Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction

Diabetes

Volumn 62, Issue 6, 2013, Pages 1996-2003

  Sasaki, Mayumi ^a   Fujimoto, Shimpei ^a,b   Sato, Yuichi ^a   Nishi, Yuichi ^a,b   Mukai, Eri ^a   Yamano, Gen ^a   Sato, Hiroki ^a   Tahara, Yumiko ^a   Ogura, Kasane ^a   Nagashima, Kazuaki ^a   Inagaki, Nobuya ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KOCHI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; EBSELEN; GLUCOKINASE; GLUCOSE; HYDROGEN PEROXIDE; LACTIC ACID; OXYGEN; REACTIVE OXYGEN METABOLITE; TEMPOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CITRIC ACID CYCLE; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE OXIDATION; GLYCOLYSIS; GOTO KAKIZAKI RAT; MALE; METABOLISM; MITOCHONDRIAL RESPIRATION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; AZOLES; CELLS, CULTURED; CYCLIC N-OXIDES; DIABETES MELLITUS; GLUCOKINASE; GLUCOSE; GLYCEROL-3-PHOSPHATE DEHYDROGENASE (NAD+); HEXOKINASE; HYDROGEN PEROXIDE; IMMUNOBLOTTING; INSULIN; LACTIC ACID; MALE; ORGANOSELENIUM COMPOUNDS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SPIN LABELS;

EID: 84878233692     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0903     Document Type: Article

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