메뉴 건너뛰기




Volumn 71, Issue 3, 2011, Pages 488-497

Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; BACLOFEN; LEPTIN; PROOPIOMELANOCORTIN; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL C;

EID: 79961180328     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2011.06.012     Document Type: Article
Times cited : (164)

References (50)
  • 2
    • 77954633777 scopus 로고    scopus 로고
    • Drug management of obesity-efficacy versus safety
    • Astrup A. Drug management of obesity-efficacy versus safety. N. Engl. J. Med. 2010, 363:288-290.
    • (2010) N. Engl. J. Med. , vol.363 , pp. 288-290
    • Astrup, A.1
  • 4
    • 17644428076 scopus 로고    scopus 로고
    • Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons
    • Chen X., Johnston D. Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons. J. Neurosci. 2005, 25:3787-3792.
    • (2005) J. Neurosci. , vol.25 , pp. 3787-3792
    • Chen, X.1    Johnston, D.2
  • 10
    • 0038722027 scopus 로고    scopus 로고
    • D3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons
    • Davila V., Yan Z., Craciun L.C., Logothetis D., Sulzer D. D3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons. J. Neurosci. 2003, 23:5693-5697.
    • (2003) J. Neurosci. , vol.23 , pp. 5693-5697
    • Davila, V.1    Yan, Z.2    Craciun, L.C.3    Logothetis, D.4    Sulzer, D.5
  • 12
    • 1642285042 scopus 로고    scopus 로고
    • Contributions of 5-HT2C receptors to multiple actions of central serotonin systems
    • Giorgetti M., Tecott L.H. Contributions of 5-HT2C receptors to multiple actions of central serotonin systems. Eur. J. Pharmacol. 2004, 488:1-9.
    • (2004) Eur. J. Pharmacol. , vol.488 , pp. 1-9
    • Giorgetti, M.1    Tecott, L.H.2
  • 15
    • 0030025724 scopus 로고    scopus 로고
    • Cloning of a Xenopus laevis inwardly rectifying K+ channel subunit that permits GIRK1 expression of IKACh currents in oocytes
    • Hedin K.E., Lim N.F., Clapham D.E. Cloning of a Xenopus laevis inwardly rectifying K+ channel subunit that permits GIRK1 expression of IKACh currents in oocytes. Neuron 1996, 16:423-429.
    • (1996) Neuron , vol.16 , pp. 423-429
    • Hedin, K.E.1    Lim, N.F.2    Clapham, D.E.3
  • 22
    • 0029959793 scopus 로고    scopus 로고
    • Localization and interaction of epitope-tagged GIRK1 and CIR inward rectifier K+ channel subunits
    • Kennedy M.E., Nemec J., Clapham D.E. Localization and interaction of epitope-tagged GIRK1 and CIR inward rectifier K+ channel subunits. Neuropharmacology 1996, 35:831-839.
    • (1996) Neuropharmacology , vol.35 , pp. 831-839
    • Kennedy, M.E.1    Nemec, J.2    Clapham, D.E.3
  • 23
    • 0033593226 scopus 로고    scopus 로고
    • GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels
    • Kennedy M.E., Nemec J., Corey S., Wickman K., Clapham D.E. GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels. J. Biol. Chem. 1999, 274:2571-2582.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2571-2582
    • Kennedy, M.E.1    Nemec, J.2    Corey, S.3    Wickman, K.4    Clapham, D.E.5
  • 25
    • 0028934859 scopus 로고
    • The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K+-channel proteins
    • Krapivinsky G., Gordon E.A., Wickman K., Velimirović B., Krapivinsky L., Clapham D.E. The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K+-channel proteins. Nature 1995, 374:135-141.
    • (1995) Nature , vol.374 , pp. 135-141
    • Krapivinsky, G.1    Gordon, E.A.2    Wickman, K.3    Velimirović, B.4    Krapivinsky, L.5    Clapham, D.E.6
  • 26
    • 40849135860 scopus 로고    scopus 로고
    • Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors
    • Lam D.D., Przydzial M.J., Ridley S.H., Yeo G.S., Rochford J.J., O'Rahilly S., Heisler L.K. Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors. Endocrinology 2008, 149:1323-1328.
    • (2008) Endocrinology , vol.149 , pp. 1323-1328
    • Lam, D.D.1    Przydzial, M.J.2    Ridley, S.H.3    Yeo, G.S.4    Rochford, J.J.5    O'Rahilly, S.6    Heisler, L.K.7
  • 27
    • 77951498231 scopus 로고    scopus 로고
    • Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease
    • Lüscher C., Slesinger P.A. Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease. Nat. Rev. Neurosci. 2010, 11:301-315.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 301-315
    • Lüscher, C.1    Slesinger, P.A.2
  • 28
    • 0039357820 scopus 로고    scopus 로고
    • G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons
    • Lüscher C., Jan L.Y., Stoffel M., Malenka R.C., Nicoll R.A. G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron 1997, 19:687-695.
    • (1997) Neuron , vol.19 , pp. 687-695
    • Lüscher, C.1    Jan, L.Y.2    Stoffel, M.3    Malenka, R.C.4    Nicoll, R.A.5
  • 29
    • 0037186091 scopus 로고    scopus 로고
    • Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart
    • Ma D., Zerangue N., Raab-Graham K., Fried S.R., Jan Y.N., Jan L.Y. Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart. Neuron 2002, 33:715-729.
    • (2002) Neuron , vol.33 , pp. 715-729
    • Ma, D.1    Zerangue, N.2    Raab-Graham, K.3    Fried, S.R.4    Jan, Y.N.5    Jan, L.Y.6
  • 30
    • 0031721271 scopus 로고    scopus 로고
    • Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene
    • Nonogaki K., Strack A.M., Dallman M.F., Tecott L.H. Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene. Nat. Med. 1998, 4:1152-1156.
    • (1998) Nat. Med. , vol.4 , pp. 1152-1156
    • Nonogaki, K.1    Strack, A.M.2    Dallman, M.F.3    Tecott, L.H.4
  • 34
    • 79961179342 scopus 로고    scopus 로고
    • No F.D.A. approval for new diet pill. The New York Times, October 23, 2010, A27.
    • Pollack, A. (2010a). No F.D.A. approval for new diet pill. The New York Times, October 23, 2010, A27. http://www.nytimes.com/2010/10/24/business/24obesity.html.
    • (2010)
    • Pollack, A.1
  • 35
    • 79961178991 scopus 로고    scopus 로고
    • F.D.A. rejects Qnexa, a third weight-loss drug. The New York Times, October 28, 2010, A1.
    • Pollack, A. (2010b). F.D.A. rejects Qnexa, a third weight-loss drug. The New York Times, October 28, 2010, A1. http://www.nytimes.com/2010/10/29/health/policy/29drug.html.
    • (2010)
    • Pollack, A.1
  • 36
    • 34748903427 scopus 로고    scopus 로고
    • Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females
    • Qiu J., Xue C., Bosch M.A., Murphy J.G., Fan W., Rønnekleiv O.K., Kelly M.J. Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females. Mol. Pharmacol. 2007, 72:885-896.
    • (2007) Mol. Pharmacol. , vol.72 , pp. 885-896
    • Qiu, J.1    Xue, C.2    Bosch, M.A.3    Murphy, J.G.4    Fan, W.5    Rønnekleiv, O.K.6    Kelly, M.J.7
  • 37
    • 75349092316 scopus 로고    scopus 로고
    • Leptin excites proopiomelanocortin neurons via activation of TRPC channels
    • Qiu J., Fang Y., Rønnekleiv O.K., Kelly M.J. Leptin excites proopiomelanocortin neurons via activation of TRPC channels. J. Neurosci. 2010, 30:1560-1565.
    • (2010) J. Neurosci. , vol.30 , pp. 1560-1565
    • Qiu, J.1    Fang, Y.2    Rønnekleiv, O.K.3    Kelly, M.J.4
  • 41
    • 77954635020 scopus 로고    scopus 로고
    • Multicenter, placebo-controlled trial of lorcaserin for weight management
    • Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM) Study Group
    • Smith S.R., Weissman N.J., Anderson C.M., Sanchez M., Chuang E., Stubbe S., Bays H., Shanahan W.R. Multicenter, placebo-controlled trial of lorcaserin for weight management. N. Engl. J. Med. 2010, 363:245-256. Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM) Study Group.
    • (2010) N. Engl. J. Med. , vol.363 , pp. 245-256
    • Smith, S.R.1    Weissman, N.J.2    Anderson, C.M.3    Sanchez, M.4    Chuang, E.5    Stubbe, S.6    Bays, H.7    Shanahan, W.R.8
  • 42
    • 0035051978 scopus 로고    scopus 로고
    • TRPC1 and TRPC5 form a novel cation channel in mammalian brain
    • Strübing C., Krapivinsky G., Krapivinsky L., Clapham D.E. TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Neuron 2001, 29:645-655.
    • (2001) Neuron , vol.29 , pp. 645-655
    • Strübing, C.1    Krapivinsky, G.2    Krapivinsky, L.3    Clapham, D.E.4
  • 44
    • 50249120768 scopus 로고    scopus 로고
    • Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
    • Tong Q., Ye C.P., Jones J.E., Elmquist J.K., Lowell B.B. Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance. Nat. Neurosci. 2008, 11:998-1000.
    • (2008) Nat. Neurosci. , vol.11 , pp. 998-1000
    • Tong, Q.1    Ye, C.P.2    Jones, J.E.3    Elmquist, J.K.4    Lowell, B.B.5
  • 46
    • 0032962859 scopus 로고    scopus 로고
    • Reduced satiating effect of d-fenfluramine in serotonin 5-HT2C receptor mutant mice
    • Vickers S.P., Clifton P.G., Dourish C.T., Tecott L.H. Reduced satiating effect of d-fenfluramine in serotonin 5-HT2C receptor mutant mice. Psychopharmacology (Berl.) 1999, 143:309-314.
    • (1999) Psychopharmacology (Berl.) , vol.143 , pp. 309-314
    • Vickers, S.P.1    Clifton, P.G.2    Dourish, C.T.3    Tecott, L.H.4
  • 47
    • 77249146406 scopus 로고    scopus 로고
    • Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons
    • Williams K.W., Margatho L.O., Lee C.E., Choi M., Lee S., Scott M.M., Elias C.F., Elmquist J.K. Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons. J. Neurosci. 2010, 30:2472-2479.
    • (2010) J. Neurosci. , vol.30 , pp. 2472-2479
    • Williams, K.W.1    Margatho, L.O.2    Lee, C.E.3    Choi, M.4    Lee, S.5    Scott, M.M.6    Elias, C.F.7    Elmquist, J.K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.