-
1
-
-
0035799120
-
The Meuse Valley fog of 1930: An air pollution disaster
-
Nemery B, Hoet PHM, Nemmar A. The Meuse Valley fog of 1930: an air pollution disaster. Lancet 2001; 357:704-708.
-
(2001)
Lancet
, vol.357
, pp. 704-708
-
-
Nemery, B.1
Hoet, P.H.M.2
Nemmar, A.3
-
2
-
-
50449141671
-
Mortality in the London fog incident
-
Logan WPD. Mortality in the London fog incident. Lancet 1953; 261:336-338.
-
(1953)
Lancet
, vol.261
, pp. 336-338
-
-
Logan, W.P.D.1
-
3
-
-
0037136933
-
Air pollution and health
-
Brunekreef B, Holgate ST. Air pollution and health. Lancet 2002; 360:1233-1242.
-
(2002)
Lancet
, vol.360
, pp. 1233-1242
-
-
Brunekreef, B.1
Holgate, S.T.2
-
4
-
-
0037736542
-
Particle characteristics responsible for effects on human lung epithelial cells
-
110; 2002
-
Aust AE, Ball JC, Hu AA, et al. Particle characteristics responsible for effects on human lung epithelial cells. HEI Research Report 110; 2002.
-
HEI Research Report
-
-
Aust, A.E.1
Ball, J.C.2
Hu, A.A.3
-
5
-
-
33745440031
-
-
Pope AC III, Dockery DW. Health effects of fine particulate air pollution: lines that connect. J Air Waste Manage Assoc 2006; 56:709-742. A very comprehensive review of more than 500 articles.
-
Pope AC III, Dockery DW. Health effects of fine particulate air pollution: lines that connect. J Air Waste Manage Assoc 2006; 56:709-742. A very comprehensive review of more than 500 articles.
-
-
-
-
6
-
-
17644389241
-
-
Lacasana M, Esplugues A, Ballester F. Exposure to ambient air pollution and prenatal and early childhood health effects. Eur J Epidemiol 2005; 20:183-199. This article reviews publications from 1999 to 2003, which have evaluated the possible impact of air pollution on the fetus and the first year of life.
-
Lacasana M, Esplugues A, Ballester F. Exposure to ambient air pollution and prenatal and early childhood health effects. Eur J Epidemiol 2005; 20:183-199. This article reviews publications from 1999 to 2003, which have evaluated the possible impact of air pollution on the fetus and the first year of life.
-
-
-
-
7
-
-
33745698683
-
Carbon in airway macrophages and lung function in children
-
Cross-sectional study using carbon in airway macrophages as exposure variable. This study is very original by using an internal marker of external exposure at an individual level
-
Kulkarni N, Pierse N, Rushton L, Grigg J. Carbon in airway macrophages and lung function in children. N Engl J Med 2006; 355:21-30. Cross-sectional study using carbon in airway macrophages as exposure variable. This study is very original by using an internal marker of external exposure at an individual level.
-
(2006)
N Engl J Med
, vol.355
, pp. 21-30
-
-
Kulkarni, N.1
Pierse, N.2
Rushton, L.3
Grigg, J.4
-
8
-
-
4444367099
-
The effect of air pollution on lung development from 10 to 18 years of age
-
Gauderman WJ, Avol E, Gilliland F, et al. The effect of air pollution on lung development from 10 to 18 years of age. N Engl J Med 2004; 351:1057-1067.
-
(2004)
N Engl J Med
, vol.351
, pp. 1057-1067
-
-
Gauderman, W.J.1
Avol, E.2
Gilliland, F.3
-
9
-
-
13444291580
-
Biology of diesel exhaust effects on respiratory function
-
Riedl M, Diaz-Sanchez D. Biology of diesel exhaust effects on respiratory function. J Allergy Clin Immunol 2005; 115:221-228.
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 221-228
-
-
Riedl, M.1
Diaz-Sanchez, D.2
-
10
-
-
0347948542
-
Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: Randomised, placebo-controlled crossover study
-
Gilliland FD, Li YF, Saxon A, Diaz-Sanchez D. Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study. Lancet 2004; 363:119-125.
-
(2004)
Lancet
, vol.363
, pp. 119-125
-
-
Gilliland, F.D.1
Li, Y.F.2
Saxon, A.3
Diaz-Sanchez, D.4
-
11
-
-
0036558481
-
Allergic susceptibility associated with diesel exhaust particle exposure: Clear as mud
-
Polosa R, Salvi S, Di Maria GU. Allergic susceptibility associated with diesel exhaust particle exposure: clear as mud. Arch Environ Health 2002; 57:188-193.
-
(2002)
Arch Environ Health
, vol.57
, pp. 188-193
-
-
Polosa, R.1
Salvi, S.2
Di Maria, G.U.3
-
12
-
-
0035891602
-
Acute effects of particulate air pollution on respiratory admissions: Results from Aphea 2 project: Air Pollution and Health: A European Approach
-
Atkinson RW, Anderson HR, Sunyer J, et al. Acute effects of particulate air pollution on respiratory admissions: results from Aphea 2 project: Air Pollution and Health: A European Approach. Am J Respir and Crit Care Med 2001; 164:1860-1866.
-
(2001)
Am J Respir and Crit Care Med
, vol.164
, pp. 1860-1866
-
-
Atkinson, R.W.1
Anderson, H.R.2
Sunyer, J.3
-
13
-
-
29644445833
-
Long-term air pollution exposure and living close to busy roads are associated with COPD in women
-
An original prospective investigation on the development of COPD in association with chronic air pollution
-
Schikowski T, Sugiri D, Ranft U, et al. Long-term air pollution exposure and living close to busy roads are associated with COPD in women. Respir Res 2005; 6:152. An original prospective investigation on the development of COPD in association with chronic air pollution.
-
(2005)
Respir Res
, vol.6
, pp. 152
-
-
Schikowski, T.1
Sugiri, D.2
Ranft, U.3
-
14
-
-
0027362097
-
An association between air pollution and mortality in six US cities
-
Dockery DW, Pope CA III, Xu X, et al. An association between air pollution and mortality in six US cities. N Engl J Med 1993; 329:1753-1759.
-
(1993)
N Engl J Med
, vol.329
, pp. 1753-1759
-
-
Dockery, D.W.1
Pope III, C.A.2
Xu, X.3
-
15
-
-
33646520596
-
Air pollution and risk of lung cancer in a prospective study in Europe
-
A European multicentre nested-case control study on the association between chronic traffic-related exposure and lung cancer risk
-
Vineis P, Hoek G, Krzyzanowski M, et al. Air pollution and risk of lung cancer in a prospective study in Europe. Int J Cancer 2006; 119:169-174. A European multicentre nested-case control study on the association between chronic traffic-related exposure and lung cancer risk.
-
(2006)
Int J Cancer
, vol.119
, pp. 169-174
-
-
Vineis, P.1
Hoek, G.2
Krzyzanowski, M.3
-
16
-
-
0032457372
-
Long-term concentrations of ambient air pollutants and incident lung cancer in California adults: Results from the AHSMOG study
-
Beeson WL, Abbey DA, Knutsen SF. Long-term concentrations of ambient air pollutants and incident lung cancer in California adults: results from the AHSMOG study. Environ Health Perspect 1998; 106:813-823.
-
(1998)
Environ Health Perspect
, vol.106
, pp. 813-823
-
-
Beeson, W.L.1
Abbey, D.A.2
Knutsen, S.F.3
-
17
-
-
0037029043
-
Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution
-
Pope CA, Burnett RT, Thun MJ, et al. Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA 2002; 287: 1132-1141.
-
(2002)
JAMA
, vol.287
, pp. 1132-1141
-
-
Pope, C.A.1
Burnett, R.T.2
Thun, M.J.3
-
18
-
-
0037136938
-
Association between mortality and indicators of traffic-related air pollution in the Netherlands: A cohort study
-
Hoek G, Brunekreef B, Goldbohm S, et al. Association between mortality and indicators of traffic-related air pollution in the Netherlands: a cohort study. Lancet 2002; 360:1203-1209.
-
(2002)
Lancet
, vol.360
, pp. 1203-1209
-
-
Hoek, G.1
Brunekreef, B.2
Goldbohm, S.3
-
19
-
-
0346030571
-
Lung cancer and air pollution: A 27 year follow up of 16209 Norwegian men
-
Nafstad P, Haheim LL, Oftedal B, et al. Lung cancer and air pollution: a 27 year follow up of 16209 Norwegian men. Thorax 2003; 58:1071-1076.
-
(2003)
Thorax
, vol.58
, pp. 1071-1076
-
-
Nafstad, P.1
Haheim, L.L.2
Oftedal, B.3
-
20
-
-
33846632684
-
Multifactor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions
-
6 September [Epub ahead of print, Shows a gene-environment interaction between polymorphisms of DNA repair and the distance of living from a major road
-
Manuguerra M, Matullo G, Veglia F, et al. Multifactor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions. Carcinogenesis 2006; 6 September [Epub ahead of print]. Shows a gene-environment interaction between polymorphisms of DNA repair and the distance of living from a major road.
-
(2006)
Carcinogenesis
-
-
Manuguerra, M.1
Matullo, G.2
Veglia, F.3
-
22
-
-
0033559427
-
Cytotoxicity and induction of proinflammatory cytokines from human monocytes exposed to fine (PM25) and coarse (PM10-25) in outdoor and indoor air
-
Moon C, Becker S. Cytotoxicity and induction of proinflammatory cytokines from human monocytes exposed to fine (PM25) and coarse (PM10-25) in outdoor and indoor air. Toxicol Appl Pharmacol 1999; 155:245-252.
-
(1999)
Toxicol Appl Pharmacol
, vol.155
, pp. 245-252
-
-
Moon, C.1
Becker, S.2
-
23
-
-
0031976240
-
Urban particle induced apoptosis and phenotype shifts in human alveolar machropages
-
Holian A, Hamilton RF, Morandi MT, et al. Urban particle induced apoptosis and phenotype shifts in human alveolar machropages. Environ Health Perspect 1998; 106:127-132.
-
(1998)
Environ Health Perspect
, vol.106
, pp. 127-132
-
-
Holian, A.1
Hamilton, R.F.2
Morandi, M.T.3
-
24
-
-
0036422961
-
Surface components of airborne particulate matter induce macrophage apoptosis through scavenger receptors
-
Obot CJ, Morandi MT, Beebe TP, et al. Surface components of airborne particulate matter induce macrophage apoptosis through scavenger receptors. Toxicol Appl Pharmacol 2002; 184:98-106.
-
(2002)
Toxicol Appl Pharmacol
, vol.184
, pp. 98-106
-
-
Obot, C.J.1
Morandi, M.T.2
Beebe, T.P.3
-
25
-
-
0036057473
-
Biologic effects induced in vitro by PM10 from three different zones of Mexico City
-
Alfaro-Moreno E, Martínez L, García-Cuellar C, et al. Biologic effects induced in vitro by PM10 from three different zones of Mexico City. Environ Health Perspect 2002; 110:715-720.
-
(2002)
Environ Health Perspect
, vol.110
, pp. 715-720
-
-
Alfaro-Moreno, E.1
Martínez, L.2
García-Cuellar, C.3
-
26
-
-
0041973856
-
Proinflammatory and cytotoxic effects of Mexico City air pollution particulate matter in vitro are dependent on particle size and composition
-
Osornio-Vargas AR, Bonner JC, Alfaro-Moreno E, et al. Proinflammatory and cytotoxic effects of Mexico City air pollution particulate matter in vitro are dependent on particle size and composition. Environ Health Perspect 2003; 111:1289-1293.
-
(2003)
Environ Health Perspect
, vol.111
, pp. 1289-1293
-
-
Osornio-Vargas, A.R.1
Bonner, J.C.2
Alfaro-Moreno, E.3
-
27
-
-
0032185780
-
Induction of the lung myofibroblast PDGF receptor system by urban ambient particles from Mexico City
-
Bonner JC, Rice AB, Lindroos PM, et al. Induction of the lung myofibroblast PDGF receptor system by urban ambient particles from Mexico City. Am J Respir Cell Mol Biol 1998; 19:672-680.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 672-680
-
-
Bonner, J.C.1
Rice, A.B.2
Lindroos, P.M.3
-
28
-
-
0028972062
-
Mutagenicity assessment of airborne particles in Mexico City
-
Villalobos R, Blanco S, Gomez S. Mutagenicity assessment of airborne particles in Mexico City. Atmospheric Environ 1995; 29:517-524.
-
(1995)
Atmospheric Environ
, vol.29
, pp. 517-524
-
-
Villalobos, R.1
Blanco, S.2
Gomez, S.3
-
29
-
-
33846292606
-
DNA damage induced by PM10 from different zones of Mexico City
-
García-Cuellar C, Alfaro-Moreno E, Martínez-Romero F, et al. DNA damage induced by PM10 from different zones of Mexico City. Ann Occup Hygiene 2002; 46 (Suppl 1):425-428.
-
(2002)
Ann Occup Hygiene
, vol.46
, Issue.SUPPL. 1
, pp. 425-428
-
-
García-Cuellar, C.1
Alfaro-Moreno, E.2
Martínez-Romero, F.3
-
30
-
-
33646118753
-
-
Wise H, Balharry D, Reynolds LJ, et al. Conventional and toxicogenomic assessment of the acute pulmonary damage induced by the instillation of Cardiff PM10 into the rat lung. Sci Total Environ 2006; 360:60-67. This paper shows that 3 days after instillation, rats present a mild oedematous response.
-
Wise H, Balharry D, Reynolds LJ, et al. Conventional and toxicogenomic assessment of the acute pulmonary damage induced by the instillation of Cardiff PM10 into the rat lung. Sci Total Environ 2006; 360:60-67. This paper shows that 3 days after instillation, rats present a mild oedematous response.
-
-
-
-
31
-
-
16844368155
-
-
Dagher Z, Garçon G, Gosset P, et al. Pro-inflammatory effects of Dunkerque City air pollution particulate matter 2.5 in human epithelial lung cells (L132) in culture. J Appl Toxicol 2005; 25:166-175. In this paper, the authors present an evaluation of urban particle effects in a human lung epithelial cell line under proliferative conditions, showing that the proinflammatory response lasts up to 3 days after exposure
-
Dagher Z, Garçon G, Gosset P, et al. Pro-inflammatory effects of Dunkerque City air pollution particulate matter 2.5 in human epithelial lung cells (L132) in culture. J Appl Toxicol 2005; 25:166-175. In this paper, the authors present an evaluation of urban particle effects in a human lung epithelial cell line under proliferative conditions, showing that the proinflammatory response lasts up to 3 days after exposure.
-
-
-
-
32
-
-
33746770098
-
Ultrafine particles cause cytoskeletal dysfunctions in macrophages: Role of intracellular calcium
-
This study gives evidence of the mechanism related to cytoskeletal dysfunction in macrophages exposed to particulate matter
-
Möller W, Brown DM, Kreyling WG, Stone V. Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium. Particle Fibre Toxicol 2005; 2:7. This study gives evidence of the mechanism related to cytoskeletal dysfunction in macrophages exposed to particulate matter.
-
(2005)
Particle Fibre Toxicol
, vol.2
, pp. 7
-
-
Möller, W.1
Brown, D.M.2
Kreyling, W.G.3
Stone, V.4
-
33
-
-
33745231134
-
-
Mamessier E, Nieves A, Vervloet D, Magnan A. Diesel exhaust particles enhance T-cell activation in severe asthmatics. Allergy 2006; 61:581-588. This paper provides evidence of the possible mechanism involved in exacerbation of asthma related to particulate matter exposure.
-
Mamessier E, Nieves A, Vervloet D, Magnan A. Diesel exhaust particles enhance T-cell activation in severe asthmatics. Allergy 2006; 61:581-588. This paper provides evidence of the possible mechanism involved in exacerbation of asthma related to particulate matter exposure.
-
-
-
-
34
-
-
2942724471
-
Contribution of Il-1β and TNFα to the initiation of the peripheral lung response to atmospheric particulates (PM10)
-
Ishii H, Fuji T, Hogg JC, et al. Contribution of Il-1β and TNFα to the initiation of the peripheral lung response to atmospheric particulates (PM10). Am J Physiol Lung Cell Mol Physiol 2004; 287:L176-L183.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Ishii, H.1
Fuji, T.2
Hogg, J.C.3
-
35
-
-
26244448915
-
Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment
-
This is a study presenting the interactions between macrophages and epithelial cells in relation to the cytokine secretion profile after exposure to particulate matter
-
Ishii H, Hayashi S, Hogg JC, et al. Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment. Respir Res 2005; 6:87. This is a study presenting the interactions between macrophages and epithelial cells in relation to the cytokine secretion profile after exposure to particulate matter.
-
(2005)
Respir Res
, vol.6
, pp. 87
-
-
Ishii, H.1
Hayashi, S.2
Hogg, J.C.3
-
36
-
-
13444253948
-
-
Becker S, Dailey L, Soukup JM, et al. TLR-2 is involved in airway epithelial cell response to air pollution particles. Toxicol Appl Pharmacol 2005; 203:45-52. This is an excellent study providing strong evidence of the role of TLR-2 in the cellular response to particulate matter.
-
Becker S, Dailey L, Soukup JM, et al. TLR-2 is involved in airway epithelial cell response to air pollution particles. Toxicol Appl Pharmacol 2005; 203:45-52. This is an excellent study providing strong evidence of the role of TLR-2 in the cellular response to particulate matter.
-
-
-
-
37
-
-
0036847266
-
Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles
-
Becker S, Fenton MJ, Soukup JM. Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles. Am J Respir Cell Mol Biol 2002; 27:611-618.
-
(2002)
Am J Respir Cell Mol Biol
, vol.27
, pp. 611-618
-
-
Becker, S.1
Fenton, M.J.2
Soukup, J.M.3
-
38
-
-
33646727601
-
Cytokine release from alveolar macrophages exposed to ambient particulate matter: Heterogeneity in relation to size, city and season
-
Describes the differences of in-vitro effects of particles related to the city in which the particles were collected
-
Hetland RB, Cassee FR, Låg M, et al. Cytokine release from alveolar macrophages exposed to ambient particulate matter: heterogeneity in relation to size, city and season. Particle Fibre Toxicol 2005; 2:4. Describes the differences of in-vitro effects of particles related to the city in which the particles were collected.
-
(2005)
Particle Fibre Toxicol
, vol.2
, pp. 4
-
-
Hetland, R.B.1
Cassee, F.R.2
Låg, M.3
-
39
-
-
33644769277
-
Correlation of in vitro cytokine responses with the chemical composition of soil-derived particulate matter
-
An excellent article presenting the role of composition on the biologic effect of soil-derived particulate matter
-
Veranth JM, Moss TA, Chow JC, et al. Correlation of in vitro cytokine responses with the chemical composition of soil-derived particulate matter. Environ Health Perspect 2006; 114:341-349. An excellent article presenting the role of composition on the biologic effect of soil-derived particulate matter.
-
(2006)
Environ Health Perspect
, vol.114
, pp. 341-349
-
-
Veranth, J.M.1
Moss, T.A.2
Chow, J.C.3
-
40
-
-
33846583243
-
Relations between PM10 composition and cell toxicity: A multivariate and graphical approach
-
in press
-
Rosas-Pérez I, Serrano J, Alfaro-Moreno E, et al. Relations between PM10 composition and cell toxicity: a multivariate and graphical approach. Chemosphere (in press).
-
Chemosphere
-
-
Rosas-Pérez, I.1
Serrano, J.2
Alfaro-Moreno, E.3
-
41
-
-
23844525370
-
Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress
-
An excellent article that deals with differences in composition related to seasonal variations and different biologic effects
-
Becker S, Dailey L, Soukup JM, et al. Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress. Environ Health Perspectives 2005; 113:1032-1038. An excellent article that deals with differences in composition related to seasonal variations and different biologic effects.
-
(2005)
Environ Health Perspectives
, vol.113
, pp. 1032-1038
-
-
Becker, S.1
Dailey, L.2
Soukup, J.M.3
-
42
-
-
8744239308
-
Relationship between composition and toxicity of motor vehicle emission samples
-
McDonald JD, Eide I, Seagrave J, et al. Relationship between composition and toxicity of motor vehicle emission samples. Environ Health Perspec 2004; 112:1527-1538.
-
(2004)
Environ Health Perspec
, vol.112
, pp. 1527-1538
-
-
McDonald, J.D.1
Eide, I.2
Seagrave, J.3
-
43
-
-
28244481785
-
Oxidative stress-induced DNA damage by particulate air pollution
-
A comprehensive review of the evidence that correlates particulate matter with DNA damage
-
Risom L, Møller P, Loft S. Oxidative stress-induced DNA damage by particulate air pollution. Mutation Res 2005; 592:119-137. A comprehensive review of the evidence that correlates particulate matter with DNA damage.
-
(2005)
Mutation Res
, vol.592
, pp. 119-137
-
-
Risom, L.1
Møller, P.2
Loft, S.3
-
44
-
-
27744555500
-
Personal exposure to ultrafine particles and oxidative DNA damage
-
A very good article presenting evidence that particulate matter correlates with oxidative stress and DNA damage, but other pollutants do not
-
Vinzents PS, Møller P, Sørensen M, et al. Personal exposure to ultrafine particles and oxidative DNA damage. Environ Health Perspect 2005; 113:1485-1490. A very good article presenting evidence that particulate matter correlates with oxidative stress and DNA damage, but other pollutants do not.
-
(2005)
Environ Health Perspect
, vol.113
, pp. 1485-1490
-
-
Vinzents, P.S.1
Møller, P.2
Sørensen, M.3
-
45
-
-
18444406321
-
Genotoxicity of size-fractionated samples of urban particulate matter
-
The data presented in this article strongly indicate that the genotoxic effects of particulate matter may be related to interactions among particulate matter components. This is concluded considering that fractions isolated from the total particles had a less strong genotoxic effect
-
Healey K, Lingard JJN, Tomlin S, et al. Genotoxicity of size-fractionated samples of urban particulate matter. Environ Mol Mutagen 2005; 45:380-387. The data presented in this article strongly indicate that the genotoxic effects of particulate matter may be related to interactions among particulate matter components. This is concluded considering that fractions isolated from the total particles had a less strong genotoxic effect.
-
(2005)
Environ Mol Mutagen
, vol.45
, pp. 380-387
-
-
Healey, K.1
Lingard, J.J.N.2
Tomlin, S.3
-
46
-
-
28944440877
-
Genotoxic and mutagenic activity of environmental air samples from different rural, urban and industrial sites in Flanders
-
This study presents evidence of the mutagenic effects of air samples using the Ames test
-
Du Four VA, Janssen CR, Brits E, Larebeke NV. Genotoxic and mutagenic activity of environmental air samples from different rural, urban and industrial sites in Flanders. Belgium Mutation Res 2005; 588:106-117. This study presents evidence of the mutagenic effects of air samples using the Ames test.
-
(2005)
Belgium Mutation Res
, vol.588
, pp. 106-117
-
-
Du Four, V.A.1
Janssen, C.R.2
Brits, E.3
Larebeke, N.V.4
-
47
-
-
33748993408
-
Air pollution: To the heart of the matter
-
Brief overview of the air pollution epidemiology
-
Nawrot TS, Nemmar A, Nemery B. Air pollution: to the heart of the matter. Eur Heart J 2006; 27:2269-2271. Brief overview of the air pollution epidemiology.
-
(2006)
Eur Heart J
, vol.27
, pp. 2269-2271
-
-
Nawrot, T.S.1
Nemmar, A.2
Nemery, B.3
-
48
-
-
33846567881
-
Stronger associations between daily mortality and fine particulate air pollution in summer than in winter: Evidence from a heavily polluted region in western Europe
-
in press
-
Nawrot TS, Torfs R, Fierens F, et al. Stronger associations between daily mortality and fine particulate air pollution in summer than in winter: evidence from a heavily polluted region in western Europe. J Epidemiol Comm Health (in press).
-
J Epidemiol Comm Health
-
-
Nawrot, T.S.1
Torfs, R.2
Fierens, F.3
-
49
-
-
0034823916
-
Identification of persons with cardiorespiratory conditions who are at risk of dying from the acute effects of ambient air particles
-
Goldberg MS, Burnett RT, Bailar JC, et al. Identification of persons with cardiorespiratory conditions who are at risk of dying from the acute effects of ambient air particles. Environ Health Perspect 2001; 109 (Suppl 4):487-494.
-
(2001)
Environ Health Perspect
, vol.109
, Issue.SUPPL. 4
, pp. 487-494
-
-
Goldberg, M.S.1
Burnett, R.T.2
Bailar, J.C.3
-
50
-
-
30444440046
-
Glutathione-S-transferase M1, obesity, statins, and autonomic effects of particles: Gene-by-drug-by- environment interaction
-
Original concept that shows in an epidemiological context the role of the susceptibility to inflammation as an effect modifier in the association between heart rate variability and air pollution
-
Schwartz J, Park SK, O'Neill MS, et al. Glutathione-S-transferase M1, obesity, statins, and autonomic effects of particles: gene-by-drug-by- environment interaction. Am J Respir Crit Care Med 2005; 172:1529-1533. Original concept that shows in an epidemiological context the role of the susceptibility to inflammation as an effect modifier in the association between heart rate variability and air pollution.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 1529-1533
-
-
Schwartz, J.1
Park, S.K.2
O'Neill, M.S.3
-
51
-
-
0347086147
-
Cardiovascular mortality and long-term exposure to particulate air pollution: Epidemiological evidence of general pathophysiological pathways of disease
-
Pope CA III, Burnett RT, Thurston GD, et al. Cardiovascular mortality and long-term exposure to particulate air pollution: epidemiological evidence of general pathophysiological pathways of disease. Circulation 2004; 109: 71-77.
-
(2004)
Circulation
, vol.109
, pp. 71-77
-
-
Pope III, C.A.1
Burnett, R.T.2
Thurston, G.D.3
-
52
-
-
33746902053
-
Translocation of inhaled ultrafine manganese oxide particles to the central nervous system
-
This is a very original study demonstrating that the olfactory neuronal pathway is efficient for translocating inhaled UFPs to the CNS and that this can result in inflammatory changes
-
Elder A, Gelein R, Silva V, et al. Translocation of inhaled ultrafine manganese oxide particles to the central nervous system. Environ Health Perspec 2006; 114:1172-1178. This is a very original study demonstrating that the olfactory neuronal pathway is efficient for translocating inhaled UFPs to the CNS and that this can result in inflammatory changes.
-
(2006)
Environ Health Perspec
, vol.114
, pp. 1172-1178
-
-
Elder, A.1
Gelein, R.2
Silva, V.3
-
53
-
-
17144472459
-
Translocation of inhaled ultrafine particles to the brain
-
Oberdorster G, Sharp Z, Atudorei V, et al. Translocation of inhaled ultrafine particles to the brain. Inhal Toxicol 2004; 16:437-445.
-
(2004)
Inhal Toxicol
, vol.16
, pp. 437-445
-
-
Oberdorster, G.1
Sharp, Z.2
Atudorei, V.3
-
54
-
-
0037175036
-
Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmonary organs is size dependent but very low
-
Kreyling W, Semmler M, Erbe F, et al. Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmonary organs is size dependent but very low. J Toxicol Environ Health A 2002; 65:1513-1530.
-
(2002)
J Toxicol Environ Health A
, vol.65
, pp. 1513-1530
-
-
Kreyling, W.1
Semmler, M.2
Erbe, F.3
-
55
-
-
0035508412
-
Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster
-
Nemmar A, Vanbilloen H, Hoylaerts MF, et al. Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster. Am J Respir Crit Care Med 2001; 164:1665-1668.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1665-1668
-
-
Nemmar, A.1
Vanbilloen, H.2
Hoylaerts, M.F.3
-
56
-
-
0037174958
-
Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats
-
Oberdorster G, Sharp Z, Atudorei V, et al. Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J Toxicol Environ Health A 2002; 65:1531-1543.
-
(2002)
J Toxicol Environ Health A
, vol.65
, pp. 1531-1543
-
-
Oberdorster, G.1
Sharp, Z.2
Atudorei, V.3
-
57
-
-
0034837422
-
Pulmonary and systemic distribution of inhaled ultrafine silver particles in rats
-
Takenaka S, Karg E, Roth C, et al. Pulmonary and systemic distribution of inhaled ultrafine silver particles in rats. Environ Health Perspec 2001; 109 (Suppl 4):547-551.
-
(2001)
Environ Health Perspec
, vol.109
, Issue.SUPPL. 4
, pp. 547-551
-
-
Takenaka, S.1
Karg, E.2
Roth, C.3
-
58
-
-
27744533436
-
-
Geiser M, Rothen-Rutishauser B, Kapp N, et al. Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environ Health Perspect 2005; 113:1555-1560. This study reports that inhaled ultrafine titanium dioxide particles can be found on the luminal side of airways and alveoli, in all major lung tissue compartments and cells, and within capillaries, and the particle uptake in vitro into cells does not occur by endocytosis, but by diffusion or adhesive interactions.
-
Geiser M, Rothen-Rutishauser B, Kapp N, et al. Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environ Health Perspect 2005; 113:1555-1560. This study reports that inhaled ultrafine titanium dioxide particles can be found on the luminal side of airways and alveoli, in all major lung tissue compartments and cells, and within capillaries, and the particle uptake in vitro into cells does not occur by endocytosis, but by diffusion or adhesive interactions.
-
-
-
-
59
-
-
2542569630
-
Electron energy loss spectroscopy for analysis of inhaled ultrafine particles in rat lungs
-
Kapp N, Kreyling W, Schulz H, et al. Electron energy loss spectroscopy for analysis of inhaled ultrafine particles in rat lungs. Microsc Res Tech 2004; 63:298-305.
-
(2004)
Microsc Res Tech
, vol.63
, pp. 298-305
-
-
Kapp, N.1
Kreyling, W.2
Schulz, H.3
-
60
-
-
1842869151
-
Evidence that exogenous substances can be phagocytized by alveolar epithelial cells and transported into blood capillaries
-
Kato T, Yashiro T, Murata Y, et al. Evidence that exogenous substances can be phagocytized by alveolar epithelial cells and transported into blood capillaries. Cell Tissue Res 2003; 311:47-51.
-
(2003)
Cell Tissue Res
, vol.311
, pp. 47-51
-
-
Kato, T.1
Yashiro, T.2
Murata, Y.3
-
61
-
-
0035860620
-
Microsphere translocation and immunopotentiation in systemic tissues following intranasal administration
-
Eyles JE, Bramwell VW, Williamsson ED, Alpar HO. Microsphere translocation and immunopotentiation in systemic tissues following intranasal administration. Vaccine 2001; 19:4732-4742.
-
(2001)
Vaccine
, vol.19
, pp. 4732-4742
-
-
Eyles, J.E.1
Bramwell, V.W.2
Williamsson, E.D.3
Alpar, H.O.4
-
62
-
-
33144476650
-
The influence of hydrogen peroxide and histamine on lung permeability and translocation of iridium nanoparticles in the isolated perfused rat lung
-
This study reports that permeability of the lung barrier to UFPs is controlled both at the epithelial and endothelial level, and is influenced by the inflammation
-
Meiring J, Borm PJA, Bagate K, et al. The influence of hydrogen peroxide and histamine on lung permeability and translocation of iridium nanoparticles in the isolated perfused rat lung. Part Fibre Toxicol 2005; 2. This study reports that permeability of the lung barrier to UFPs is controlled both at the epithelial and endothelial level, and is influenced by the inflammation.
-
(2005)
Part Fibre Toxicol
, pp. 2
-
-
Meiring, J.1
Borm, P.J.A.2
Bagate, K.3
-
63
-
-
12444328364
-
Evaluation of particle translocation across the alveolo-capillary barrier in isolated perfused rabbit lung model
-
This study demonstrates that UFPs diffuse from the vascular compartment into the lungs in an isolated perfused rabbit lung model, when the microvascular permeability is increased by histamine
-
Nemmar A, Hamoir J, Nemery B, Gustin P. Evaluation of particle translocation across the alveolo-capillary barrier in isolated perfused rabbit lung model. Toxicology 2005; 208:105-113. This study demonstrates that UFPs diffuse from the vascular compartment into the lungs in an isolated perfused rabbit lung model, when the microvascular permeability is increased by histamine.
-
(2005)
Toxicology
, vol.208
, pp. 105-113
-
-
Nemmar, A.1
Hamoir, J.2
Nemery, B.3
Gustin, P.4
-
64
-
-
32444451791
-
-
Mills NL, Amin N, Robinson SD, et al. Do inhaled carbon nanoparticles translocate directly into the circulation in man? Am J Respir Crit Care Med 2006; 173:426-431. This article did not confirm the earlier findings by Nemmar et al. [66].
-
Mills NL, Amin N, Robinson SD, et al. Do inhaled carbon nanoparticles translocate directly into the circulation in man? Am J Respir Crit Care Med 2006; 173:426-431. This article did not confirm the earlier findings by Nemmar et al. [66].
-
-
-
-
65
-
-
0037192333
-
Passage of inhaled particles into the blood circulation in humans
-
Nemmar A, Hoet PH, Vanquickenborne B, et al. Passage of inhaled particles into the blood circulation in humans. Circulation 2002; 105: 411-414.
-
(2002)
Circulation
, vol.105
, pp. 411-414
-
-
Nemmar, A.1
Hoet, P.H.2
Vanquickenborne, B.3
-
66
-
-
0036796601
-
Ultrafine particles affect experimental thrombosis in an in vivo hamster model
-
Nemmar A, Hoylaerts M, Hoet PHM, et al. Ultrafine particles affect experimental thrombosis in an in vivo hamster model. Am J Respir Crit Care Med 2002; 166:998-1004.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 998-1004
-
-
Nemmar, A.1
Hoylaerts, M.2
Hoet, P.H.M.3
-
67
-
-
0037289178
-
Size effect of intratracheally instilled particles on pulmonary inflammation and vascular thrombosis
-
Nemmar A, Hoylaerts MF, Hoet PHM, et al. Size effect of intratracheally instilled particles on pulmonary inflammation and vascular thrombosis. Toxicol Appl Pharmacol 2003; 186:38-45.
-
(2003)
Toxicol Appl Pharmacol
, vol.186
, pp. 38-45
-
-
Nemmar, A.1
Hoylaerts, M.F.2
Hoet, P.H.M.3
-
68
-
-
20544461398
-
The rat ear vein model for investigating in vivo thrombogenicity of ultrafine particles (Ufp)
-
This is an excellent study that validated the use of a noninvasive ear vein model in rats to evaluate the thrombogenic effects of UFP deposition in the respiratory tract
-
Silva VM, Corson N, Elder A, Oberdorster G. The rat ear vein model for investigating in vivo thrombogenicity of ultrafine particles (Ufp). Toxicol Sci 2005; 85:983-989. This is an excellent study that validated the use of a noninvasive ear vein model in rats to evaluate the thrombogenic effects of UFP deposition in the respiratory tract.
-
(2005)
Toxicol Sci
, vol.85
, pp. 983-989
-
-
Silva, V.M.1
Corson, N.2
Elder, A.3
Oberdorster, G.4
-
69
-
-
0037418167
-
Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis
-
Nemmar A, Hoet PH, Dinsdale D, et al. Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis. Circulation 2003; 107:1202-1208.
-
(2003)
Circulation
, vol.107
, pp. 1202-1208
-
-
Nemmar, A.1
Hoet, P.H.2
Dinsdale, D.3
-
70
-
-
0344825047
-
Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters - role of histamine
-
Nemmar A, Nemery B, Hoet PHM, et al. Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters - role of histamine. Am J Respir Crit Care Med 2003; 168:1366-1372.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 1366-1372
-
-
Nemmar, A.1
Nemery, B.2
Hoet, P.H.M.3
-
71
-
-
4644288256
-
Pharmacological stabilization of mast cells abrogates late thrombotic events induced by diesel exhaust particles in hamsters
-
Nemmar A, Hoet PHM, Vermylen J, et al. Pharmacological stabilization of mast cells abrogates late thrombotic events induced by diesel exhaust particles in hamsters. Circulation 2004; 110:1670-1677.
-
(2004)
Circulation
, vol.110
, pp. 1670-1677
-
-
Nemmar, A.1
Hoet, P.H.M.2
Vermylen, J.3
-
72
-
-
17644382715
-
Silica particles enhance peripheral thrombosis: Key role of lung macrophage-neutrophil cross-talk
-
This is a mechanistic study showing the importance of pulmonary macrophage-neutrophil cross-talk, in releasing neutrophil elastase into the blood, and causing platelet activation and thrombotic events on mildly damaged vasculature
-
Nemmar A, Nemery B, Hoet PH, et al. Silica particles enhance peripheral thrombosis: key role of lung macrophage-neutrophil cross-talk. Am J Respir Crit Care Med 2005; 171:872-879. This is a mechanistic study showing the importance of pulmonary macrophage-neutrophil cross-talk, in releasing neutrophil elastase into the blood, and causing platelet activation and thrombotic events on mildly damaged vasculature.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 872-879
-
-
Nemmar, A.1
Nemery, B.2
Hoet, P.H.3
-
73
-
-
0037139275
-
Particulate air pollution induces progression of atherosclerosis
-
Suwa T, Hogg JC, Quinlan KB, et al. Particulate air pollution induces progression of atherosclerosis. J Am Coll Cardiol 2002; 39:935-942.
-
(2002)
J Am Coll Cardiol
, vol.39
, pp. 935-942
-
-
Suwa, T.1
Hogg, J.C.2
Quinlan, K.B.3
-
74
-
-
85136388606
-
-
-/- mouse model, that long-term exposure to low concentration of PM2.5 altered vasomotor tone, induced vascular inflammation, and potentiated atherosclerosis.
-
-/- mouse model, that long-term exposure to low concentration of PM2.5 altered vasomotor tone, induced vascular inflammation, and potentiated atherosclerosis.
-
-
-
-
75
-
-
27744477066
-
-
Geys J, Coenegrachts L, Vercammen V, et al. In vitro study of the pulmonary translocation of nanoparticles: a preliminary study. Toxicol Lett 2006; 160:218-226. An interesting preliminary study on in-vitro translocation of UFPs, reporting that the Calu-3 cell line can be used in an in-vitro translocation study.
-
Geys J, Coenegrachts L, Vercammen V, et al. In vitro study of the pulmonary translocation of nanoparticles: a preliminary study. Toxicol Lett 2006; 160:218-226. An interesting preliminary study on in-vitro translocation of UFPs, reporting that the Calu-3 cell line can be used in an in-vitro translocation study.
-
-
-
-
76
-
-
33846310337
-
E-selectin expression in human endothelial cells exposed to PM10: The role of endotoxin and insoluble fraction
-
in press
-
Alfaro-Moreno E, López-Marure R, Montiel-Dávalos A, et al. E-selectin expression in human endothelial cells exposed to PM10: the role of endotoxin and insoluble fraction. Environ Res (in press).
-
Environ Res
-
-
Alfaro-Moreno, E.1
López-Marure, R.2
Montiel-Dávalos, A.3
-
77
-
-
34548823013
-
10 induce the expression of adhesion molecules and the adhesion of monocytic cells to human umbilical vein endothelial cells
-
in press
-
10 induce the expression of adhesion molecules and the adhesion of monocytic cells to human umbilical vein endothelial cells. Inhalation Toxicol (in press).
-
Inhalation Toxicol
-
-
Montiel-Dávalos, A.1
Alfaro-Moreno, E.2
López-Marure, R.3
-
78
-
-
33746606000
-
-
2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells. Am J Physiol Cell Physiol 2006; 291:C357-C365. An excellent mechanistic study of the effects of urban particles on pulmonary artery endothelial cells.
-
2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells. Am J Physiol Cell Physiol 2006; 291:C357-C365. An excellent mechanistic study of the effects of urban particles on pulmonary artery endothelial cells.
-
-
-
|