Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator

Journal of Immunology

Volumn 190, Issue 10, 2013, Pages 5196-5206

  Zhang, Ping Xia ^a   Murray, Thomas S ^a,b   Villella, Valeria R ^c   Ferrari, Eleonora ^c   Esposito, Speranza ^c   D'Souza, Anthony ^a   Raia, Valeria ^d   Maiuri, Luigi ^c,e   Krause, Diane S ^a   Egan, Marie E ^a   Bruscia, Emanuela M ^a,c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Quinnipiac University   (United States)

^c SAN RAFFAELE HOSPITAL   (Italy)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e UNIVERSITY OF FOGGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; CAVEOLIN 1; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HEME OXYGENASE 1; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4;

ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CASE REPORT; CELL COMPARTMENTALIZATION; CELL SURFACE; CELL SURVIVAL; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG TARGETING; ENZYME INDUCTION; ENZYME LOCALIZATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERINFLAMMATION; INFLAMMATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

ADOLESCENT; ADULT; ANIMALS; CAVEOLIN 1; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FEMALE; HEME OXYGENASE-1; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; LUNG DISEASES; MACROPHAGES; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NASAL POLYPS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; YOUNG ADULT;

EID: 84877818142     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201607     Document Type: Article

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