Acute exposure to diesel exhaust increases IL-8 and GRO-α production in healthy human airways

American Journal of Respiratory and Critical Care Medicine

Volumn 161, Issue 2 I, 2000, Pages 550-557

  Salvi, Sundeep S ^a   Nordenhall, Charlotta ^b   Blomberg, Anders ^b   Rudell, Bertil ^b   Pourazar, Jamshid ^b   Kelly, Frank J ^b   Wilson, Susan ^b   Sandström, Thomas ^b   Holgate, Stephen T ^b   Frew, Anthony J ^b  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH REGULATED ONCOGENE ALPHA PROTEIN; INTERLEUKIN 5; INTERLEUKIN 8; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; AIR POLLUTION; ARTICLE; BRONCHUS MUCOSA; CELL INFILTRATION; EXHAUST GAS; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOPATHOLOGY; INFLAMMATION; MALE; MEDIATOR RELEASE; NORMAL HUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM;

EID: 0034016108     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.161.2.9905052     Document Type: Article

References (38)

1. Dockery, D. W., and C. A. Pope. 1994. Acute respiratory effects of particulate air pollution. Annu. Rev. Public Health 15:107-132.
2. Salvi, S., A. Blomberg, B. Rudell, F. J. Kelly, T. Sandstrom, S. T. Holgate, and A. J. Frew. 1999. Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. Am. J. Respir. Crit. Care Med. 159:702-709.
3. Baggiolini, M. 1998. Chemokines and leukocyte traffic. Nature 329:565-568.
4. Bouthillier, L., R. Vincent, P. Goegan, I. Y. Adamson, S. Bjarnason, M. Stewart, J. Guenette, M. Potvin, and P. Kumarathasan. 1998. Acute effects of inhaled urban particles and ozone: lung morphology, macrophage activity and plasma endothelin-1. Am. J. Pathol. 153:1873-1884.
5. Bayram, H., J. L. Devalia, R. J. Sapsford, T. Ohtoshi, Y. Miyabra, M. Sagai, and R. J. Davies. 1998. The effect of diesel exhaust particles on cell function and release of inflammatory mediators from human bronchial epithelial cells in vitro. Am. J. Respir. Cell Mol. Biol. 18: 441-448.
6. Steerenberg, P. A., J. A. J. Zonnenberg, J. Dormans, P. N. T. Joon, I. M. Wouters, L. van Bree, P. T. J. Scheepers, and H. van Loveren. 1998. Diesel exhaust particles induced release of IL-6 and IL-8 by (primed) human bronchial epithelial cells (BEAS-2B) in-vitro. Exp. Lung Res. 24:85-100.
7. Ohtoshi, T., H. Takizawa, H. Okazaki, S. Kawasaki, N. Takeuchi, K. Ohta, and K. Ito. 1998. Diesel exhaust particles stimulate human airway epithelial cells to produce cytokines relevant to airway inflammation in vitro. J. Allergy Clin. Immunol. 101(6, Pt. 1):778-785.
8. Shi, M. M., J. J. Godleski, and J. D. Paulauskis. 1996. Regulation of MIP-I mRNA by oxidative stress. J. Biol. Chem. 271:5878-5883.
9. Takano, H., T. Yoshikawa, T. Ichinose, Y. Miyabara, K. Imaoka, and M. Sagai. 1997. Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in mice. Am. J. Respir. Crit Care Me. 56:36-42.
10. Miyabara, Y., T. Ichinose, H. Takano, H. B. Lim, and M. Sagai. 1998. Effects of diesel exhaust on allergic airway inflammation in mice. J. Allergy Clin. Immunol. 102:805-812.
11. Ichinose, T., H. Takano, Y. Miyabara, and M. Sagai. 1998. Long term exposure to diesel exhaust enhances antigen induced cosinophilic inflammation and epithelial damage in the murine airway. Toxicol. Sci. 44:70-79.
12. Yang, H. M., Y. J. Ma, V. Castranova, and J. K. Ma. 1997. Effects of diesel exhaust particles on the release of interleukin-1 and tumor necrosis factor-alpha from rat alveolar macrophages. Exp. Lung Res. 23:269-284.
13. Nel, A. E., D. Diaz-Sanchez, D. Ng, T. Hiura, and A. Saxon. 1998. Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system. J. Allergy Clin. Immunol. 102 (4, Pt. I):539-554.
14. Takano, H., T. Ichinose, Y. Miyahara, T. Shibuya, H. B. Lim, T. Yoshikawa, and M. Sagai. 1998. Inhalation of DE enhances allergen related eosinophil recruitment and airway hyperresponsiveness in mice. Toxicol. Appl. Pharmacol. 150:238-337.
15. Rudell, B., T. Sandstrom, U. Hammarstrom, M. C. Ledin, P. Horstedt, and N. Stjernberg. 1994. Evaluation of an exposure setup for studying effects of diesel in humans. Int. Arch. Occup. Environ. Health 66:77-83.
16. Britten, K. M., P. H. Howarth, and W. R. Roche. 1993. Immunohistochemistry on resin sections: a comparison of resin embedding techniques for small mucosal biopsies. Biotech. Histochem. 68:271-280.
17. Wilson, S. J., B. A. Leone, D. Anderson, A. Manning, and S. T. Holgate. 1999. Immunohistochemical analysis of the activation of NF-κB and expression of associated cytokines and adhesion molecules in human models of allergic inflammation. J. Pathol. (In press)
18. Salvi, S. S., A. Semper, A. Blomberg, J. Holloway, R. Polosa, A. Papi, L. Teran, F. J. Kelly, T. Sandstrom, S. T. Holgate, and A. J. Frew. 1999. Interleukin-5 production by human airway epithelial cells. Am. J. Respir. Cell Mol. Biol. 20:984-991.
19. Baggiolini, M., and I. Clark-Lewis. 1992. IL-8, a chemotactic and inflammatory cytokine. F.E.B.S. Lett. 307:97-101.
20. Baggiolini, M., B. Dewald, and B. Moser. 1994. IL-8 and related chemotactic cytokines - C-X-C and CC chemokines. Adv. Immunol. 55:97-179.
21. Braun, R. K., M. Franchini, F. Erard, S. Rihs, I. J. M. Derries, K. Blaser, T. T. Hansel, and C. Walker. 1993. Human peripheral blood cosino-phils produce and release IL-8 on stimulation with calcium ionophore. Eur. J. Immunol. 23:956-960.
22. Larsen, C. G., A. O. Anderson, E. Appella, J. J. Oppenheim, and K. Matsushima. 1989. Neutrophil activating protein (NAP-1) is also chemotactic for T lymphocytes. Science 243:1463-1466.
23. Shute, J. K., I. Lindley, P. Peichi, S. T. Holgate, M. K. Church, and R. Djukanovic. 1995. Mucosal IgA is an important moderator of eosino-phil migratory responses to tissue derived chemoattractants. Int. Arch. Allergy Immunol. 107:428-429.
24. Kernen, P., M. P. Wymann, V. von Tscharner, D. A. Deranleau, P. C. Tai, C. J. Spry, C. A. Dahinden, and M. Baggiolini. 1991. Shape change, exocytosis and cytosolic free calcium changes in stimulated free eosinophils. J. Clin. Invest. 87:2012-2017.
25. White, M. V., T. Yoshimura, W. Hook, M. Kaliner, and E. J. Leonard. 1989. Neutrophil activating protein (NAP-1) causes human basophil histamine release. Immunol. Lett. 22:151-154.
26. Dahinden, C. A., Y. Kurimoto, A. L. De Weck, I. Lindley, B. Dewald, and M. Baggiolini. 1989. The neutrophil activating peptide NAF/ NAP-1 induces histamine and leukotriene release by IL-3 primed basophils. J. Exp. Med. 170:1787-1792.
27. Bischoff, S. C., M. Krieger, T. Brunner, A. Rot, V. van Tscharner, M. Baggiolini, and C. A. Dahinden. 1993. RANTES and related chemokines activate human basophil granulocytes through different G-coupled protein receptors. Eur. J. Immunol. 23:761-767.
28. Srivastava, M. D., R. Srivastava, and B. S. Srivastava. 1993. Constitutive production of IL-8 by normal and malignant human B-cells and other cell types. Leukemia Res. 17:1063-1069.
29. Yousefi, S., S. Haemman, M. Weber, C. Holzer, K. Hartung, K. Blaser, and H. U. Simon. 1995. IL-8 is expressed by human peripheral blood cosinophils: evidence for increased secretion in asthma. J. Immunol. 154: 5481-5490.
30. Devalia, J. L., A. M. Campbell, R. J. Sapsford, D. Rusznak, D. Quint, and P. Godard. 1993. Effect of nitrogen dioxide on synthesis of inflammalory cytokines expressed by human bronchial epithelial cells in vitro. Am. J. Respir. Cell Mol. Biol. 9:271-278.
31. Bazzoni, F., M. A. Cassatella, M. Rossi, M. Ceska, B. Dewald, and M. Baggiolini. 1991. Phagocytosing neutrophils produce and release high amounts of the neulrophil activating peptide-1/IL-8. J. Exp. Med. 173: 771-774.
32. Redington, A. E., P. Bradding, J. A. Douglas, P. H. Howarth, and S. T. Holgate. 1993. Bronchial epithelial cytokine production in asthmatics and non-asthmatics (abstract). Thorax 48:1081.
33. Terada, N., N. Hamano, K.I. Maesako, K. Hiruma, G. Hohki, K. Suzuki, K. Ishikawa, and A. Konno. 1999. Diesel exhaust particulates upregulate histamine receptor mRNA and increase histamine-induced IL-8 and GM-CSF production in nasal epithelial cells and endothelial cells. Clin. Exp. Allergy 29:52-59.
34. Mukaida, N., Y. Mahe, and K. Matsushima. 1990. Cooperative interaction of NF-κB and cis-regulatory enhancer binding protein-like factor binding elements in activating the IL-8 gene by proinflammatory cytokines. J. Biol Chem. 265:21128-21133.
35. Granger, D. N. 1988. Role of xanthine-oxidase and granulocytes in ischemia-reperfusion injury. Am. J. Physiol. 255:H1269-H1275.
36. Webb, L. M. C., M. U. Ehrengruber, I. Clark-Lewis, M. Baggiolini, and A. Rot. 1993. Binding to heparan sulfate or heparin enhances neutrophil responses to IL-8. Proc. Natl. Acad. Sci. U.S.A. 90:7158-7162.
37. Erger, R. A., and T. B. Casale. 1998. IL-8 plays a significant role in IgE mediated lung inflammation. Eur. Respir. J. 11:299-305.
38. United Nations Environment Programme. 1994. Air Pollution in the world's megacities. Environment 36:5-37.