Exendin-4 suppresses Src activation and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner

Diabetes

Volumn 60, Issue 1, 2011, Pages 218-226

  Mukai, Eri ^a,b   Fujimoto, Shimpei ^a   Sato, Hiroki ^a   Oneyama, Chitose ^c   Kominato, Rieko ^a   Sato, Yuichi ^a   Sasaki, Mayumi ^a   Nishi, Yuichi ^a   Okada, Masato ^c   Inagaki, Nobuya ^a,d  

^a KYOTO UNIVERSITY   (Japan)

^b Japan Association for the Advancement of Medical Equipment   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; EXENDIN 4; FLUORESCENT DYE; GLUCAGON LIKE PEPTIDE 1; GUANINE NUCLEOTIDE EXCHANGE FACTOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN EPAC; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GOTO KAKIZAKI RAT; IMMUNOBLOTTING; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELLS, CULTURED; HYPOGLYCEMIC AGENTS; IMMUNOBLOTTING; ISLETS OF LANGERHANS; PEPTIDES; PHOSPHORYLATION; RATS; RATS, INBRED STRAINS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SPECIES SPECIFICITY; SRC-FAMILY KINASES; VENOMS;

EID: 78751481226     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-0021     Document Type: Article

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