-
1
-
-
0034785407
-
Transforming growth factor-beta, basement membrane, and epithelial-mesenchymal transdifferentiation: Implications for Fibrosis in Kidney Disease
-
Stahl P.J., Felsen D.: Transforming growth factor-beta, basement membrane, and epithelial-mesenchymal transdifferentiation: Implications for fibrosis in kidney disease. Am J Pathol 159: 1187-1192, 2001 (Pubitemid 32947947)
-
(2001)
American Journal of Pathology
, vol.159
, Issue.4
, pp. 1187-1192
-
-
Stahl, P.J.1
Felsen, D.2
-
2
-
-
0032512094
-
Pathophysiology of progressive nephropathies
-
DOI 10.1056/NEJM199811123392007
-
Remuzzi G., Bertani T.: Pathophysiology of progressive nephropathies. N Engl J Med 339: 1448-1456, 1998 (Pubitemid 28516069)
-
(1998)
New England Journal of Medicine
, vol.339
, Issue.20
, pp. 1448-1456
-
-
Remuzzi, G.1
Bertani, T.2
-
4
-
-
0033658775
-
The importance of tubulointerstitial damage in progressive renal disease
-
Muller G.A., Zeisberg M., Strutz F.: The importance of tubulointerstitial damage in progressive renal disease. Nephrol Dial Transplant 15[Suppl 6]: 76-77, 2000
-
(2000)
Nephrol Dial Transplant
, vol.15
, Issue.SUPPL. 6
, pp. 76-77
-
-
Muller, G.A.1
Zeisberg, M.2
Strutz, F.3
-
5
-
-
78049369136
-
Renal fibrosis: Novel insights into mechanisms and therapeutic targets
-
Boor P., Ostendorf T., Floege J.: Renal fibrosis: Novel insights into mechanisms and therapeutic targets. Nat Rev Nephrol 6: 643-656, 2010
-
(2010)
Nat Rev Nephrol
, vol.6
, pp. 643-656
-
-
Boor, P.1
Ostendorf, T.2
Floege, J.3
-
6
-
-
3543150126
-
High ambient glucose enhances sensitivity to TGF-beta1 via extracellular signal-regulated kinase and protein kinase Cdelta activities in human mesangial cells
-
DOI 10.1097/01.ASN.0000133198.74973.60
-
Hayashida T., Schnaper H.W.: High ambient glucose enhances sensitivity to TGF-beta1 via extracellular signal-regulated kinase and protein kinase Cdelta activities in human mesangial cells. J Am Soc Nephrol 15: 2032-2041, 2004 (Pubitemid 39031342)
-
(2004)
Journal of the American Society of Nephrology
, vol.15
, Issue.8
, pp. 2032-2041
-
-
Hayashida, T.1
Schnaper, H.W.2
-
9
-
-
34250770436
-
Transforming growth factor-beta and microRNA:mRNA regulatory networks in epithelial plasticity
-
DOI 10.1159/000101316
-
Zavadil J., Narasimhan M., Blumenberg M., Schneider R.J.: Transforming growth factor-beta and microRNA:MRNA regulatory networks in epithelial plasticity. Cells Tissues Organs 185: 157-161, 2007 (Pubitemid 46956856)
-
(2007)
Cells Tissues Organs
, vol.185
, Issue.1-3
, pp. 157-161
-
-
Zavadil, J.1
Narasimhan, M.2
Blumenberg, M.3
Schneider, R.J.4
-
10
-
-
33847682663
-
MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors
-
DOI 10.1073/pnas.0611192104
-
Kato M., Zhang J., Wang M., Lanting L., Yuan H., Rossi J.J., Natarajan R.: MicroRNA-192 in diabetic kidney glomeruli and its function in TGFbeta- induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci U S A 104: 3432-3437, 2007 (Pubitemid 46364176)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.9
, pp. 3432-3437
-
-
Kato, M.1
Zhang, J.2
Wang, M.3
Lanting, L.4
Yuan, H.5
Rossi, J.J.6
Natarajan, R.7
-
11
-
-
77955611511
-
MiR-192 mediates TGF-beta/ Smad3-driven renal fibrosis
-
Chung A.C., Huang X.R., Meng X., Lan H.Y.: miR-192 mediates TGF-beta/ Smad3-driven renal fibrosis. J Am Soc Nephrol 21: 1317-1325, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1317-1325
-
-
Chung, A.C.1
Huang, X.R.2
Meng, X.3
Lan, H.Y.4
-
12
-
-
77956921020
-
MicroRNA-21: From cancer to cardiovascular disease
-
Jazbutyte V., Thum T.: MicroRNA-21: From cancer to cardiovascular disease. Curr Drug Targets 11: 926-935, 2010
-
(2010)
Curr Drug Targets
, vol.11
, pp. 926-935
-
-
Jazbutyte, V.1
Thum, T.2
-
13
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
DOI 10.1038/nature07086, PII NATURE07086
-
Davis B.N., Hilyard A.C., Lagna G., Hata A.: SMAD proteins control DROSHA-mediated microRNA maturation. Nature 454: 56-61, 2008 (Pubitemid 351931982)
-
(2008)
Nature
, vol.454
, Issue.7200
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
14
-
-
77955484492
-
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
-
Davis B.N., Hilyard A.C., Nguyen P.H., Lagna G., Hata A.: Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Mol Cell 39: 373-384, 2010
-
(2010)
Mol Cell
, vol.39
, pp. 373-384
-
-
Davis, B.N.1
Hilyard, A.C.2
Nguyen, P.H.3
Lagna, G.4
Hata, A.5
-
15
-
-
22244467087
-
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
-
DOI 10.1158/0008-5472.CAN-05-0137
-
Chan J.A., Krichevsky A.M., Kosik K.S.: MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65: 6029-6033, 2005 (Pubitemid 40994386)
-
(2005)
Cancer Research
, vol.65
, Issue.14
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
16
-
-
57749168828
-
MicroRNA- 21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
-
Thum T., Gross C., Fiedler J., Fischer T., Kissler S., Bussen M., Galuppo P., Just S., Rottbauer W., Frantz S., Castoldi M., Soutschek J., Koteliansky V., Rosenwald A., Basson M.A., Licht J.D., Pena J.T., Rouhanifard S.H., Muckenthaler M.U., Tuschl T., Martin G.R., Bauersachs J., Engelhardt S.: MicroRNA- 21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456: 980-984, 2008
-
(2008)
Nature
, vol.456
, pp. 980-984
-
-
Thum, T.1
Gross, C.2
Fiedler, J.3
Fischer, T.4
Kissler, S.5
Bussen, M.6
Galuppo, P.7
Just, S.8
Rottbauer, W.9
Frantz, S.10
Castoldi, M.11
Soutschek, J.12
Koteliansky, V.13
Rosenwald, A.14
Basson, M..A.15
Licht, J.D.16
Pena, J.T.17
Rouhanifard, S.H.18
Muckenthaler, M.U.19
Tuschl, T.20
Martin, G.R.21
Bauersachs, J.22
Engelhardt, S.23
more..
-
17
-
-
77955373730
-
MiR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
-
Liu G., Friggeri A., Yang Y., Milosevic J., Ding Q., Thannickal V.J., Kaminski N., Abraham E.: miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. J Exp Med 207: 1589-1597, 2010
-
(2010)
J Exp Med
, vol.207
, pp. 1589-1597
-
-
Liu, G.1
Friggeri, A.2
Yang, Y.3
Milosevic, J.4
Ding, Q.5
Thannickal, V.J.6
Kaminski, N.7
Abraham, E.8
-
18
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
DOI 10.1038/ncb1722, PII NCB1722
-
Gregory P.A., Bert A.G., Paterson E.L., Barry S.C., Tsykin A., Farshid G., Vadas M.A., Khew-Goodall Y., Goodall G.J.: The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10: 593-601, 2008 (Pubitemid 351627379)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.5
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
Vadas, M.A.7
Khew-Goodall, Y.8
Goodall, G.J.9
-
19
-
-
51349141401
-
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
-
Van Rooij E., Sutherland L.B., Thatcher J.E., DiMaio J.M., Naseem R.H., Marshall W.S., Hill J.A., Olson E.N.: Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A 105: 13027-13032, 2008
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13027-13032
-
-
Van Rooij, E.1
Sutherland, L.B.2
Thatcher, J.E.3
DiMaio, J.M.4
Naseem, R.H.5
Marshall, W.S.6
Hill, J.A.7
Olson, E.N.8
-
20
-
-
78751476297
-
Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis
-
Roderburg C., Urban G.W., Bettermann K., Vucur M., Zimmermann H., Schmidt S., Janssen J., Koppe C., Knolle P., Castoldi M., Tacke F., Trautwein C., Luedde, T.: Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis. Hepatology 53: 209-218, 2010
-
(2010)
Hepatology
, vol.53
, pp. 209-218
-
-
Roderburg, C.1
Urban, G.W.2
Bettermann, K.3
Vucur, M.4
Zimmermann, H.5
Schmidt, S.6
Janssen, J.7
Koppe, C.8
Knolle, P.9
Castoldi, M.10
Tacke, F.11
Trautwein, C.12
Luedde, T.13
-
21
-
-
70349659185
-
Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: The role of Smad3
-
Yang F., Chung A.C., Huang X.R., Lan H.Y.: Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: The role of Smad3. Hypertension 54: 877-884, 2009
-
(2009)
Hypertension
, vol.54
, pp. 877-884
-
-
Yang, F.1
Chung, A.C.2
Huang, X.R.3
Lan, H.Y.4
-
22
-
-
77950845870
-
Mechanism of chronic aristolochic acid nephropathy: Role of Smad3
-
Zhou L., Fu P., Huang X.R., Liu F., Chung A.C., Lai K.N., Lan H.Y.: Mechanism of chronic aristolochic acid nephropathy: Role of Smad3. Am J Physiol Renal Physiol 298: F1006-F1017, 2010
-
(2010)
Am J Physiol Renal Physiol
, vol.298
-
-
Zhou, L.1
Fu, P.2
Huang, X.R.3
Liu, F.4
Chung, A.C.5
Lai, K.N.6
Lan, H.Y.7
-
23
-
-
77949395650
-
Advanced glycation end-products induce tubular CTGF via TGF-betaindependent Smad3 signaling
-
Chung A.C., Zhang H., Kong Y.Z., Tan J.J., Huang X.R., Kopp J.B., Lan H.Y.: Advanced glycation end-products induce tubular CTGF via TGF-betaindependent Smad3 signaling. J Am Soc Nephrol 21: 249-260, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 249-260
-
-
Chung, A.C.1
Zhang, H.2
Kong, Y.Z.3
Tan, J.J.4
Huang, X.R.5
Kopp, J.B.6
Lan, H.Y.7
-
24
-
-
0035827581
-
Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts
-
Piek E., Ju W.J., Heyer J., Escalante-Alcalde D., Stewart C.L., Weinstein M., Deng C., Kucherlapati R., Bottinger E.P., Roberts A.B.: Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts. J Biol Chem 276: 19945-19953, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 19945-19953
-
-
Piek, E.1
Ju, W.J.2
Heyer, J.3
Escalante-Alcalde, D.4
Stewart, C.L.5
Weinstein, M.6
Deng, C.7
Kucherlapati, R.8
Bottinger, E.P.9
Roberts, A.B.10
-
25
-
-
0346727324
-
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
-
DOI 10.1172/JCI200319270
-
Sato M., Muragaki Y., Saika S., Roberts A.B., Ooshima A.: Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112: 1486-1494, 2003 (Pubitemid 38056275)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.10
, pp. 1486-1494
-
-
Sato, M.1
Muragaki, Y.2
Saika, S.3
Roberts, A.B.4
Ooshima, A.5
-
26
-
-
77956548300
-
Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis
-
Meng X.M., Huang X.R., Chung A.C., Qin W., Shao X., Igarashi P., Ju W., Bottinger E.P., Lan H.Y.: Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis. J Am Soc Nephrol 21: 1477-1487, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1477-1487
-
-
Meng, X.M.1
Huang, X.R.2
Chung, A.C.3
Qin, W.4
Shao, X.5
Igarashi, P.6
Ju, W.7
Bottinger, E.P.8
Lan, H.Y.9
-
27
-
-
67349254469
-
MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells
-
Li T., Li D., Sha J., Sun P., Huang Y.: MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. Biochem Biophys Res Commun 383: 280-285, 2009
-
(2009)
Biochem Biophys Res Commun
, vol.383
, pp. 280-285
-
-
Li, T.1
Li, D.2
Sha, J.3
Sun, P.4
Huang, Y.5
-
28
-
-
38149042783
-
Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
-
Frankel L.B., Christoffersen N.R., Jacobsen A., Lindow M., Krogh A., Lund A.H.: Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 283: 1026-1033, 2008
-
(2008)
J Biol Chem
, vol.283
, pp. 1026-1033
-
-
Frankel, L.B.1
Christoffersen, N.R.2
Jacobsen, A.3
Lindow, M.4
Krogh, A.5
Lund, A.H.6
-
29
-
-
77952963826
-
Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3
-
Zhou X., Zhang J., Jia Q., Ren Y., Wang Y., Shi L., Liu N., Wang G., Pu P., You Y., Kang C.: Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3. Oncol Rep 24: 195-201, 2010
-
(2010)
Oncol Rep
, vol.24
, pp. 195-201
-
-
Zhou, X.1
Zhang, J.2
Jia, Q.3
Ren, Y.4
Wang, Y.5
Shi, L.6
Liu, N.7
Wang, G.8
Pu, P.9
You, Y.10
Kang, C.11
-
30
-
-
15944368868
-
Blockade of NFkappaB activation and renal inflammation by ultrasound-mediated gene transfer of Smad7 in rat remnant kidney
-
Ng Y.Y., Hou C.C., Wang W., Huang X.R., Lan, H.Y.: Blockade of NFkappaB activation and renal inflammation by ultrasound-mediated gene transfer of Smad7 in rat remnant kidney. Kidney Int Suppl: S83-S91, 2005
-
(2005)
Kidney Int Suppl
-
-
Ng, Y.Y.1
Hou, C.C.2
Wang, W.3
Huang, X.R.4
Lan, H.Y.5
-
31
-
-
0037498439
-
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model
-
DOI 10.1097/01.ASN.0000067632.04658.B8
-
Lan H.Y., Mu W., Tomita N., Huang X.R., Li J.H., Zhu H.J., Morishita R., Johnson R.J.: Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol 14: 1535-1548, 2003 (Pubitemid 36687055)
-
(2003)
Journal of the American Society of Nephrology
, vol.14
, Issue.6
, pp. 1535-1548
-
-
Lan, H.Y.1
Mu, W.2
Tomita, N.3
Huang, X.R.4
Li, J.H.5
Zhu, H.-J.6
Morishita, R.7
Johnson, R.J.8
-
32
-
-
14644431025
-
Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney
-
Hou C.C., Wang W., Huang X.R., Fu P., Chen T.H., Sheikh-Hamad D., Lan H.Y.: Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney. Am J Pathol 166: 761-771, 2005 (Pubitemid 40315633)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.3
, pp. 761-771
-
-
Hou, C.-C.1
Wang, W.2
Huang, X.R.3
Fu, P.4
Chen, T.-H.5
Sheikh-Hamad, D.6
Lan, H.Y.7
-
33
-
-
34249895264
-
Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice
-
Ka S.M., Huang X.R., Lan H.Y., Tsai P.Y., Yang S.M., Shui H.A., Chen A.: Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice. J Am Soc Nephrol 18: 1777-1788, 2007
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1777-1788
-
-
Ka, S.M.1
Huang, X.R.2
Lan, H.Y.3
Tsai, P.Y.4
Yang, S.M.5
Shui, H.A.6
Chen, A.7
-
34
-
-
0038717407
-
BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
-
DOI 10.1038/nm888
-
Zeisberg M., Hanai J., Sugimoto H., Mammoto T., Charytan D., Strutz F., Kalluri R.: BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 9: 964-968, 2003 (Pubitemid 36889942)
-
(2003)
Nature Medicine
, vol.9
, Issue.7
, pp. 964-968
-
-
Zeisberg, M.1
Hanai, J.-I.2
Sugimoto, H.3
Mammoto, T.4
Charytan, D.5
Strutz, F.6
Kalluri, R.7
-
35
-
-
58149247876
-
Mechanisms of kidney fibrosis and the role of antifibrotic therapies
-
Deelman L., Sharma K.: Mechanisms of kidney fibrosis and the role of antifibrotic therapies. Curr Opin Nephrol Hypertens 18: 85-90, 2009
-
(2009)
Curr Opin Nephrol Hypertens
, vol.18
, pp. 85-90
-
-
Deelman, L.1
Sharma, K.2
-
36
-
-
15844402989
-
Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect
-
DOI 10.1111/j.1523-1755.2004.00901.x
-
Yu L., Border W.A., Anderson I., McCourt M., Huang Y., Noble N.A.: Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect. Kidney Int 66: 1774-1784, 2004 (Pubitemid 41094301)
-
(2004)
Kidney International
, vol.66
, Issue.5
, pp. 1774-1784
-
-
Yu, L.1
Border, W.A.2
Anderson, I.3
McCourt, M.4
Huang, Y.5
Noble, N.A.6
-
37
-
-
0030063832
-
Autoimmune manifestations in the transforming growth factor-beta1 knockout mouse
-
Yaswen L., Kulkarni A.B., Fredrickson T., Mittleman B., Schiffman R., Payne S., Longenecker G., Mozes E., Karlsson S.: Autoimmune manifestations in the transforming growth factor-beta 1 knockout mouse. Blood 87: 1439-1445, 1996 (Pubitemid 26056908)
-
(1996)
Blood
, vol.87
, Issue.4
, pp. 1439-1445
-
-
Yaswen, L.1
Kulkarni, A.B.2
Fredrickson, T.3
Mittleman, B.4
Schiffmann, R.5
Payne, S.6
Longenecker, G.7
Mozes, E.8
Karlsson, S.9
-
38
-
-
77956279443
-
Identification of a microRNA signature of renal ischemia reperfusion injury
-
Godwin J.G., Ge X., Stephan K., Jurisch A., Tullius S.G., Iacomini J.: Identification of a microRNA signature of renal ischemia reperfusion injury. Proc Natl Acad Sci U S A 107: 14339-14344, 2010
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 14339-14344
-
-
Godwin, J.G.1
Ge, X.2
Stephan, K.3
Jurisch, A.4
Tullius, S.G.5
Iacomini, J.6
-
39
-
-
62349141343
-
MicroRNA expression in response to murine myocardial infarction: MiR-21 regulates fibroblast metalloprotease- 2 via phosphatase and tensin homologue
-
Roy S., Khanna S., Hussain S.R., Biswas S., Azad A., Rink C., Gnyawali S., Shilo S., Nuovo G.J., Sen C.K.: MicroRNA expression in response to murine myocardial infarction: MiR-21 regulates fibroblast metalloprotease- 2 via phosphatase and tensin homologue. Cardiovasc Res 82: 21-29, 2009
-
(2009)
Cardiovasc Res
, vol.82
, pp. 21-29
-
-
Roy, S.1
Khanna, S.2
Hussain, S.R.3
Biswas, S.4
Azad, A.5
Rink, C.6
Gnyawali, S.7
Shilo, S.8
Nuovo, G.J.9
Sen, C.K.10
-
40
-
-
30344485686
-
Negative regulation of myofibroblast differentiation by PTEN (phosphatase and tensin homolog deleted on chromosome 10)
-
DOI 10.1164/rccm.200507-1058OC
-
White E.S., Atrasz R.G., Hu B., Phan S.H., Stambolic V., Mak T.W., Hogaboam C.M., Flaherty K.R., Martinez F.J., Kontos C.D., Toews G.B.: Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10). Am J Respir Crit Care Med 173: 112-121, 2006 (Pubitemid 43069796)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.173
, Issue.1
, pp. 112-121
-
-
White, E.S.1
Atrasz, R.G.2
Hu, B.3
Phan, S.H.4
Stambolic, V.5
Mak, T.W.6
Hogaboam, C.M.7
Flaherty, K.R.8
Martinez, F.J.9
Kontos, C.D.10
Toews, G.B.11
-
41
-
-
77954274715
-
E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta
-
Wang B., Herman-Edelstein M., Koh P., Burns W., Jandeleit-Dahm K., Watson A., Saleem M., Goodall G.J., Twigg S.M., Cooper M.E., Kantharidis P.: E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta. Diabetes 59: 1794-1802, 2010
-
(2010)
Diabetes
, vol.59
, pp. 1794-1802
-
-
Wang, B.1
Herman-Edelstein, M.2
Koh, P.3
Burns, W.4
Jandeleit-Dahm, K.5
Watson, A.6
Saleem, M.7
Goodall, G.J.8
Twigg, S.M.9
Cooper, M.E.10
Kantharidis, P.11
-
42
-
-
77949892330
-
Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy
-
Krupa A., Jenkins R., Luo D.D., Lewis A., Phillips A., Fraser, D.: Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy. J Am Soc Nephrol 21: 438-447, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 438-447
-
-
Krupa, A.1
Jenkins, R.2
Luo, D.D.3
Lewis, A.4
Phillips, A.5
Fraser, D.6
-
43
-
-
1342268353
-
Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: Implications for diabetic renal and vascular disease
-
Li J.H., Huang X.R., Zhu H.J., Oldfield M., Cooper M., Truong L.D., Johnson R.J., Lan H.Y.: Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: Implications for diabetic renal and vascular disease. Faseb J 18: 176-178, 2004
-
(2004)
Faseb J
, vol.18
, pp. 176-178
-
-
Li, J.H.1
Huang, X.R.2
Zhu, H.J.3
Oldfield, M.4
Cooper, M.5
Truong, L.D.6
Johnson, R.J.7
Lan, H.Y.8
-
44
-
-
71549128965
-
Knockdown of microRNA-181 by lentivirus mediated siRNA expression vector decreases the arrhythmogenic effect of skeletal myoblast transplantation in rat with myocardial infarction
-
Li Y.G., Zhang P.P., Jiao K.L., Zou Y.Z.: Knockdown of microRNA-181 by lentivirus mediated siRNA expression vector decreases the arrhythmogenic effect of skeletal myoblast transplantation in rat with myocardial infarction. Microvasc Res 78: 393-404, 2009
-
(2009)
Microvasc Res
, vol.78
, pp. 393-404
-
-
Li, Y.G.1
Zhang, P.P.2
Jiao, K.L.3
Zou, Y.Z.4
-
45
-
-
65249099522
-
Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice
-
Chung A.C., Huang X.R., Zhou L., Heuchel R., Lai K.N., Lan H.Y.: Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice. Nephrol Dial Transplant 24: 1443-1454, 2009
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 1443-1454
-
-
Chung, A.C.1
Huang, X.R.2
Zhou, L.3
Heuchel, R.4
Lai, K.N.5
Lan, H.Y.6
-
46
-
-
79551599216
-
The protective role of Smad7 in diabetic kidney disease: Mechanism and therapeutic potential
-
Chen H., Huang X.R., Wang W., Li J., Heuchel R.L., Chung A.C., Lan H.Y.: The protective role of Smad7 in diabetic kidney disease: Mechanism and therapeutic potential. Diabetes 60: 590-601, 2010
-
(2010)
Diabetes
, vol.60
, pp. 590-601
-
-
Chen, H.1
Huang, X.R.2
Wang, W.3
Li, J.4
Heuchel, R.L.5
Chung, A.C.6
Lan, H.Y.7
-
47
-
-
0033104503
-
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta
-
Yang X., Letterio J.J., Lechleider R.J., Chen L., Hayman R., Gu H., Roberts A.B., Deng C.: Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. EMBO J 18: 1280-1291, 1999 (Pubitemid 29110312)
-
(1999)
EMBO Journal
, vol.18
, Issue.5
, pp. 1280-1291
-
-
Yang, X.1
Letterio, J.J.2
Lechleider, R.J.3
Chen, L.4
Hayman, R.5
Gu, H.6
Roberts, A.B.7
Deng, C.8
-
48
-
-
30644479959
-
Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation
-
DOI 10.1128/MCB.26.2.654-667.2006
-
Ju W., Ogawa A., Heyer J., Nierhof D., Yu L., Kucherlapati R., Shafritz D.A., Bottinger E.P.: Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation. Mol Cell Biol 26: 654-667, 2006 (Pubitemid 43089776)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.2
, pp. 654-667
-
-
Ju, W.1
Ogawa, A.2
Heyer, J.3
Nierhof, D.4
Yu, L.5
Kucherlapati, R.6
Shafritz, D.A.7
Bottinger, E.P.8
-
49
-
-
43449084360
-
Angiotensin II up-regulates Angiotensin I-Converting Enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway
-
DOI 10.2353/ajpath.2008.070762
-
Koka V., Huang X.R., Chung A.C., Wang W., Truong L.D., Lan H.Y.: Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway. Am J Pathol 172: 1174-1183, 2008 (Pubitemid 351671532)
-
(2008)
American Journal of Pathology
, vol.172
, Issue.5
, pp. 1174-1183
-
-
Koka, V.1
Xiao, R.H.2
Chung, A.C.K.3
Wang, W.4
Truong, L.D.5
Lan, H.Y.6
-
50
-
-
0030000689
-
A novel method of microwave treatment for detection of cytoplasmic and nuclear antigens by flow cytometry
-
DOI 10.1016/0022-1759(95)00233-2
-
Lan H.Y., Hutchinson P., Tesch G.H., Mu W., Atkins R.C.: A novel method of microwave treatment for detection of cytoplasmic and nuclear antigens by flow cytometry. J Immunol Methods 190: 1-10, 1996 (Pubitemid 26099973)
-
(1996)
Journal of Immunological Methods
, vol.190
, Issue.1
, pp. 1-10
-
-
Lan, H.Y.1
Hutchinson, P.2
Tesch, G.H.3
Mu, W.4
Atkins, R.C.5
-
51
-
-
39049125285
-
Latent TGF-beta1 protects against crescentic glomerulonephritis
-
DOI 10.1681/ASN.2007040484
-
Huang X.R., Chung A.C., Zhou L., Wang X.J., Lan H.Y.: Latent TGF-beta1 protects against crescentic glomerulonephritis. J Am Soc Nephrol 19: 233-242, 2008 (Pubitemid 351240645)
-
(2008)
Journal of the American Society of Nephrology
, vol.19
, Issue.2
, pp. 233-242
-
-
Huang, X.R.1
Chung, A.C.K.2
Zhou, L.3
Wang, X.J.4
Lan, H.Y.5
-
52
-
-
49949092931
-
Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease
-
Huang X.R., Chung A.C., Wang X.J., Lai K.N., Lan H.Y.: Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease. Am J Physiol Renal Physiol 295: F118-F127, 2008
-
(2008)
Am J Physiol Renal Physiol
, vol.295
-
-
Huang, X.R.1
Chung, A.C.2
Wang, X.J.3
Lai, K.N.4
Lan, H.Y.5
-
53
-
-
31344454565
-
In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes
-
DOI 10.1038/nmeth843, PII N843
-
Kloosterman W.P., Wienholds E., De Bruijn E., Kauppinen S., Plasterk R.H.: In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat Methods 3: 27-29, 2006 (Pubitemid 43135345)
-
(2006)
Nature Methods
, vol.3
, Issue.1
, pp. 27-29
-
-
Kloosterman, W.P.1
Wienholds, E.2
De Bruijn, E.3
Kauppinen, S.4
Plasterk, R.H.A.5
-
54
-
-
34250777057
-
Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections
-
DOI 10.1038/nprot.2007.153, PII NPROT.2007.153
-
Obernosterer G., Martinez J., Alenius M.: Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nat Protoc 2: 1508-1514, 2007 (Pubitemid 46952329)
-
(2007)
Nature Protocols
, vol.2
, Issue.6
, pp. 1508-1514
-
-
Obernosterer, G.1
Martinez, J.2
Alenius, M.3
|