Chronic exposure to β-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents

American Journal of Physiology - Endocrinology and Metabolism

Volumn 288, Issue 2 51-2, 2005, Pages

  Takehiro, Mihoko ^a   Fujimoto, Shimpei ^a   Shimodahira, Makiko ^a   Shimono, Dai ^a   Mukai, Eri ^a   Nabe, Koichiro ^a   Radu, Razvan Gheorghe ^a   Kominato, Rieko ^a   Aramaki, Yo ^a   Seino, Yutaka ^a,b   Yamada, Yuichiro ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KANSAI DENRYOKU HOSPITAL   (Japan)

Author keywords

Adenosine 5 triphosphate; Islet; Reduced nicotinamide adenine dinucleotide

Indexed keywords

3 HYDROXYBUTYRIC ACID; ADENOSINE TRIPHOSPHATE; BIPHASIC INSULIN; CALCIUM ION; GLUCOSE; INSULIN; KETONE BODY; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SUCCINATE DEHYDROGENASE (UBIQUINONE);

ANIMAL CELL; ARTICLE; BASAL CELL; CALCIUM CELL LEVEL; CALCIUM METABOLISM; CELL CULTURE; CELL METABOLISM; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; EXOCYTOSIS; GLUCOSE OXIDATION; GLUCOSE UTILIZATION; INSULIN RELEASE; LONG TERM EXPOSURE; MALE; MITOCHONDRION; NONHUMAN; NUCLEOTIDE METABOLISM; PANCREAS CELL; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

3-HYDROXYBUTYRIC ACID; ADAPTATION, PHYSIOLOGICAL; ANIMALS; CALCIUM; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INHIBITORS; EXOCYTOSIS; GLUCOSE; INSULIN; ISLETS OF LANGERHANS; MALE; METABOLIC CLEARANCE RATE; NAD; RATS; RATS, WISTAR; TIME FACTORS;

EID: 19944428662     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00157.2004     Document Type: Article

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