Induction of type I interferon signaling by Pseudomonas aeruginosa is diminished in cystic fibrosis epithelial cells

American Journal of Respiratory Cell and Molecular Biology

Volumn 46, Issue 1, 2012, Pages 6-13

  Parker, Dane ^a   Cohen, Taylor S ^a   Alhede, Morten ^a   Harfenist, Bryan S ^a   Martin, Francis J ^a   Prince, Alice ^a  

^a Columbia University ^*  (United States)

Author keywords

Cystic fibrosis; Pseudomonas aeruginosa; TLR4; Type I interferon

Indexed keywords

BETA INTERFERON; CD86 ANTIGEN; GLYCOPROTEIN P 15095; INTERFERON; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN MD 2; STAT1 PROTEIN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL COLONIZATION; CONTROLLED STUDY; CYSTIC FIBROSIS; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOSURVEILLANCE; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PNEUMONIA; RESPIRATORY EPITHELIUM; SUPERNATANT;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTIGENS, CD11C; ANTIGENS, CD86; CELLS, CULTURED; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DENDRITIC CELLS; EPITHELIAL CELLS; HUMANS; INTERFERON TYPE I; INTERFERON-BETA; LYMPHOCYTE ANTIGEN 96; MICE; MICE, INBRED C57BL; MUTATION; PHOSPHORYLATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTOR 4;

MURINAE; PSEUDOMONAS AERUGINOSA;

EID: 84855394399     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0080OC     Document Type: Article

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