-
1
-
-
80051531363
-
Notch signaling: simplicity in design, versatility in function
-
Andersson E. Sandberg R. Lendahl U. (2011) Notch signaling: simplicity in design, versatility in function. Development 138: 3593–3612.
-
(2011)
Development
, vol.138
, pp. 3593-3612
-
-
Andersson, E.1
Sandberg, R.2
Lendahl, U.3
-
3
-
-
78549289477
-
Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes
-
Arnett K. Hass M. McArthur D. Ilagan M. Aster J. Kopan R. et al. (2010) Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes. Nat Struct Mol Biol 17: 1312–1317.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1312-1317
-
-
Arnett, K.1
Hass, M.2
McArthur, D.3
Ilagan, M.4
Aster, J.5
Kopan, R.6
-
4
-
-
77949395629
-
Characterization of Notch 1 antibodies that inhibit signaling of both normal and mutated Notch 1 receptors
-
Aste-Amezaga M. Zhang N. Lineberger J. Arnold B. Toner T. Gu M. et al. (2010) Characterization of Notch 1 antibodies that inhibit signaling of both normal and mutated Notch 1 receptors. PloS ONE 5 (2): e9094.
-
(2010)
PloS ONE
, vol.5
, Issue.2
, pp. e9094
-
-
Aste-Amezaga, M.1
Zhang, N.2
Lineberger, J.3
Arnold, B.4
Toner, T.5
Gu, M.6
-
5
-
-
84993799445
-
Aveo Pharmaceuticals, I. Notch Program
-
Available at
-
Aveo Pharmaceuticals, I. Notch Program. Available at: http://www.aveopharma.com/discovery_programs/notch_program/.
-
-
-
-
6
-
-
77955738891
-
Specificity of Notch pathway activation: twist controls the transcriptional output in adult muscle progenitors
-
Bernard F. Krejci A. Housden B. Adryan B. Bray S. (2010) Specificity of Notch pathway activation: twist controls the transcriptional output in adult muscle progenitors. Development 137: 2633–2642.
-
(2010)
Development
, vol.137
, pp. 2633-2642
-
-
Bernard, F.1
Krejci, A.2
Housden, B.3
Adryan, B.4
Bray, S.5
-
9
-
-
33747623018
-
Notch signalling: a simple pathway becomes complex
-
Bray S. (2006) Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 7: 678–689.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 678-689
-
-
Bray, S.1
-
11
-
-
84855501388
-
Notch 1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells
-
Cho S. Lu M. He X. Ee P. Bhat U. Schneider E. et al. (2011) Notch 1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells. Proc Natl Acad Sci U S A 108: 20778–20783.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 20778-20783
-
-
Cho, S.1
Lu, M.2
He, X.3
Ee, P.4
Bhat, U.5
Schneider, E.6
-
12
-
-
84860374357
-
Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma
-
Cook N. Frese K. Bapiro T. Jacobetz M. Gopinathan A. Miller J. et al. (2012) Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma. J Exp Med 209: 437–444.
-
(2012)
J Exp Med
, vol.209
, pp. 437-444
-
-
Cook, N.1
Frese, K.2
Bapiro, T.3
Jacobetz, M.4
Gopinathan, A.5
Miller, J.6
-
13
-
-
77954351997
-
Synthetic lethality through combined Notch-epidermal growth factor receptor pathway inhibition in basal-like breast cancer
-
Dong Y. Li A. Wang J. Weber J. Michel L. (2010) Synthetic lethality through combined Notch-epidermal growth factor receptor pathway inhibition in basal-like breast cancer. Cancer Res 70: 5465–5474.
-
(2010)
Cancer Res
, vol.70
, pp. 5465-5474
-
-
Dong, Y.1
Li, A.2
Wang, J.3
Weber, J.4
Michel, L.5
-
14
-
-
50849103301
-
Notch signaling regulates tumor angiogenesis by diverse mechanisms
-
Dufraine J. Funahashi Y. Kitajewski J. (2008) Notch signaling regulates tumor angiogenesis by diverse mechanisms. Oncogene 27: 5132–5137.
-
(2008)
Oncogene
, vol.27
, pp. 5132-5137
-
-
Dufraine, J.1
Funahashi, Y.2
Kitajewski, J.3
-
15
-
-
84993826394
-
Inhibition of Notch signaling for the treatment of human carcinomas
-
Proceedings of the American Assocication of Cancer Research Denver, CO
-
Epenetos A. Kosparou C. Stylianou S. (2009) Inhibition of Notch signaling for the treatment of human carcinomas. In: Proceedings of the American Assocication of Cancer Research, 18–22 April, Denver, CO.
-
(2009)
-
-
Epenetos, A.1
Kosparou, C.2
Stylianou, S.3
-
16
-
-
34247581697
-
Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways
-
Farnie G. Clarke R. Spence K. Pinnock N. Brennan K. Anderson N. et al. (2007) Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. J Natl Cancer Inst 99: 616–627.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 616-627
-
-
Farnie, G.1
Clarke, R.2
Spence, K.3
Pinnock, N.4
Brennan, K.5
Anderson, N.6
-
17
-
-
34547922380
-
Delta-Notch–and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors
-
Fischer A. Gessler M. (2007) Delta-Notch–and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res 35: 4583–4596.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 4583-4596
-
-
Fischer, A.1
Gessler, M.2
-
18
-
-
72449211223
-
The cytotoxicity of gamma-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by gamma-secretase inhibition
-
Han J. Ma I. Hendzel M. Allalunis-Turner J. (2009) The cytotoxicity of gamma-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by gamma-secretase inhibition. Breast Cancer Res 11 (4): R57.
-
(2009)
Breast Cancer Res
, vol.11
, Issue.4
, pp. R57
-
-
Han, J.1
Ma, I.2
Hendzel, M.3
Allalunis-Turner, J.4
-
19
-
-
76549084826
-
Regulation of breast cancer stem cell activity by signaling through the Notch 4 receptor
-
Harrison H. Farnie G. Howell S. Rock R. Stylianou S. Brennan K. et al. (2010) Regulation of breast cancer stem cell activity by signaling through the Notch 4 receptor. Cancer Res 70: 709–718.
-
(2010)
Cancer Res
, vol.70
, pp. 709-718
-
-
Harrison, H.1
Farnie, G.2
Howell, S.3
Rock, R.4
Stylianou, S.5
Brennan, K.6
-
21
-
-
79957443831
-
High tumor levels of IL 6 and IL 8 abrogate preclinical efficacy of the gamma-secretase inhibitor, RO4929097
-
He W. Luistro L. Carvajal D. Smith M. Nevins T. Yin X. et al. (2011) High tumor levels of IL 6 and IL 8 abrogate preclinical efficacy of the gamma-secretase inhibitor, RO4929097. Mol Oncol 5: 292–301.
-
(2011)
Mol Oncol
, vol.5
, pp. 292-301
-
-
He, W.1
Luistro, L.2
Carvajal, D.3
Smith, M.4
Nevins, T.5
Yin, X.6
-
22
-
-
67849124654
-
DLL 4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency
-
Hoey T. Yen W. Axelrod F. Basi J. Donigian L. Dylla S. et al. (2009) DLL 4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Cell Stem Cell 5: 168–177.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 168-177
-
-
Hoey, T.1
Yen, W.2
Axelrod, F.3
Basi, J.4
Donigian, L.5
Dylla, S.6
-
23
-
-
84855344803
-
Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB 2 breast cancer
-
Kondratyev M. Kreso A. Hallett R. Girgis-Gabardo A. Barcelon M. Ilieva D. et al. (2012) Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB 2 breast cancer. Oncogene 31: 93–103.
-
(2012)
Oncogene
, vol.31
, pp. 93-103
-
-
Kondratyev, M.1
Kreso, A.2
Hallett, R.3
Girgis-Gabardo, A.4
Barcelon, M.5
Ilieva, D.6
-
24
-
-
48549085976
-
Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis
-
Lee C. Raskett C. Prudovsky I. Altieri D. (2008 a) Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis. Cancer Res 68: 5273–5281.
-
(2008)
Cancer Res
, vol.68
, pp. 5273-5281
-
-
Lee, C.1
Raskett, C.2
Prudovsky, I.3
Altieri, D.4
-
26
-
-
36549010842
-
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
-
Leong K. Niessen K. Kulic I. Raouf A. Eaves C. Pollet I. et al. (2007) Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med 204: 2935–2948.
-
(2007)
J Exp Med
, vol.204
, pp. 2935-2948
-
-
Leong, K.1
Niessen, K.2
Kulic, I.3
Raouf, A.4
Eaves, C.5
Pollet, I.6
-
27
-
-
43149113910
-
Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3
-
Li K. Li Y. Wu W. Gordon W. Chang D. Lu M. et al. (2008) Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3. J Biol Chem 283: 8046–8054.
-
(2008)
J Biol Chem
, vol.283
, pp. 8046-8054
-
-
Li, K.1
Li, Y.2
Wu, W.3
Gordon, W.4
Chang, D.5
Lu, M.6
-
28
-
-
84877897704
-
Distinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies
-
Li Y. Burns J. Cheney C. Zhang N. Vitelli S. Wang F. et al. (2010) Distinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies. Biologics 4: 163–171.
-
(2010)
Biologics
, vol.4
, pp. 163-171
-
-
Li, Y.1
Burns, J.2
Cheney, C.3
Zhang, N.4
Vitelli, S.5
Wang, F.6
-
29
-
-
68349130357
-
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA 1 mutation carriers
-
Lim E. Vaillant F. Wu D. Forrest N. Pal B. Hart A. et al. (2009) Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA 1 mutation carriers. Nat Med 15: 907–913.
-
(2009)
Nat Med
, vol.15
, pp. 907-913
-
-
Lim, E.1
Vaillant, F.2
Wu, D.3
Forrest, N.4
Pal, B.5
Hart, A.6
-
30
-
-
77957591579
-
Targeting breast cancer stem cells
-
Liu S. Wicha M. (2010) Targeting breast cancer stem cells. J Clin Oncol 28: 4006–4012.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4006-4012
-
-
Liu, S.1
Wicha, M.2
-
31
-
-
79551510137
-
Notch 1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice
-
Liu Z. Turkoz A. Jackson E. Corbo J. Engelbach J. Garbow J. et al. (2011) Notch 1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice. J Clin Invest 121: 800–808.
-
(2011)
J Clin Invest
, vol.121
, pp. 800-808
-
-
Liu, Z.1
Turkoz, A.2
Jackson, E.3
Corbo, J.4
Engelbach, J.5
Garbow, J.6
-
32
-
-
0034192461
-
Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters
-
Lowell S. Jones P. Le Roux I. Dunne J. Watt F. (2000) Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. Curr Biol 10: 491–500.
-
(2000)
Curr Biol
, vol.10
, pp. 491-500
-
-
Lowell, S.1
Jones, P.2
Le Roux, I.3
Dunne, J.4
Watt, F.5
-
33
-
-
77950441537
-
Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells
-
Mazzone M. Selfors L. Albeck J. Overholtzer M. Sale S. Carroll D. et al. (2010) Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells. Proc Natl Acad Sci U S A 107: 5012–5017.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 5012-5017
-
-
Mazzone, M.1
Selfors, L.2
Albeck, J.3
Overholtzer, M.4
Sale, S.5
Carroll, D.6
-
34
-
-
67449116604
-
Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells
-
Meurette O. Stylianou S. Rock R. Collu G. Gilmore A. Brennan K. (2009) Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells. Cancer Res 69: 5015–5022.
-
(2009)
Cancer Res
, vol.69
, pp. 5015-5022
-
-
Meurette, O.1
Stylianou, S.2
Rock, R.3
Collu, G.4
Gilmore, A.5
Brennan, K.6
-
35
-
-
74549133972
-
Cooperation of Notch and Ras / MAPK signaling pathways in human breast carcinogenesis
-
Mittal S. Subramanyam D. Dey D. Kumar R. Rangarajan A. (2009) Cooperation of Notch and Ras / MAPK signaling pathways in human breast carcinogenesis. Mol Cancer 8: 128.
-
(2009)
Mol Cancer
, vol.8
, pp. 128
-
-
Mittal, S.1
Subramanyam, D.2
Dey, D.3
Kumar, R.4
Rangarajan, A.5
-
37
-
-
0033867521
-
A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1
-
Mumm J. Schroeter E. Saxena M. Griesemer A. Tian X. Pan D. et al. (2000) A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1. Mol Cell 5: 197–206.
-
(2000)
Mol Cell
, vol.5
, pp. 197-206
-
-
Mumm, J.1
Schroeter, E.2
Saxena, M.3
Griesemer, A.4
Tian, X.5
Pan, D.6
-
39
-
-
34548833559
-
Notch 2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth
-
O'Neill C. Urs S. Cinelli C. Lincoln A. Nadeau R. Leon R. et al. (2007) Notch 2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth. Am J Pathol 171: 1023–1036.
-
(2007)
Am J Pathol
, vol.171
, pp. 1023-1036
-
-
O'Neill, C.1
Urs, S.2
Cinelli, C.3
Lincoln, A.4
Nadeau, R.5
Leon, R.6
-
40
-
-
18644367748
-
Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1
-
Okochi M. Steiner H. Fukumori A. Tanii H. Tomita T. Tanaka T. et al. (2002) Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1. EMBO J 21: 5408–5416.
-
(2002)
EMBO J
, vol.21
, pp. 5408-5416
-
-
Okochi, M.1
Steiner, H.2
Fukumori, A.3
Tanii, H.4
Tomita, T.5
Tanaka, T.6
-
41
-
-
50649125794
-
ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor
-
Osipo C. Patel P. Rizzo P. Clementz A. Hao L. Golde T. et al. (2008) ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor. Oncogene 27: 5019–5032.
-
(2008)
Oncogene
, vol.27
, pp. 5019-5032
-
-
Osipo, C.1
Patel, P.2
Rizzo, P.3
Clementz, A.4
Hao, L.5
Golde, T.6
-
42
-
-
80052494506
-
Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence
-
Pandya K. Meeke K. Clementz A. Rogowski A. Roberts J. Miele L. et al. (2011) Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence. Br J Cancer 105: 796–806.
-
(2011)
Br J Cancer
, vol.105
, pp. 796-806
-
-
Pandya, K.1
Meeke, K.2
Clementz, A.3
Rogowski, A.4
Roberts, J.5
Miele, L.6
-
44
-
-
0034051852
-
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
-
Parks A. Klueg K. Stout J. Muskavitch M. (2000) Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. Development 127: 1373–1385.
-
(2000)
Development
, vol.127
, pp. 1373-1385
-
-
Parks, A.1
Klueg, K.2
Stout, J.3
Muskavitch, M.4
-
45
-
-
14244269366
-
The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer
-
Parr C. Watkins G. Jiang W. (2004) The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer. Int J Mol Med 14: 779–786.
-
(2004)
Int J Mol Med
, vol.14
, pp. 779-786
-
-
Parr, C.1
Watkins, G.2
Jiang, W.3
-
46
-
-
7244250027
-
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
-
Pece S. Serresi M. Santolini E. Capra M. Hulleman E. Galimberti V. et al. (2004) Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J Cell Biol 167: 215–221.
-
(2004)
J Cell Biol
, vol.167
, pp. 215-221
-
-
Pece, S.1
Serresi, M.2
Santolini, E.3
Capra, M.4
Hulleman, E.5
Galimberti, V.6
-
47
-
-
79953204955
-
Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells
-
Pellegrinet L. Rodilla V. Liu Z. Chen S. Koch U. Espinosa L. et al. (2011) Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells. Gastroenterology 140: 1230–1240, e1231–1237.
-
(2011)
Gastroenterology
, vol.140
, pp. 1230-1240
-
-
Pellegrinet, L.1
Rodilla, V.2
Liu, Z.3
Chen, S.4
Koch, U.5
Espinosa, L.6
-
48
-
-
68349150810
-
Mammary development meets cancer genomics
-
Prat A. Perou C. (2009) Mammary development meets cancer genomics. Nat Med 15: 842–844.
-
(2009)
Nat Med
, vol.15
, pp. 842-844
-
-
Prat, A.1
Perou, C.2
-
49
-
-
80053570445
-
Fringe benefits: functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptors
-
Rana N. Haltiwanger R. (2011) Fringe benefits: functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptors. Curr Opin Struct Biol 21: 583–589.
-
(2011)
Curr Opin Struct Biol
, vol.21
, pp. 583-589
-
-
Rana, N.1
Haltiwanger, R.2
-
50
-
-
17844384528
-
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
-
Rangarajan A. Talora C. Okuyama R. Nicolas M. Mammucari C. Oh H. et al. (2001) Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J 20: 3427–3436.
-
(2001)
EMBO J
, vol.20
, pp. 3427-3436
-
-
Rangarajan, A.1
Talora, C.2
Okuyama, R.3
Nicolas, M.4
Mammucari, C.5
Oh, H.6
-
51
-
-
24944506696
-
High-level coexpression of JAG 1 and NOTCH 1 is observed in human breast cancer and is associated with poor overall survival
-
Reedijk M. Odorcic S. Chang L. Zhang H. Miller N. McCready D. et al. (2005) High-level coexpression of JAG 1 and NOTCH 1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 65: 8530–8537.
-
(2005)
Cancer Res
, vol.65
, pp. 8530-8537
-
-
Reedijk, M.1
Odorcic, S.2
Chang, L.3
Zhang, H.4
Miller, N.5
McCready, D.6
-
52
-
-
51649090695
-
JAG 1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer
-
Reedijk M. Pinnaduwage D. Dickson B. Mulligan A. Zhang H. Bull S. et al. (2008) JAG 1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer. Breast Cancer Res Treat 111: 439–448.
-
(2008)
Breast Cancer Res Treat
, vol.111
, pp. 439-448
-
-
Reedijk, M.1
Pinnaduwage, D.2
Dickson, B.3
Mulligan, A.4
Zhang, H.5
Bull, S.6
-
53
-
-
48549103124
-
Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches
-
Rizzo P. Miao H. D'Souza G. Osipo C. Song L. Yun J. et al. (2008) Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res 68: 5226–5235.
-
(2008)
Cancer Res
, vol.68
, pp. 5226-5235
-
-
Rizzo, P.1
Miao, H.2
D'Souza, G.3
Osipo, C.4
Song, L.5
Yun, J.6
-
54
-
-
84856091317
-
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer
-
Robinson D. Kalyana-Sundaram S. Wu Y. Shankar S. Cao X. Ateeq B. et al. (2011) Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer. Nat Med 17: 1646–1651.
-
(2011)
Nat Med
, vol.17
, pp. 1646-1651
-
-
Robinson, D.1
Kalyana-Sundaram, S.2
Wu, Y.3
Shankar, S.4
Cao, X.5
Ateeq, B.6
-
56
-
-
79955481383
-
The Notch signaling pathway: molecular basis of cell context dependency
-
Schwanbeck R. Martini S. Bernoth K. Just U. (2011) The Notch signaling pathway: molecular basis of cell context dependency. Eur J Cell Biol 90: 572–581.
-
(2011)
Eur J Cell Biol
, vol.90
, pp. 572-581
-
-
Schwanbeck, R.1
Martini, S.2
Bernoth, K.3
Just, U.4
-
57
-
-
32944470488
-
Aberrant activation of notch signaling in human breast cancer
-
Stylianou S. Clarke R. Brennan K. (2006) Aberrant activation of notch signaling in human breast cancer. Cancer Res 66: 1517–1525.
-
(2006)
Cancer Res
, vol.66
, pp. 1517-1525
-
-
Stylianou, S.1
Clarke, R.2
Brennan, K.3
-
58
-
-
9144246932
-
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
-
Timmerman L. Grego-Bessa J. Raya A. Bertran E. Perez-Pomares J. Diez J. et al. (2004) Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev 18: 99–115.
-
(2004)
Genes Dev
, vol.18
, pp. 99-115
-
-
Timmerman, L.1
Grego-Bessa, J.2
Raya, A.3
Bertran, E.4
Perez-Pomares, J.5
Diez, J.6
-
59
-
-
20544460148
-
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
van Es J. van Gijn M. Riccio O. van den Born M. Vooijs M. Begthel H. et al. (2005) Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435: 959–963.
-
(2005)
Nature
, vol.435
, pp. 959-963
-
-
van Es, J.1
van Gijn, M.2
Riccio, O.3
van den Born, M.4
Vooijs, M.5
Begthel, H.6
-
61
-
-
71549114204
-
de novo discovery of a gamma-secretase inhibitor response signature using a novel in vivo breast tumor model
-
Watters J. Cheng C. Majumder P. Wang R. Yalavarthi S. Meeske C. et al. (2009) de novo discovery of a gamma-secretase inhibitor response signature using a novel in vivo breast tumor model. Cancer Res 69: 8949–8957.
-
(2009)
Cancer Res
, vol.69
, pp. 8949-8957
-
-
Watters, J.1
Cheng, C.2
Majumder, P.3
Wang, R.4
Yalavarthi, S.5
Meeske, C.6
-
63
-
-
40949092796
-
NOTCH 3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells
-
Yamaguchi N. Oyama T. Ito E. Satoh H. Azuma S. Hayashi M. et al. (2008) NOTCH 3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells. Cancer Res 68: 1881–1888.
-
(2008)
Cancer Res
, vol.68
, pp. 1881-1888
-
-
Yamaguchi, N.1
Oyama, T.2
Ito, E.3
Satoh, H.4
Azuma, S.5
Hayashi, M.6
-
65
-
-
12944255642
-
Fringe glycosyltransferases differentially modulate Notch 1 proteolysis induced by Delta 1 and Jagged1
-
Yang L. Nichols J. Yao C. Manilay J. Robey E. Weinmaster G. (2005) Fringe glycosyltransferases differentially modulate Notch 1 proteolysis induced by Delta 1 and Jagged1. Mol Biol Cell 16: 927–942.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 927-942
-
-
Yang, L.1
Nichols, J.2
Yao, C.3
Manilay, J.4
Robey, E.5
Weinmaster, G.6
-
67
-
-
77949457142
-
RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer
-
Zang S. Chen F. Dai J. Guo D. Tse W. Qu X. et al. (2010) RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer. Oncol Rep 23: 893–899.
-
(2010)
Oncol Rep
, vol.23
, pp. 893-899
-
-
Zang, S.1
Chen, F.2
Dai, J.3
Guo, D.4
Tse, W.5
Qu, X.6
-
68
-
-
77449089220
-
High Notch 1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype
-
Zardawi S. Zardawi I. McNeil C. Millar E. McLeod D. Morey A. et al. (2010) High Notch 1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype. Histopathology 56: 286–296.
-
(2010)
Histopathology
, vol.56
, pp. 286-296
-
-
Zardawi, S.1
Zardawi, I.2
McNeil, C.3
Millar, E.4
McLeod, D.5
Morey, A.6
-
69
-
-
1842524153
-
Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition
-
Zavadil J. Cermak L. Soto-Nieves N. Bottinger E. (2004) Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition. EMBO J 23: 1155–1165.
-
(2004)
EMBO J
, vol.23
, pp. 1155-1165
-
-
Zavadil, J.1
Cermak, L.2
Soto-Nieves, N.3
Bottinger, E.4
-
70
-
-
22244460522
-
Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling
-
Zeng Q. Li S. Chepeha D. Giordano T. Li J. Zhang H. et al. (2005) Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling. Cancer Cell 8: 13–23.
-
(2005)
Cancer Cell
, vol.8
, pp. 13-23
-
-
Zeng, Q.1
Li, S.2
Chepeha, D.3
Giordano, T.4
Li, J.5
Zhang, H.6
|