Fasting activation of AgRP neurons requires NMDA receptors and involves spinogenesis and increased excitatory tone

Neuron

Volumn 73, Issue 3, 2012, Pages 511-522

  Liu, Tiemin ^a   Kong, Dong ^a   Shah, BhavikP ^a   Ye, Chianping ^a   Koda, Shuichi ^a,b   Saunders, Arpiar ^c   Ding, JunB ^c   Yang, Zongfang ^a   Sabatini, BernardoL ^c   Lowell, BradfordB ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b DAIICHI SANKYO CO   (Japan)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; AMPA RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; PROTEIN C FOS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY FAT; BODY WEIGHT; CONTROLLED STUDY; DENDRITIC SPINE; DEPOLARIZATION; ENERGY BALANCE; EXCITATION; EXCITATORY POSTSYNAPTIC POTENTIAL; FOOD DEPRIVATION; FOOD INTAKE; GENE EXPRESSION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SPINOGENESIS; SYNAPTIC TRANSMISSION; SYNAPTOGENESIS;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; AGE FACTORS; AGOUTI-RELATED PROTEIN; ANIMALS; BODY COMPOSITION; BRAIN; CARRIER PROTEINS; DENDRITIC SPINES; EATING; ENERGY METABOLISM; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; FASTING; FEMALE; GABA ANTAGONISTS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; MALE; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONS; NEUROPEPTIDE Y; PATCH-CLAMP TECHNIQUES; PICROTOXIN; PRO-OPIOMELANOCORTIN; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; TIME FACTORS;

EID: 84863012024     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2011.11.027     Document Type: Article

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