Surface derivatization state of polystyrene latex nanoparticles determines both their potency and their mechanism of causing human platelet aggregation in vitro

Toxicological Sciences

Volumn 119, Issue 2, 2011, Pages 359-368

  McGuinnes, Catherine ^a   Duffin, Rodger ^a   Brown, Simon ^a   Mills, Nicholas L ^a   Megson, Ian L ^b   MacNee, William ^a   Johnston, Shonna ^a   Lu, Sen Lin ^c   Tran, Lang ^d   Li, Rufia ^e   Wang, Xue ^e   Newby, David E ^a   Donaldson, Ken ^a,d  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF THE HIGHLANDS AND ISLANDS   (United Kingdom)

^c SHANGHAI UNIVERSITY   (China)

^d INSTITUTE OF OCCUPATIONAL MEDICINE   (United Kingdom)

^e UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Aggregation; Nanoparticles; Nanotoxicology; Platelets

Indexed keywords

LATEX; NANOPARTICLE; PHOSPHOLIPID; POLYSTYRENE;

ARTICLE; CONTAMINATION; CONTROLLED STUDY; DERIVATIZATION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE MEMBRANE; UPREGULATION;

EID: 78751699054     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq349     Document Type: Article

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