메뉴 건너뛰기




Volumn 20, Issue 11, 2013, Pages 1409-1436

Transient receptor potential channels-emerging novel drug targets for the treatment of pain

Author keywords

Analgesic Drugs; Hyperthermia; Innocuous And Noxious Cold Detection; Pain Pathways; Polymodal Nociceptor; Transient Receptor Potential Family; Vanilloids

Indexed keywords

(5 TERT BUTYL 2,3 DIHYDRO 1H INDEN 1 YL) 3 (1H INDAZOL 4 YL)UREA; 1 (2 BROMOPHENYL) 3 [1 (5 TRIFLUOROMETHYL 2 PYRIDINYL) 3 PYRROLIDINYL]UREA; 1 (5 ISOQUINOLINYL) 3 [4 (TRIFLUOROMETHYL)BENZYL]UREA; 4 [3 (TRIFLUOROMETHYL) 2 PYRIDINYL] N [5 (TRIFLUOROMETHYL) 2 PYRIDINYL] 1 PIPERAZINECARBOXAMIDE; 4 CHLORO N (3 METHOXYPHENYL)CINNAMAMIDE; A 967079; AMG 0610; AMG 6880; AP 18; AZD 1386; CALCIUM CHANNEL BLOCKING AGENT; CAPSAICIN; CIS CAPSAICIN; GRC 6211; JTS 653; JYL 1421; MK 2295; N (1,4 BENZODIOXAN 6 YL) 3 (4 TERT BUTYLPHENYL)ACRYLAMIDE; N (4 ISOPROPYLPHENYL) 2 (1,2,3,6 TETRAHYDRO 1,3 DIMETHYL 2,6 DIOXO 7H PURIN 7 YL)ACETAMIDE; N [4 [6 [4 (TRIFLUOROMETHYL)PHENYL] 4 PYRIMIDINYLOXY]BENZOTHIAZOL 2 YL]ACETAMIDE; OLVANIL; RESINIFERATOXIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST; VANILLOID RECEPTOR 5; VANILLOID RECEPTOR 6; VANILLOID RECEPTOR AGONIST;

EID: 84877935116     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/09298673113209990107     Document Type: Article
Times cited : (46)

References (121)
  • 1
  • 2
    • 65549133355 scopus 로고    scopus 로고
    • Vanilloid receptor antagonists: Emerging class of novel anti-inflammatory agents for pain management
    • Pal, M.; Angaru, S.; Kodimuthali, A.; Dhingra, N. Vanilloid receptor antagonists: emerging class of novel anti-inflammatory agents for pain management. Curr. Pharm. Des., 2009, 15, 1008-1026.
    • (2009) Curr. Pharm. Des , vol.15 , pp. 1008-1026
    • Pal, M.1    Angaru, S.2    Kodimuthali, A.3    Dhingra, N.4
  • 3
    • 84856409044 scopus 로고    scopus 로고
    • Trpa1 antagonists as potential analgesic drugs
    • Andrade, E.L.; Meotti, F.C.; Calixto, J.B. TRPA1 antagonists as potential analgesic drugs. Pharmacol. Ther., 2012, 133, 189-204.
    • (2012) Pharmacol. Ther , vol.133 , pp. 189-204
    • Andrade, E.L.1    Meotti, F.C.2    Calixto, J.B.3
  • 4
    • 83255182363 scopus 로고    scopus 로고
    • Targeting trpv1: Challenges and issues in pain management
    • Trevisani, M.; Szalassi, A. Targeting TRPV1: Challenges and issues in pain management. Open Drug Discov. J., 2010, 2, 37-49.
    • (2010) Open Drug Discov. J , vol.2 , pp. 37-49
    • Trevisani, M.1    Szalassi, A.2
  • 5
    • 78049420335 scopus 로고    scopus 로고
    • Nociceptors: The sensors of the pain pathway
    • Dubin, A.E.; Patapoutian, A. Nociceptors: the sensors of the pain pathway. J. Clin. Invest., 2010, 120, 3760-3772.
    • (2010) J. Clin. Invest , vol.120 , pp. 3760-3772
    • Dubin, A.E.1    Patapoutian, A.2
  • 6
    • 70349902623 scopus 로고    scopus 로고
    • Transient receptor potential channels on sensory nerves
    • Eid, S.R.; Cortright, D.N. Transient receptor potential channels on sensory nerves. Handb. Exp. Pharmacol., 2009, 194, 261-281.
    • (2009) Handb. Exp. Pharmacol , vol.194 , pp. 261-281
    • Eid, S.R.1    Cortright, D.N.2
  • 7
    • 2942575801 scopus 로고    scopus 로고
    • Acid-sensing ion channels (asics): New targets for the analgesic effects of non-steroid anti-inflammatory drugs (nsaids
    • Voilley, N. Acid-sensing ion channels (ASICs): New targets for the analgesic effects of non-steroid anti-inflammatory drugs (NSAIDs). Curr. Drug Targets Inflamm. Allergy, 2004, 3, 71-79.
    • (2004) Curr. Drug Targets Inflamm. Allergy , vol.3 , pp. 71-79
    • Voilley, N.1
  • 8
    • 0035855860 scopus 로고    scopus 로고
    • Molecular mechanisms of nociception
    • Julius, D.; Basbaum, A.I. Molecular mechanisms of nociception. Nature, 2001, 413, 203-210.
    • (2001) Nature , vol.413 , pp. 203-210
    • Julius, D.1    Basbaum, A.I.2
  • 9
    • 41949127906 scopus 로고    scopus 로고
    • Thermotrp channels in nociceptors: Taking a lead from capsaicin receptor trpv1
    • Mandadi, S.; Roufogalis, B.D ThermoTRP channels in nociceptors: Taking a lead from capsaicin receptor TRPV1. Curr. Neuropharmacol., 2008, 6, 21-38.
    • (2008) Curr. Neuropharmacol , vol.6 , pp. 21-38
    • Mandadi, S.1    Roufogalis, B.D.2
  • 12
    • 61649111137 scopus 로고    scopus 로고
    • Trpv1 receptors in sensitization of cough and pain reflexes
    • Adcock, J.J. TRPV1 receptors in sensitization of cough and pain reflexes. Pulm. Pharmacol. Ther., 2009, 22, 65-70.
    • (2009) Pulm. Pharmacol. Ther , vol.22 , pp. 65-70
    • Adcock, J.J.1
  • 13
    • 0035258219 scopus 로고    scopus 로고
    • Peripheral excitatory amino acids
    • Carlton, S.M. Peripheral excitatory amino acids. Curr. Opin. Pharmacol., 2001, 1, 52-56.
    • (2001) Curr. Opin. Pharmacol , vol.1 , pp. 52-56
    • Carlton, S.M.1
  • 14
    • 24644470357 scopus 로고    scopus 로고
    • Functional aspects and the mechanisms of trpv1 involvement in neurogenic inflammation that leads to thermal hyperalgesia
    • Planells-Cases, R.; Garcia-Sanz, N.; Morenilla-Palao, C.; Ferrer-Montiel, A. Functional aspects and the mechanisms of TRPV1 involvement in neurogenic inflammation that leads to thermal hyperalgesia. Eur. J. Physiol., 2005, 451, 151-159.
    • (2005) Eur. J. Physiol , vol.451 , pp. 151-159
    • Planells-Cases, R.1    Garcia-Sanz, N.2    Morenilla-Palao, C.3    Ferrer-Montiel, A.4
  • 16
    • 70449587066 scopus 로고    scopus 로고
    • Trpv1 and trpa1 mediate peripheral nitric oxide-induced nociception in mice
    • Miyamoto, T.; Dubin, A.E.; Petrus, M.J.; Patapoutian, A. TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice. PLoS One, 2009, 4, e7596.
    • (2009) PLoS One , vol.4
    • Miyamoto, T.1    Dubin, A.E.2    Petrus, M.J.3    Patapoutian, A.4
  • 17
    • 2442608827 scopus 로고    scopus 로고
    • Activation and sensitization of the vanilloid receptor: Role in gastrointestinal inflammation and function
    • Geppetti, P.; Trevisani, M. Activation and sensitization of the vanilloid receptor: Role in gastrointestinal inflammation and function. Br. J. Pharmacol., 2004, 141, 1313-1320.
    • (2004) Br. J. Pharmacol , vol.141 , pp. 1313-1320
    • Geppetti, P.1    Trevisani, M.2
  • 19
    • 79961017633 scopus 로고    scopus 로고
    • The trpv3 receptor as a pain target: A therapeutic promise or just some more new biology?
    • Joshi, N.K.; Maharaj, N.; Thomas, A. The TRPV3 receptor as a pain target: a therapeutic promise or just some more new biology? Open Drug Discov. J., 2010, 2, 89-97.
    • (2010) Open Drug DiscoV. J , vol.2 , pp. 89-97
    • Joshi, N.K.1    Maharaj, N.2    Thomas, A.3
  • 21
    • 70350212466 scopus 로고    scopus 로고
    • The contribution of trpm8 and trpa1 channels to cold allodynia and neuropathic pain
    • Caspani, O.; Zurborg, S.; Labuz, D.; Heppenstall, P.A. The contribution of TRPM8 and TRPA1 channels to cold allodynia and neuropathic pain. PLoS One, 2009, 4, e7383.
    • (2009) PLoS One , vol.4
    • Caspani, O.1    Zurborg, S.2    Labuz, D.3    Heppenstall, P.A.4
  • 22
    • 73549117442 scopus 로고    scopus 로고
    • Differential effects of substance p or hemokinin-1 on transient receptor potential channels, trpv1, trpa1 and trpm8, in the rat
    • Naono-Nakayama, R.; Sunakawa, N.; Ikeda, T.; Nishimori, T. Differential effects of substance P or hemokinin-1 on transient receptor potential channels, TRPV1, TRPA1 and TRPM8, in the rat. Neuropeptides, 2010, 44, 57-61.
    • (2010) Neuropeptides , vol.44 , pp. 57-61
    • Naono-Nakayama, R.1    Sunakawa, N.2    Ikeda, T.3    Nishimori, T.4
  • 23
    • 33746792050 scopus 로고    scopus 로고
    • Neuropathic pain: A practical guide for the clinician
    • Gilron, I.; Pete, C.; Watson, N.; Cahill, C.M.; Moulin, D.E. Neuropathic pain: A practical guide for the clinician. CMAJ, 2006, 175, 265-275.
    • (2006) CMAJ , vol.175 , pp. 265-275
    • Gilron, I.1    Pete, C.2    Watson, N.3    Cahill, C.M.4    Moulin, D.E.5
  • 24
    • 43049098978 scopus 로고    scopus 로고
    • Purinergic p2x receptors presynaptically increase glutamatergic synaptic transmission in dorsolateral periaqueductal gray
    • Xing, J.; Lu, J.; Li, J. Purinergic P2X receptors presynaptically increase glutamatergic synaptic transmission in dorsolateral periaqueductal gray. Brain Res., 2008, 1208, 46-55.
    • (2008) Brain Res , vol.1208 , pp. 46-55
    • Xing, J.1    Lu, J.2    Li, J.3
  • 26
    • 58449106224 scopus 로고    scopus 로고
    • Sb366791, a trpv1 antagonist, potentiates analgesic effects of systemic morphine in a murine model of bone cancer pain
    • Niiyama, Y.; Kawamata, T.; Yamamoto, J.; Furuse, S.; Namiki, A. SB366791, a TRPV1 antagonist, potentiates analgesic effects of systemic morphine in a murine model of bone cancer pain. Br. J. Anaesth., 2009, 102, 251-258.
    • (2009) Br. J. Anaesth , vol.102 , pp. 251-258
    • Niiyama, Y.1    Kawamata, T.2    Yamamoto, J.3    Furuse, S.4    Namiki, A.5
  • 27
    • 78049425093 scopus 로고    scopus 로고
    • The discovery and development of analgesics: New mechanisms, new modalities
    • Burgess, G.; Williams, D. The discovery and development of analgesics: new mechanisms, new modalities. J. Clin. Invest., 2010, 120, 3753-3759.
    • (2010) J. Clin. Invest , vol.120 , pp. 3753-3759
    • Burgess, G.1    Williams, D.2
  • 28
    • 33846797907 scopus 로고    scopus 로고
    • Guide to receptors and channels (grac) 2nd edition (2007 revision
    • Alexander, S.P.; Mathie, A.; Peters, J.A. Guide to receptors and channels (GRAC), 2nd edition (2007 revision). Br. J. Pharmacol., 2007, 150, 1-168.
    • (2007) Br. J. Pharmacol , vol.150 , pp. 1-168
    • Alexander, S.P.1    Mathie, A.2    Peters, J.A.3
  • 29
    • 33749985960 scopus 로고    scopus 로고
    • Cation channels of the transient receptor potential subfamily: Their role in physiological and pathophysiological processes of smooth muscle cells
    • Dietrich, A.; Chubanov, V.; Kalwa, H.; Rost, B.R.; Gudermann, T. Cation channels of the transient receptor potential subfamily: Their role in physiological and pathophysiological processes of smooth muscle cells. Pharmacol. Ther., 2006, 112, 744-760.
    • (2006) Pharmacol. Ther , vol.112 , pp. 744-760
    • Dietrich, A.1    Chubanov, V.2    Kalwa, H.3    Rost, B.R.4    Gudermann, T.5
  • 30
    • 33747624445 scopus 로고    scopus 로고
    • Transient receptor potential channels in cardiovascular function and disease
    • Inoue, R.; Jensen, L.J.; Shi, J.; Morita, H.; Nishida, M.; Honda, A.; Ito, Y. Transient receptor potential channels in cardiovascular function and disease. Circ. Res., 2006, 99, 119-131.
    • (2006) Circ. Res , vol.99 , pp. 119-131
    • Inoue, R.1    Jensen, L.J.2    Shi, J.3    Morita, H.4    Nishida, M.5    Honda, A.6    Ito, Y.7
  • 32
    • 38549118896 scopus 로고    scopus 로고
    • Capsaicin (trpv1 agonist) therapy for pain relief: Farewell or revival?
    • Knotkova, H.; Pappagallo, M.; Szallasi, A. Capsaicin (TRPV1 Agonist) therapy for pain relief: farewell or revival? Clin. J. Pain, 2008, 24, 142-154.
    • (2008) CliN. J. Pain , vol.24 , pp. 142-154
    • Knotkova, H.1    Pappagallo, M.2    Szallasi, A.3
  • 34
    • 77958005885 scopus 로고    scopus 로고
    • Expression of transient receptor potential channel vanilloid (trpv) 1-4, melastin (trpm) 5 and 8, and ankyrin (trpa1) in the normal and methimazole-treated mouse olfactory epithelium
    • Nakashimo, Y.; Takumida, M.; Fukuiri, T.; Anniko, M.; Hirakawa, K. Expression of transient receptor potential channel vanilloid (TRPV) 1-4, melastin (TRPM) 5 and 8, and ankyrin (TRPA1) in the normal and methimazole-treated mouse olfactory epithelium. Acta Otolaryngol. 2010, 130, 1278-1286.
    • (2010) Acta Otolaryngol , vol.130 , pp. 1278-1286
    • Nakashimo, Y.1    Takumida, M.2    Fukuiri, T.3    Anniko, M.4    Hirakawa, K.5
  • 36
    • 34250857978 scopus 로고    scopus 로고
    • Differential expression of the capsaicin receptor trpv1 and related novel receptors trpv3 trpv4 and trpm8 in normal human tissues and changes in traumatic and diabetic neuropathy
    • Facer, P.; Casula, M.A.; Smith, G.D.; Benham, C.D.; Chessell, I.P.; Bountra, C.; Sinisi, M.; Birch, R.; Anand, P. Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy. Neurology, 2007, 7, 1-12.
    • (2007) Neurology , vol.7 , pp. 1-12
    • Facer, P.1    Casula, M.A.2    Smith, G.D.3    Benham, C.D.4    Chessell, I.P.5    Bountra, C.6    Sinisi, M.7    Birch, R.8    Anand, P.9
  • 38
    • 79955918810 scopus 로고    scopus 로고
    • Pharmacogenetics of new analgesics
    • Lötsch, J.; Geisslinger, G. Pharmacogenetics of new analgesics. Br. J. Pharmacol., 2011, 163, 447-460.
    • (2011) Br. J. Pharmacol , vol.163 , pp. 447-460
    • Lötsch, J.1    Geisslinger, G.2
  • 39
    • 84856017761 scopus 로고    scopus 로고
    • Research yields new insights into mechanisms and treatment of pain
    • Friedrich, M.J. Research yields new insights into mechanisms and treatment of pain. JAMA, 2012, 307, 239-241.
    • (2012) JAMA , vol.307 , pp. 239-241
    • Friedrich, M.J.1
  • 40
    • 28844471303 scopus 로고    scopus 로고
    • Distinct expression of trpm8, trpa1, and trpv1 mrnas in rat primary afferent neurons with adelta/c-fibers and colocalization with trk receptors
    • Kobayashi, K.; Fukuoka, T.; Obata, K.; Yamanaka, H.; Dai, Y.; Tokunaga, A.; Noguchi, K. Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with Adelta/C-fibers and colocalization with trk receptors. J. Comp. Neurol., 2005, 493, 596-606.
    • (2005) J. Comp. Neurol , vol.493 , pp. 596-606
    • Kobayashi, K.1    Fukuoka, T.2    Obata, K.3    Yamanaka, H.4    Dai, Y.5    Tokunaga, A.6    Noguchi, K.7
  • 41
    • 69249213916 scopus 로고    scopus 로고
    • Is thermal nociception only sensed by the capsaicin receptor, trpv1?
    • Hiura, A. Is thermal nociception only sensed by the capsaicin receptor, TRPV1? Anat . Sci. Int., 2009, 84, 122-128.
    • (2009) Anat . Sci. Int , vol.84 , pp. 122-128
    • Hiura, A.1
  • 42
    • 67049154139 scopus 로고    scopus 로고
    • Intragastric administration of trpv1, trpv3, trpm8, and trpa1 agonists modulates autonomic thermoregulation in different manners in mice
    • Masamoto, Y.; Kawabata, F.; Fushiki, T. Intragastric administration of TRPV1, TRPV3, TRPM8, and TRPA1 agonists modulates autonomic thermoregulation in different manners in mice. Biosci. Biotechnol. Biochem., 2009, 73, 1021-1027.
    • (2009) Biosci. Biotechnol. Biochem , vol.73 , pp. 1021-1027
    • Masamoto, Y.1    Kawabata, F.2    Fushiki, T.3
  • 43
    • 33750358054 scopus 로고    scopus 로고
    • Trpv1: A therapeutic target for novel analgesic drugs?
    • Szallasi, A.; Cruz, F.; Geppetti, P. TRPV1: a therapeutic target for novel analgesic drugs? Trends Mol. Med., 2006, 12, 545-554.
    • (2006) Trends MoL. Med , vol.12 , pp. 545-554
    • Szallasi, A.1    Cruz, F.2    Geppetti, P.3
  • 44
    • 77951706386 scopus 로고    scopus 로고
    • Vanilloid and melastatin transient receptor potential channels in vascular smooth muscle
    • Earley, S. Vanilloid and melastatin transient receptor potential channels in vascular smooth muscle. Microcirculation, 2010, 17, 237-249.
    • (2010) Microcirculation , vol.17 , pp. 237-249
    • Earley, S.1
  • 45
    • 0038187752 scopus 로고    scopus 로고
    • Development of nociceptive synaptic inputs to the neonatal rat dorsal horn: Glutamate release by capsaicin and mentol
    • Baccei, M.L.; Bardoni, R.; Fitzgerald, M. Development of nociceptive synaptic inputs to the neonatal rat dorsal horn: glutamate release by capsaicin and mentol. J. Physiol., 2003, 549, 231-242.
    • (2003) J. Physiol , vol.549 , pp. 231-242
    • Baccei, M.L.1    Bardoni, R.2    Fitzgerald, M.3
  • 46
    • 18044389382 scopus 로고    scopus 로고
    • Contribution of natural products to the discovery of the transient receptor potential (trp) channels family and their functions
    • Calixto, J.B.; Kassuya, C.A.; Andre, E.; Ferreira. J. Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions. Pharmacol. Ther., 2005, 106, 179-208.
    • (2005) Pharmacol. Ther , vol.106 , pp. 179-208
    • Calixto, J.B.1    Kassuya, C.A.2    Andre, E.3    Ferreira, J.4
  • 50
    • 33644766044 scopus 로고    scopus 로고
    • Elevation of endocannabinoid levels in the ventrolateral periaqueducal gray through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type 1 receptors
    • Maione, S.; Bisogno, T.; De Novellis, V.; Palazzo, E.; Cristino, L.; Valenti, M.; Petrosino, S.; Guglielmotti, V.; Rossi, F.; Di Marzo, V. Elevation of endocannabinoid levels in the ventrolateral periaqueducal gray through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type 1 receptors. J. Pharmacol. Exp. Ther., 2006, 316, 969-982.
    • (2006) J. Pharmacol. Exp. Ther , vol.316 , pp. 969-982
    • Maione, S.1    Bisogno, T.2    De Novellis, V.3    Palazzo, E.4    Cristino, L.5    Valenti, M.6    Petrosino, S.7    Guglielmotti, V.8    Rossi, F.9    Di Marzo, V.10
  • 51
    • 33747314445 scopus 로고    scopus 로고
    • Role of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes
    • Manzanares, J.; Julian, M.D.; Carrascosa, A. Role of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes. Curr. Neuropharmacol., 2006, 4, 239-257.
    • (2006) Curr. Neuropharmacol , vol.4 , pp. 239-257
    • Manzanares, J.1    Julian, M.D.2    Carrascosa, A.3
  • 54
    • 22944473968 scopus 로고    scopus 로고
    • Activation and activators of trpv1 and their pharmaceutical implication
    • Suh, Y.G.; Oh, U. Activation and activators of TRPV1 and their pharmaceutical implication. Curr. Pharm. Des., 2005, 11, 2687-2698.
    • (2005) Curr. Pharm. Des , vol.11 , pp. 2687-2698
    • Suh, Y.G.1    Oh, U.2
  • 56
    • 57249108274 scopus 로고    scopus 로고
    • The glutamatergic nature of trpv1-expressing neurons in the spinal dorsal horn
    • Zhou, H.; Chen, S.; Chen, H.; Pan, H. The glutamatergic nature of TRPV1-expressing neurons in the spinal dorsal horn. J. Neurochem., 2009, 108, 305-318.
    • (2009) J. Neurochem , vol.108 , pp. 305-318
    • Zhou, H.1    Chen, S.2    Chen, H.3    Pan, H.4
  • 57
    • 58149483491 scopus 로고    scopus 로고
    • Trpv1 antagonists: The challenges for therapeutic targeting
    • Khairatkar-Joshi, N.; Szallasi, A. TRPV1 antagonists: the challenges for therapeutic targeting. Trends Mol. Med., 2009, 15, 14-22.
    • (2009) Trends Mol. Med , vol.15 , pp. 14-22
    • Khairatkar-Joshi, N.1    Szallasi, A.2
  • 58
    • 79954616426 scopus 로고    scopus 로고
    • Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits trpv3 and trpa1 ion channels
    • Bang, S.; Yoo, S.; Yang, T.J.; Cho, H.; Hwang, S.W. Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels. Pain, 2011, 152, 1165-1164.
    • (2011) Pain , vol.152 , pp. 1165-1164
    • Bang, S.1    Yoo, S.2    Yang, T.J.3    Cho, H.4    Hwang, S.W.5
  • 60
    • 61549112170 scopus 로고    scopus 로고
    • Sensory attributes of complex tasting divalent salts are mediated by trpm5 and trpv1 channels
    • Riera, C.E.; Vogel, H.; Simon, S.A.; Damak, S.; le Coutre, J. Sensory attributes of complex tasting divalent salts are mediated by TRPM5 and TRPV1 channels. J. Neurosci., 2009, 29, 2654-2662.
    • (2009) J. Neurosci , vol.29 , pp. 2654-2662
    • Riera, C.E.1    Vogel, H.2    Simon, S.A.3    Damak, S.4    Le Coutre, J.5
  • 62
    • 54049146846 scopus 로고    scopus 로고
    • Overexpression of artemin in the tongue increases expression of trpv1 and trpa1 in trigeminal afferents and causes oral sensitivity to capsaicin and mustard oil
    • Elitt, C.M.; Malin, S.A.; Koerber, H.R.; Davis, B.M.; Albers, K.M. Overexpression of artemin in the tongue increases expression of TRPV1 and TRPA1 in trigeminal afferents and causes oral sensitivity to capsaicin and mustard oil. Brain Res., 2008, 1230, 80-90.
    • (2008) Brain Res , vol.1230 , pp. 80-90
    • Elitt, C.M.1    Malin, S.A.2    Koerber, H.R.3    Davis, B.M.4    Albers, K.M.5
  • 65
    • 76949100698 scopus 로고    scopus 로고
    • The roles of ipla2, trpm8 and trpa1 in chemically induced cold hypersensitivity
    • Gentry, C.; Stoakley, N.; Andersson, D.A.; Bevan, S. The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity. Mol. Pain, 2010, 6, 4.
    • (2010) Mol. Pain , vol.6 , pp. 4
    • Gentry, C.1    Stoakley, N.2    Andersson, D.A.3    Bevan, S.4
  • 66
    • 48949120632 scopus 로고    scopus 로고
    • Trpa1: Irritant detector of the airways
    • Gerhold, K.A.; Bautista, D.M. TRPA1: irritant detector of the airways. J. Physiol., 2008, 586, 3303.
    • (2008) J. Physiol , vol.586 , pp. 3303
    • Gerhold, K.A.1    Bautista, D.M.2
  • 67
    • 56249135269 scopus 로고    scopus 로고
    • Caffeine activates mouse trpa1 channels but suppresses human trpa1 channels
    • Nagatomo, K.; Kubo, Y. Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels. Proc. Natl. Acad. Sci. USA, 2008, 105, 17373-17378.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 17373-17378
    • Nagatomo, K.1    Kubo, Y.2
  • 68
    • 34249693460 scopus 로고    scopus 로고
    • Increased trpa1 trpm8, and trpv2 expression in dorsal root ganglia by nerve injury
    • Frederick, J.; Buck, M.E.; Matson, D.J.; Cortright, D.N. Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury. Biochem. Biophys. Res. Commun., 2007, 358, 1058-1064.
    • (2007) Biochem. Biophys. Res. Commun , vol.358 , pp. 1058-1064
    • Frederick, J.1    Buck, M.E.2    Matson, D.J.3    Cortright, D.N.4
  • 69
    • 33748418461 scopus 로고    scopus 로고
    • Thermosensitive trp ion channels mediate cytosolic calcium response in human synoviocytes
    • Kochukov, M.Y.; McNearney, T.A.; Fu, Y.; Westlund, K.N. Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes. Am. J. Physiol. Cell Physiol., 2006, 291, C424-432.
    • (2006) Am. J. Physiol. Cell Physiol , vol.291
    • Kochukov, M.Y.1    McNearney, T.A.2    Fu, Y.3    Westlund, K.N.4
  • 72
    • 77949537828 scopus 로고    scopus 로고
    • Comparative effects of heterologous trpv1 and trpm8 expression in rat hippocampal neurons
    • Crawford, D.C.; Moulder, K.L.; Gereau, R.W.; Story, G.M.; Mennerick, S. Comparative effects of heterologous TRPV1 and TRPM8 expression in rat hippocampal neurons. PLoS One, 2009, 4, e8166.
    • (2009) PLoS One , vol.4
    • Crawford, D.C.1    Moulder, K.L.2    Gereau, R.W.3    Story, G.M.4    Mennerick, S.5
  • 74
    • 77950927723 scopus 로고    scopus 로고
    • Activation of trpa1 channels by fenamate nonsteroidal anti-inflammatory drugs
    • Hu, H.; Tian, J.; Zhu, Y.; Wang, C.; Xiao, R.; Herz, J.M.; Wood, J.D.; Zhu, M.X. Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs. Pflugers Arch., 2010, 459, 579-592.
    • (2010) Pflugers Arch , vol.459 , pp. 579-592
    • Hu, H.1    Tian, J.2    Zhu, Y.3    Wang, C.4    Xiao, R.5    Herz, J.M.6    Wood, J.D.7    Zhu, M.X.8
  • 75
    • 48949120476 scopus 로고    scopus 로고
    • Relative contributions of trpa1 and trpv1 channels in the activation of vagal bronchopulmonary c-fibres by the endogenous autacoid 4-oxononenal
    • Taylor-Clark, T.E.; McAlexander, M.A.; Nassenstein, C.; Sheardown, S.A.; Wilson, S.; Thornton, J.; Carr, M.J.; Undem, B.J. Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal. J. Physiol., 2008, 586, 3447-3459.
    • (2008) J. Physiol , vol.586 , pp. 3447-3459
    • Taylor-Clark, T.E.1    McAlexander, M.A.2    Nassenstein, C.3    Sheardown, S.A.4    Wilson, S.5    Thornton, J.6    Carr, M.J.7    Undem, B.J.8
  • 76
    • 77951173732 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice
    • Ta, L.E.; Bieber, A.J.; Carlton, S.M.; Loprinzi, C.L.; Low, P.A.; Windebank, A.J. Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice. Mol. Pain, 2010, 6, 15.
    • (2010) Mol. Pain , vol.6 , pp. 15
    • Ta, L.E.1    Bieber, A.J.2    Carlton, S.M.3    Loprinzi, C.L.4    Low, P.A.5    Windebank, A.J.6
  • 78
    • 0035798217 scopus 로고    scopus 로고
    • Involvement of vanilloid receptor vr1 and prostanoids in the acid-induced writhing responses of mice
    • Ikeda, Y.; Ueno, A.; Naraba, H.; Oh-ishi, S. Involvement of vanilloid receptor VR1 and prostanoids in the acid-induced writhing responses of mice. Life Sci., 2001, 69, 2911-2919.
    • (2001) Life Sci , vol.69 , pp. 2911-2919
    • Ikeda, Y.1    Ueno, A.2    Naraba, H.3    Oh-ishi, S.4
  • 79
    • 0035986316 scopus 로고    scopus 로고
    • Capsazepine inhibits thermal hyperalgesia but not nociception triggered by protease-activated receptors-2 in rats
    • Kawao, N.; Shimada, C.; Itoh, H.; Kuroda, R.; Kawabata, A. Capsazepine inhibits thermal hyperalgesia but not nociception triggered by protease-activated receptors-2 in rats. Jpn. J. Pharmacol., 2002, 89, 184-187.
    • (2002) Jpn. J. Pharmacol , vol.89 , pp. 184-187
    • Kawao, N.1    Shimada, C.2    Itoh, H.3    Kuroda, R.4    Kawabata, A.5
  • 80
    • 65649106202 scopus 로고    scopus 로고
    • Functional interaction between trpv1 and mu-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia
    • Maione, S.; Starowicz, K,; Cristino, L.; Guida, F.; Palazzo, E.; Luongo, L.; Rossi, F.; Marabese, I.; de Novellis, V.; Di Marzo, V. Functional interaction between TRPV1 and mu-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia. J. Neurophysiol., 2009, 101, 2411-2422.
    • (2009) J. Neurophysiol , vol.101 , pp. 2411-2422
    • Maione, S.1    Starowicz, K.2    Cristino, L.3    Guida, F.4    Palazzo, E.5    Luongo, L.6    Rossi, F.7    Marabese, I.8    De Novellis, V.9    Di Marzo, V.10
  • 81
    • 31144471480 scopus 로고    scopus 로고
    • Analysis of the antinociceptive effect of the flavonoid myricitrin: Evidence for a role of the l-arginine-nitric oxide and protein kinase c pathways
    • Meotti, F.C.; Luiz, A.P.; Pizzolatti, M.G.; Kassuya, C.A.; Calixto, J.B.; Santos, A.R. Analysis of the antinociceptive effect of the flavonoid myricitrin: Evidence for a role of the L-arginine-nitric oxide and protein kinase C pathways. J. Pharmacol. Exp. Ther., 2006, 316, 789-796.
    • (2006) J. Pharmacol. Exp. Ther , vol.316 , pp. 789-796
    • Meotti, F.C.1    Luiz, A.P.2    Pizzolatti, M.G.3    Kassuya, C.A.4    Calixto, J.B.5    Santos, A.R.6
  • 82
    • 33750399000 scopus 로고    scopus 로고
    • Potentiation of transient potential v1 functions by the activation of metabotropic 5-ht receptors in rat primary sensory neurons
    • Ohta, T.; Ikemi, Y.; Murakami, M.; Imagawa, T.; Otsuguro, K.; Ito, S. Potentiation of transient potential V1 functions by the activation of metabotropic 5-HT receptors in rat primary sensory neurons. J. Physiol., 2006, 576, 809-822.
    • (2006) J. Physiol , vol.576 , pp. 809-822
    • Ohta, T.1    Ikemi, Y.2    Murakami, M.3    Imagawa, T.4    Otsuguro, K.5    Ito, S.6
  • 83
    • 44049107494 scopus 로고    scopus 로고
    • Novel gating and sensitizing mechanism of capsaicin receptor (trpv1): Tonic inhibitory regulation of extracellular sodium through the external protonation sites on trpv1
    • Ohta, T.; Imagawa, T.; Ito, S. Novel gating and sensitizing mechanism of capsaicin receptor (TRPV1): tonic inhibitory regulation of extracellular sodium through the external protonation sites on TRPV1. J. Biol. Chem., 2008, 283, 9377-9387.
    • (2008) J. Biol. Chem , vol.283 , pp. 9377-9387
    • Ohta, T.1    Imagawa, T.2    Ito, S.3
  • 85
    • 0035173995 scopus 로고    scopus 로고
    • Iodo-resiniferatoxin a new potent vanilloid receptor antagonist
    • Wahl, P.; Foged, C.; Tillin, S.; Thomasen, C. Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist. Mol. Pharmacol., 2001, 59, 9-15.
    • (2001) Mol. Pharmacol , vol.59 , pp. 9-15
    • Wahl, P.1    Foged, C.2    Tillin, S.3    Thomasen, C.4
  • 86
    • 42249088582 scopus 로고    scopus 로고
    • Role of trpv1 receptors in descending modulation of pain
    • Palazzo, E.; Rossi, F.; Maione, S. Role of TRPV1 receptors in descending modulation of pain. Mol. Cell. Endocrinol., 2008, 286, S79-S83.
    • (2008) Mol. Cell. Endocrinol , vol.286
    • Palazzo, E.1    Rossi, F.2    Maione, S.3
  • 87
    • 58149107126 scopus 로고    scopus 로고
    • Clinical development of trpv1 antagonists: Targeting a pivotal point in the pain pathway
    • Gunthorpe, M.J.; Chizh, B.A. Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway. Drug Discov. Today, 2009, 14, 56-67.
    • (2009) Drug Discov. Today , vol.14 , pp. 56-67
    • Gunthorpe, M.J.1    Chizh, B.A.2
  • 90
    • 67349195455 scopus 로고    scopus 로고
    • Differential effects of trpv channel block on polymodal activation of rat cutaneous nociceptors in vitro
    • St Pierre, M.; Reeh, P.W.; Zimmermann, K. Differential effects of TRPV channel block on polymodal activation of rat cutaneous nociceptors in vitro. Exp. Brain. Res., 2009, 196, 31-44.
    • (2009) Exp. Brain. Res , vol.196 , pp. 31-44
    • St Pierre, M.1    Reeh, P.W.2    Zimmermann, K.3
  • 91
    • 0035261565 scopus 로고    scopus 로고
    • Molecular physiology of proton transduction in nociceptors
    • Reed, P.W.; Kress, M. Molecular physiology of proton transduction in nociceptors. Curr. Opin. Pharmacol., 2001, 1, 45-51.
    • (2001) Curr. Opin. Pharmacol , vol.1 , pp. 45-51
    • Reed, P.W.1    Kress, M.2
  • 92
    • 58449090339 scopus 로고    scopus 로고
    • Capsaicin receptor antagonists: A promising new addition to the pain clinic
    • Lambert, D.G. Capsaicin receptor antagonists: a promising new addition to the pain clinic. Br. J. Anaesth., 2009, 102, 153-155.
    • (2009) Br. J. Anaesth , vol.102 , pp. 153-155
    • Lambert, D.G.1
  • 95
    • 63649126112 scopus 로고    scopus 로고
    • Therapeutic potential of vanilloid receptor trpv1 agonists and antagonists as analgesics: Recent advances and setbacks
    • Wong, G.Y.; Gavva, N.R. Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks. Brain Res. Rev., 2009, 60, 267-277.
    • (2009) Brain Res. Rev , vol.60 , pp. 267-277
    • Wong, G.Y.1    Gavva, N.R.2
  • 98
    • 84877961328 scopus 로고    scopus 로고
    • http://clinicaltrials.gov/ct2/show/NCT01416116;m
  • 99
    • 55549129906 scopus 로고    scopus 로고
    • Ngx-4010 c116 study group.ngx-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: A randomised, double-blind study
    • Backonja, M.; Wallace, M.S.; Blonsky, E.R.; Cutler, B.J.; Malan, P.Jr.; Rauck, R.; Tobias, J.; NGX-4010 C116 Study Group.NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study. Lancet Neurol., 2008, 7, 1106-1112.
    • (2008) Lancet Neurol , vol.7 , pp. 1106-1112
    • Backonja, M.1    Wallace, M.S.2    Blonsky, E.R.3    Cutler, B.J.4    Malan, P.Jr.5    Rauck, R.6    Tobias, J.7
  • 100
    • 78650397133 scopus 로고    scopus 로고
    • Qutenza®: A capsaicin 8% patch for the management of postherpetic neuralgia
    • Wallace, M.; Pappagallo, M. Qutenza®: a capsaicin 8% patch for the management of postherpetic neuralgia. Expert Rev. Neurother., 2011, 11, 15-27.
    • (2011) Expert Rev. Neurother , vol.11 , pp. 15-27
    • Wallace, M.1    Pappagallo, M.2
  • 101
    • 77953090128 scopus 로고    scopus 로고
    • Ngx-4010 c118 study group. Longterm safety of ngx-4010, a high-concentration capsaicin patch, in patients with peripheral neuropathic pain
    • Simpson, D.M.; Gazda, S.; Brown, S.; Webster, L.R.; Lu, S.P.; Tobias, J.K.; Vanhove, G.F.; NGX-4010 C118 Study Group. Longterm safety of NGX-4010, a high-concentration capsaicin patch, in patients with peripheral neuropathic pain. J. Pain Symptom. Manage., 2010, 39, 1053-1064.
    • (2010) J. Pain Symptom. Manage , vol.39 , pp. 1053-1064
    • Simpson, D.M.1    Gazda, S.2    Brown, S.3    Webster, L.R.4    Lu, S.P.5    Tobias, J.K.6    Vanhove, G.F.7
  • 102
    • 84855769234 scopus 로고    scopus 로고
    • Analgesic anticonvulsant and antioxidant activities of 3-[4-(3-trifluoromethyl-phenyl) piperazin-1-yl]-dihydrofuran-2-one dihydrochloride in mice
    • Salat, K.; Moniczewski, A.; Salat, R.; Janaszek, M.; Filipek, B.; Malawska, B.; Wieckowski, K. Analgesic, anticonvulsant and antioxidant activities of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one dihydrochloride in mice. Pharmacol. Biochem. Behav., 2012, 101, 138-147.
    • (2012) Pharmacol. Biochem. Behav , vol.101 , pp. 138-147
    • Salat, K.1    Moniczewski, A.2    Salat, R.3    Janaszek, M.4    Filipek, B.5    Malawska, B.6    Wieckowski, K.7
  • 103
    • 84864120610 scopus 로고    scopus 로고
    • Pharmacological characterization of (3s)-3-(hydroxymethyl)-4-(5- methylpyridin-2-yl) n-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]-3,4-dihydro-2h- benzo[b][1, 4]oxazine-8 carboxamide (jts-653) a novel transient receptor potential vanilloid 1 antagonist
    • Kitagawa, Y.; Miyai, A.; Usui, K.; Hamada, Y.; Deai, K.; Wada, M.; Koga, Y.; Sakata, M.; Hayashi, M.; Tominaga, M.; Matsushita, M. Pharmacological characterization of (3S)-3-(hydroxymethyl)-4-(5-methylpyridin-2-yl)-N-[6-(2,2,2- trifluoroethoxy)pyridin-3-yl]-3,4-dihydro-2H-benzo[b][1,4]oxazine-8 carboxamide (JTS-653), a novel Transient Receptor Potential Vanilloid 1 antagonist. J. Pharmacol. Exp. Ther., 2012
    • (2012) J Pharmacol Exp Ther
    • Kitagawa, Y.1    Miyai, A.2    Usui, K.3    Hamada, Y.4    Deai, K.5    Wada, M.6    Koga, Y.7    Sakata, M.8    Hayashi, M.9    Tominaga, M.10    Matsushita, M.11
  • 104
    • 54349127771 scopus 로고    scopus 로고
    • Body-temperature maintenance as the predominant function of the vanilloid receptor trpv1
    • Gavva, N.R. Body-temperature maintenance as the predominant function of the vanilloid receptor TRPV1. Trends Pharmacol. Sci., 2008, 29, 550-557.
    • (2008) Trends Pharmacol. Sci , vol.29 , pp. 550-557
    • Gavva, N.R.1
  • 105
    • 67949098853 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 1, vanilloid 2 and melastatin 8 immunoreactive nerve fibers in human skin from individuals with and without norrbottnian congenital insensitivity to pain
    • Axelsson, H.E.; Minde, J.K.; Sonesson, A.; Toolanen, G.; Högestätt, E.D.; Zygmunt, P.M. Transient receptor potential vanilloid 1, vanilloid 2 and melastatin 8 immunoreactive nerve fibers in human skin from individuals with and without Norrbottnian congenital insensitivity to pain. Neuroscience, 2009, 162, 1322-1332.
    • (2009) Neuroscience , vol.162 , pp. 1322-1332
    • Axelsson, H.E.1    Minde, J.K.2    Sonesson, A.3    Toolanen, G.4    Högestätt, E.D.5    Zygmunt, P.M.6
  • 106
    • 84877972224 scopus 로고    scopus 로고
    • www.glenmarkpharma.com
  • 107
    • 77956321337 scopus 로고    scopus 로고
    • Resolvin d1 attenuates activation of sensory transient receptor potential channels leading to multiple anti-nociception
    • Bang, S.; Yoo, S.; Yang, T.J.; Cho, H.; Kim, Y.G.; Hwang, S.W. Resolvin D1 attenuates activation of sensory transient receptor potential channels leading to multiple anti-nociception. Br. J. Pharmacol., 2010, 161, 707-720.
    • (2010) Br. J. Pharmacol , vol.161 , pp. 707-720
    • Bang, S.1    Yoo, S.2    Yang, T.J.3    Cho, H.4    Kim, Y.G.5    Hwang, S.W.6
  • 109
    • 64849093208 scopus 로고    scopus 로고
    • Trpa1-mediated responses in trigeminal sensory neurons: Interaction between trpa1 and trpv1
    • Salas, M.M.; Hargreaves, K.M.; Akopian, A.N. TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1. Eur. J. Neurosci., 2009, 29, 1568-1578.
    • (2009) Eur. J. Neurosci , vol.29 , pp. 1568-1578
    • Salas, M.M.1    Hargreaves, K.M.2    Akopian, A.N.3
  • 110
    • 77952650740 scopus 로고    scopus 로고
    • Dynamic changes in the trpa1 selectivity filter lead to progressive but reversible pore dilation
    • Banke, T.G.; Chaplan, S.R.; Wickenden, A.D. Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation. Am. J. Physiol. Cell. Physiol., 2010, 298, C1457-1468.
    • (2010) Am. J. Physiol. Cell. Physiol , vol.298
    • Banke, T.G.1    Chaplan, S.R.2    Wickenden, A.D.3
  • 111
    • 34547844249 scopus 로고    scopus 로고
    • Transient receptor potential trpa1 channel desensitization in sensory neurons is agonist dependent and regulated by trpv1-directed internalization
    • Akopian, A.N.; Ruparel, N.B.; Jeske, N.A.; Hargreaves, K.M. Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-directed internalization. J. Physiol., 2007, 583, 175-193.
    • (2007) J. Physiol , vol.583 , pp. 175-193
    • Akopian, A.N.1    Ruparel, N.B.2    Jeske, N.A.3    Hargreaves, K.M.4
  • 112
    • 77952051865 scopus 로고    scopus 로고
    • Contribution of trpv1-trpa1 interaction to the single channel properties of the trpa1 channel
    • Staruschenko, A.; Jeske, N.A.; Akopian, A.N. Contribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel. J. Biol. Chem., 2010, 285, 15167-1577.
    • (2010) J. Biol. Chem , vol.285 , pp. 15167-1577
    • Staruschenko, A.1    Jeske, N.A.2    Akopian, A.N.3
  • 113
    • 78650177442 scopus 로고    scopus 로고
    • Transient receptor potential v1 regulates activation and modulation of transient receptor potential a1 by ca2+
    • Patil, M.J.; Jeske, N.A.; Akopian, A.N. Transient receptor potential V1 regulates activation and modulation of transient receptor potential A1 by Ca2+. Neuroscience, 2010, 171, 1109-1119.
    • (2010) Neuroscience , vol.171 , pp. 1109-1119
    • Patil, M.J.1    Jeske, N.A.2    Akopian, A.N.3
  • 115
    • 77955304238 scopus 로고    scopus 로고
    • Trpm8, but not trpa1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo. Pain, 2010, 150, 340-350
    • No 11 Saat et al
    • Knowlton, W.M.; Bifolck-Fisher, A.; Bautista, D.M.; McKemy, D.D. TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo. Pain, 2010, 150, 340-350. 1436 Current Medicinal Chemistry, 2013, Vol. 20, No. 11 Sa;at et al.
    • (2013) 1436 Current Medicinal Chemistry , vol.20
    • Knowlton, W.M.1    Bifolck-Fisher, A.2    Bautista, D.M.3    McKemy, D.D.4
  • 116
    • 65449169599 scopus 로고    scopus 로고
    • High concentrations of morphine sensitize and activate mouse dorsal root ganglia via trpv1 and trpa1 receptors
    • Forster, A.B.;Reeh, P.W.; Messlinger, K.; Fischer, M.J. High concentrations of morphine sensitize and activate mouse dorsal root ganglia via TRPV1 and TRPA1 receptors. Mol. Pain, 2009, 5, 17.
    • (2009) Mol. Pain , vol.5 , pp. 17
    • Forster, A.B.1    Reeh, P.W.2    Messlinger, K.3    Fischer, M.J.4
  • 118
    • 80053596592 scopus 로고    scopus 로고
    • Pharmacological blockade of trpm8 ion channels alters cold and cold pain responses in mice
    • Knowlton, W.M.; Daniels, R.L.; Palkar, R.; McCoy, D.D.; McKemy, D.D. Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice. PLoS One, 2011, 6, e25894.
    • (2011) PLoS One , vol.6
    • Knowlton, W.M.1    Daniels, R.L.2    Palkar, R.3    McCoy, D.D.4    McKemy, D.D.5
  • 119
    • 52049107394 scopus 로고    scopus 로고
    • Trps in our senses
    • doi 101016/jcub200807063
    • Damann, N.; Voets, T.; Nilius, B. TRPs in our senses. Curr Biol., 2008, 18(18), R880-889. doi: 10.1016/j.cub.2008.07.063.
    • (2008) Curr Biol , vol.18 , Issue.18
    • Damann, N.1    Voets, T.2    Nilius, B.3
  • 120
    • 77957162897 scopus 로고    scopus 로고
    • Trpm1: A vertebrate trp channel responsible for retinal on bipolar function
    • doi: 10.1016/j.ceca.2010.08.004
    • Koike, C.; Numata, T.; Ueda, H.; Mori, Y.; Furukawa, T. TRPM1: a vertebrate TRP channel responsible for retinal ON bipolar function. Cell Calcium, 2010, 48(2-3), 95-101. doi: 10.1016/j.ceca.2010.08.004.
    • (2010) Cell Calcium , vol.48 , Issue.2-3 , pp. 95-101
    • Koike, C.1    Numata, T.2    Ueda, H.3    Mori, Y.4    Furukawa, T.5
  • 121
    • 79955633340 scopus 로고    scopus 로고
    • The history of trp channels a commentary and reflection
    • doi: 10.1007/s00424-010-0920-3
    • Montell, C. The history of TRP channels, a commentary and reflection. Pflugers Arch., 2011, 461(5), 499-506. doi: 10.1007/s00424-010-0920-3.
    • (2011) Pflugers Arch , vol.461 , Issue.5 , pp. 499-506
    • Montell, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.