Atasoy, D., Betley, J. N., Su, H. H., and Sternson, S. M. (2012). Deconstruction of a neural circuit for hunger. Nature 488, 172-177.
-
(2012)
Nature
, vol.488
, pp. 172-177
-
-
Atasoy, D.1
Betley, J.N.2
Su, H.H.3
Sternson, S.M.4
-
6
-
-
0033567543
-
Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain
-
Bagnol, D., Lu, X. Y., Kaelin, C. B., Day, H. E., Ollmann, M., Gantz, I., et al. (1999). Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain. J. Neurosci. 19, RC26.
-
(1999)
J. Neurosci.
, vol.19
-
-
Bagnol, D.1
Lu, X.Y.2
Kaelin, C.B.3
Day, H.E.4
Ollmann, M.5
Gantz, I.6
-
7
-
-
0029099078
-
Arcuate nucleus neurons that project to the hypothalamic paraventricular nucleus: neuropeptidergic identity and consequences of adrenalectomy on mRNA levels in the rat
-
Baker, R. A., and Herkenham, M. (1995). Arcuate nucleus neurons that project to the hypothalamic paraventricular nucleus: neuropeptidergic identity and consequences of adrenalectomy on mRNA levels in the rat. J. Comp. Neurol. 358, 518-530.
-
(1995)
J. Comp. Neurol.
, vol.358
, pp. 518-530
-
-
Baker, R.A.1
Herkenham, M.2
-
8
-
-
2942733252
-
Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis
-
Balthasar, N., Coppari, R., McMinn, J., Liu, S. M., Lee, C. E., Tang, V., et al. (2004). Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis. Neuron 42, 983-991.
-
(2004)
Neuron
, vol.42
, pp. 983-991
-
-
Balthasar, N.1
Coppari, R.2
McMinn, J.3
Liu, S.M.4
Lee, C.E.5
Tang, V.6
-
9
-
-
27544450765
-
Divergence of melanocortin pathways in the control of food intake and energy expenditure
-
Balthasar, N., Dalgaard, L. T., Lee, C. E., Yu, J., Funahashi, H., Williams, T., et al. (2005). Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell 123, 493-505.
-
(2005)
Cell
, vol.123
, pp. 493-505
-
-
Balthasar, N.1
Dalgaard, L.T.2
Lee, C.E.3
Yu, J.4
Funahashi, H.5
Williams, T.6
-
10
-
-
78649466467
-
CNS leptin and insulin action in the control of energy homeostasis
-
Belgardt, B. F., and Bruning, J. C. (2010). CNS leptin and insulin action in the control of energy homeostasis. Ann. N.Y. Acad. Sci. 1212, 97-113.
-
(2010)
Ann. N.Y. Acad. Sci.
, vol.1212
, pp. 97-113
-
-
Belgardt, B.F.1
Bruning, J.C.2
-
11
-
-
14644396121
-
Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ
-
Burdakov, D., Gerasimenko, O., and Verkhratsky, A. (2005). Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ. J. Neurosci. 25, 2429-2433.
-
(2005)
J. Neurosci.
, vol.25
, pp. 2429-2433
-
-
Burdakov, D.1
Gerasimenko, O.2
Verkhratsky, A.3
-
12
-
-
33646914929
-
Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose
-
Burdakov, D., Jensen, L. T., Alexopoulos, H., Williams, R. H., Fearon, I. M., O'Kelly, I., et al. (2006). Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose. Neuron 50, 711-722.
-
(2006)
Neuron
, vol.50
, pp. 711-722
-
-
Burdakov, D.1
Jensen, L.T.2
Alexopoulos, H.3
Williams, R.H.4
Fearon, I.M.5
O'Kelly, I.6
-
13
-
-
0029048408
-
Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield, L. A., Smith, F. J., Guisez, Y., Devos, R., and Burn, P. (1995). Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269, 546-549.
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
14
-
-
0028133318
-
Organization of projections from the ventromedial nucleus of the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat
-
Canteras, N. S., Simerly, R. B., and Swanson, L. W. (1994). Organization of projections from the ventromedial nucleus of the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat. J. Comp. Neurol. 348, 41-79.
-
(1994)
J. Comp. Neurol.
, vol.348
, pp. 41-79
-
-
Canteras, N.S.1
Simerly, R.B.2
Swanson, L.W.3
-
15
-
-
77749310482
-
Neuropeptide Y suppresses anorexigenic output from the ventromedial nucleus of the hypothalamus
-
Chee, M. J., Myers, M. G. Jr., Price, C. J., and Colmers, W. F. (2010). Neuropeptide Y suppresses anorexigenic output from the ventromedial nucleus of the hypothalamus. J. Neurosci. 30, 3380-3390.
-
(2010)
J. Neurosci.
, vol.30
, pp. 3380-3390
-
-
Chee, M.J.1
Myers, Jr.M.G.2
Price, C.J.3
Colmers, W.F.4
-
16
-
-
17644428076
-
Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons
-
Chen, X., and Johnston, D. (2005). Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons. J. Neurosci. 25, 3787-3792.
-
(2005)
J. Neurosci.
, vol.25
, pp. 3787-3792
-
-
Chen, X.1
Johnston, D.2
-
17
-
-
20144389727
-
The role of insulin receptor substrate 2 in hypothalamic and beta cell function
-
Choudhury, A. I., Heffron, H., Smith, M. A., Al-Qassab, H., Xu, A. W., Selman, C., et al. (2005). The role of insulin receptor substrate 2 in hypothalamic and beta cell function. J. Clin. Invest. 115, 940-950.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 940-950
-
-
Choudhury, A.I.1
Heffron, H.2
Smith, M.A.3
Al-Qassab, H.4
Xu, A.W.5
Selman, C.6
-
18
-
-
34547651092
-
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
-
Claret, M., Smith, M. A., Batterham, R. L., Selman, C., Choudhury, A. I., Fryer, L. G., et al. (2007). AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J. Clin. Invest. 117, 2325-2336.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2325-2336
-
-
Claret, M.1
Smith, M.A.2
Batterham, R.L.3
Selman, C.4
Choudhury, A.I.5
Fryer, L.G.6
-
19
-
-
0034776770
-
Selective deletion of leptin receptor in neurons leads to obesity
-
Cohen, P., Zhao, C., Cai, X., Montez, J. M., Rohani, S. C., Feinstein, P., et al. (2001). Selective deletion of leptin receptor in neurons leads to obesity. J. Clin. Invest. 108, 1113-1121.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1113-1121
-
-
Cohen, P.1
Zhao, C.2
Cai, X.3
Montez, J.M.4
Rohani, S.C.5
Feinstein, P.6
-
20
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
Cowley, M. A., Smart, J. L., Rubinstein, M., Cerdan, M. G., Diano, S., Horvath, T. L., et al. (2001). Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 411, 480-484.
-
(2001)
Nature
, vol.411
, pp. 480-484
-
-
Cowley, M.A.1
Smart, J.L.2
Rubinstein, M.3
Cerdan, M.G.4
Diano, S.5
Horvath, T.L.6
-
21
-
-
0037456519
-
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
-
Cowley, M. A., Smith, R. G., Diano, S., Tschop, M., Pronchuk, N., Grove, K. L., et al. (2003). The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 37, 649-661.
-
(2003)
Neuron
, vol.37
, pp. 649-661
-
-
Cowley, M.A.1
Smith, R.G.2
Diano, S.3
Tschop, M.4
Pronchuk, N.5
Grove, K.L.6
-
22
-
-
1642499473
-
Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system
-
Cruz, H. G., Ivanova, T., Lunn, M. L., Stoffel, M., Slesinger, P. A., and Luscher, C. (2004). Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system. Nat. Neurosci. 7, 153-159.
-
(2004)
Nat. Neurosci.
, vol.7
, pp. 153-159
-
-
Cruz, H.G.1
Ivanova, T.2
Lunn, M.L.3
Stoffel, M.4
Slesinger, P.A.5
Luscher, C.6
-
23
-
-
84867750916
-
Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area
-
Cui, H., Sohn, J. W., Gautron, L., Funahashi, H., Williams, K. W., Elmquist, J. K., et al. (2012). Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area. J. Comp. Neurol. 520, 4168-4183.
-
(2012)
J. Comp. Neurol.
, vol.520
, pp. 4168-4183
-
-
Cui, H.1
Sohn, J.W.2
Gautron, L.3
Funahashi, H.4
Williams, K.W.5
Elmquist, J.K.6
-
24
-
-
27644518764
-
Pathways modulating neural KCNQ/M (Kv7) potassium channels
-
Delmas, P., and Brown, D. A. (2005). Pathways modulating neural KCNQ/M (Kv7) potassium channels. Nat. Rev. Neurosci. 6, 850-862.
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, pp. 850-862
-
-
Delmas, P.1
Brown, D.A.2
-
25
-
-
30644473109
-
Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
-
Dhillon, H., Zigman, J. M., Ye, C., Lee, C. E., McGovern, R. A., Tang, V., et al. (2006). Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 49, 191-203.
-
(2006)
Neuron
, vol.49
, pp. 191-203
-
-
Dhillon, H.1
Zigman, J.M.2
Ye, C.3
Lee, C.E.4
McGovern, R.A.5
Tang, V.6
-
26
-
-
0032436307
-
Leptin activates hypothalamic CART neurons projecting to the spinal cord
-
Elias, C. F., Lee, C., Kelly, J., Aschkenasi, C., Ahima, R. S., Couceyro, P. R., et al. (1998). Leptin activates hypothalamic CART neurons projecting to the spinal cord. Neuron 21, 1375-1385.
-
(1998)
Neuron
, vol.21
, pp. 1375-1385
-
-
Elias, C.F.1
Lee, C.2
Kelly, J.3
Aschkenasi, C.4
Ahima, R.S.5
Couceyro, P.R.6
-
27
-
-
0035953173
-
Characterization of CART neurons in the rat and human hypothalamus
-
Elias, C. F., Lee, C. E., Kelly, J. F., Ahima, R. S., Kuhar, M., Saper, C. B., et al. (2001). Characterization of CART neurons in the rat and human hypothalamus. J. Comp. Neurol. 432, 1-19.
-
(2001)
J. Comp. Neurol.
, vol.432
, pp. 1-19
-
-
Elias, C.F.1
Lee, C.E.2
Kelly, J.F.3
Ahima, R.S.4
Kuhar, M.5
Saper, C.B.6
-
28
-
-
0033575993
-
Effects of recombinant leptin therapy in a child with congenital leptin deficiency
-
Farooqi, I. S., Jebb, S. A., Langmack, G., Lawrence, E., Cheetham, C. H., Prentice, A. M., et al. (1999). Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N. Engl. J. Med. 341, 879-884.
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 879-884
-
-
Farooqi, I.S.1
Jebb, S.A.2
Langmack, G.3
Lawrence, E.4
Cheetham, C.H.5
Prentice, A.M.6
-
29
-
-
0037456768
-
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
-
Farooqi, I. S., Keogh, J. M., Yeo, G. S., Lank, E. J., Cheetham, T., and O'Rahilly, S. (2003). Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N. Engl. J. Med. 348, 1085-1095.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1085-1095
-
-
Farooqi, I.S.1
Keogh, J.M.2
Yeo, G.S.3
Lank, E.J.4
Cheetham, T.5
O'Rahilly, S.6
-
30
-
-
34248204584
-
Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opio melanocortin networks?
-
Fioramonti, X., Contie, S., Song, Z., Routh, V. H., Lorsignol, A., and Penicaud, L. (2007). Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opio melanocortin networks? Diabetes 56, 1219-1227.
-
(2007)
Diabetes
, vol.56
, pp. 1219-1227
-
-
Fioramonti, X.1
Contie, S.2
Song, Z.3
Routh, V.H.4
Lorsignol, A.5
Penicaud, L.6
-
31
-
-
77955629618
-
Muscle KATP channels: recent insights to energy sensing and myoprotection
-
Flagg, T. P., Enkvetchakul, D., Koster, J. C., and Nichols, C. G. (2010). Muscle KATP channels: recent insights to energy sensing and myoprotection. Physiol. Rev. 90, 799-829.
-
(2010)
Physiol. Rev.
, vol.90
, pp. 799-829
-
-
Flagg, T.P.1
Enkvetchakul, D.2
Koster, J.C.3
Nichols, C.G.4
-
32
-
-
5444263310
-
Neuropeptide Y inhibits hypocretin/orexin neurons by multiple presynaptic and postsynaptic mechanisms: tonic depression of the hypothalamic arousal system
-
Fu, L. Y., Acuna-Goycolea, C., and Van Den Pol, A. N. (2004). Neuropeptide Y inhibits hypocretin/orexin neurons by multiple presynaptic and postsynaptic mechanisms: tonic depression of the hypothalamic arousal system. J. Neurosci. 24, 8741-8751.
-
(2004)
J. Neurosci.
, vol.24
, pp. 8741-8751
-
-
Fu, L.Y.1
Acuna-Goycolea, C.2
Van Den Pol, A.N.3
-
33
-
-
58149391976
-
Monitoring FoxO1 localization in chemically identified neurons
-
Fukuda, M., Jones, J. E., Olson, D., Hill, J., Lee, C. E., Gautron, L., et al. (2008). Monitoring FoxO1 localization in chemically identified neurons. J. Neurosci. 28, 13640-13648.
-
(2008)
J. Neurosci.
, vol.28
, pp. 13640-13648
-
-
Fukuda, M.1
Jones, J.E.2
Olson, D.3
Hill, J.4
Lee, C.E.5
Gautron, L.6
-
34
-
-
78649369301
-
Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens
-
Grueter, B. A., Brasnjo, G., and Malenka, R. C. (2010). Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens. Nat. Neurosci. 13, 1519-1525.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1519-1525
-
-
Grueter, B.A.1
Brasnjo, G.2
Malenka, R.C.3
-
35
-
-
61449104516
-
Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels
-
Guyon, A., Tardy, M. P., Rovere, C., Nahon, J. L., Barhanin, J., and Lesage, F. (2009). Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels. J. Neurosci. 29, 2528-2533.
-
(2009)
J. Neurosci.
, vol.29
, pp. 2528-2533
-
-
Guyon, A.1
Tardy, M.P.2
Rovere, C.3
Nahon, J.L.4
Barhanin, J.5
Lesage, F.6
-
36
-
-
0030737953
-
Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
-
Halaas, J. L., Boozer, C., Blair-West, J., Fidahusein, N., Denton, D. A., and Friedman, J. M. (1997). Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc. Natl. Acad. Sci. U.S.A. 94, 8878-8883.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 8878-8883
-
-
Halaas, J.L.1
Boozer, C.2
Blair-West, J.3
Fidahusein, N.4
Denton, D.A.5
Friedman, J.M.6
-
37
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas, J. L., Gajiwala, K. S., Maffei, M., Cohen, S. L., Chait, B. T., Rabinowitz, D., et al. (1995). Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269, 543-546.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
-
39
-
-
48749132328
-
TRPC3 channels are required for synaptic transmission and motor coordination
-
Hartmann, J., Dragicevic, E., Adelsberger, H., Henning, H. A., Sumser, M., Abramowitz, J., et al. (2008). TRPC3 channels are required for synaptic transmission and motor coordination. Neuron 59, 392-398.
-
(2008)
Neuron
, vol.59
, pp. 392-398
-
-
Hartmann, J.1
Dragicevic, E.2
Adelsberger, H.3
Henning, H.A.4
Sumser, M.5
Abramowitz, J.6
-
40
-
-
0030025724
-
Cloning of a Xenopus laevis inwardly rectifying K+ channel subunit that permits GIRK1 expression of IKACh currents in oocytes
-
Hedin, K. E., Lim, N. F., and Clapham, D. E. (1996). Cloning of a Xenopus laevis inwardly rectifying K+ channel subunit that permits GIRK1 expression of IKACh currents in oocytes. Neuron 16, 423-429.
-
(1996)
Neuron
, vol.16
, pp. 423-429
-
-
Hedin, K.E.1
Lim, N.F.2
Clapham, D.E.3
-
41
-
-
0037178730
-
Activation of central melanocortin pathways by fenfluramine
-
Heisler, L. K., Cowley, M. A., Tecott, L. H., Fan, W., Low, M. J., Smart, J. L., et al. (2002). Activation of central melanocortin pathways by fenfluramine. Science 297, 609-611.
-
(2002)
Science
, vol.297
, pp. 609-611
-
-
Heisler, L.K.1
Cowley, M.A.2
Tecott, L.H.3
Fan, W.4
Low, M.J.5
Smart, J.L.6
-
42
-
-
33745978779
-
Serotonin reciprocally regulates melanocortin neurons to modulate food intake
-
Heisler, L. K., Jobst, E. E., Sutton, G. M., Zhou, L., Borok, E., Thornton-Jones, Z., et al. (2006). Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron 51, 239-249.
-
(2006)
Neuron
, vol.51
, pp. 239-249
-
-
Heisler, L.K.1
Jobst, E.E.2
Sutton, G.M.3
Zhou, L.4
Borok, E.5
Thornton-Jones, Z.6
-
43
-
-
74949143771
-
Inwardly rectifying potassium channels: their structure, function, and physiological roles
-
Hibino, H., Inanobe, A., Furutani, K., Murakami, S., Findlay, I., and Kurachi, Y. (2010). Inwardly rectifying potassium channels: their structure, function, and physiological roles. Physiol. Rev. 90, 291-366.
-
(2010)
Physiol. Rev.
, vol.90
, pp. 291-366
-
-
Hibino, H.1
Inanobe, A.2
Furutani, K.3
Murakami, S.4
Findlay, I.5
Kurachi, Y.6
-
44
-
-
77950264425
-
Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility
-
Hill, J. W., Elias, C. F., Fukuda, M., Williams, K. W., Berglund, E. D., Holland, W. L., et al. (2010). Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metab. 11, 286-297.
-
(2010)
Cell Metab.
, vol.11
, pp. 286-297
-
-
Hill, J.W.1
Elias, C.F.2
Fukuda, M.3
Williams, K.W.4
Berglund, E.D.5
Holland, W.L.6
-
45
-
-
43049116846
-
Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice
-
Hill, J. W., Williams, K. W., Ye, C., Luo, J., Balthasar, N., Coppari, R., et al. (2008). Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice. J. Clin. Invest. 118, 1796-1805.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1796-1805
-
-
Hill, J.W.1
Williams, K.W.2
Ye, C.3
Luo, J.4
Balthasar, N.5
Coppari, R.6
-
47
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar, D., Lynch, C. A., Fairchild-Huntress, V., Dunmore, J. H., Fang, Q., Berkemeier, L. R., et al. (1997). Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88, 131-141.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
-
48
-
-
0037387207
-
Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels
-
Ibrahim, N., Bosch, M. A., Smart, J. L., Qiu, J., Rubinstein, M., Ronnekleiv, O. K., et al. (2003). Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels. Endocrinology 144, 1331-1340.
-
(2003)
Endocrinology
, vol.144
, pp. 1331-1340
-
-
Ibrahim, N.1
Bosch, M.A.2
Smart, J.L.3
Qiu, J.4
Rubinstein, M.5
Ronnekleiv, O.K.6
-
49
-
-
0032102985
-
KATP channel formation by the sulphonylurea receptors SUR1 with Kir6.2 subunits in rat dorsal vagal neurons in situ
-
Karschin, A., Brockhaus, J., and Ballanyi, K. (1998). KATP channel formation by the sulphonylurea receptors SUR1 with Kir6.2 subunits in rat dorsal vagal neurons in situ. J. Physiol. 509, 339-346.
-
(1998)
J. Physiol.
, vol.509
, pp. 339-346
-
-
Karschin, A.1
Brockhaus, J.2
Ballanyi, K.3
-
50
-
-
0029959793
-
Localization and interaction of epitope-tagged GIRK1 and CIR inward rectifier K+ channel subunits
-
Kennedy, M. E., Nemec, J., and Clapham, D. E. (1996). Localization and interaction of epitope-tagged GIRK1 and CIR inward rectifier K+ channel subunits. Neuropharmacology 35, 831-839.
-
(1996)
Neuropharmacology
, vol.35
, pp. 831-839
-
-
Kennedy, M.E.1
Nemec, J.2
Clapham, D.E.3
-
51
-
-
0033593226
-
GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels
-
Kennedy, M. E., Nemec, J., Corey, S., Wickman, K., and Clapham, D. E. (1999). GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels. J. Biol. Chem. 274, 2571-2582.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2571-2582
-
-
Kennedy, M.E.1
Nemec, J.2
Corey, S.3
Wickman, K.4
Clapham, D.E.5
-
52
-
-
84861447770
-
TRPV1 in GABAergic interneurons mediates neuropathic mechanical allodynia and disinhibition of the nociceptive circuitry in the spinal cord
-
Kim, Y. H., Back, S. K., Davies, A. J., Jeong, H., Jo, H. J., Chung, G., et al. (2012). TRPV1 in GABAergic interneurons mediates neuropathic mechanical allodynia and disinhibition of the nociceptive circuitry in the spinal cord. Neuron 74, 640-647.
-
(2012)
Neuron
, vol.74
, pp. 640-647
-
-
Kim, Y.H.1
Back, S.K.2
Davies, A.J.3
Jeong, H.4
Jo, H.J.5
Chung, G.6
-
53
-
-
0037430140
-
Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat
-
Kishi, T., Aschkenasi, C. J., Lee, C. E., Mountjoy, K. G., Saper, C. B., and Elmquist, J. K. (2003). Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat. J. Comp. Neurol. 457, 213-235.
-
(2003)
J. Comp. Neurol.
, vol.457
, pp. 213-235
-
-
Kishi, T.1
Aschkenasi, C.J.2
Lee, C.E.3
Mountjoy, K.G.4
Saper, C.B.5
Elmquist, J.K.6
-
54
-
-
79959652223
-
High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons
-
Klockener, T., Hess, S., Belgardt, B. F., Paeger, L., Verhagen, L. A., Husch, A., et al. (2011). High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nat. Neurosci. 14, 911-918.
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 911-918
-
-
Klockener, T.1
Hess, S.2
Belgardt, B.F.3
Paeger, L.4
Verhagen, L.A.5
Husch, A.6
-
55
-
-
78049433920
-
Glucose stimulation of hypothalamic MCH neurons involves K(ATP) channels, is modulated by UCP2, and regulates peripheral glucose homeostasis
-
Kong, D., Vong, L., Parton, L. E., Ye, C., Tong, Q., Hu, X., et al. (2010). Glucose stimulation of hypothalamic MCH neurons involves K(ATP) channels, is modulated by UCP2, and regulates peripheral glucose homeostasis. Cell Metab. 12, 545-552.
-
(2010)
Cell Metab.
, vol.12
, pp. 545-552
-
-
Kong, D.1
Vong, L.2
Parton, L.E.3
Ye, C.4
Tong, Q.5
Hu, X.6
-
56
-
-
30544431963
-
Molecular and cellular diversity of neuronal G-protein-gated potassium channels
-
Koyrakh, L., Lujan, R., Colon, J., Karschin, C., Kurachi, Y., Karschin, A., et al. (2005). Molecular and cellular diversity of neuronal G-protein-gated potassium channels. J. Neurosci. 25, 11468-11478.
-
(2005)
J. Neurosci.
, vol.25
, pp. 11468-11478
-
-
Koyrakh, L.1
Lujan, R.2
Colon, J.3
Karschin, C.4
Kurachi, Y.5
Karschin, A.6
-
57
-
-
0028934859
-
The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins
-
Krapivinsky, G., Gordon, E. A., Wickman, K., Velimirovic, B., Krapivinsky, L., and Clapham, D. E. (1995). The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins. Nature 374, 135-141.
-
(1995)
Nature
, vol.374
, pp. 135-141
-
-
Krapivinsky, G.1
Gordon, E.A.2
Wickman, K.3
Velimirovic, B.4
Krapivinsky, L.5
Clapham, D.E.6
-
58
-
-
0041624549
-
Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter
-
Liu, H., Kishi, T., Roseberry, A. G., Cai, X., Lee, C. E., Montez, J. M., et al. (2003). Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter. J. Neurosci. 23, 7143-7154.
-
(2003)
J. Neurosci.
, vol.23
, pp. 7143-7154
-
-
Liu, H.1
Kishi, T.2
Roseberry, A.G.3
Cai, X.4
Lee, C.E.5
Montez, J.M.6
-
59
-
-
84863012024
-
Fasting activation of AgRP neurons requires NMDA receptors and involves spinogenesis and increased excitatory tone
-
Liu, T., Kong, D., Shah, B. P., Ye, C., Koda, S., Saunders, A., et al. (2012). Fasting activation of AgRP neurons requires NMDA receptors and involves spinogenesis and increased excitatory tone. Neuron 73, 511-522.
-
(2012)
Neuron
, vol.73
, pp. 511-522
-
-
Liu, T.1
Kong, D.2
Shah, B.P.3
Ye, C.4
Koda, S.5
Saunders, A.6
-
60
-
-
0039357820
-
G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons
-
Luscher, C., Jan, L. Y., Stoffel, M., Malenka, R. C., and Nicoll, R. A. (1997). G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron 19, 687-695.
-
(1997)
Neuron
, vol.19
, pp. 687-695
-
-
Luscher, C.1
Jan, L.Y.2
Stoffel, M.3
Malenka, R.C.4
Nicoll, R.A.5
-
61
-
-
77951498231
-
Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease
-
Luscher, C., and Slesinger, P. A. (2010). Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease. Nat. Rev. Neurosci. 11, 301-315.
-
(2010)
Nat. Rev. Neurosci.
, vol.11
, pp. 301-315
-
-
Luscher, C.1
Slesinger, P.A.2
-
62
-
-
0037186091
-
Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart
-
Ma, D., Zerangue, N., Raab-Graham, K., Fried, S. R., Jan, Y. N., and Jan, L. Y. (2002). Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart. Neuron 33, 715-729.
-
(2002)
Neuron
, vol.33
, pp. 715-729
-
-
Ma, D.1
Zerangue, N.2
Raab-Graham, K.3
Fried, S.R.4
Jan, Y.N.5
Jan, L.Y.6
-
63
-
-
0035042796
-
ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis
-
Miki, T., Liss, B., Minami, K., Shiuchi, T., Saraya, A., Kashima, Y., et al. (2001). ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis. Nat. Neurosci. 4, 507-512.
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 507-512
-
-
Miki, T.1
Liss, B.2
Minami, K.3
Shiuchi, T.4
Saraya, A.5
Kashima, Y.6
-
64
-
-
12944261926
-
Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation
-
doi: 10.1186/1471-2202-5-54
-
Mirshamsi, S., Laidlaw, H. A., Ning, K., Anderson, E., Burgess, L. A., Gray, A., et al. (2004). Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation. BMC Neurosci. 5:54. doi: 10.1186/1471-2202-5-54
-
(2004)
BMC Neurosci.
, vol.5
, pp. 54
-
-
Mirshamsi, S.1
Laidlaw, H.A.2
Ning, K.3
Anderson, E.4
Burgess, L.A.5
Gray, A.6
-
65
-
-
33644665508
-
Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling
-
Morrison, C. D., Morton, G. J., Niswender, K. D., Gelling, R. W., and Schwartz, M. W. (2005). Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling. Am. J. Physiol. Endocrinol. Metab. 289, E1051-E1057.
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.289
-
-
Morrison, C.D.1
Morton, G.J.2
Niswender, K.D.3
Gelling, R.W.4
Schwartz, M.W.5
-
66
-
-
84857418759
-
Capricious Cre: the devil is in the details
-
Morrison, C. D., and Munzberg, H. (2012). Capricious Cre: the devil is in the details. Endocrinology 153, 1005-1007.
-
(2012)
Endocrinology
, vol.153
, pp. 1005-1007
-
-
Morrison, C.D.1
Munzberg, H.2
-
67
-
-
30044447631
-
Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons
-
Morton, G. J., Gelling, R. W., Niswender, K. D., Morrison, C. D., Rhodes, C. J., and Schwartz, M. W. (2005). Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell Metab. 2, 411-420.
-
(2005)
Cell Metab.
, vol.2
, pp. 411-420
-
-
Morton, G.J.1
Gelling, R.W.2
Niswender, K.D.3
Morrison, C.D.4
Rhodes, C.J.5
Schwartz, M.W.6
-
68
-
-
0035950093
-
Intracellular signalling. Key enzyme in leptin-induced anorexia
-
Niswender, K. D., Morton, G. J., Stearns, W. H., Rhodes, C. J., Myers, M. G. Jr., and Schwartz, M. W. (2001). Intracellular signalling. Key enzyme in leptin-induced anorexia. Nature 413, 794-795.
-
(2001)
Nature
, vol.413
, pp. 794-795
-
-
Niswender, K.D.1
Morton, G.J.2
Stearns, W.H.3
Rhodes, C.J.4
Myers, Jr.M.G.5
Schwartz, M.W.6
-
69
-
-
0036913187
-
Hypothalamic insulin signaling is required for inhibition of glucose production
-
Obici, S., Zhang, B. B., Karkanias, G., and Rossetti, L. (2002). Hypothalamic insulin signaling is required for inhibition of glucose production. Nat. Med. 8, 1376-1382.
-
(2002)
Nat. Med.
, vol.8
, pp. 1376-1382
-
-
Obici, S.1
Zhang, B.B.2
Karkanias, G.3
Rossetti, L.4
-
70
-
-
0016191102
-
Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus
-
Oomura, Y., Ooyama, H., Sugimori, M., Nakamura, T., and Yamada, Y. (1974). Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus. Nature 247, 284-286.
-
(1974)
Nature
, vol.247
, pp. 284-286
-
-
Oomura, Y.1
Ooyama, H.2
Sugimori, M.3
Nakamura, T.4
Yamada, Y.5
-
71
-
-
77950547451
-
Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits
-
Padilla, S. L., Carmody, J. S., and Zeltser, L. M. (2010). Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits. Nat. Med. 16, 403-405.
-
(2010)
Nat. Med.
, vol.16
, pp. 403-405
-
-
Padilla, S.L.1
Carmody, J.S.2
Zeltser, L.M.3
-
72
-
-
84857418715
-
Defining POMC neurons using transgenic reagents: impact of transient Pomc expression in diverse immature neuronal populations
-
Padilla, S. L., Reef, D., and Zeltser, L. M. (2012). Defining POMC neurons using transgenic reagents: impact of transient Pomc expression in diverse immature neuronal populations. Endocrinology 153, 1219-1231.
-
(2012)
Endocrinology
, vol.153
, pp. 1219-1231
-
-
Padilla, S.L.1
Reef, D.2
Zeltser, L.M.3
-
73
-
-
34548604499
-
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
-
Parton, L. E., Ye, C. P., Coppari, R., Enriori, P. J., Choi, B., Zhang, C. Y., et al. (2007). Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. Nature 449, 228-232.
-
(2007)
Nature
, vol.449
, pp. 228-232
-
-
Parton, L.E.1
Ye, C.P.2
Coppari, R.3
Enriori, P.J.4
Choi, B.5
Zhang, C.Y.6
-
74
-
-
45849107222
-
Predisposition to late-onset obesity in GIRK4 knockout mice
-
Perry, C. A., Pravetoni, M., Teske, J. A., Aguado, C., Erickson, D. J., Medrano, J. F., et al. (2008). Predisposition to late-onset obesity in GIRK4 knockout mice. Proc. Natl. Acad. Sci. U.S.A. 105, 8148-8153.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 8148-8153
-
-
Perry, C.A.1
Pravetoni, M.2
Teske, J.A.3
Aguado, C.4
Erickson, D.J.5
Medrano, J.F.6
-
75
-
-
1842529267
-
Rapid rewiring of arcuate nucleus feeding circuits by leptin
-
Pinto, S., Roseberry, A. G., Liu, H., Diano, S., Shanabrough, M., Cai, X., et al. (2004). Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science 304, 110-115.
-
(2004)
Science
, vol.304
, pp. 110-115
-
-
Pinto, S.1
Roseberry, A.G.2
Liu, H.3
Diano, S.4
Shanabrough, M.5
Cai, X.6
-
76
-
-
33745819212
-
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity
-
Plum, L., Ma, X., Hampel, B., Balthasar, N., Coppari, R., Munzberg, H., et al. (2006). Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity. J. Clin. Invest. 116, 1886-1901.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1886-1901
-
-
Plum, L.1
Ma, X.2
Hampel, B.3
Balthasar, N.4
Coppari, R.5
Munzberg, H.6
-
77
-
-
79953211082
-
Guinea pig kisspeptin neurons are depolarized by leptin via activation of TRPC channels
-
Qiu, J., Fang, Y., Bosch, M. A., Ronnekleiv, O. K., and Kelly, M. J. (2011). Guinea pig kisspeptin neurons are depolarized by leptin via activation of TRPC channels. Endocrinology 152, 1503-1514.
-
(2011)
Endocrinology
, vol.152
, pp. 1503-1514
-
-
Qiu, J.1
Fang, Y.2
Bosch, M.A.3
Ronnekleiv, O.K.4
Kelly, M.J.5
-
78
-
-
75349092316
-
Leptin excites proopiomelanocortin neurons via activation of TRPC channels
-
Qiu, J., Fang, Y., Ronnekleiv, O. K., and Kelly, M. J. (2010). Leptin excites proopiomelanocortin neurons via activation of TRPC channels. J. Neurosci. 30, 1560-1565.
-
(2010)
J. Neurosci.
, vol.30
, pp. 1560-1565
-
-
Qiu, J.1
Fang, Y.2
Ronnekleiv, O.K.3
Kelly, M.J.4
-
79
-
-
34748903427
-
Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females
-
Qiu, J., Xue, C., Bosch, M. A., Murphy, J. G., Fan, W., Ronnekleiv, O. K., et al. (2007). Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females. Mol. Pharmacol. 72, 885-896.
-
(2007)
Mol. Pharmacol.
, vol.72
, pp. 885-896
-
-
Qiu, J.1
Xue, C.2
Bosch, M.A.3
Murphy, J.G.4
Fan, W.5
Ronnekleiv, O.K.6
-
80
-
-
0037338694
-
Intracellular mechanisms involved in leptin regulation of sympathetic outflow
-
Rahmouni, K., Haynes, W. G., Morgan, D. A., and Mark, A. L. (2003). Intracellular mechanisms involved in leptin regulation of sympathetic outflow. Hypertension 41, 763-767.
-
(2003)
Hypertension
, vol.41
, pp. 763-767
-
-
Rahmouni, K.1
Haynes, W.G.2
Morgan, D.A.3
Mark, A.L.4
-
81
-
-
65549115483
-
Essential role for TRPC5 in amygdala function and fear-related behavior
-
Riccio, A., Li, Y., Moon, J., Kim, K. S., Smith, K. S., Rudolph, U., et al. (2009). Essential role for TRPC5 in amygdala function and fear-related behavior. Cell 137, 761-772.
-
(2009)
Cell
, vol.137
, pp. 761-772
-
-
Riccio, A.1
Li, Y.2
Moon, J.3
Kim, K.S.4
Smith, K.S.5
Rudolph, U.6
-
82
-
-
84861879399
-
Serotonin 5-HT2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons
-
Roepke, T. A., Smith, A. W., Ronnekleiv, O. K., and Kelly, M. J. (2012). Serotonin 5-HT2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons. Am. J. Physiol. Endocrinol. Metab. 302, E1399-E1406.
-
(2012)
Am. J. Physiol. Endocrinol. Metab.
, vol.302
-
-
Roepke, T.A.1
Smith, A.W.2
Ronnekleiv, O.K.3
Kelly, M.J.4
-
83
-
-
1542358816
-
Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice
-
Roseberry, A. G., Liu, H., Jackson, A. C., Cai, X., and Friedman, J. M. (2004). Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice. Neuron 41, 711-722.
-
(2004)
Neuron
, vol.41
, pp. 711-722
-
-
Roseberry, A.G.1
Liu, H.2
Jackson, A.C.3
Cai, X.4
Friedman, J.M.5
-
84
-
-
79551555006
-
Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis
-
Rossi, J., Balthasar, N., Olson, D., Scott, M., Berglund, E., Lee, C. E., et al. (2011). Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis. Cell Metab. 13, 195-204.
-
(2011)
Cell Metab.
, vol.13
, pp. 195-204
-
-
Rossi, J.1
Balthasar, N.2
Olson, D.3
Scott, M.4
Berglund, E.5
Lee, C.E.6
-
85
-
-
0036065157
-
Glucose-sensing neurons: are they physiologically relevant?
-
Routh, V. H. (2002). Glucose-sensing neurons: are they physiologically relevant? Physiol. Behav. 76, 403-413.
-
(2002)
Physiol. Behav.
, vol.76
, pp. 403-413
-
-
Routh, V.H.1
-
86
-
-
79957896911
-
Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice
-
Scott, M. M., Williams, K. W., Rossi, J., Lee, C. E., and Elmquist, J. K. (2011). Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice. J. Clin. Invest. 121, 2413-2421.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2413-2421
-
-
Scott, M.M.1
Williams, K.W.2
Rossi, J.3
Lee, C.E.4
Elmquist, J.K.5
-
87
-
-
33846191084
-
Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances
-
Smith, M. A., Hisadome, K., Al-Qassab, H., Heffron, H., Withers, D. J., and Ashford, M. L. (2007). Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances. J. Physiol. 578, 425-438.
-
(2007)
J. Physiol.
, vol.578
, pp. 425-438
-
-
Smith, M.A.1
Hisadome, K.2
Al-Qassab, H.3
Heffron, H.4
Withers, D.J.5
Ashford, M.L.6
-
88
-
-
84873301711
-
Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons
-
Sohn, J. W., Harris, L. E., Berglund, E. D., Liu, T., Vong, L., Lowell, B. B., et al. (2013). Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons. Cell 152, 612-619.
-
(2013)
Cell
, vol.152
, pp. 612-619
-
-
Sohn, J.W.1
Harris, L.E.2
Berglund, E.D.3
Liu, T.4
Vong, L.5
Lowell, B.B.6
-
89
-
-
84862675226
-
Functional heterogeneity of arcuate nucleus pro-opiomelanocortin neurons: implications for diverging melanocortin pathways
-
Sohn, J. W., and Williams, K. W. (2012). Functional heterogeneity of arcuate nucleus pro-opiomelanocortin neurons: implications for diverging melanocortin pathways. Mol. Neurobiol. 45, 225-233.
-
(2012)
Mol. Neurobiol.
, vol.45
, pp. 225-233
-
-
Sohn, J.W.1
Williams, K.W.2
-
90
-
-
79961180328
-
Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels
-
Sohn, J. W., Xu, Y., Jones, J. E., Wickman, K., Williams, K. W., and Elmquist, J. K. (2011). Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. Neuron 71, 488-497.
-
(2011)
Neuron
, vol.71
, pp. 488-497
-
-
Sohn, J.W.1
Xu, Y.2
Jones, J.E.3
Wickman, K.4
Williams, K.W.5
Elmquist, J.K.6
-
91
-
-
0035650534
-
Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus
-
Song, Z., Levin, B. E., McArdle, J. J., Bakhos, N., and Routh, V. H. (2001). Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus. Diabetes 50, 2673-2681.
-
(2001)
Diabetes
, vol.50
, pp. 2673-2681
-
-
Song, Z.1
Levin, B.E.2
McArdle, J.J.3
Bakhos, N.4
Routh, V.H.5
-
92
-
-
0031440266
-
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels
-
Spanswick, D., Smith, M. A., Groppi, V. E., Logan, S. D., and Ashford, M. L. (1997). Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels. Nature 390, 521-525.
-
(1997)
Nature
, vol.390
, pp. 521-525
-
-
Spanswick, D.1
Smith, M.A.2
Groppi, V.E.3
Logan, S.D.4
Ashford, M.L.5
-
93
-
-
0033944152
-
Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats
-
Spanswick, D., Smith, M. A., Mirshamsi, S., Routh, V. H., and Ashford, M. L. (2000). Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats. Nat. Neurosci. 3, 757-758.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 757-758
-
-
Spanswick, D.1
Smith, M.A.2
Mirshamsi, S.3
Routh, V.H.4
Ashford, M.L.5
-
94
-
-
0035936764
-
Obesity and the regulation of energy balance
-
Spiegelman, B. M., and Flier, J. S. (2001). Obesity and the regulation of energy balance. Cell 104, 531-543.
-
(2001)
Cell
, vol.104
, pp. 531-543
-
-
Spiegelman, B.M.1
Flier, J.S.2
-
95
-
-
27744457512
-
Topographic mapping of VMH → arcuate nucleus microcircuits and their reorganization by fasting
-
Sternson, S. M., Shepherd, G. M., and Friedman, J. M. (2005). Topographic mapping of VMH → arcuate nucleus microcircuits and their reorganization by fasting. Nat. Neurosci. 8, 1356-1363.
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1356-1363
-
-
Sternson, S.M.1
Shepherd, G.M.2
Friedman, J.M.3
-
96
-
-
34247616021
-
Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia
-
Tong, Q., Ye, C., McCrimmon, R. J., Dhillon, H., Choi, B., Kramer, M. D., et al. (2007). Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metab. 5, 383-393.
-
(2007)
Cell Metab.
, vol.5
, pp. 383-393
-
-
Tong, Q.1
Ye, C.2
McCrimmon, R.J.3
Dhillon, H.4
Choi, B.5
Kramer, M.D.6
-
97
-
-
50249120768
-
Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
-
Tong, Q., Ye, C. P., Jones, J. E., Elmquist, J. K., and Lowell, B. B. (2008). Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance. Nat. Neurosci. 11, 998-1000.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 998-1000
-
-
Tong, Q.1
Ye, C.P.2
Jones, J.E.3
Elmquist, J.K.4
Lowell, B.B.5
-
98
-
-
0031662163
-
A frameshift mutation in human MC4R is associated with a dominant form of obesity
-
Vaisse, C., Clement, K., Guy-Grand, B., and Froguel, P. (1998). A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat. Genet. 20, 113-114.
-
(1998)
Nat. Genet.
, vol.20
, pp. 113-114
-
-
Vaisse, C.1
Clement, K.2
Guy-Grand, B.3
Froguel, P.4
-
99
-
-
65549091103
-
Neuromedin B and gastrin-releasing peptide excite arcuate nucleus neuropeptide Y neurons in a novel transgenic mouse expressing strong Renilla green fluorescent protein in NPY neurons
-
Van Den Pol, A. N., Yao, Y., Fu, L. Y., Foo, K., Huang, H., Coppari, R., et al. (2009). Neuromedin B and gastrin-releasing peptide excite arcuate nucleus neuropeptide Y neurons in a novel transgenic mouse expressing strong Renilla green fluorescent protein in NPY neurons. J. Neurosci. 29, 4622-4639.
-
(2009)
J. Neurosci.
, vol.29
, pp. 4622-4639
-
-
Van Den Pol, A.N.1
Yao, Y.2
Fu, L.Y.3
Foo, K.4
Huang, H.5
Coppari, R.6
-
100
-
-
79960190012
-
Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons
-
Vong, L., Ye, C., Yang, Z., Choi, B., Chua, S. Jr., and Lowell, B. B. (2011). Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons. Neuron 71, 142-154.
-
(2011)
Neuron
, vol.71
, pp. 142-154
-
-
Vong, L.1
Ye, C.2
Yang, Z.3
Choi, B.4
Chua, Jr.S.5
Lowell, B.B.6
-
101
-
-
3242765290
-
The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides
-
Wang, R., Liu, X., Hentges, S. T., Dunn-Meynell, A. A., Levin, B. E., Wang, W., et al. (2004). The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides. Diabetes 53, 1959-1965.
-
(2004)
Diabetes
, vol.53
, pp. 1959-1965
-
-
Wang, R.1
Liu, X.2
Hentges, S.T.3
Dunn-Meynell, A.A.4
Levin, B.E.5
Wang, W.6
-
102
-
-
0031909974
-
Abnormal heart rate regulation in GIRK4 knockout mice
-
Wickman, K., Nemec, J., Gendler, S. J., and Clapham, D. E. (1998). Abnormal heart rate regulation in GIRK4 knockout mice. Neuron 20, 103-114.
-
(1998)
Neuron
, vol.20
, pp. 103-114
-
-
Wickman, K.1
Nemec, J.2
Gendler, S.J.3
Clapham, D.E.4
-
103
-
-
84866705627
-
From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior
-
Williams, K. W., and Elmquist, J. K. (2012). From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior. Nat. Neurosci. 15, 1350-1355.
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 1350-1355
-
-
Williams, K.W.1
Elmquist, J.K.2
-
104
-
-
77249146406
-
Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons
-
Williams, K. W., Margatho, L. O., Lee, C. E., Choi, M., Lee, S., Scott, M. M., et al. (2010). Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons. J. Neurosci. 30, 2472-2479.
-
(2010)
J. Neurosci.
, vol.30
, pp. 2472-2479
-
-
Williams, K.W.1
Margatho, L.O.2
Lee, C.E.3
Choi, M.4
Lee, S.5
Scott, M.M.6
-
105
-
-
79951990905
-
Modulation of the central melanocortin system by leptin, insulin, and serotonin: co-ordinated actions in a dispersed neuronal network
-
Williams, K. W., Scott, M. M., and Elmquist, J. K. (2011a). Modulation of the central melanocortin system by leptin, insulin, and serotonin: co-ordinated actions in a dispersed neuronal network. Eur. J. Pharmacol. 660, 2-12.
-
(2011)
Eur. J. Pharmacol.
, vol.660
, pp. 2-12
-
-
Williams, K.W.1
Scott, M.M.2
Elmquist, J.K.3
-
106
-
-
80052935067
-
The acute effects of leptin require PI3K signaling in the hypothalamic ventral premammillary nucleus
-
Williams, K. W., Sohn, J. W., Donato, J. Jr., Lee, C. E., Zhao, J. J., Elmquist, J. K., et al. (2011b). The acute effects of leptin require PI3K signaling in the hypothalamic ventral premammillary nucleus. J. Neurosci. 31, 13147-13156.
-
(2011)
J. Neurosci.
, vol.31
, pp. 13147-13156
-
-
Williams, K.W.1
Sohn, J.W.2
Donato, Jr.J.3
Lee, C.E.4
Zhao, J.J.5
Elmquist, J.K.6
-
107
-
-
33745034786
-
Rapid inhibition of neural excitability in the nucleus tractus solitarii by leptin: implications for ingestive behaviour
-
Williams, K. W., and Smith, B. N. (2006). Rapid inhibition of neural excitability in the nucleus tractus solitarii by leptin: implications for ingestive behaviour. J. Physiol. 573, 395-412.
-
(2006)
J. Physiol.
, vol.573
, pp. 395-412
-
-
Williams, K.W.1
Smith, B.N.2
-
108
-
-
0018621289
-
Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons
-
Woods, S. C., Lotter, E. C., McKay, L. D., and Porte, D. Jr. (1979). Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature 282, 503-505.
-
(1979)
Nature
, vol.282
, pp. 503-505
-
-
Woods, S.C.1
Lotter, E.C.2
McKay, L.D.3
Porte, Jr.D.4
-
109
-
-
77956272001
-
International union of basic and clinical pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family
-
Wu, L. J., Sweet, T. B., and Clapham, D. E. (2010). International union of basic and clinical pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family. Pharmacol. Rev. 62, 381-404.
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 381-404
-
-
Wu, L.J.1
Sweet, T.B.2
Clapham, D.E.3
-
110
-
-
67549112681
-
Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation
-
Wu, Q., Boyle, M. P., and Palmiter, R. D. (2009). Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation. Cell 137, 1225-1234.
-
(2009)
Cell
, vol.137
, pp. 1225-1234
-
-
Wu, Q.1
Boyle, M.P.2
Palmiter, R.D.3
-
111
-
-
84859215897
-
Deciphering a neuronal circuit that mediates appetite
-
Wu, Q., Clark, M. S., and Palmiter, R. D. (2012). Deciphering a neuronal circuit that mediates appetite. Nature 483, 594-597.
-
(2012)
Nature
, vol.483
, pp. 594-597
-
-
Wu, Q.1
Clark, M.S.2
Palmiter, R.D.3
-
112
-
-
78650191226
-
5-HT(2C)Rs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver
-
Xu, Y., Berglund, E. D., Sohn, J. W., Holland, W. L., Chuang, J. C., Fukuda, M., et al. (2010). 5-HT(2C)Rs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nat. Neurosci. 13, 1457-1459.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1457-1459
-
-
Xu, Y.1
Berglund, E.D.2
Sohn, J.W.3
Holland, W.L.4
Chuang, J.C.5
Fukuda, M.6
-
113
-
-
56349145180
-
5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis
-
Xu, Y., Jones, J. E., Kohno, D., Williams, K. W., Lee, C. E., Choi, M. J., et al. (2008). 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. Neuron 60, 582-589.
-
(2008)
Neuron
, vol.60
, pp. 582-589
-
-
Xu, Y.1
Jones, J.E.2
Kohno, D.3
Williams, K.W.4
Lee, C.E.5
Choi, M.J.6
-
114
-
-
84864927001
-
Rapamycin ameliorates age-dependent obesity associated with increased mtor signaling in hypothalamic POMC neurons
-
Yang, S. B., Tien, A. C., Boddupalli, G., Xu, A. W., Jan, Y. N., and Jan, L. Y. (2012). Rapamycin ameliorates age-dependent obesity associated with increased mtor signaling in hypothalamic POMC neurons. Neuron 75, 425-436.
-
(2012)
Neuron
, vol.75
, pp. 425-436
-
-
Yang, S.B.1
Tien, A.C.2
Boddupalli, G.3
Xu, A.W.4
Jan, Y.N.5
Jan, L.Y.6
-
115
-
-
80052922112
-
Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop
-
Yang, Y., Atasoy, D., Su, H. H., and Sternson, S. M. (2011). Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop. Cell 146, 992-1003.
-
(2011)
Cell
, vol.146
, pp. 992-1003
-
-
Yang, Y.1
Atasoy, D.2
Su, H.H.3
Sternson, S.M.4
-
116
-
-
0031668219
-
A frameshift mutation in MC4R associated with dominantly inherited human obesity
-
Yeo, G. S., Farooqi, I. S., Aminian, S., Halsall, D. J., Stanhope, R. G., and O'Rahilly, S. (1998). A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nat. Genet. 20, 111-112.
-
(1998)
Nat. Genet.
, vol.20
, pp. 111-112
-
-
Yeo, G.S.1
Farooqi, I.S.2
Aminian, S.3
Halsall, D.J.4
Stanhope, R.G.5
O'Rahilly, S.6
-
117
-
-
0033556338
-
Cell-type specific expression of ATP-sensitive potassium channels in the rat hippocampus
-
Zawar, C., Plant, T. D., Schirra, C., Konnerth, A., and Neumcke, B. (1999). Cell-type specific expression of ATP-sensitive potassium channels in the rat hippocampus. J. Physiol. 514(Pt 2), 327-341.
-
(1999)
J. Physiol.
, vol.514
, Issue.PART 2
, pp. 327-341
-
-
Zawar, C.1
Plant, T.D.2
Schirra, C.3
Konnerth, A.4
Neumcke, B.5
-
118
-
-
84875656935
-
Direct inhibition of arcuate POMC neurons- a potential mechanism for the orexigenic actions of dynorphin
-
Zhang, X., and Van Den Pol, A. N. (2013). Direct inhibition of arcuate POMC neurons- a potential mechanism for the orexigenic actions of dynorphin. J. Physiol. 591, 1731-1747.
-
(2013)
J. Physiol.
, vol.591
, pp. 1731-1747
-
-
Zhang, X.1
Van Den Pol, A.N.2
-
119
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M. (1994). Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
120
-
-
0036321620
-
A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding
-
Zhao, A. Z., Huan, J. N., Gupta, S., Pal, R., and Sahu, A. (2002). A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding. Nat. Neurosci. 5, 727-728.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 727-728
-
-
Zhao, A.Z.1
Huan, J.N.2
Gupta, S.3
Pal, R.4
Sahu, A.5
|