An Antitubulin Agent BCFMT Inhibits Proliferation of Cancer Cells and Induces Cell Death by Inhibiting Microtubule Dynamics

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Rai, Ankit ^a   Surolia, Avadhesha ^b   Panda, Dulal ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

5 ((5 (2 METHYL 5 NITROPHENYL) FURAN 2 YL)METHYLENE) 2 THIOXOTHIAZOLIDIN 4 ONE; 5 ((5 (4 BROMO 3 CHLOROPHENYL)FURAN 2 YL)METHYLENE) 2 THIOXOTHIAZOLIDIN 4 ONE; 5 (3,5 DICHLORO 4 HYDROXYBENZYLIDENE) 3 PHENYL 2 THIOXOTHIAZOLIDIN N4 ONE; ANTINEOPLASTIC AGENT; BUB1 RELATED PROTEIN; GUANOSINE TRIPHOSPHATASE; HISTONE H3; PROTEIN MAD2; PROTEIN P21; PROTEIN P53; TUBULIN; UNCLASSIFIED DRUG; VINBLASTINE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; BREAST METASTASIS; CANCER CELL; CANCER INHIBITION; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL DEATH; CELL PROLIFERATION; CENTROMERE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG STRUCTURE; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; METAPHASE; MICROTUBULE ASSEMBLY; MITOSIS INDEX; MOUSE; NONHUMAN; OVARY CARCINOMA; POLYMERIZATION; PROTEIN PHOSPHORYLATION; PROTEIN POLYMERIZATION; UTERINE CERVIX CARCINOMA;

ANIMALS; CALCIUM-BINDING PROTEINS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN B1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; KINETOCHORES; MICE; MICROTUBULES; MITOTIC INDEX; NEOPLASMS; POLYMERIZATION; PORPHOBILINOGEN; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; RHODANINE; THIAZOLIDINES; THIONES; TUBULIN; TUBULIN MODULATORS; TUMOR SUPPRESSOR PROTEIN P53; VINBLASTINE;

EID: 84865635380     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044311     Document Type: Article

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