Potential in vitro effects of carbon nanotubes on human aortic endothelial cells

Toxicology and Applied Pharmacology

Volumn 236, Issue 3, 2009, Pages 319-328

  Walker, Valerie G ^a   Li, Zheng ^a   Hulderman, Tracy ^a   Schwegler Berry, Diane ^a   Kashon, Michael L ^a   Simeonova, Petia P ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Actin; Cytotoxicity; MWCNT; SWCNT; Tubule formation

Indexed keywords

ACTIN; CARBON NANOTUBE; INTERLEUKIN 8; LACTATE DEHYDROGENASE; MULTI WALLED NANOTUBE; SINGLE WALLED NANOTUBE; VASCULAR ENDOTHELIAL CADHERIN;

ACTIN FILAMENT; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CELL FUNCTION; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; ENZYME RELEASE; EXPOSURE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG TOXICITY; MEMBRANE PERMEABILITY;

ANTIGENS, CD; AORTA; CADHERINS; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERLEUKIN-8; L-LACTATE DEHYDROGENASE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NANOTUBES, CARBON;

MUS;

EID: 63649110317     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.02.018     Document Type: Article

References (50)

1. Bootle-Wilbraham C.A., Tazzyman S., Marshall J.M., and Lewis C.E. Fibrinogen E-fragment inhibits the migration and tubule formation of human dermal microvascular endothelial cells in vitro. Cancer Res. 60 (2000) 4719-4724
2. Borm P.J., Robbins D., Haubold S., Kuhlbusch T., Fissan H., Donaldson K., Schins R., Stone V., Kreyling W., Lademann J., Krutmann J., Warheit D., and Oberdorster E. The potential risks of nanomaterials: a review carried out for ECETOC. Part Fibre Toxicol. 3 (2006) 11
3. Brook R.D., Franklin B., Cascio W., Hong Y., Howard G., Lipsett M., Luepker R., Mittleman M., Samet J., Smith Jr. S.C., and Tager I. Air pollution and cardiovascular disease: a statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart Association. Circulation 109 (2004) 2655-2671
4. Cai H., and Harrison D.G. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res. 87 (2000) 840-844
5. Carlier M.F., Le Clainche C., Wiesner S., and Pantaloni D. Actin-based motility: from molecules to movement. Bioessays 25 (2003) 336-345
6. Casey A., Herzog E., Lyng F.M., Byrne H.J., Chambers G., and Davoren M. Single walled carbon nanotubes induce indirect cytotoxicity by medium depletion in A549 lung cells. Toxicol. Lett. 179 (2008) 78-84
7. Donaldson K., Aitken R., Tran L., Stone V., Duffin R., Forrest G., and Alexander A. Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol. Sci. 92 (2006) 5-22
8. Erdely A., Hulderman T., Salmen R., Liston A., Zeidler-Erdely P.C., Schwegler-Berry D., Castranova V., Koyama S., Kim Y.A., Endo M., and Simeonova P.P. Cross-talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential Biomarkers Nano Lett. 9 (2009) 36-43
9. Gatesman A., Walker V.G., Baisden J.M., Weed S.A., and Flynn D.C. Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110. Mol. Cell. Biol. 24 (2004) 7578-7597
10. Goode B.L., Drubin D.G., and Barnes G. Functional cooperation between the microtubule and actin cytoskeletons. Curr. Opin. Cell Biol. 12 (2000) 63-71
11. Hartsock A., and Nelson W.J. Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim. Biophys. Acta 1778 (2008) 660-669
12. Heckel K., Kiefmann R., Dorger M., Stoeckelhuber M., and Goetz A.E. Colloidal gold particles as a new in vivo marker of early acute lung injury. Am. J. Physiol., Lung Cell. Mol. Physiol. 287 (2004) L867-L878
13. Hirano S., Kanno S., and Furuyama A. Multi-walled carbon nanotubes injure the plasma membrane of macrophages. Toxicol. Appl. Pharmacol. 232 (2008) 244-251
14. Horowitz A., and Simons M. Branching morphogenesis. Circ. Res. 103 (2008) 784-795
15. Kim Y.A., Hayashi T., Endo M., Kaburagi Y., Tsukada T., Shan J., Osato K., and Tsuruoka S. Synthesis and structural characterization of thin multi-walled carbon nanotubes with a partially facetted cross section by a floating reactant method. Carbon 43 (2005) 2243-2250
16. Kovacs E.M., Goodwin M., Ali R.G., Paterson A.D., and Yap A.S. Cadherin-directed actin assembly: E-cadherin physically associates with the Arp2/3 complex to direct actin assembly in nascent adhesive contacts. Curr. Biol. 12 (2002) 379-382
17. Koyama S., Endo M., Kim Y.-A., Hayashi T., Yanagisawa T., Osaka K., Koyama H., Haniu H., and Kuroiwa N. Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice. Carbon 44 (2006) 1079-1092
18. Kreyling W.G., Semmler M., Erbe F., Mayer P., Takenaka S., Schulz H., Oberdorster G., and Ziesenis A. Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmonary organs is size dependent but very low. J. Toxicol. Environ. Health 65 (2002) 1513-1530
19. Lam C.W., James J.T., McCluskey R., and Hunter R.L. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol. Sci. 77 (2004) 126-134
20. Li J.G., Li W.X., Xu J.Y., Cai X.Q., Liu R.L., Li Y.J., Zhao Q.F., and Li Q.N. Comparative study of pathological lesions induced by multiwalled carbon nanotubes in lungs of mice by intratracheal instillation and inhalation. Environ. Toxicol. 22 (2007) 415-421
21. Li Z., Hulderman T., Salmen R., Chapman R., Leonard S.S., Young S.H., Shvedova A., Luster M.I., and Simeonova P.P. Cardiovascular effects of pulmonary exposure to single-wall carbon nanotubes. Environ. Health Perspect. 115 (2007) 377-382
22. Mangum J.B., Turpin E.A., Antao-Menezes A., Cesta M.F., Bermudez E., and Bonner J.C. Single-walled carbon nanotube (SWCNT)-induced interstitial fibrosis in the lungs of rats is associated with increased levels of PDGF mRNA and the formation of unique intercellular carbon structures that bridge alveolar macrophages in situ. Part Fibre Toxicol. 3 (2006) 15
23. Manna S.K., Sarkar S., Barr J., Wise K., Barrera E.V., Jejelowo O., Rice-Ficht A.C., and Ramesh G.T. Single-walled carbon nanotube induces oxidative stress and activates nuclear transcription factor-kappaB in human keratinocytes. Nano Lett. 5 (2005) 1676-1684
24. Maynard A.D., Aitken R.J., Butz T., Colvin V., Donaldson K., Oberdorster G., Philbert M.A., Ryan J., Seaton A., Stone V., Tinkle S.S., Tran L., Walker N.J., and Warheit D.B. Safe handling of nanotechnology. Nature 444 (2006) 267-269
25. Mercer R.R., Scabilloni J., Wang L., Kisin E., Murray A.R., Schwegler-Berry D., Shvedova A.A., and Castranova V. Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model. Am. J. Physiol., Lung. Cell Mol. Physiol. 294 (2008) L87-L97
26. Mills N.L., Tornqvist H., Robinson S.D., Gonzalez M.C., Soderberg S., Sandstrom T., Blomberg A., Newby D.E., and Donaldson K. Air pollution and atherothrombosis. Inhal. Toxicol. 19 Suppl. 1 (2007) 81-89
27. Mills N.L., Miller J.J., Anand A., Robinson S.D., Frazer G.A., Anderson D., Breen L., Wilkinson I.B., McEniery C.M., Donaldson K., Newby D.E., and Macnee W. Increased arterial stiffness in patients with chronic obstructive pulmonary disease: a mechanism for increased cardiovascular risk. Thorax 63 (2008) 306-311
28. Mills N.L., Oberdorster G., and Newby D.E. Reducing exposure to airborne particles: a novel strategy to improve cardiovascular health. Am. J. Respir. Crit. Care Med. 177 (2008) 366-367
29. Miyoshi J., and Takai Y. Structural and functional associations of apical junctions with cytoskeleton. Biochim. Biophys. Acta 1778 (2008) 670-691
30. Monteiro-Riviere N.A., Nemanich R.J., Inman A.O., Wang Y.Y., and Riviere J.E. Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicol. Lett. 155 (2005) 377-384
31. Moreau V., Tatin F., Varon C., and Genot E. Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA. Mol. Cell. Biol. 23 (2003) 6809-6822
32. Muller J., Huaux F., Moreau N., Misson P., Heilier J.F., Delos M., Arras M., Fonseca A., Nagy J.B., and Lison D. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol. Appl. Pharmacol. 207 (2005) 221-231
33. Nemmar A., Hoet P.H., Vanquickenborne B., Dinsdale D., Thomeer M., Hoylaerts M.F., Vanbilloen H., Mortelmans L., and Nemery B. Passage of inhaled particles into the blood circulation in humans. Circulation 105 (2002) 411-414
34. Oberdorster G., Sharp Z., Atudorei V., Elder A., Gelein R., Lunts A., Kreyling W., and Cox C. Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J. Toxicol. Environ. Health 65 (2002) 1531-1543
35. Oberlin A., Endo M., and Koyama T. Filamentous growth of carbon through benzene decomposition. J. Cryst. Growth 32 (1976) 335-349
36. Pacurari M., Yin X.J., Ding M., Leonard S.S., Schwegler-berry D., Ducatman B.S., Chirila M., Endo M., Castranova V., and Vallyathan V. Oxidative and molecular interactions of multi-wall carbon nanotubes (MWCNT) in normal and malignant human mesothelial cells. Nanotoxicology 2 (2008) 155-170
37. Pacurari M., Yin X.J., Zhao J., Ding M., Leonard S.S., Schwegler-Berry D., Ducatman B.S., Sbarra D., Hoover M.D., Castranova V., and Vallyathan V. Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells. Environ. Health Perspect. 116 (2008) 1211-1217
38. Petrache I., Birukova A., Ramirez S.I., Garcia J.G., and Verin A.D. The role of the microtubules in tumor necrosis factor-alpha-induced endothelial cell permeability. Am. J. Respir. Cell Mol. Biol. 28 (2003) 574-581
39. Porter A.E., Gass M., Muller K., Skepper J.N., Midgley P.A., and Welland M. Direct imaging of single-walled carbon nanotubes in cells. Nat. Nanotechnology 2 (2007) 713-717
40. Qian Y., Baisden J.M., Westin E.H., Guappone A.C., Koay T.C., and Flynn D.C. Src can regulate carboxy terminal interactions with AFAP-110, which influence self-association, cell localization and actin filament integrity. Oncogene 16 (1998) 2185-2195
41. Raja P.M., Connolley J., Ganesan G.P., Ci L., Ajayan P.M., Nalamasu O., and Thompson D.M. Impact of carbon nanotube exposure, dosage and aggregation on smooth muscle cells. Toxicol. Lett. 169 (2007) 51-63
42. Shvedova A.A., Castranova V., Kisin E.R., Schwegler-Berry D., Murray A.R., Gandelsman V.Z., Maynard A., and Baron P. Exposure to carbon nanotube material: assessment of nanotube cytotoxicity using human keratinocyte cells. J. Toxicol. Environ. Health 66 (2003) 1909-1926
43. Shvedova A.A., Kisin E.R., Mercer R., Murray A.R., Johnson V.J., Potapovich A.I., Tyurina Y.Y., Gorelik O., Arepalli S., Schwegler-Berry D., Hubbs A.F., Antonini J., Evans D.E., Ku B.K., Ramsey D., Maynard A., Kagan V.E., Castranova V., and Baron P. Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am. J. Physiol., Lung Cell. Mol. Physiol. 289 (2005) L698-L708
44. Simeonova P.P., and Luster M.I. Asbestos induction of nuclear transcription factors and interleukin 8 gene regulation. Am. J. Respir. Cell Mol. Biol. 15 (1996) 787-795
45. Vailhe B., Lecomte M., Wiernsperger N., and Tranqui L. The formation of tubular structures by endothelial cells is under the control of fibrinolysis and mechanical factors. Angiogenesis 2 (1998) 331-344
46. Vandenbroucke E., Mehta D., Minshall R., and Malik A.B. Regulation of endothelial junctional permeability. Ann. N.Y. Acad. Sci. 1123 (2008) 134-145
47. Vouret-Craviari V., Boquet P., Pouyssegur J., and Van Obberghen-Schilling E. Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function. Mol. Biol. Cell 9 (1998) 2639-2653
48. Warheit D.B., Laurence B.R., Reed K.L., Roach D.H., Reynolds G.A., and Webb T.R. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicol. Sci. 77 (2004) 117-125
49. Worle-Knirsch J.M., Pulskamp K., and Krug H.F. Oops they did it again! Carbon nanotubes hoax scientists in viability assays. Nano Lett. 6 (2006) 1261-1268
50. Yamawaki H., and Iwai N. Mechanisms underlying nano-sized air-pollution-mediated progression of atherosclerosis: carbon black causes cytotoxic injury/inflammation and inhibits cell growth in vascular endothelial cells. Circ. J. 70 (2006) 129-140