-
1
-
-
84869041395
-
Development and characterization of a new Parkinson's disease model resulting from impaired autophagy.
-
Ahmed, I., Liang, Y., Schools, S., Dawson, V. L., Dawson, T. M., and Savitt, J. M. (2012). Development and characterization of a new Parkinson's disease model resulting from impaired autophagy. J. Neurosci. 32, 16503-16509.
-
(2012)
J. Neurosci.
, vol.32
, pp. 16503-16509
-
-
Ahmed, I.1
Liang, Y.2
Schools, S.3
Dawson, V.L.4
Dawson, T.M.5
Savitt, J.M.6
-
2
-
-
0030805622
-
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease.
-
Alam, Z. I., Daniel, S. E., Lees, A. J., Marsden, D. C., Jenner, P., and Halliwell, B. (1997a). A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J. Neurochem. 69, 1326-1329.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1326-1329
-
-
Alam, Z.I.1
Daniel, S.E.2
Lees, A.J.3
Marsden, D.C.4
Jenner, P.5
Halliwell, B.6
-
3
-
-
0030878073
-
Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.
-
Alam, Z. I., Jenner, A., Daniel, S. E., Lees, A. J., Cairns, N., Marsden, C. D., et al. (1997b). Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J. Neurochem. 69, 1196-1203.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1196-1203
-
-
Alam, Z.I.1
Jenner, A.2
Daniel, S.E.3
Lees, A.J.4
Cairns, N.5
Marsden, C.D.6
-
4
-
-
0033772264
-
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28.
-
Alexander, C., Votruba, M., Pesch, U. E., Thiselton, D. L., Mayer, S., Moore, A., et al. (2000). OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28. Nat. Genet. 26, 211-215.
-
(2000)
Nat. Genet.
, vol.26
, pp. 211-215
-
-
Alexander, C.1
Votruba, M.2
Pesch, U.E.3
Thiselton, D.L.4
Mayer, S.5
Moore, A.6
-
5
-
-
35548972027
-
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase.
-
Andres-Mateos, E., Perier, C., Zhang, L., Blanchard-Fillion, B., Greco, T. M., Thomas, B., et al. (2007). DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc. Natl. Acad. Sci. U.S.A. 104, 14807-14812.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 14807-14812
-
-
Andres-Mateos, E.1
Perier, C.2
Zhang, L.3
Blanchard-Fillion, B.4
Greco, T.M.5
Thomas, B.6
-
6
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease.
-
Auluck, P. K., Chan, H. Y., Trojanowski, J. Q., Lee, V. M., and Bonini, N. M. (2002). Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295, 865-868.
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
7
-
-
84863308390
-
Pink1 kinase and its membrane potential (Deltapsi)-dependent cleavage product both localize to outer mitochondrial membrane by unique targeting mode.
-
Becker, D., Richter, J., Tocilescu, M. A., Przedborski, S., and Voos, W. (2012). Pink1 kinase and its membrane potential (Deltapsi)-dependent cleavage product both localize to outer mitochondrial membrane by unique targeting mode. J. Biol. Chem. 287, 22969-22987.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 22969-22987
-
-
Becker, D.1
Richter, J.2
Tocilescu, M.A.3
Przedborski, S.4
Voos, W.5
-
8
-
-
51149121890
-
Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.
-
Bedford, L., Hay, D., Devoy, A., Paine, S., Powe, D. G., Seth, R., et al. (2008). Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies. J. Neurosci. 28, 8189-8198.
-
(2008)
J. Neurosci.
, vol.28
, pp. 8189-8198
-
-
Bedford, L.1
Hay, D.2
Devoy, A.3
Paine, S.4
Powe, D.G.5
Seth, R.6
-
9
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease.
-
Betarbet, R., Sherer, T. B., Mackenzie, G., Garcia-Osuna, M., Panov, A. V., and Greenamyre, J. T. (2000). Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3, 1301-1306.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
Mackenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
10
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease.
-
Braak, H., Del Tredici, K., Rub, U., De Vos, R. A., Jansen Steur, E. N., and Braak, E. (2003). Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging 24, 197-211.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
De Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
11
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.
-
Canet-Aviles, R. M., Wilson, M. A., Miller, D. W., Ahmad, R., McLendon, C., Bandyopadhyay, S., et al. (2004). The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl. Acad. Sci. U.S.A. 101, 9103-9108.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
-
12
-
-
34347359673
-
Rejuvenation protects neurons in mouse models of Parkinson's disease.
-
Chan, C. S., Guzman, J. N., Ilijic, E., Mercer, J. N., Rick, C., Tkatch, T., et al. (2007). "Rejuvenation" protects neurons in mouse models of Parkinson's disease. Nature 447, 1081-1086.
-
(2007)
Nature
, vol.447
, pp. 1081-1086
-
-
Chan, C.S.1
Guzman, J.N.2
Ilijic, E.3
Mercer, J.N.4
Rick, C.5
Tkatch, T.6
-
13
-
-
79954520907
-
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy.
-
Chan, N. C., Salazar, A. M., Pham, A. H., Sweredoski, M. J., Kolawa, N. J., Graham, R. L., et al. (2011). Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum. Mol. Genet. 20, 1726-1737.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1726-1737
-
-
Chan, N.C.1
Salazar, A.M.2
Pham, A.H.3
Sweredoski, M.J.4
Kolawa, N.J.5
Graham, R.L.6
-
14
-
-
84872691988
-
Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons.
-
Cherra, S. J. III, Steer, E., Gusdon, A. M., Kiselyov, K., and Chu, C. T. (2013). Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons. Am. J. Pathol. 182, 474-484.
-
(2013)
Am. J. Pathol.
, vol.182
, pp. 474-484
-
-
Cherra, S.J.1
Steer, E.2
Gusdon, A.M.3
Kiselyov, K.4
Chu, C.T.5
-
15
-
-
84863584524
-
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.
-
Cooper, O., Seo, H., Andrabi, S., Guardia-Laguarta, C., Graziotto, J., Sundberg, M., et al. (2012). Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease. Sci. Transl. Med. 4, 141ra190.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Cooper, O.1
Seo, H.2
Andrabi, S.3
Guardia-Laguarta, C.4
Graziotto, J.5
Sundberg, M.6
-
16
-
-
4344659685
-
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.
-
Cuervo, A. M., Stefanis, L., Fredenburg, R., Lansbury, P. T., and Sulzer, D. (2004). Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 305, 1292-1295.
-
(2004)
Science
, vol.305
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stefanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
17
-
-
0141741347
-
Parkinson's disease: mechanisms and models.
-
Dauer, W., and Przedborski, S. (2003). Parkinson's disease: mechanisms and models. Neuron 39, 889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
18
-
-
77953424577
-
The role of parkin in familial and sporadic Parkinson's disease.
-
Dawson, T. M., and Dawson, V. L. (2010). The role of parkin in familial and sporadic Parkinson's disease. Mov. Disord. 25(Suppl. 1), S32-S39.
-
(2010)
Mov. Disord.
, vol.25
, Issue.SUPPL. 1
-
-
Dawson, T.M.1
Dawson, V.L.2
-
19
-
-
20244381365
-
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy.
-
Delettre, C., Lenaers, G., Griffoin, J. M., Gigarel, N., Lorenzo, C., Belenguer, P., et al. (2000). Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy. Nat. Genet. 26, 207-210.
-
(2000)
Nat. Genet.
, vol.26
, pp. 207-210
-
-
Delettre, C.1
Lenaers, G.2
Griffoin, J.M.3
Gigarel, N.4
Lorenzo, C.5
Belenguer, P.6
-
20
-
-
77956252454
-
Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming.
-
Ding, W. X., Ni, H. M., Li, M., Liao, Y., Chen, X., Stolz, D. B., et al. (2010). Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. J. Biol. Chem. 285, 27879-27890.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 27879-27890
-
-
Ding, W.X.1
Ni, H.M.2
Li, M.3
Liao, Y.4
Chen, X.5
Stolz, D.B.6
-
21
-
-
33846572874
-
Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030.
-
Dorsey, E. R., Constantinescu, R., Thompson, J. P., Biglan, K. M., Holloway, R. G., Kieburtz, K., et al. (2007). Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030. Neurology 68, 384-386.
-
(2007)
Neurology
, vol.68
, pp. 384-386
-
-
Dorsey, E.R.1
Constantinescu, R.2
Thompson, J.P.3
Biglan, K.M.4
Holloway, R.G.5
Kieburtz, K.6
-
22
-
-
84861595545
-
Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of alpha-synuclein and LRRK2 in the brain.
-
Friedman, L. G., Lachenmayer, M. L., Wang, J., He, L., Poulose, S. M., Komatsu, M., et al. (2012). Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of alpha-synuclein and LRRK2 in the brain. J. Neurosci. 32, 7585-7593.
-
(2012)
J. Neurosci.
, vol.32
, pp. 7585-7593
-
-
Friedman, L.G.1
Lachenmayer, M.L.2
Wang, J.3
He, L.4
Poulose, S.M.5
Komatsu, M.6
-
23
-
-
84866498143
-
DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy.
-
Gao, H., Yang, W., Qi, Z., Lu, L., Duan, C., Zhao, C., et al. (2012). DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy. J. Mol. Biol. 423, 232-248.
-
(2012)
J. Mol. Biol.
, vol.423
, pp. 232-248
-
-
Gao, H.1
Yang, W.2
Qi, Z.3
Lu, L.4
Duan, C.5
Zhao, C.6
-
24
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.
-
Geisler, S., Holmstrom, K. M., Skujat, D., Fiesel, F. C., Rothfuss, O. C., Kahle, P. J., et al. (2010). PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat. Cell Biol. 12, 119-131.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
-
25
-
-
0018095085
-
Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones.
-
Graham, D. G. (1978). Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol. Pharmacol. 14, 633-643.
-
(1978)
Mol. Pharmacol.
, vol.14
, pp. 633-643
-
-
Graham, D.G.1
-
26
-
-
84859428688
-
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
-
Greene, A. W., Grenier, K., Aguileta, M. A., Muise, S., Farazifard, R., Haque, M. E., et al. (2012). Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. EMBO Rep. 13, 378-385.
-
(2012)
EMBO Rep.
, vol.13
, pp. 378-385
-
-
Greene, A.W.1
Grenier, K.2
Aguileta, M.A.3
Muise, S.4
Farazifard, R.5
Haque, M.E.6
-
27
-
-
78649866553
-
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.
-
Guzman, J. N., Sanchez-Padilla, J., Wokosin, D., Kondapalli, J., Ilijic, E., Schumacker, P. T., et al. (2010). Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. Nature 468, 696-700.
-
(2010)
Nature
, vol.468
, pp. 696-700
-
-
Guzman, J.N.1
Sanchez-Padilla, J.2
Wokosin, D.3
Kondapalli, J.4
Ilijic, E.5
Schumacker, P.T.6
-
28
-
-
18144406539
-
Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Exp.
-
Hald, A., and Lotharius, J. (2005). Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Exp. Neurol. 193, 279-290.
-
(2005)
Neurol.
, vol.193
, pp. 279-290
-
-
Hald, A.1
Lotharius, J.2
-
29
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice.
-
Hara, T., Nakamura, K., Matsui, M., Yamamoto, A., Nakahara, Y., Suzuki-Migishima, R., et al. (2006). Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441, 885-889.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
-
30
-
-
84858667311
-
Neuroinflammation in Parkinson's disease.
-
Hirsch, E. C., Vyas, S., and Hunot, S. (2012). Neuroinflammation in Parkinson's disease. Parkinsonism Relat. Disord. 18(Suppl. 1), S210-S212.
-
(2012)
Parkinsonism Relat. Disord.
, vol.18
, Issue.SUPPL. 1
-
-
Hirsch, E.C.1
Vyas, S.2
Hunot, S.3
-
31
-
-
84876903554
-
Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 upon mitochondrial dysfunction in neurons.
-
PMID:23508964, Epub ahead of print
-
Huang, Q., Wang, H., Perry, S. W., and Figueiredo-Pereira, M. E. (2013). Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 upon mitochondrial dysfunction in neurons. J. Biol. Chem. PMID:23508964. [Epub ahead of print].
-
(2013)
J. Biol. Chem.
-
-
Huang, Q.1
Wang, H.2
Perry, S.W.3
Figueiredo-Pereira, M.E.4
-
32
-
-
77956522541
-
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.
-
Irrcher, I., Aleyasin, H., Seifert, E. L., Hewitt, S. J., Chhabra, S., Phillips, M., et al. (2010). Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum. Mol. Genet. 19, 3734-3746.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
-
33
-
-
27144441722
-
Oxidative modification of proteasome: identification of an oxidation-sensitive subunit in 26 S proteasome.
-
Ishii, T., Sakurai, T., Usami, H., and Uchida, K. (2005). Oxidative modification of proteasome: identification of an oxidation-sensitive subunit in 26 S proteasome. Biochemistry 44, 13893-13901.
-
(2005)
Biochemistry
, vol.44
, pp. 13893-13901
-
-
Ishii, T.1
Sakurai, T.2
Usami, H.3
Uchida, K.4
-
34
-
-
84857850213
-
Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.
-
Itakura, E., Kishi-Itakura, C., Koyama-Honda, I., and Mizushima, N. (2012). Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy. J. Cell Sci. 125, 1488-1499.
-
(2012)
J. Cell Sci.
, vol.125
, pp. 1488-1499
-
-
Itakura, E.1
Kishi-Itakura, C.2
Koyama-Honda, I.3
Mizushima, N.4
-
35
-
-
33646948530
-
Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.
-
Keeney, P. M., Xie, J., Capaldi, R. A., and Bennett, J. P. Jr. (2006). Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled. J. Neurosci. 26, 5256-5264.
-
(2006)
J. Neurosci.
, vol.26
, pp. 5256-5264
-
-
Keeney, P.M.1
Xie, J.2
Capaldi, R.A.3
Bennett, J.P.Jr.4
-
36
-
-
20144389422
-
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.
-
Kim, R. H., Smith, P. D., Aleyasin, H., Hayley, S., Mount, M. P., Pownall, S., et al. (2005). Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proc. Natl. Acad. Sci. U.S.A. 102, 5215-5220.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 5215-5220
-
-
Kim, R.H.1
Smith, P.D.2
Aleyasin, H.3
Hayley, S.4
Mount, M.P.5
Pownall, S.6
-
37
-
-
80655124407
-
A comprehensive glossary of autophagy-related molecules and processes (2nd edition).
-
Klionsky, D. J., Baehrecke, E. H., Brumell, J. H., Chu, C. T., Codogno, P., Cuervo, A. M., et al. (2011). A comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy 7, 1273-1294.
-
(2011)
Autophagy
, vol.7
, pp. 1273-1294
-
-
Klionsky, D.J.1
Baehrecke, E.H.2
Brumell, J.H.3
Chu, C.T.4
Codogno, P.5
Cuervo, A.M.6
-
38
-
-
24144497601
-
Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.
-
Ko, H. S., Von Coelln, R., Sriram, S. R., Kim, S. W., Chung, K. K., Pletnikova, O., et al. (2005). Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death. J. Neurosci. 25, 7968-7978.
-
(2005)
J. Neurosci.
, vol.25
, pp. 7968-7978
-
-
Ko, H.S.1
Von Coelln, R.2
Sriram, S.R.3
Kim, S.W.4
Chung, K.K.5
Pletnikova, O.6
-
39
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice.
-
Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J., Tanida, I., et al. (2006). Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 441, 880-884.
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
-
40
-
-
77949623516
-
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1.
-
doi:10.1371/journal.pone.0009367
-
Krebiehl, G., Ruckerbauer, S., Burbulla, L. F., Kieper, N., Maurer, B., Waak, J., et al. (2010). Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1. PLoS ONE 5:e9367. doi:10.1371/journal.pone.0009367
-
(2010)
PLoS ONE
, vol.5
-
-
Krebiehl, G.1
Ruckerbauer, S.2
Burbulla, L.F.3
Kieper, N.4
Maurer, B.5
Waak, J.6
-
41
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis.
-
Langston, J. W., Ballard, P., Tetrud, J. W., and Irwin, I. (1983). Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219, 979-980.
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
42
-
-
30744443484
-
Dopamine covalently modifies and functionally inactivates parkin.
-
LaVoie, M. J., Ostaszewski, B. L., Weihofen, A., Schlossmacher, M. G., and Selkoe, D. J. (2005). Dopamine covalently modifies and functionally inactivates parkin. Nat. Med. 11, 1214-1221.
-
(2005)
Nat. Med.
, vol.11
, pp. 1214-1221
-
-
LaVoie, M.J.1
Ostaszewski, B.L.2
Weihofen, A.3
Schlossmacher, M.G.4
Selkoe, D.J.5
-
43
-
-
84873045973
-
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding.
-
Lazarou, M., Narendra, D. P., Jin, S. M., Tekle, E., Banerjee, S., and Youle, R. J. (2013). PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. J. Cell Biol. 200, 163-172.
-
(2013)
J. Cell Biol.
, vol.200
, pp. 163-172
-
-
Lazarou, M.1
Narendra, D.P.2
Jin, S.M.3
Tekle, E.4
Banerjee, S.5
Youle, R.J.6
-
44
-
-
77952326081
-
Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy.
-
Lee, J. Y., Nagano, Y., Taylor, J. P., Lim, K. L., and Yao, T. P. (2010). Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy. J. Cell Biol. 189, 671-679.
-
(2010)
J. Cell Biol.
, vol.189
, pp. 671-679
-
-
Lee, J.Y.1
Nagano, Y.2
Taylor, J.P.3
Lim, K.L.4
Yao, T.P.5
-
45
-
-
16844366524
-
Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging.
-
Lemasters, J. J. (2005). Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging. Rejuvenation Res. 8, 3-5.
-
(2005)
Rejuvenation Res.
, vol.8
, pp. 3-5
-
-
Lemasters, J.J.1
-
46
-
-
37149006535
-
Ubiquitin-proteasome system dysfunction in Parkinson's disease: current evidence and controversies.
-
Lim, K. L. (2007). Ubiquitin-proteasome system dysfunction in Parkinson's disease: current evidence and controversies. Expert Rev. Proteomics 4, 769-781.
-
(2007)
Expert Rev. Proteomics
, vol.4
, pp. 769-781
-
-
Lim, K.L.1
-
47
-
-
20044386298
-
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation.
-
Lim, K. L., Chew, K. C., Tan, J. M., Wang, C., Chung, K. K., Zhang, Y., et al. (2005). Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation. J. Neurosci. 25, 2002-2009.
-
(2005)
J. Neurosci.
, vol.25
, pp. 2002-2009
-
-
Lim, K.L.1
Chew, K.C.2
Tan, J.M.3
Wang, C.4
Chung, K.K.5
Zhang, Y.6
-
48
-
-
80055042897
-
Mitochondrial dynamics and Parkinson's disease: focus on parkin.
-
Lim, K. L., Ng, X. H., Grace, L. G., and Yao, T. P. (2012). Mitochondrial dynamics and Parkinson's disease: focus on parkin. Antioxid. Redox Signal. 16, 935-949.
-
(2012)
Antioxid. Redox Signal.
, vol.16
, pp. 935-949
-
-
Lim, K.L.1
Ng, X.H.2
Grace, L.G.3
Yao, T.P.4
-
49
-
-
79151480727
-
Ubiquitin-proteasome system and mitochondria-reciprocity.
-
Livnat-Levanon, N., and Glickman, M. H. (2011). Ubiquitin-proteasome system and mitochondria-reciprocity. Biochim. Biophys. Acta 1809, 80-87.
-
(2011)
Biochim. Biophys. Acta
, vol.1809
, pp. 80-87
-
-
Livnat-Levanon, N.1
Glickman, M.H.2
-
50
-
-
34447621054
-
Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter.
-
Manning-Bog, A. B., Caudle, W. M., Perez, X. A., Reaney, S. H., Paletzki, R., Isla, M. Z., et al. (2007). Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter. Neurobiol. Dis. 27, 141-150.
-
(2007)
Neurobiol. Dis.
, vol.27
, pp. 141-150
-
-
Manning-Bog, A.B.1
Caudle, W.M.2
Perez, X.A.3
Reaney, S.H.4
Paletzki, R.5
Isla, M.Z.6
-
51
-
-
79960361814
-
Recent advances in the genetics of Parkinson's disease.
-
Martin, I., Dawson, V. L., and Dawson, T. M. (2011). Recent advances in the genetics of Parkinson's disease. Annu. Rev. Genomics Hum. Genet. 12, 301-325.
-
(2011)
Annu. Rev. Genomics Hum. Genet.
, vol.12
, pp. 301-325
-
-
Martin, I.1
Dawson, V.L.2
Dawson, T.M.3
-
52
-
-
13944279784
-
Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES-derived cell model of primary parkinsonism.
-
doi:10.1371/journal.pbio.0020327
-
Martinat, C., Shendelman, S., Jonason, A., Leete, T., Beal, M. F., Yang, L., et al. (2004). Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES-derived cell model of primary parkinsonism. PLoS Biol. 2:e327. doi:10.1371/journal.pbio.0020327
-
(2004)
PLoS Biol.
, vol.2
-
-
Martinat, C.1
Shendelman, S.2
Jonason, A.3
Leete, T.4
Beal, M.F.5
Yang, L.6
-
53
-
-
38849174979
-
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.
-
Martinez-Vicente, M., Talloczy, Z., Kaushik, S., Massey, A. C., Mazzulli, J., Mosharov, E. V., et al. (2008). Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. J. Clin. Invest. 118, 777-788.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 777-788
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Kaushik, S.3
Massey, A.C.4
Mazzulli, J.5
Mosharov, E.V.6
-
54
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.
-
Matsuda, N., Sato, S., Shiba, K., Okatsu, K., Saisho, K., Gautier, C. A., et al. (2010). PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J. Cell Biol. 189, 211-221.
-
(2010)
J. Cell Biol.
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
-
55
-
-
0036075892
-
Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat.
-
McCormack, A. L., Thiruchelvam, M., Manning-Bog, A. B., Thiffault, C., Langston, J. W., Cory-Slechta, D. A., et al. (2002). Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiol. Dis. 10, 119-127.
-
(2002)
Neurobiol. Dis.
, vol.10
, pp. 119-127
-
-
McCormack, A.L.1
Thiruchelvam, M.2
Manning-Bog, A.B.3
Thiffault, C.4
Langston, J.W.5
Cory-Slechta, D.A.6
-
56
-
-
24044506249
-
Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress.
-
Menzies, F. M., Yenisetti, S. C., and Min, K. T. (2005). Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress. Curr. Biol. 15, 1578-1582.
-
(2005)
Curr. Biol.
, vol.15
, pp. 1578-1582
-
-
Menzies, F.M.1
Yenisetti, S.C.2
Min, K.T.3
-
57
-
-
24044472010
-
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease.
-
Meulener, M., Whitworth, A. J., Armstrong-Gold, C. E., Rizzu, P., Heutink, P., Wes, P. D., et al. (2005). Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Curr. Biol. 15, 1572-1577.
-
(2005)
Curr. Biol.
, vol.15
, pp. 1572-1577
-
-
Meulener, M.1
Whitworth, A.J.2
Armstrong-Gold, C.E.3
Rizzu, P.4
Heutink, P.5
Wes, P.D.6
-
58
-
-
78650025189
-
Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2.
-
Mortiboys, H., Johansen, K. K., Aasly, J. O., and Bandmann, O. (2010). Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2. Neurology 75, 2017-2020.
-
(2010)
Neurology
, vol.75
, pp. 2017-2020
-
-
Mortiboys, H.1
Johansen, K.K.2
Aasly, J.O.3
Bandmann, O.4
-
59
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
-
Narendra, D., Tanaka, A., Suen, D. F., and Youle, R. J. (2008). Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol. 183, 795-803.
-
(2008)
J. Cell Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
60
-
-
84867269951
-
AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's disease.
-
Ng, C. H., Guan, M. S., Koh, C., Ouyang, X., Yu, F., Tan, E. K., et al. (2012). AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's disease. J. Neurosci. 32, 14311-14317.
-
(2012)
J. Neurosci.
, vol.32
, pp. 14311-14317
-
-
Ng, C.H.1
Guan, M.S.2
Koh, C.3
Ouyang, X.4
Yu, F.5
Tan, E.K.6
-
61
-
-
84863728713
-
Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via dynamin-like protein.
-
Niu, J., Yu, M., Wang, C., and Xu, Z. (2012). Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via dynamin-like protein. J. Neurochem. 122, 650-658.
-
(2012)
J. Neurochem.
, vol.122
, pp. 650-658
-
-
Niu, J.1
Yu, M.2
Wang, C.3
Xu, Z.4
-
62
-
-
84866072587
-
PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria.
-
Okatsu, K., Oka, T., Iguchi, M., Imamura, K., Kosako, H., Tani, N., et al. (2012). PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria. Nat. Commun. 3, 1016.
-
(2012)
Nat. Commun.
, vol.3
, pp. 1016
-
-
Okatsu, K.1
Oka, T.2
Iguchi, M.3
Imamura, K.4
Kosako, H.5
Tani, N.6
-
63
-
-
34548851476
-
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6.
-
Olzmann, J. A., Li, L., Chudaev, M. V., Chen, J., Perez, F. A., Palmiter, R. D., et al. (2007). Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. J. Cell Biol. 178, 1025-1038.
-
(2007)
J. Cell Biol.
, vol.178
, pp. 1025-1038
-
-
Olzmann, J.A.1
Li, L.2
Chudaev, M.V.3
Chen, J.4
Perez, F.A.5
Palmiter, R.D.6
-
64
-
-
27144519984
-
Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction.
-
Park, J., Kim, S. Y., Cha, G. H., Lee, S. B., Kim, S., and Chung, J. (2005). Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction. Gene 361, 133-139.
-
(2005)
Gene
, vol.361
, pp. 133-139
-
-
Park, J.1
Kim, S.Y.2
Cha, G.H.3
Lee, S.B.4
Kim, S.5
Chung, J.6
-
65
-
-
10744224951
-
Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age.
-
Pawlyk, A. C., Giasson, B. I., Sampathu, D. M., Perez, F. A., Lim, K. L., Dawson, V. L., et al. (2003). Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. J. Biol. Chem. 278, 48120-48128.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48120-48128
-
-
Pawlyk, A.C.1
Giasson, B.I.2
Sampathu, D.M.3
Perez, F.A.4
Lim, K.L.5
Dawson, V.L.6
-
66
-
-
23844483173
-
Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease.
-
Peng, J., Stevenson, F. F., Doctrow, S. R., and Andersen, J. K. (2005). Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease. J. Biol. Chem. 280, 29194-29198.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29194-29198
-
-
Peng, J.1
Stevenson, F.F.2
Doctrow, S.R.3
Andersen, J.K.4
-
67
-
-
77955844260
-
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway.
-
doi:10.1371/journal.pone.0010054
-
Poole, A. C., Thomas, R. E., Yu, S., Vincow, E. S., and Pallanck, L. (2010). The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. PLoS ONE 5:e10054. doi:10.1371/journal.pone.0010054
-
(2010)
PLoS ONE
, vol.5
-
-
Poole, A.C.1
Thomas, R.E.2
Yu, S.3
Vincow, E.S.4
Pallanck, L.5
-
68
-
-
33749133430
-
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.
-
Ramirez, A., Heimbach, A., Grundemann, J., Stiller, B., Hampshire, D., Cid, L. P., et al. (2006). Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase. Nat. Genet. 38, 1184-1191.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1184-1191
-
-
Ramirez, A.1
Heimbach, A.2
Grundemann, J.3
Stiller, B.4
Hampshire, D.5
Cid, L.P.6
-
69
-
-
61449175809
-
Evidence that alpha-synuclein does not inhibit phospholipase D.
-
Rappley, I., Gitler, A. D., Selvy, P. E., Lavoie, M. J., Levy, B. D., Brown, H. A., et al. (2009). Evidence that alpha-synuclein does not inhibit phospholipase D. Biochemistry 48, 1077-1083.
-
(2009)
Biochemistry
, vol.48
, pp. 1077-1083
-
-
Rappley, I.1
Gitler, A.D.2
Selvy, P.E.3
Lavoie, M.J.4
Levy, B.D.5
Brown, H.A.6
-
70
-
-
41249090880
-
Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells.
-
Rott, R., Szargel, R., Haskin, J., Shani, V., Shainskaya, A., Manov, I., et al. (2008). Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells. J. Biol. Chem. 283, 3316-3328.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 3316-3328
-
-
Rott, R.1
Szargel, R.2
Haskin, J.3
Shani, V.4
Shainskaya, A.5
Manov, I.6
-
71
-
-
57649148823
-
Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator.
-
Scarpulla, R. C. (2008). Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator. Ann. N. Y. Acad. Sci. 1147, 321-334.
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1147
, pp. 321-334
-
-
Scarpulla, R.C.1
-
72
-
-
0024390719
-
Mitochondrial complex I deficiency in Parkinson's disease.
-
Schapira, A. H., Cooper, J. M., Dexter, D., Jenner, P., Clark, J. B., and Marsden, C. D. (1989). Mitochondrial complex I deficiency in Parkinson's disease. Lancet 1, 1269.
-
(1989)
Lancet
, vol.1
, pp. 1269
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Jenner, P.4
Clark, J.B.5
Marsden, C.D.6
-
73
-
-
79952303794
-
PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease.
-
Shin, J. H., Ko, H. S., Kang, H., Lee, Y., Lee, Y. I., Pletinkova, O., et al. (2011). PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease. Cell 144, 689-702.
-
(2011)
Cell
, vol.144
, pp. 689-702
-
-
Shin, J.H.1
Ko, H.S.2
Kang, H.3
Lee, Y.4
Lee, Y.I.5
Pletinkova, O.6
-
74
-
-
0030612117
-
Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects.
-
Shults, C. W., Haas, R. H., Passov, D., and Beal, M. F. (1997). Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann. Neurol. 42, 261-264.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 261-264
-
-
Shults, C.W.1
Haas, R.H.2
Passov, D.3
Beal, M.F.4
-
75
-
-
0028067656
-
Glutathione-related enzymes in brain in Parkinson's disease.
-
Sian, J., Dexter, D. T., Lees, A. J., Daniel, S., Jenner, P., and Marsden, C. D. (1994). Glutathione-related enzymes in brain in Parkinson's disease. Ann. Neurol. 36, 356-361.
-
(1994)
Ann. Neurol.
, vol.36
, pp. 356-361
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
Daniel, S.4
Jenner, P.5
Marsden, C.D.6
-
76
-
-
0038413759
-
Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function.
-
Snyder, H., Mensah, K., Theisler, C., Lee, J., Matouschek, A., and Wolozin, B. (2003). Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function. J. Biol. Chem. 278, 11753-11759.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11753-11759
-
-
Snyder, H.1
Mensah, K.2
Theisler, C.3
Lee, J.4
Matouschek, A.5
Wolozin, B.6
-
77
-
-
0030882856
-
Alpha-synuclein in Lewy bodies.
-
Spillantini, M. G., Schmidt, M. L., Lee, V. M., Trojanowski, J. Q., Jakes, R., and Goedert, M. (1997). Alpha-synuclein in Lewy bodies. Nature 388, 839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
78
-
-
79961239061
-
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo.
-
Sterky, F. H., Lee, S., Wibom, R., Olson, L., and Larsson, N. G. (2011). Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc. Natl. Acad. Sci. U.S.A. 108, 12937-12942.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 12937-12942
-
-
Sterky, F.H.1
Lee, S.2
Wibom, R.3
Olson, L.4
Larsson, N.G.5
-
79
-
-
67649374865
-
Protein misfolding and aggregation in Parkinson's disease.
-
Tan, J. M., Wong, E. S., and Lim, K. L. (2009). Protein misfolding and aggregation in Parkinson's disease. Antioxid. Redox Signal. 11, 2119-2134.
-
(2009)
Antioxid. Redox Signal.
, vol.11
, pp. 2119-2134
-
-
Tan, J.M.1
Wong, E.S.2
Lim, K.L.3
-
80
-
-
79956323688
-
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy.
-
Thomas, K. J., McCoy, M. K., Blackinton, J., Beilina, A., Van Der Brug, M., Sandebring, A., et al. (2011). DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. Hum. Mol. Genet. 20, 40-50.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 40-50
-
-
Thomas, K.J.1
McCoy, M.K.2
Blackinton, J.3
Beilina, A.4
Van Der Brug, M.5
Sandebring, A.6
-
81
-
-
84858403126
-
Deficiency of ATP13A2 leads to lysosomal dysfunction, alpha-synuclein accumulation, and neurotoxicity.
-
Usenovic, M., Tresse, E., Mazzulli, J. R., Taylor, J. P., and Krainc, D. (2012). Deficiency of ATP13A2 leads to lysosomal dysfunction, alpha-synuclein accumulation, and neurotoxicity. J. Neurosci. 32, 4240-4246.
-
(2012)
J. Neurosci.
, vol.32
, pp. 4240-4246
-
-
Usenovic, M.1
Tresse, E.2
Mazzulli, J.R.3
Taylor, J.P.4
Krainc, D.5
-
82
-
-
29644448325
-
Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function.
-
Wang, C., Ko, H. S., Thomas, B., Tsang, F., Chew, K. C., Tay, S. P., et al. (2005). Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function. Hum. Mol. Genet. 14, 3885-3897.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 3885-3897
-
-
Wang, C.1
Ko, H.S.2
Thomas, B.3
Tsang, F.4
Chew, K.C.5
Tay, S.P.6
-
83
-
-
84859259002
-
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1.
-
Wang, X., Yan, M. H., Fujioka, H., Liu, J., Wilson-Delfosse, A., Chen, S. G., et al. (2012). LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum. Mol. Genet. 21, 1931-1944.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 1931-1944
-
-
Wang, X.1
Yan, M.H.2
Fujioka, H.3
Liu, J.4
Wilson-Delfosse, A.5
Chen, S.G.6
-
84
-
-
0021178713
-
Membrane properties of rat locus coeruleus neurones.
-
Williams, J. T., North, R. A., Shefner, S. A., Nishi, S., and Egan, T. M. (1984). Membrane properties of rat locus coeruleus neurones. Neuroscience 13, 137-156.
-
(1984)
Neuroscience
, vol.13
, pp. 137-156
-
-
Williams, J.T.1
North, R.A.2
Shefner, S.A.3
Nishi, S.4
Egan, T.M.5
-
85
-
-
77957189194
-
alpha-Synuclein impairs macroautophagy: implications for Parkinson's disease.
-
Winslow, A. R., Chen, C. W., Corrochano, S., Acevedo-Arozena, A., Gordon, D. E., Peden, A. A., et al. (2010). alpha-Synuclein impairs macroautophagy: implications for Parkinson's disease. J. Cell Biol. 190, 1023-1037.
-
(2010)
J. Cell Biol.
, vol.190
, pp. 1023-1037
-
-
Winslow, A.R.1
Chen, C.W.2
Corrochano, S.3
Acevedo-Arozena, A.4
Gordon, D.E.5
Peden, A.A.6
-
86
-
-
84864991509
-
Atg9 vesicles are an important membrane source during early steps of autophagosome formation.
-
Yamamoto, H., Kakuta, S., Watanabe, T. M., Kitamura, A., Sekito, T., Kondo-Kakuta, C., et al. (2012). Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J. Cell Biol. 198, 219-233.
-
(2012)
J. Cell Biol.
, vol.198
, pp. 219-233
-
-
Yamamoto, H.1
Kakuta, S.2
Watanabe, T.M.3
Kitamura, A.4
Sekito, T.5
Kondo-Kakuta, C.6
-
87
-
-
26444489693
-
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling.
-
Yang, Y., Gehrke, S., Haque, M. E., Imai, Y., Kosek, J., Yang, L., et al. (2005). Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc. Natl. Acad. Sci. U.S.A. 102, 13670-13675.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 13670-13675
-
-
Yang, Y.1
Gehrke, S.2
Haque, M.E.3
Imai, Y.4
Kosek, J.5
Yang, L.6
-
88
-
-
79957472437
-
Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane.
-
Yoshii, S. R., Kishi, C., Ishihara, N., and Mizushima, N. (2011). Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J. Biol. Chem. 286, 19630-19640.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 19630-19640
-
-
Yoshii, S.R.1
Kishi, C.2
Ishihara, N.3
Mizushima, N.4
-
89
-
-
0032911488
-
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons.
-
Zhang, J., Perry, G., Smith, M. A., Robertson, D., Olson, S. J., Graham, D. G., et al. (1999). Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am. J. Pathol. 154, 1423-1429.
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 1423-1429
-
-
Zhang, J.1
Perry, G.2
Smith, M.A.3
Robertson, D.4
Olson, S.J.5
Graham, D.G.6
-
90
-
-
24944534660
-
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis.
-
Zhang, L., Shimoji, M., Thomas, B., Moore, D. J., Yu, S. W., Marupudi, N. I., et al. (2005). Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Hum. Mol. Genet. 14, 2063-2073.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 2063-2073
-
-
Zhang, L.1
Shimoji, M.2
Thomas, B.3
Moore, D.J.4
Yu, S.W.5
Marupudi, N.I.6
-
91
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin.
-
Ziviani, E., Tao, R. N., and Whitworth, A. J. (2010). Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc. Natl. Acad. Sci. U.S.A. 107, 5018-5023.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
-
92
-
-
2442589922
-
Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A.
-
Zuchner, S., Mersiyanova, I. V., Muglia, M., Bissar-Tadmouri, N., Rochelle, J., Dadali, E. L., et al. (2004). Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat. Genet. 36, 449-451.
-
(2004)
Nat. Genet.
, vol.36
, pp. 449-451
-
-
Zuchner, S.1
Mersiyanova, I.V.2
Muglia, M.3
Bissar-Tadmouri, N.4
Rochelle, J.5
Dadali, E.L.6
|