Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-directed internalization

Journal of Physiology

Volumn 583, Issue 1, 2007, Pages 175-193

  Akopian, Armen N ^a   Ruparel, Nikita B ^a   Jeske, Nathaniel A ^a   Hargreaves, Kenneth M ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYL ISOTHIOCYANATE; CALCINEURIN; CALCIUM ION; CAPSAICIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C; VANILLOID RECEPTOR 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOSENSOR; CONTROLLED STUDY; DESENSITIZATION; DRUG MECHANISM; ENZYME ACTIVATION; INTERNALIZATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; SENSORY NERVE CELL; SENSORY STIMULATION; SENSORY SYSTEM ELECTROPHYSIOLOGY; BIOTINYLATION; CALCIUM TRANSPORT; CHO CELL LINE; FEMALE; RECEPTOR DOWN REGULATION;

ANALGESICS, NON-NARCOTIC; ANIMALS; CALCINEURIN; CALCIUM; CALCIUM CHANNELS; CAPSAICIN; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; ION CHANNEL GATING; MICE; MICE, KNOCKOUT; MUSTARD PLANT; NEURONS, AFFERENT; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PLANT OILS; RATS; RATS, SPRAGUE-DAWLEY; TRPV CATION CHANNELS;

EID: 34547844249     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.133231     Document Type: Article

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