메뉴 건너뛰기




Volumn 196, Issue 1, 2009, Pages 31-44

Differential effects of TRPV channel block on polymodal activation of rat cutaneous nociceptors in vitro

Author keywords

Capsaicin receptor; Desensitization; Heat transduction; Polymodal nociceptor; Protons; TRPV channels

Indexed keywords

CAPSAICIN; PROTON; RUTHENIUM RED; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 2; VANILLOID RECEPTOR 3; VANILLOID RECEPTOR 4;

EID: 67349195455     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-009-1808-3     Document Type: Review
Times cited : (42)

References (79)
  • 1
    • 0025778737 scopus 로고
    • Ruthenium red as a capsaicin antagonist
    • R Amann CA Maggi 1991 Ruthenium red as a capsaicin antagonist Life Sci 49 849 856
    • (1991) Life Sci , vol.49 , pp. 849-856
    • Amann, R.1    Maggi, C.A.2
  • 2
    • 0025166553 scopus 로고
    • Activation of primary afferent neurons by thermal stimulation. Influence of ruthenium red
    • R Amann J Donnerer F Lembeck 1990 Activation of primary afferent neurons by thermal stimulation. Influence of ruthenium red Naunyn Schmiedebergs Arch Pharmacol 341 108 113 (Pubitemid 20062203)
    • (1990) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.341 , Issue.1-2 , pp. 108-113
    • Amann, R.1    Donnerer, J.2    Lembeck, F.3
  • 3
    • 0037074097 scopus 로고    scopus 로고
    • Cooling inhibits capsaicin-induced currents in cultured rat dorsal root ganglion neurones
    • DOI 10.1016/S0304-3940(01)02443-0, PII S0304394001024430
    • A Babes B Amuzescu U Krause A Scholz ML Flonta G Reid 2002 Cooling inhibits capsaicin-induced currents in cultured rat dorsal root ganglion neurones Neurosci Lett 317 131 134 (Pubitemid 34033729)
    • (2002) Neuroscience Letters , vol.317 , Issue.3 , pp. 131-134
    • Babes, A.1    Amuzescu, B.2    Krause, U.3    Scholz, A.4    Flonta, M.-L.5    Reid, G.6
  • 4
    • 1642280233 scopus 로고    scopus 로고
    • Background potassium channel block and TRPV1 activation contribute to proton depolarization of sensory neurons from humans with neuropathic pain
    • DOI 10.1111/j.1460-9568.2004.03097.x
    • TK Baumann P Chaudhary ME Martenson 2004 Background potassium channel block and TRPV1 activation contribute to proton depolarization of sensory neurons from humans with neuropathic pain Eur J NeuroSci 19 1343 1351 (Pubitemid 38387211)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.5 , pp. 1343-1351
    • Baumann, T.K.1    Chaudhary, P.2    Martenson, M.E.3
  • 5
    • 0014609028 scopus 로고
    • Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli
    • P Bessou ER Perl 1969 Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli J Neurophysiol 32 1025 1043
    • (1969) J Neurophysiol , vol.32 , pp. 1025-1043
    • Bessou, P.1    Perl, E.R.2
  • 6
    • 0027988505 scopus 로고
    • Protons: Small stimulants of capsaicin-sensitive sensory nerves
    • DOI 10.1016/0166-2236(94)90149-X
    • S Bevan P Geppetti 1994 Protons: small stimulants of capsaicin-sensitive sensory nerves Trends Neurosci 17 509 512 (Pubitemid 24347911)
    • (1994) Trends in Neurosciences , vol.17 , Issue.12 , pp. 509-512
    • Bevan, S.1    Geppetti, P.2
  • 7
    • 0026100801 scopus 로고
    • Protons activate a cation conductance in a sub-population of rat dorsal root ganglion neurones
    • S Bevan J Yeats 1991 Protons activate a cation conductance in a sub-population of rat dorsal root ganglion neurones J Physiol 433 145 161
    • (1991) J Physiol , vol.433 , pp. 145-161
    • Bevan, S.1    Yeats, J.2
  • 9
    • 0025852442 scopus 로고
    • Ruthenium red decreases capsaicin and citric acid-induced cough in guinea pigs
    • DC Bolser SM Aziz RW Chapman 1991 Ruthenium red decreases capsaicin and citric acid-induced cough in guinea pigs Neurosci Lett 126 131 133
    • (1991) Neurosci Lett , vol.126 , pp. 131-133
    • Bolser, D.C.1    Aziz, S.M.2    Chapman, R.W.3
  • 10
    • 0014489934 scopus 로고
    • Synthetic interstitial fluid for isolated mammalian tissue
    • AH Bretag 1969 Synthetic interstitial fluid for isolated mammalian tissue Life Sci 8 319 329
    • (1969) Life Sci , vol.8 , pp. 319-329
    • Bretag, A.H.1
  • 11
    • 0030777012 scopus 로고    scopus 로고
    • The capsaicin receptor: A heat-activated ion channel in the pain pathway
    • DOI 10.1038/39807
    • MJ Caterina MA Schumacher M Tominaga TA Rosen JD Levine D Julius 1997 The capsaicin receptor: a heat-activated ion channel in the pain pathway Nature 389 816 824 (Pubitemid 27462969)
    • (1997) Nature , vol.389 , Issue.6653 , pp. 816-824
    • Caterina, M.J.1    Schumacher, M.A.2    Tominaga, M.3    Rosen, T.A.4    Levine, J.D.5    Julius, D.6
  • 12
    • 0033119629 scopus 로고    scopus 로고
    • A capsaicin-receptor homologue with a high threshold for noxious heat
    • DOI 10.1038/18906
    • MJ Caterina TA Rosen M Tominaga AJ Brake D Julius 1999 A capsaicin-receptor homologue with a high threshold for noxious heat Nature 398 436 441 (Pubitemid 29180377)
    • (1999) Nature , vol.398 , Issue.6726 , pp. 436-441
    • Caterina, M.J.1    Rosen, T.A.2    Tominaga, M.3    Brake, A.J.4    Julius, D.5
  • 17
    • 0037333470 scopus 로고    scopus 로고
    • Ruthenium red inhibits TASK-3 potassium channel by interconnecting glutamate 70 of the two subunits
    • DOI 10.1124/mol.63.3.646
    • G Czirjak P Enyedi 2003 Ruthenium red inhibits TASK-3 potassium channel by interconnecting glutamate 70 of the two subunits Mol Pharmacol 63 646 652 (Pubitemid 36297336)
    • (2003) Molecular Pharmacology , vol.63 , Issue.3 , pp. 646-652
    • Czirjak, G.1    Enyedi, P.2
  • 19
    • 0029965156 scopus 로고    scopus 로고
    • Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats
    • DOI 10.1007/s004240050074
    • RJ Docherty JC Yeats S Bevan HW Boddeke 1996 Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats Pflugers Arch 431 828 837 (Pubitemid 26134693)
    • (1996) Pflugers Archiv European Journal of Physiology , vol.431 , Issue.6 , pp. 828-837
    • Docherty, R.J.1    Yeats, J.C.2    Bevan, S.3    Boddeke, H.W.G.M.4
  • 20
    • 0018252937 scopus 로고
    • The effect of ruthenium red and its interaction with membrane-bound sialic acid on contraction threshold in frog skeletal muscle [proceedings]
    • M Dorrscheidt-Kafer K Grocki 1978 The effect of ruthenium red and its interaction with membrane-bound sialic acid on contraction threshold in frog skeletal muscle [proceedings] J Physiol 284 52
    • (1978) J Physiol , vol.284 , pp. 52
    • Dorrscheidt-Kafer, M.1    Grocki, K.2
  • 21
    • 0024598599 scopus 로고
    • Capsaicin desensitization of peripheral nociceptive fibres does not impair sensitivity to other noxious stimuli
    • DOI 10.1016/0304-3940(89)90263-2
    • A Dray J Bettaney P Forster 1989 Capsaicin desensitization of peripheral nociceptive fibres does not impair sensitivity to other noxious stimuli Neurosci Lett 99 50 54 (Pubitemid 19098436)
    • (1989) Neuroscience Letters , vol.99 , Issue.1-2 , pp. 50-54
    • Dray, A.1    Bettaney, J.2    Forster, P.3
  • 22
    • 0025191123 scopus 로고
    • Ruthenium red blocks the capsaicin-induced increase in intracellular calcium and activation of membrane currents in sensory neurones as well as the activation of peripheral nociceptors in vitro
    • A Dray CA Forbes GM Burgess 1990 Ruthenium red blocks the capsaicin-induced increase in intracellular calcium and activation of membrane currents in sensory neurones as well as the activation of peripheral nociceptors in vitro Neurosci Lett 110 52 59 (Pubitemid 20059552)
    • (1990) Neuroscience Letters , vol.110 , Issue.1-2 , pp. 52-59
    • Dray, A.1    Forbes, C.A.2    Burgess, G.M.3
  • 23
    • 0042819827 scopus 로고    scopus 로고
    • Proton-induced calcitonin gene-related peptide release from rat sciatic nerve axons, in vitro, involving TRPV1
    • DOI 10.1046/j.1460-9568.2003.02811.x
    • MJ Fischer PW Reeh SK Sauer 2003 Proton-induced calcitonin gene-related peptide release from rat sciatic nerve axons, in vitro, involving TRPV1 Eur J NeuroSci 18 803 810 (Pubitemid 37059690)
    • (2003) European Journal of Neuroscience , vol.18 , Issue.4 , pp. 803-810
    • Fischer, M.J.M.1    Reeh, P.W.2    Sauer, S.K.3
  • 24
    • 0019970927 scopus 로고
    • The time course and specificity of the changes in the behavioral and dorsal horn cell responses to noxious stimuli following peripheral nerve capsaicin treatment in the rat
    • DOI 10.1016/0306-4522(82)90119-1
    • M Fitzgerald CJ Woolf 1982 The time course and specificity of the changes in the behavioural and dorsal horn cell responses to noxious stimuli following peripheral nerve capsaicin treatment in the rat Neuroscience 7 2051 2056 (Pubitemid 12034572)
    • (1982) Neuroscience , vol.7 , Issue.9 , pp. 2051-2056
    • Fitzgerald, M.1    Woolf, C.J.2
  • 25
    • 0025134244 scopus 로고
    • Automatic classification and analysis of microneurographic spike data using a PC/AT
    • DOI 10.1016/0165-0270(90)90155-9
    • C Forster HO Handwerker 1990 Automatic classification and analysis of microneurographic spike data using a PC/AT J Neurosci Methods 31 109 118 (Pubitemid 20044166)
    • (1990) Journal of Neuroscience Methods , vol.31 , Issue.2 , pp. 109-118
    • Forster, C.1    Handwerker, H.O.2
  • 26
    • 0019471236 scopus 로고
    • The action of some chemical irritants on somatosensory receptors of the cat
    • DOI 10.1016/0028-3908(81)90203-3
    • RW Foster AG Ramage 1981 The action of some chemical irritants on somatosensory receptors of the cat Neuropharmacology 20 191 198 (Pubitemid 11138088)
    • (1981) Neuropharmacology , vol.20 , Issue.2 , pp. 191-198
    • Foster, R.W.1    Ramage, A.G.2
  • 28
    • 0025339632 scopus 로고
    • Neurochemical evidence for the activation of the 'efferent' function of capsaicin-sensitive nerves by lowering of the pH in the guinea-pig urinary bladder
    • DOI 10.1016/0304-3940(90)90435-C
    • P Geppetti M Tramontana R Patacchini E Del Bianco P Santicioli CA Maggi 1990 Neurochemical evidence for the activation of the 'efferent' function of capsaicin-sensitive nerves by lowering of the pH in the guinea-pig urinary bladder Neurosci Lett 114 101 106 (Pubitemid 20178274)
    • (1990) Neuroscience Letters , vol.114 , Issue.1 , pp. 101-106
    • Geppetti, P.1    Tramontana, M.2    Patacchini, R.3    Del Bianco, E.4    Santicioli, P.5    Maggi, C.A.6
  • 29
    • 0025964165 scopus 로고
    • Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: Mechanism of action and biological response
    • P Geppetti E Del Bianco R Patacchini P Santicioli CA Maggi M Tramontana 1991 Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: mechanism of action and biological response Neuroscience 41 295 301
    • (1991) Neuroscience , vol.41 , pp. 295-301
    • Geppetti, P.1    Del Bianco, E.2    Patacchini, R.3    Santicioli, P.4    Maggi, C.A.5    Tramontana, M.6
  • 30
    • 0032589344 scopus 로고    scopus 로고
    • 2+](i) mediate capsaicin- and proton-induced heat sensitization of rat primary nociceptive neurons
    • DOI 10.1046/j.1460-9568.1999.00734.x
    • S Guenther PW Reeh M Kress 1999 Rises in [Ca2 +]i mediate capsaicin- and proton-induced heat sensitization of rat primary nociceptive neurons Eur J NeuroSci 11 3143 3150 (Pubitemid 29431649)
    • (1999) European Journal of Neuroscience , vol.11 , Issue.9 , pp. 3143-3150
    • Guenther, S.1    Reeh, P.W.2    Kress, M.3
  • 32
    • 0021338284 scopus 로고
    • Neurotoxin induced nerve cell degeneration: Possible involvement of calcium
    • DOI 10.1016/0006-8993(84)90969-7
    • G Jancso S Karcsu E Kiraly A Szebeni L Toth E Bacsy F Joo A Parducz 1984 Neurotoxin induced nerve cell degeneration: possible involvement of calcium Brain Res 295 211 216 (Pubitemid 14161028)
    • (1984) Brain Research , vol.295 , Issue.2 , pp. 211-216
    • Jancso, G.1    Karcsu, S.2    Kiraly, E.3
  • 33
    • 0026440476 scopus 로고
    • Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P
    • W Kessler C Kirchhoff PW Reeh HO Handwerker 1992 Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P Exp Brain Res 91 467 476
    • (1992) Exp Brain Res , vol.91 , pp. 467-476
    • Kessler, W.1    Kirchhoff, C.2    Reeh, P.W.3    Handwerker, H.O.4
  • 34
    • 3242734911 scopus 로고    scopus 로고
    • Why cooling is beneficial: Non-linear temperature-dependency of stimulated iCGRP release from isolated rat skin
    • DOI 10.1016/j.pain.2004.03.033, PII S0304395904001757
    • TI Kichko PW Reeh 2004 Why cooling is beneficial: non-linear temperature-dependency of stimulated iCGRP release from isolated rat skin Pain 110 215 219 (Pubitemid 38953285)
    • (2004) Pain , vol.110 , Issue.1-2 , pp. 215-219
    • Kichko, T.I.1    Reeh, P.W.2
  • 35
    • 0034737472 scopus 로고    scopus 로고
    • + channel family
    • DOI 10.1074/jbc.275.13.9340
    • Y Kim H Bang D Kim 2000 TASK-3, a new member of the tandem pore K(+) channel family J Biol Chem 275 9340 9347 (Pubitemid 30185157)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.13 , pp. 9340-9347
    • Kim, Y.1    Bang, H.2    Kim, D.3
  • 36
    • 0026548426 scopus 로고
    • Excitation of cutaneous sensory nerve endings in the rat by 4-aminopyridine and tetraethylammonium
    • C Kirchhoff JD Leah S Jung PW Reeh 1992 Excitation of cutaneous sensory nerve endings in the rat by 4-aminopyridine and tetraethylammonium J Neurophysiol 67 125 131
    • (1992) J Neurophysiol , vol.67 , pp. 125-131
    • Kirchhoff, C.1    Leah, J.D.2    Jung, S.3    Reeh, P.W.4
  • 37
    • 0033397096 scopus 로고    scopus 로고
    • Inhibition of rapid heat responses in nociceptive primary sensory neurons of rats by vanilloid receptor antagonists
    • T Kirschstein W Greffrath D Busselberg RD Treede 1999 Inhibition of rapid heat responses in nociceptive primary sensory neurons of rats by vanilloid receptor antagonists J Neurophysiol 82 2853 2860 (Pubitemid 30017417)
    • (1999) Journal of Neurophysiology , vol.82 , Issue.6 , pp. 2853-2860
    • Kirschstein, T.1    Greffrath, W.2    Busselberg, D.3    Treede, R.-D.4
  • 38
    • 0023159104 scopus 로고
    • Proton-induced transformation of calcium channel in chick dorsal root ganglion cells
    • A Konnerth HD Lux M Morad 1987 Proton-induced transformation of calcium channel in chick dorsal root ganglion cells J Physiol 386 603 633 (Pubitemid 17059737)
    • (1987) Journal of Physiology , vol.386 , pp. 603-633
    • Konnerth, A.1    Lux, H.D.2    Morad, M.3
  • 39
    • 0030582980 scopus 로고    scopus 로고
    • Low pH facilitates capsaicin responses in isolated sensory neurons of the rat
    • DOI 10.1016/0304-3940(96)12691-4
    • M Kress S Fetzer PW Reeh L Vyklicky 1996 Low pH facilitates capsaicin responses in isolated sensory neurons of the rat Neurosci Lett 211 5 8 (Pubitemid 26228014)
    • (1996) Neuroscience Letters , vol.211 , Issue.1 , pp. 5-8
    • Kress, M.1    Fetzer, S.2    Reeh, P.W.3    Vyklicky, L.4
  • 40
    • 0019185036 scopus 로고
    • A receptor for protons in the nerve cell membrane
    • DOI 10.1016/0306-4522(80)90149-9
    • OA Krishtal VI Pidoplichko 1980 A receptor for protons in the nerve cell membrane Neuroscience 5 2325 2327 (Pubitemid 11200029)
    • (1980) Neuroscience , vol.5 , Issue.12 , pp. 2325-2327
    • Krishtal, O.A.1    Pidoplichko, V.I.2
  • 41
    • 0035310745 scopus 로고    scopus 로고
    • Sustained sensitization and recruitment of rat cutaneous nociceptors by bradykinin and a novel theory of its excitatory action
    • DOI 10.1111/j.1469-7793.2001.0229g.x
    • YF Liang B Haake PW Reeh 2001 Sustained sensitization and recruitment of rat cutaneous nociceptors by bradykinin and a novel theory of its excitatory action J Physiol 532 229 239 (Pubitemid 32303285)
    • (2001) Journal of Physiology , vol.532 , Issue.1 , pp. 229-239
    • Liang, Y.-F.1    Haake, B.2    Reeh, P.W.3
  • 42
    • 0018332967 scopus 로고
    • The heat sensitization of polymodal nociceptors in the rabbit and its independence of the local blood flow
    • B Lynn 1979 The heat sensitization of polymodal nociceptors in the rabbit and its independence of the local blood flow J Physiol 287 493 507 (Pubitemid 9116694)
    • (1979) Journal of Physiology , vol.287 , pp. 493-507
    • Lynn, B.1
  • 43
    • 0020052002 scopus 로고
    • Primary afferent units from the hairy skin of the rat hind limb
    • B Lynn SE Carpenter 1982 Primary afferent units from the hairy skin of the rat hind limb Brain Res 238 29 43
    • (1982) Brain Res , vol.238 , pp. 29-43
    • Lynn, B.1    Carpenter, S.E.2
  • 44
    • 0027730899 scopus 로고
    • Block by ruthenium red of the ryanodine-activated calcium release channel of skeletal muscle
    • DOI 10.1085/jgp.102.6.1031
    • J Ma 1993 Block by ruthenium red of the ryanodine-activated calcium release channel of skeletal muscle J Gen Physiol 102 1031 1056 (Pubitemid 24004319)
    • (1993) Journal of General Physiology , vol.102 , Issue.6 , pp. 1031-1056
    • Ma, J.1
  • 45
    • 0023914844 scopus 로고
    • Protective action of Ruthenium red toward capsaicin desensitization of sensory fibers
    • DOI 10.1016/0304-3940(88)90126-7
    • CA Maggi R Patacchini P Santicioli S Giuliani P Geppetti A Meli 1988 Protective action of ruthenium red toward capsaicin desensitization of sensory fibers Neurosci Lett 88 201 205 (Pubitemid 18128806)
    • (1988) Neuroscience Letters , vol.88 , Issue.2 , pp. 201-205
    • Maggi, C.A.1    Patacchini, R.2    Santicioli, P.3    Giuliani, S.4    Geppetti, P.5    Meli, A.6
  • 46
    • 0033788731 scopus 로고    scopus 로고
    • Low-threshold heat response antagonized by capsazepine in chick sensory neurons, which are capsaicin-insensitive
    • DOI 10.1046/j.1460-9568.2000.00275.x
    • A Marin-Burgin S Reppenhagen A Klusch JR Wendland M Petersen 2000 Low-threshold heat response antagonized by capsazepine in chick sensory neurons, which are capsaicin-insensitive Eur J NeuroSci 12 3560 3566 (Pubitemid 30796057)
    • (2000) European Journal of Neuroscience , vol.12 , Issue.10 , pp. 3560-3566
    • Marin-Burgin, A.1    Reppenhagen, S.2    Klusch, A.3    Wendland, J.R.4    Petersen, M.5
  • 47
    • 0023785945 scopus 로고
    • Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes
    • DOI 10.1111/j.1471-4159.1988.tb03085.x
    • L Massieu R Tapia 1988 Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes J Neurochem 51 1184 1189 (Pubitemid 18224816)
    • (1988) Journal of Neurochemistry , vol.51 , Issue.4 , pp. 1184-1189
    • Massieu, L.1    Tapia, R.2
  • 48
    • 0015235776 scopus 로고
    • Specific inhibition of mitochondrial Ca++ transport by ruthenium red
    • CL Moore 1971 Specific inhibition of mitochondrial Ca++ transport by ruthenium red Biochem Biophys Res Commun 42 298 305
    • (1971) Biochem Biophys Res Commun , vol.42 , pp. 298-305
    • Moore, C.L.1
  • 50
    • 0023757461 scopus 로고
    • 2 spinal cord of the rat
    • TJ Ness GF Gebhart 1988 Characterization of neurons responsive to noxious colorectal distension in the T13-L2 spinal cord of the rat J Neurophysiol 60 1419 1438 (Pubitemid 18259070)
    • (1988) Journal of Neurophysiology , vol.60 , Issue.4 , pp. 1419-1438
    • Ness, T.J.1    Gebhart, G.F.2
  • 52
    • 0018675560 scopus 로고
    • Depression of spontaneous and ionophore-induced transmitter release by ruthenium red at the neuromuscular junction
    • DOI 10.1016/0361-9230(79)90111-4
    • RJ Person JA Kuhn 1979 Depression of spontaneous and ionophore-induced transmitter release by ruthenium red at the neuromuscular junction Brain Res Bull 4 669 674 (Pubitemid 10246025)
    • (1979) Brain Research Bulletin , vol.4 , Issue.5 , pp. 669-674
    • Person, R.J.1    Kuhn, J.A.2
  • 53
    • 2442598415 scopus 로고    scopus 로고
    • Effects of TRPV1 receptor antagonists on stimulated iCGRP release from isolated skin of rats and TRPV1 mutant mice
    • DOI 10.1016/j.pain.2004.01.038, PII S030439590400079X
    • G Pethö I Izydorczyk PW Reeh 2004 Effects of TRPV1 receptor antagonists on stimulated iCGRP release from isolated skin of rats and TRPV1 mutant mice Pain 109 284 290 (Pubitemid 38638705)
    • (2004) Pain , vol.109 , Issue.3 , pp. 284-290
    • Petho, G.1    Izydorczyk, I.2    Reeh, P.W.3
  • 54
    • 0009832893 scopus 로고
    • Sensory receptors in a mammalian skin-nerve in vitro preparation
    • PW Reeh 1988 Sensory receptors in a mammalian skin-nerve in vitro preparation Prog Brain Res 74 271 276 (Pubitemid 18200006)
    • (1988) Progress in Brain Research , vol.74 , pp. 271-276
    • Reeh, P.W.1
  • 55
    • 0035910629 scopus 로고    scopus 로고
    • Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones
    • DOI 10.1016/S0304-3940(00)01694-3, PII S0304394000016943
    • G Reid M Flonta 2001 Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones Neurosci Lett 297 171 174 (Pubitemid 32011301)
    • (2001) Neuroscience Letters , vol.297 , Issue.3 , pp. 171-174
    • Reid, G.1    Flonta, M.-L.2
  • 56
    • 0035793024 scopus 로고    scopus 로고
    • Comparison of intracellular calcium signals evoked by heat and capsaicin in cultured rat dorsal root ganglion neurons and in a cell line expressing the rat vanilloid receptor, VR1
    • DOI 10.1016/S0306-4522(00)00447-4, PII S0306452200004474
    • JR Savidge SP Ranasinghe HP Rang 2001 Comparison of intracellular calcium signals evoked by heat and capsaicin in cultured rat dorsal root ganglion neurons and in a cell line expressing the rat vanilloid receptor, VR1 Neuroscience 102 177 184 (Pubitemid 32171864)
    • (2001) Neuroscience , vol.102 , Issue.1 , pp. 177-184
    • Savidge, J.R.1    Ranasinghe, S.P.2    Rang, H.P.3
  • 57
    • 0027177163 scopus 로고
    • Sustained graded pain and hyperalgesia from harmless experimental tissue acidosis in human skin
    • KH Steen PW Reeh 1993 Sustained graded pain and hyperalgesia from harmless experimental tissue acidosis in human skin Neurosci Lett 154 113 116 (Pubitemid 23172334)
    • (1993) Neuroscience Letters , vol.154 , Issue.1-2 , pp. 113-116
    • Steen, K.H.1    Reeh, P.W.2
  • 58
    • 0026581550 scopus 로고
    • Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro
    • KH Steen PW Reeh F Anton HO Handwerker 1992 Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro J Neurosci 12 86 95
    • (1992) J Neurosci , vol.12 , pp. 86-95
    • Steen, K.H.1    Reeh, P.W.2    Anton, F.3    Handwerker, H.O.4
  • 59
    • 0032817158 scopus 로고    scopus 로고
    • +] and is increased under amiloride
    • DOI 10.1046/j.1460-9568.1999.00695.x
    • KH Steen H Wegner PW Reeh 1999 The pH response of rat cutaneous nociceptors correlates with extracellular [Na+] and is increased under amiloride Eur J NeuroSci 11 2783 2792 (Pubitemid 29364195)
    • (1999) European Journal of Neuroscience , vol.11 , Issue.8 , pp. 2783-2792
    • Steen, K.H.1    Wegner, H.2    Reeh, P.W.3
  • 60
    • 0019959497 scopus 로고
    • Slowing of sodium current inactivation by ruthenium red in snail neurons
    • DOI 10.1085/jgp.80.4.485
    • JR Stimers L Byerly 1982 Slowing of sodium current inactivation by ruthenium red in snail neurons J Gen Physiol 80 485 497 (Pubitemid 12037501)
    • (1982) Journal of General Physiology , vol.80 , Issue.4 , pp. 485-497
    • Stimers, J.R.1    Byerly, L.2
  • 61
    • 0030443812 scopus 로고    scopus 로고
    • Vanilloid receptors: New insights enhance potential as a therapeutic target
    • DOI 10.1016/S0304-3959(96)03202-2, PII S0304395996032022
    • A Szallasi PM Blumberg 1996 Vanilloid receptors: new insights enhance potential as a therapeutic target Pain 68 195 208 (Pubitemid 27025876)
    • (1996) Pain , vol.68 , Issue.2-3 , pp. 195-208
    • Szallasi, A.1    Blumberg, P.M.2
  • 62
    • 9644279616 scopus 로고    scopus 로고
    • Forty years in capsaicin research for sensory pharmacology and physiology
    • DOI 10.1016/j.npep.2004.07.005, PII S0143417904000757
    • J Szolcsanyi 2004 Forty years in capsaicin research for sensory pharmacology and physiology Neuropeptides 38 377 384 (Pubitemid 39572842)
    • (2004) Neuropeptides , vol.38 , Issue.6 , pp. 377-384
    • Szolcsanyi, J.1
  • 63
    • 0023924974 scopus 로고
    • Selective excitation by capsaicin of mechano-heat sensitive nociceptors in rat skin
    • DOI 10.1016/0006-8993(88)90885-2
    • J Szolcsanyi F Anton PW Reeh HO Handwerker 1988 Selective excitation by capsaicin of mechano-heat sensitive nociceptors in rat skin Brain Res 446 262 268 (Pubitemid 18101110)
    • (1988) Brain Research , vol.446 , Issue.2 , pp. 262-268
    • Szolcsanyi, J.1    Anton, F.2    Reeh, P.W.3    Handwerker, H.O.4
  • 64
    • 0025224503 scopus 로고
    • Resiniferatoxin: An ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons
    • J Szolcsanyi A Szallasi Z Szallasi F Joo PM Blumberg 1990 Resiniferatoxin: an ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons J Pharmacol Exp Ther 255 923 928
    • (1990) J Pharmacol Exp Ther , vol.255 , pp. 923-928
    • Szolcsanyi, J.1    Szallasi, A.2    Szallasi, Z.3    Joo, F.4    Blumberg, P.M.5
  • 66
    • 0017594495 scopus 로고
    • 3H]GABA in synaptosomal fractions
    • DOI 10.1016/0006-8993(77)90223-2
    • R Tapia G Meza-Ruiz 1977 Inhibition by ruthenium red of the calcium-dependent release of [3H]GABA in synaptosomal fractions Brain Res 126 160 166 (Pubitemid 8073266)
    • (1977) Brain Research , vol.126 , Issue.1 , pp. 160-166
    • Tapia, R.1    Meza Ruiz, G.2
  • 67
    • 0031022699 scopus 로고    scopus 로고
    • Ruthenium red as a tool to study calcium channels, neuronal death and the function of neural pathways
    • DOI 10.1016/S0197-0186(96)00056-3, PII S0197018696000563
    • R Tapia I Velasco 1997 Ruthenium red as a tool to study calcium channels, neuronal death and the function of neural pathways Neurochem Int 30 137 147 (Pubitemid 27029172)
    • (1997) Neurochemistry International , vol.30 , Issue.2 , pp. 137-147
    • Tapia, R.1    Velasco, I.2
  • 68
    • 0022226557 scopus 로고
    • Binding of lanthanum ions and ruthenium red to synaptosomes and its effects on neurotransmitter release
    • DOI 10.1111/j.1471-4159.1985.tb07213.x
    • R Tapia C Arias E Morales 1985 Binding of lanthanum ions and ruthenium red to synaptosomes and its effects on neurotransmitter release J Neurochem 45 1464 1470 (Pubitemid 16252584)
    • (1985) Journal of Neurochemistry , vol.45 , Issue.5 , pp. 1464-1470
    • Tapia, R.1    Arias, C.2    Morales, E.3
  • 71
    • 0033571905 scopus 로고    scopus 로고
    • Functional attributes discriminating mechano-insensitive and mechano- responsive C nociceptors in human skin
    • C Weidner M Schmelz R Schmidt B Hansson HO Handwerker HE Torebjork 1999 Functional attributes discriminating mechano-insensitive and mechano-responsive C nociceptors in human skin J Neurosci 19 10184 10190 (Pubitemid 30226690)
    • (1999) Journal of Neuroscience , vol.19 , Issue.22 , pp. 10184-10190
    • Weidner, C.1    Schmelz, M.2    Schmidt, R.3    Hansson, B.4    Handwerker, H.O.5    Torebjork, H.E.6
  • 72
    • 0022510418 scopus 로고
    • Evidence that ruthenium red disturbs the synaptic transmission in the rat hippocampal slices through interacting with sialic acid residues
    • DOI 10.1016/0006-8993(86)90292-1
    • A Wieraszko 1986 Evidence that ruthenium red disturbs the synaptic transmission in the rat hippocampal slices through interacting with sialic acid residues Brain Res 378 120 126 (Pubitemid 16055807)
    • (1986) Brain Research , vol.378 , Issue.1 , pp. 120-126
    • Wieraszko, A.1
  • 73
    • 0020395639 scopus 로고
    • The acute effects of capsaicin on rat primary afferents and spinal neurons
    • DOI 10.1016/0006-8993(82)90679-5
    • JT Williams W Zieglgansberger 1982 The acute effects of capsaicin on rat primary afferents and spinal neurons Brain Res 253 125 131 (Pubitemid 13212224)
    • (1982) Brain Research , vol.253 , Issue.1-2 , pp. 125-131
    • Williams, J.T.1    Zieglgansberger, W.2
  • 77
    • 26244447712 scopus 로고    scopus 로고
    • The TRPV1/2/3 activator 2-aminoethoxydiphenyl borate sensitizes native nociceptive neurons to heat in wildtype but not TRPV1 deficient mice
    • DOI 10.1016/j.neuroscience.2005.07.018, PII S0306452205007724
    • K Zimmermann A Leffler MM Fischer K Messlinger C Nau PW Reeh 2005 The TRPV1/2/3 activator 2-aminoethoxydiphenyl borate sensitizes native nociceptive neurons to heat in wildtype but not TRPV1 deficient mice Neuroscience 135 1277 1284 (Pubitemid 41416688)
    • (2005) Neuroscience , vol.135 , Issue.4 , pp. 1277-1284
    • Zimmermann, K.1    Leffler, A.2    Fischer, M.M.J.3    Messlinger, K.4    Nau, C.5    Reeh, P.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.