-
1
-
-
0031933224
-
Molecular and cell biology of TGF-beta
-
A.B. Roberts Molecular and cell biology of TGF-beta Miner Electrolyte Metab 24 1998 111 119
-
(1998)
Miner Electrolyte Metab
, vol.24
, pp. 111-119
-
-
Roberts, A.B.1
-
2
-
-
70450187617
-
The regulation of TGFbeta signal transduction
-
A. Moustakas, and C.H. Heldin The regulation of TGFbeta signal transduction Development 136 2009 3699 3714
-
(2009)
Development
, vol.136
, pp. 3699-3714
-
-
Moustakas, A.1
Heldin, C.H.2
-
3
-
-
61749097816
-
TGF-β superfamily signaling in embryonic development and homeostasis
-
M.Y. Wu, and C.S. Hill TGF-β superfamily signaling in embryonic development and homeostasis Dev Cell 16 2009 329 343
-
(2009)
Dev Cell
, vol.16
, pp. 329-343
-
-
Wu, M.Y.1
Hill, C.S.2
-
4
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGFβ receptor for degradation
-
P. Kavsak, R.K. Rasmussen, C.G. Causing, S. Bonni, H. Zhu, and G.H. Thomsen Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGFβ receptor for degradation Mol Cell 6 2000 1365 1375
-
(2000)
Mol Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
-
5
-
-
0035918274
-
Smurf1 interacts with transforming growth factor-beta type i receptor through Smad7 and induces receptor degradation
-
T. Ebisawa, M. Fukuchi, G. Murakami, T. Chiba, K. Tanaka, and T. Imamura Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation J Biol Chem 276 2001 12477 12480
-
(2001)
J Biol Chem
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
Fukuchi, M.2
Murakami, G.3
Chiba, T.4
Tanaka, K.5
Imamura, T.6
-
6
-
-
34249052234
-
TGF-beta in renal injury and disease
-
E.P. Böttinger TGF-beta in renal injury and disease Semin Nephrol 27 2007 309 320
-
(2007)
Semin Nephrol
, vol.27
, pp. 309-320
-
-
Böttinger, E.P.1
-
7
-
-
14844337071
-
Transforming growth factor-beta and Smad signalling in kidney diseases
-
W. Wang, V. Koka, and H.Y. Lan Transforming growth factor-beta and Smad signalling in kidney diseases Nephrology 10 2005 48 56
-
(2005)
Nephrology
, vol.10
, pp. 48-56
-
-
Wang, W.1
Koka, V.2
Lan, H.Y.3
-
8
-
-
84864148484
-
TGF-β/Smad signaling in kidney disease
-
H.Y. Lan, and A.C.K. Chung TGF-β/Smad signaling in kidney disease Semin Nephrol 32 2012 236 243
-
(2012)
Semin Nephrol
, vol.32
, pp. 236-243
-
-
Lan, H.Y.1
Chung, A.C.K.2
-
9
-
-
84872104961
-
Role of the TGF-β/BMP-7/Smad pathways in renal diseases
-
X.M. Meng, A.C.K. Chung, and H.Y. Lan Role of the TGF-β/BMP-7/Smad pathways in renal diseases Clin Sci 124 2013 243 254
-
(2013)
Clin Sci
, vol.124
, pp. 243-254
-
-
Meng, X.M.1
Chung, A.C.K.2
Lan, H.Y.3
-
10
-
-
80052754775
-
Diverse roles of TGF-beta/Smads in renal fibrosis and inflammation
-
H.Y. Lan Diverse roles of TGF-beta/Smads in renal fibrosis and inflammation Int J Biol Sci 7 2011 1056 1067
-
(2011)
Int J Biol Sci
, vol.7
, pp. 1056-1067
-
-
Lan, H.Y.1
-
11
-
-
79959993387
-
Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis
-
C. Medina, M.J. Santos-Martinez, A. Santana, M.C. Paz-Cabrera, M.J. Johnston, and M. Mourelle Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis J Pathol 224 2011 461 472
-
(2011)
J Pathol
, vol.224
, pp. 461-472
-
-
Medina, C.1
Santos-Martinez, M.J.2
Santana, A.3
Paz-Cabrera, M.C.4
Johnston, M.J.5
Mourelle, M.6
-
12
-
-
84862785580
-
Diverse roles of TGF-beta receptor II in renal fibrosis and inflammation in vivo and in vitro
-
X.M. Meng, X.R. Huang, J. Xiao, H.Y. Chen, X. Zhong, and A.C.K. Chung Diverse roles of TGF-beta receptor II in renal fibrosis and inflammation in vivo and in vitro J Pathol 227 2012 175 188
-
(2012)
J Pathol
, vol.227
, pp. 175-188
-
-
Meng, X.M.1
Huang, X.R.2
Xiao, J.3
Chen, H.Y.4
Zhong, X.5
Chung, A.C.K.6
-
13
-
-
49949092931
-
Mice overexpressing latent TGF-β1 are protected against renal fibrosis in obstructive kidney disease
-
X.R. Huang, A.C.K. Chung, X.J. Wang, K.N. Lai, and H.Y. Lan Mice overexpressing latent TGF-β1 are protected against renal fibrosis in obstructive kidney disease Am J Physiol Renal Physiol 295 2008 F118 F127
-
(2008)
Am J Physiol Renal Physiol
, vol.295
-
-
Huang, X.R.1
Chung, A.C.K.2
Wang, X.J.3
Lai, K.N.4
Lan, H.Y.5
-
14
-
-
0346727324
-
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
-
M. Sato, Y. Muragaki, S. Saika, A.B. Roberts, and A. Ooshima Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction J Clin Invest 112 2003 1486 1494
-
(2003)
J Clin Invest
, vol.112
, pp. 1486-1494
-
-
Sato, M.1
Muragaki, Y.2
Saika, S.3
Roberts, A.B.4
Ooshima, A.5
-
15
-
-
0037498439
-
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model
-
H.Y. Lan, W. Mu, N. Tomita, X.R. Huang, J.H. Li, and H.-J. Zhu Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model J Am Soc Nephrol 14 2003 1535 1548
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1535-1548
-
-
Lan, H.Y.1
Mu, W.2
Tomita, N.3
Huang, X.R.4
Li, J.H.5
Zhu, H.-J.6
-
16
-
-
0036181284
-
Gene transfer of Smad7 using electroporation of adenovirus prevents renal fibrosis in post-obstructed kidney
-
Y. Terada, S. Hanada, A. Nakao, M. Kuwahara, S. Sasaki, and F. Marumo Gene transfer of Smad7 using electroporation of adenovirus prevents renal fibrosis in post-obstructed kidney Kidney Int 61 2002 S94 S98
-
(2002)
Kidney Int
, vol.61
-
-
Terada, Y.1
Hanada, S.2
Nakao, A.3
Kuwahara, M.4
Sasaki, S.5
Marumo, F.6
-
17
-
-
65249099522
-
Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice
-
A.C.K. Chung, X.R. Huang, L. Zhou, R. Heuchel, K.N. Lai, and H.Y. Lan Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice Nephrol Dial Transplant 24 2009 1443 1454
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 1443-1454
-
-
Chung, A.C.K.1
Huang, X.R.2
Zhou, L.3
Heuchel, R.4
Lai, K.N.5
Lan, H.Y.6
-
18
-
-
77955489258
-
Essential role for Smad3 in angiotensin II-induced tubular epithelial mesenchymal transition
-
F. Yang, X.R. Huang, A.C.K. Chung, C.-C. Hou, K.N. Lai, and H.Y. Lan Essential role for Smad3 in angiotensin II-induced tubular epithelial mesenchymal transition J Pathol 221 2010 390 401
-
(2010)
J Pathol
, vol.221
, pp. 390-401
-
-
Yang, F.1
Huang, X.R.2
Chung, A.C.K.3
Hou, C.-C.4
Lai, K.N.5
Lan, H.Y.6
-
19
-
-
14644431025
-
Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney
-
C.C. Hou, W. Wang, X.R. Huang, P. Fu, T.H. Chen, and D. Sheikh-Hamad Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney Am J Pathology 166 2005 761 771
-
(2005)
Am J Pathology
, vol.166
, pp. 761-771
-
-
Hou, C.C.1
Wang, W.2
Huang, X.R.3
Fu, P.4
Chen, T.H.5
Sheikh-Hamad, D.6
-
20
-
-
33646794060
-
Essential role of Smad3 in angiotensin II-induced vascular fibrosis
-
W. Wang, X.R. Huang, E. Canlas, K. Oka, L.D. Truong, and C. Deng Essential role of Smad3 in angiotensin II-induced vascular fibrosis Circ Res 98 2006 1032 1039
-
(2006)
Circ Res
, vol.98
, pp. 1032-1039
-
-
Wang, W.1
Huang, X.R.2
Canlas, E.3
Oka, K.4
Truong, L.D.5
Deng, C.6
-
21
-
-
1342268353
-
Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: Implications for diabetic renal and vascular disease
-
J.H. Li, X.R. Huang, H.J. Zhu, M. Oldfield, M. Cooper, and L.D. Truong Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease FASEB J 18 2004 176 178
-
(2004)
FASEB J
, vol.18
, pp. 176-178
-
-
Li, J.H.1
Huang, X.R.2
Zhu, H.J.3
Oldfield, M.4
Cooper, M.5
Truong, L.D.6
-
22
-
-
77949395650
-
Advanced glycation end-products induce tubular CTGF via TGF-β-independent Smad3 signaling
-
A.C.K. Chung, H. Zhang, Y.-Z. Kong, J.-J. Tan, X.R. Huang, and J.B. Kopp Advanced glycation end-products induce tubular CTGF via TGF-β-independent Smad3 signaling J Am Soc Nephrol 21 2010 249 260
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 249-260
-
-
Chung, A.C.K.1
Zhang, H.2
Kong, Y.-Z.3
Tan, J.-J.4
Huang, X.R.5
Kopp, J.B.6
-
23
-
-
0037566734
-
Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy
-
M. Fujimoto, Y. Maezawa, K. Yokote, K. Joh, K. Kobayashi, and H. Kawamura Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy Biochem Biophys Res Commun 305 2003 1002 1007
-
(2003)
Biochem Biophys Res Commun
, vol.305
, pp. 1002-1007
-
-
Fujimoto, M.1
Maezawa, Y.2
Yokote, K.3
Joh, K.4
Kobayashi, K.5
Kawamura, H.6
-
24
-
-
0036387022
-
Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-β-induced fibronectin in mesangial cells
-
M. Isono, S. Chen, S. Won Hong, M. Carmen Iglesias-de la Cruz, and F.N. Ziyadeh Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-β-induced fibronectin in mesangial cells Biochem Biophys Res Commun 296 2002 1356 1365
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 1356-1365
-
-
Isono, M.1
Chen, S.2
Won Hong, S.3
Carmen Iglesias-De La Cruz, M.4
Ziyadeh, F.N.5
-
25
-
-
79551599216
-
The protective role of Smad7 in diabetic kidney disease: Mechanism and therapeutic potential
-
H.Y. Chen, X.R. Huang, W. Wang, J.H. Li, R.L. Heuchel, and A.C.K. Chung The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential Diabetes 60 2011 590 601
-
(2011)
Diabetes
, vol.60
, pp. 590-601
-
-
Chen, H.Y.1
Huang, X.R.2
Wang, W.3
Li, J.H.4
Heuchel, R.L.5
Chung, A.C.K.6
-
26
-
-
77950845870
-
Mechanism of chronic aristolochic acid nephropathy: Role of Smad3
-
L. Zhou, P. Fu, X.R. Huang, F. Liu, A.C.K. Chung, and K.N. Lai Mechanism of chronic aristolochic acid nephropathy: role of Smad3 Am J Physiol Renal Physiol 298 2010 F1006 F1017
-
(2010)
Am J Physiol Renal Physiol
, vol.298
-
-
Zhou, L.1
Fu, P.2
Huang, X.R.3
Liu, F.4
Chung, A.C.K.5
Lai, K.N.6
-
27
-
-
0035827581
-
Functional characterization of transforming growth factor β signaling in Smad2- and Smad3-deficient fibroblasts
-
E. Piek, W.J. Ju, J. Heyer, D. Escalante-Alcalde, C.L. Stewart, and M. Weinstein Functional characterization of transforming growth factor β signaling in Smad2- and Smad3-deficient fibroblasts J Biol Chem.2001 276 1994 5 53
-
(1994)
J Biol Chem.2001
, vol.276
, pp. 5-53
-
-
Piek, E.1
Ju, W.J.2
Heyer, J.3
Escalante-Alcalde, D.4
Stewart, C.L.5
Weinstein, M.6
-
28
-
-
0033602186
-
A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3
-
S. Dennler, S. Huet, and J.M. Gauthier A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3 Oncogene 18 1999 1643 1648
-
(1999)
Oncogene
, vol.18
, pp. 1643-1648
-
-
Dennler, S.1
Huet, S.2
Gauthier, J.M.3
-
29
-
-
0035907240
-
Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach
-
F. Verrecchia, M.L. Chu, and A. Mauviel Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach J Biol Chem 276 2001 17058 17062
-
(2001)
J Biol Chem
, vol.276
, pp. 17058-17062
-
-
Verrecchia, F.1
Chu, M.L.2
Mauviel, A.3
-
30
-
-
30644479959
-
Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation
-
W. Ju, A. Ogawa, J. Heyer, D. Nierhof, L. Yu, and R. Kucherlapati Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation Mol Cell Biol 26 2006 654 667
-
(2006)
Mol Cell Biol
, vol.26
, pp. 654-667
-
-
Ju, W.1
Ogawa, A.2
Heyer, J.3
Nierhof, D.4
Yu, L.5
Kucherlapati, R.6
-
31
-
-
77956548300
-
Smad2 protects against TGF-β/Smad3-mediated renal fibrosis
-
X.M. Meng, X.R. Huang, A.C.K. Chung, W. Qin, X. Shao, and P. Igarashi Smad2 protects against TGF-β/Smad3-mediated renal fibrosis J Am Soc Nephrol 21 2010 1477 1487
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1477-1487
-
-
Meng, X.M.1
Huang, X.R.2
Chung, A.C.K.3
Qin, W.4
Shao, X.5
Igarashi, P.6
-
32
-
-
0036193069
-
Generation of Smad4/Dpc4 conditional knockout mice
-
X. Yang, C. Li, P.L. Herrera, and C.X. Deng Generation of Smad4/Dpc4 conditional knockout mice Genesis 32 2002 80 81
-
(2002)
Genesis
, vol.32
, pp. 80-81
-
-
Yang, X.1
Li, C.2
Herrera, P.L.3
Deng, C.X.4
-
33
-
-
84856691720
-
Disruption of Smad4 impairs TGF-Β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro
-
X.M. Meng, X.R. Huang, J. Xiao, A.C.K. Chung, W. Qin, and H.Y. Chen Disruption of Smad4 impairs TGF-Β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro Kidney Int 81 2012 266 279
-
(2012)
Kidney Int
, vol.81
, pp. 266-279
-
-
Meng, X.M.1
Huang, X.R.2
Xiao, J.3
Chung, A.C.K.4
Qin, W.5
Chen, H.Y.6
-
34
-
-
0034646674
-
Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor β
-
G. von Gersdorff, K. Susztak, F. Rezvani, M. Bitzer, D. Liang, and E.P. Böttinger Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor β J Biol Chem 275 2000 11320 11326
-
(2000)
J Biol Chem
, vol.275
, pp. 11320-11326
-
-
Von Gersdorff, G.1
Susztak, K.2
Rezvani, F.3
Bitzer, M.4
Liang, D.5
Böttinger, E.P.6
-
35
-
-
0033584854
-
Regulation of Smad7 promoter by direct association with Smad3 and Smad4
-
R.P. Nagarajan, J. Zhang, W. Li, and Y. Chen Regulation of Smad7 promoter by direct association with Smad3 and Smad4 J Biol Chem 274 1999 33412 33418
-
(1999)
J Biol Chem
, vol.274
, pp. 33412-33418
-
-
Nagarajan, R.P.1
Zhang, J.2
Li, W.3
Chen, Y.4
-
36
-
-
0034612231
-
Transforming growth factor β-inducible independent binding of SMAD to the Smad7 promoter
-
N.G. Denissova, C. Pouponnot, J. Long, D. He, and F. Liu Transforming growth factor β-inducible independent binding of SMAD to the Smad7 promoter Proc Natl Acad Sci U S A 97 2000 6397 6402
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6397-6402
-
-
Denissova, N.G.1
Pouponnot, C.2
Long, J.3
He, D.4
Liu, F.5
-
37
-
-
0030611757
-
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling
-
A. Nakao, M. Afrakhte, A. Moren, T. Nakayama, J.L. Christian, and R. Heuchel Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling Nature 389 1997 631 635
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
-
38
-
-
42649120148
-
Smad7 as a therapeutic agent for chronic kidney diseases
-
H.Y. Lan Smad7 as a therapeutic agent for chronic kidney diseases Front Biosci 13 2008 4984 4992
-
(2008)
Front Biosci
, vol.13
, pp. 4984-4992
-
-
Lan, H.Y.1
-
39
-
-
39349094176
-
Arkadia regulates TGF-beta signaling during renal tubular epithelial to mesenchymal cell transition
-
F.Y. Liu, X.Z. Li, Y.M. Peng, H. Liu, and Y.H. Liu Arkadia regulates TGF-beta signaling during renal tubular epithelial to mesenchymal cell transition Kidney Int 73 2008 588 594
-
(2008)
Kidney Int
, vol.73
, pp. 588-594
-
-
Liu, F.Y.1
Li, X.Z.2
Peng, Y.M.3
Liu, H.4
Liu, Y.H.5
-
40
-
-
2942535966
-
Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice
-
H. Fukasawa, T. Yamamoto, A. Togawa, N. Ohashi, Y. Fujigaki, and T. Oda Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice Proc Natl Acad Sci U S A 101 2004 8687 8692
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8687-8692
-
-
Fukasawa, H.1
Yamamoto, T.2
Togawa, A.3
Ohashi, N.4
Fujigaki, Y.5
Oda, T.6
-
41
-
-
55449107515
-
Regulation of TGF-beta family signaling by E3 ubiquitin ligases
-
Y. Inoue, and T. Imamura Regulation of TGF-beta family signaling by E3 ubiquitin ligases Cancer Sci 99 2008 2107 2112
-
(2008)
Cancer Sci
, vol.99
, pp. 2107-2112
-
-
Inoue, Y.1
Imamura, T.2
-
42
-
-
0347282737
-
Downregulation of Smad transcriptional corepressors SnoN and Ski in the fibrotic kidney: An amplification mechanism for TGF-β1 signaling
-
J. Yang, X. Zhang, Y. Li, and Y. Liu Downregulation of Smad transcriptional corepressors SnoN and Ski in the fibrotic kidney: an amplification mechanism for TGF-β1 signaling J Am Soc Nephrol 14 2003 3167 3177
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 3167-3177
-
-
Yang, J.1
Zhang, X.2
Li, Y.3
Liu, Y.4
-
43
-
-
45149101298
-
Smad ubiquitination regulatory factor-2 in the fibrotic kidney: Regulation, target specificity, and functional implication
-
R. Tan, W. He, X. Lin, L.P. Kiss, and Y. Liu Smad ubiquitination regulatory factor-2 in the fibrotic kidney: regulation, target specificity, and functional implication Am J Physiol Renal Physiol 294 2008 F1076 F1083
-
(2008)
Am J Physiol Renal Physiol
, vol.294
-
-
Tan, R.1
He, W.2
Lin, X.3
Kiss, L.P.4
Liu, Y.5
-
44
-
-
70349659185
-
Angiotensin II induces connective tissue growth factor and collagen i Expression via transforming growth factor-β-dependent and -independent Smad pathways: The role of Smad3
-
F. Yang, A.C.K. Chung, X.R. Huang, and H.Y. Lan Angiotensin II induces connective tissue growth factor and collagen I Expression via transforming growth factor-β-dependent and -independent Smad pathways: the role of Smad3 Hypertension 54 2009 877 884
-
(2009)
Hypertension
, vol.54
, pp. 877-884
-
-
Yang, F.1
Chung, A.C.K.2
Huang, X.R.3
Lan, H.Y.4
-
45
-
-
80052102044
-
Diabetes complications: The microRNA perspective
-
P. Kantharidis, B. Wang, R.M. Carew, and H.Y. Lan Diabetes complications: the microRNA perspective Diabetes 60 2011 1832 1837
-
(2011)
Diabetes
, vol.60
, pp. 1832-1837
-
-
Kantharidis, P.1
Wang, B.2
Carew, R.M.3
Lan, H.Y.4
-
46
-
-
84873406358
-
Smad7 suppresses renal fibrosis via altering expression of TGF-beta/Smad3-regulated microRNAs
-
A.C. Chung, Y. Dong, W. Yang, X. Zhong, R. Li, and H.Y. Lan Smad7 suppresses renal fibrosis via altering expression of TGF-beta/Smad3-regulated microRNAs Mol Ther 21 2013 388 398
-
(2013)
Mol Ther
, vol.21
, pp. 388-398
-
-
Chung, A.C.1
Dong, Y.2
Yang, W.3
Zhong, X.4
Li, R.5
Lan, H.Y.6
-
47
-
-
77958583070
-
Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-β-induced collagen expression in kidney cells
-
M. Kato, L. Wang, S. Putta, M. Wang, H. Yuan, and G. Sun Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-β-induced collagen expression in kidney cells J Biol Chem 285 2010 34004 34015
-
(2010)
J Biol Chem
, vol.285
, pp. 34004-34015
-
-
Kato, M.1
Wang, L.2
Putta, S.3
Wang, M.4
Yuan, H.5
Sun, G.6
-
48
-
-
80052316668
-
Smad3-mediated upregulation of miR-21 promotes renal fibrosis
-
X. Zhong, A.C.K. Chung, H.Y. Chen, X.M. Meng, and H.Y. Lan Smad3-mediated upregulation of miR-21 promotes renal fibrosis J Am Soc Nephrol 22 2011 1668 1681
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1668-1681
-
-
Zhong, X.1
Chung, A.C.K.2
Chen, H.Y.3
Meng, X.M.4
Lan, H.Y.5
-
50
-
-
84878269299
-
MiR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes
-
X. Zhong, A.C.K. Chung, H.Y. Chen, Y. Dong, X.M. Meng, and R. Li miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes Diabetologia 56 2013 663 674
-
(2013)
Diabetologia
, vol.56
, pp. 663-674
-
-
Zhong, X.1
Chung, A.C.K.2
Chen, H.Y.3
Dong, Y.4
Meng, X.M.5
Li, R.6
-
51
-
-
33847682663
-
MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-β-induced collagen expression via inhibition of E-box repressors
-
M. Kato, J. Zhang, M. Wang, L. Lanting, H. Yuan, and J.J. Rossi MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-β-induced collagen expression via inhibition of E-box repressors Proc Natl Acad Sci U S A 104 2007 3432 3437
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3432-3437
-
-
Kato, M.1
Zhang, J.2
Wang, M.3
Lanting, L.4
Yuan, H.5
Rossi, J.J.6
-
52
-
-
57349186092
-
MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy
-
Q. Wang, Y. Wang, A.W. Minto, J. Wang, Q. Shi, and X. Li MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy FASEB J 22 2008 4126 4135
-
(2008)
FASEB J
, vol.22
, pp. 4126-4135
-
-
Wang, Q.1
Wang, Y.2
Minto, A.W.3
Wang, J.4
Shi, Q.5
Li, X.6
-
53
-
-
78650038626
-
TGF-β-induced MiR-491-5p expression promotes Par-3 degradation in rat proximal tubular epithelial cells
-
Q. Zhou, J. Fan, X. Ding, W. Peng, X. Yu, and Y. Chen TGF-β-induced MiR-491-5p expression promotes Par-3 degradation in rat proximal tubular epithelial cells J Biol Chem 285 2010 40019 40027
-
(2010)
J Biol Chem
, vol.285
, pp. 40019-40027
-
-
Zhou, Q.1
Fan, J.2
Ding, X.3
Peng, W.4
Yu, X.5
Chen, Y.6
-
54
-
-
78650470110
-
MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor β1: A novel role of miR-382
-
A.J. Kriegel, Y. Fang, Y. Liu, Z. Tian, D. Mladinov, and I.R. Matus MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor β1: a novel role of miR-382 Nucleic Acids Res 38 2010 8338 8347
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 8338-8347
-
-
Kriegel, A.J.1
Fang, Y.2
Liu, Y.3
Tian, Z.4
Mladinov, D.5
Matus, I.R.6
-
55
-
-
77649270362
-
High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells
-
B. Du, L.M. Ma, M.B. Huang, H. Zhou, H.L. Huang, and P. Shao High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells FEBS Lett 584 2010 811 816
-
(2010)
FEBS Lett
, vol.584
, pp. 811-816
-
-
Du, B.1
Ma, L.M.2
Huang, M.B.3
Zhou, H.4
Huang, H.L.5
Shao, P.6
-
56
-
-
79960946532
-
TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29
-
W. Qin, A.C.K. Chung, X.R. Huang, X.M. Meng, D.S.C. Hui, and C.M. Yu TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29 J Am Soc Nephrol 22 2011 1462 1474
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1462-1474
-
-
Qin, W.1
Chung, A.C.K.2
Huang, X.R.3
Meng, X.M.4
Hui, D.S.C.5
Yu, C.M.6
-
57
-
-
78751516162
-
MiR-200a prevents renal fibrogenesis through repression of TGF-β2 expression
-
B. Wang, P. Koh, C. Winbanks, M.T. Coughlan, A. McClelland, and A. Watson miR-200a prevents renal fibrogenesis through repression of TGF-β2 expression Diabetes 60 2011 280 287
-
(2011)
Diabetes
, vol.60
, pp. 280-287
-
-
Wang, B.1
Koh, P.2
Winbanks, C.3
Coughlan, M.T.4
McClelland, A.5
Watson, A.6
-
58
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
B.N. Davis, A.C. Hilyard, G. Lagna, and A. Hata SMAD proteins control DROSHA-mediated microRNA maturation Nature 454 2008 56 61
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
59
-
-
77955373730
-
MiR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
-
G. Liu, A. Friggeri, Y. Yang, J. Milosevic, Q. Ding, and V.J. Thannickal miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis J Exp Med 207 2010 1589 1597
-
(2010)
J Exp Med
, vol.207
, pp. 1589-1597
-
-
Liu, G.1
Friggeri, A.2
Yang, Y.3
Milosevic, J.4
Ding, Q.5
Thannickal, V.J.6
-
60
-
-
0030063832
-
Autoimmune manifestations in the transforming growth factor-beta 1 knockout mouse
-
L. Yaswen, A.B. Kulkarni, T. Fredrickson, B. Mittleman, R. Schiffman, and S. Payne Autoimmune manifestations in the transforming growth factor-beta 1 knockout mouse Blood 87 1996 1439 1445
-
(1996)
Blood
, vol.87
, pp. 1439-1445
-
-
Yaswen, L.1
Kulkarni, A.B.2
Fredrickson, T.3
Mittleman, B.4
Schiffman, R.5
Payne, S.6
-
61
-
-
33748448717
-
Transforming growth factor-β Controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms
-
M.O. Li, S. Sanjabi, and R.A. Flavell Transforming growth factor-β Controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms Immunity 25 2006 455 471
-
(2006)
Immunity
, vol.25
, pp. 455-471
-
-
Li, M.O.1
Sanjabi, S.2
Flavell, R.A.3
-
62
-
-
34248592104
-
T Cell-produced transforming growth factor-β1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation
-
M.O. Li, Y.Y. Wan, and R.A. Flavell T Cell-produced transforming growth factor-β1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation Immunity 26 2007 579 591
-
(2007)
Immunity
, vol.26
, pp. 579-591
-
-
Li, M.O.1
Wan, Y.Y.2
Flavell, R.A.3
-
63
-
-
23944486004
-
Signaling mechanism of TGF-β1 in prevention of renal inflammation: Role of Smad7
-
W. Wang, X.R. Huang, A.G. Li, F. Liu, J.-H. Li, and L.D. Truong Signaling mechanism of TGF-β1 in prevention of renal inflammation: role of Smad7 J Am Soc Nephrol 16 2005 1371 1383
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1371-1383
-
-
Wang, W.1
Huang, X.R.2
Li, A.G.3
Liu, F.4
Li, J.-H.5
Truong, L.D.6
-
64
-
-
39049125285
-
Latent TGF-β1 protects against crescentic glomerulonephritis
-
X.R. Huang, A.C.K. Chung, L. Zhou, X.J. Wang, and H.Y. Lan Latent TGF-β1 protects against crescentic glomerulonephritis J Am Soc Nephrol 19 2008 233 242
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 233-242
-
-
Huang, X.R.1
Chung, A.C.K.2
Zhou, L.3
Wang, X.J.4
Lan, H.Y.5
-
65
-
-
0035865213
-
Blockade of TGF-β signaling in T cells prevents the development of experimental glomerulonephritis
-
Y. Kanamaru, A. Nakao, M. Mamura, Y. Suzuki, I. Shirato, and K. Okumura Blockade of TGF-β signaling in T cells prevents the development of experimental glomerulonephritis J Immunol 166 2001 2818 2823
-
(2001)
J Immunol
, vol.166
, pp. 2818-2823
-
-
Kanamaru, Y.1
Nakao, A.2
Mamura, M.3
Suzuki, Y.4
Shirato, I.5
Okumura, K.6
-
66
-
-
0034827951
-
Transforming growth factor-beta2 antibody attenuates fibrosis in the experimental diabetic rat kidney
-
C. Hill, A. Flyvbjerg, R. Rasch, M. Bak, and A. Logan Transforming growth factor-beta2 antibody attenuates fibrosis in the experimental diabetic rat kidney J Endocrinol 170 2001 647 651
-
(2001)
J Endocrinol
, vol.170
, pp. 647-651
-
-
Hill, C.1
Flyvbjerg, A.2
Rasch, R.3
Bak, M.4
Logan, A.5
-
67
-
-
33847011714
-
Evidence for a role of transforming growth factor (TGF)-β1 in the induction of postglomerular albuminuria in diabetic nephropathy:amelioration by soluble TGF-β type II receptor
-
L.M. Russo, E. del Re, D. Brown, and H.Y. Lin Evidence for a role of transforming growth factor (TGF)-β1 in the induction of postglomerular albuminuria in diabetic nephropathy:amelioration by soluble TGF-β type II receptor Diabetes 56 2007 380 388
-
(2007)
Diabetes
, vol.56
, pp. 380-388
-
-
Russo, L.M.1
Del Re, E.2
Brown, D.3
Lin, H.Y.4
-
68
-
-
40049099699
-
Oral administration of GW788388, an inhibitor of TGF-beta type i and II receptor kinases, decreases renal fibrosis
-
M. Petersen, M. Thorikay, M. Deckers, M. van Dinther, E.T. Grygielko, and F. Gellibert Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis Kidney Int 73 2008 705 715
-
(2008)
Kidney Int
, vol.73
, pp. 705-715
-
-
Petersen, M.1
Thorikay, M.2
Deckers, M.3
Van Dinther, M.4
Grygielko, E.T.5
Gellibert, F.6
-
69
-
-
33748939751
-
IN-1130, a novel transforming growth factor-beta type i receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy
-
J.A. Moon, H.T. Kim, I.S. Cho, Y.Y. Sheen, and D.K. Kim IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy Kidney Int 70 2006 1234 1243
-
(2006)
Kidney Int
, vol.70
, pp. 1234-1243
-
-
Moon, J.A.1
Kim, H.T.2
Cho, I.S.3
Sheen, Y.Y.4
Kim, D.K.5
-
70
-
-
77957573525
-
Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy
-
J. Li, X. Qu, J. Yao, G. Caruana, S.D. Ricardo, and Y. Yamamoto Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy Diabetes 59 2010 2612 2624
-
(2010)
Diabetes
, vol.59
, pp. 2612-2624
-
-
Li, J.1
Qu, X.2
Yao, J.3
Caruana, G.4
Ricardo, S.D.5
Yamamoto, Y.6
-
71
-
-
84856753646
-
Asiatic acid inhibits liver fibrosis by blocking TGF-beta/Smad signaling in vivo and in vitro
-
L.X. Tang, R.H. He, G. Yang, J.J. Tan, L. Zhou, and X.M. Meng Asiatic acid inhibits liver fibrosis by blocking TGF-beta/Smad signaling in vivo and in vitro PLoS One 7 2012 e31350
-
(2012)
PLoS One
, vol.7
, pp. 31350
-
-
Tang, L.X.1
He, R.H.2
Yang, G.3
Tan, J.J.4
Zhou, L.5
Meng, X.M.6
|