A new role for myeloid HO-1 in the innate to adaptive crosstalk and immune homeostasis

Advances in Experimental Medicine and Biology

Volumn 780, Issue , 2011, Pages 101-111

  Koliaraki, Vasiliki ^a   Kollias, George ^a  

^a BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; BILIRUBIN; BILIVERDIN; CARBON MONOXIDE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 17; POLYINOSINIC POLYCYTIDYLIC ACID; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4;

ADAPTIVE IMMUNITY; ALLERGIC ENCEPHALOMYELITIS; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ATHEROSCLEROSIS; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELL PROTECTION; COMPLEX FORMATION; CONFERENCE PAPER; CYTOKINE PRODUCTION; ENZYME ACTIVITY; FIBROBLAST; GENE INDUCTION; GRAFT REJECTION; HUMAN; IMMUNOMODULATION; IMMUNOREGULATION; INFECTION; INFLAMMATORY DISEASE; INNATE IMMUNITY; INTERFERON INDUCTION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SYSTEMIC LUPUS ERYTHEMATOSUS; UPREGULATION;

ADAPTIVE IMMUNITY; ANIMALS; DEAD-BOX RNA HELICASES; GENE EXPRESSION; HEME; HEME OXYGENASE-1; HOMEOSTASIS; HUMANS; IMMUNITY, INNATE; INFLAMMATION; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; MICE; MICE, KNOCKOUT; MYELOID CELLS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TRANSCRIPTIONAL ACTIVATION;

MUS;

EID: 80053606277     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-5632-3_9     Document Type: Conference Paper

References (77)

1. Adachi T, Ishikawa K, Hida W et al (2004) Hypoxemia and blunted hypoxic ventilatory responses in mice lacking heme oxygenase-2. Biochem Biophys Res Commun 320(2): 514-522 (Pubitemid 38798898)
2. Akira S, Takeda K (2004) Toll-like receptor signaling. Nat Rev Immunol 4(7):499-511
3. Amersi F, Shen XD, Anselmo D et al (2002) Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway. Hepatology 35(4):815-823 (Pubitemid 34258375)
4. Benallaoua M, Francois M, Batteux F et al (2007) Pharmacologic induction of heme oxygenase 1 reduces acute inflammatory arthritis in mice. Arthritis Rheum 56(8):2585-2594 (Pubitemid 47237277)
5. Blydt-Hansen TD, Katori M, Lassman C et al (2003) Gene transfer-induced local heme oxy-genase-1 over-expression protects rat kidney transplants from ischemia/reperfusion injury. J Am Soc Nephrol 14(3):745-754 (Pubitemid 36246020)
6. Brouard S, Berberat PO, Tobiasch E et al (2002) Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis. J Biol Chem 277(20):17950-17961 (Pubitemid 34967606)
7. Chora AA, Fontoura P, Cunha A et al (2007) Heme oxygenase-1 and carbon monoxide suppress auto-immune neuroinflammation. J Clin Invest 117(2):438-447 (Pubitemid 46203972)
8. Chung SW, Liu X, Macias AA et al (2008) Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice. J Clin Invest 118(1):239-247
9. Cruse I, Maines MD (1988) Evidence suggesting that the two forms of heme oxygenase are products of different genes. J Biol Chem 263(7):3348-3353 (Pubitemid 18072793)
10. Exner M, Minar E, Wagner O et al (2004) The role of heme oxygenase-1 promoter polymorphisms in human disease. Free Radic Biol Med 37(8):1097-1104 (Pubitemid 39296737)
11. Ferrandiz ML, Maicas N, Garcia-Arnandis I et al (2008) Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis. Ann Rheum Dis 67(9):1211-1217
12. Fondevila C, Shen XD, Tsuchiyashi S et al (2004) Biliverdin therapy protects rat livers from ischemia and reperfusion injury. Hepatology 40(6):1333-1341 (Pubitemid 39657007)
13. Goldberg A, Parolini M, Chin BY et al (2007) Toll-like receptor 4 suppression leads to islet allograft survival. FASEB J 21(11):2840-2848 (Pubitemid 47372751)
14. Gong Q, Yin H, Fang M et al (2008) Heme oxygenase-1 upregulation significantly inhibits TNF-alpha and Hmgb1 releasing and attenuates lipopolysaccharide-induced acute lung injury in mice. Int Immunopharmacol 8(6):792-798
15. Gunther L, Berberat PO, Haga M et al (2002) Carbon monoxide protects pancreatic beta-cells from apoptosis and improves islet function/survival after transplantation. Diabetes 51(4):994-999 (Pubitemid 34438341)
16. Hashiba T, Suzuki M, Nagashima Y et al (2001) Adenovirus-mediated transfer of heme oxygenase-1 cDNA attenuates severe lung injury induced by the influenza virus in mice. Gene Ther 8(19):1499-1507 (Pubitemid 32994661)
17. Hayashi S, Omata Y, Sakamoto H et al (2004) Characterization of rat heme oxygenase-3 gene. Implication of processed pseudogenes derived from heme oxygenase-2 gene. Gene 336(2):241-250 (Pubitemid 38891741)
18. Hoebe K, Janssen E, Beutler B (2004) The interface between innate and adaptive immunity. Nat Immunol 5(10):971-974 (Pubitemid 41057712)
19. Hu CM, Lin HH, Chiang MT et al (2007) Systemic expression of heme oxygenase-1 ameliorates type 1 diabetes in NOD mice. Diabetes 56(5):1240-1247
20. Ishikawa K, Sugawara D, Goto J et al (2001) Heme oxygenase-1 inhibits atherogenesis in Watanabe heritable hyperlipidemic rabbits. Circulation 104(15):1831-1836 (Pubitemid 32963350)
21. Ishikawa K, Sugawara D, Wang X et al (2001) Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knock-out mice. Circ Res 88(5):506-512 (Pubitemid 32240914)
22. Iwasaki A, Medzhitov R (2010) Regulation of adaptive immunity by the innate immune system. Science 327(5963):291-295
23. Juan SH, Lee TS, Tseng KW et al (2001) Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice. Circulation 104(13):1519-1525
24. Kato H, Takeuchi O, Sato S et al (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441(7089):101-105
25. Kawai T, Takahashi K, Sato S et al (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 6(10):981-988 (Pubitemid 41486182)
26. Kawashima A, Oda Y, Yachie A et al (2002) Heme oxygenase-1 deficiency: the first autopsy case. Hum Pathol 33(1):125-130 (Pubitemid 34112962)
27. Kim HS, Loughran PA, Rao J et al (2008) Carbon monoxide activates NF-kappaB via ROS generation and Akt pathways to protect against cell death of hepatocytes. Am J Physiol Gastrointest Liver Physiol 295(1):G146-G152
28. Kobayashi H, Takeno M, Saito T et al (2006) Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis. Arthritis Rheum 54(4):1132-1142 (Pubitemid 43672926)
29. Koizumi S (2007) Human heme oxygenase-1 deficiency: a lesson on serendipity in the discovery of the novel disease. Pediatr Int 49(2):125-132 (Pubitemid 46558301)
30. Le Bon A, Tough DF (2002) Links between innate and adaptive immunity via type I interferon. Curr Opin Immunol 14(4):432-436 (Pubitemid 34671244)
31. Lee TS, Chau LY (2002) Heme oxygenase-1 mediates the anti-inflammatory effect of interleu-kin-10 in mice. Nat Med 8(3):240-246
32. Li M, Peterson S, Husney D et al (2007) Long-lasting expression of HO-1 delays progression of type I diabetes in NOD mice. Cell Cycle 6(5):567-571 (Pubitemid 46440429)
33. Liu Y, Zhu B, Luo L et al (2001) Heme oxygenase-1 plays an important protective role in experimental auto-immune encephalomyelitis. Neuroreport 12(9):1841-1845 (Pubitemid 32553694)
34. Maines MD (1988) Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 2(10):2557-2568
35. Maines MD, Trakshel GM, Kutty RK (1986) Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible. J Biol Chem 261(1):411-419 (Pubitemid 16103962)
36. McCoubrey WK Jr, Huang TJ, Maines MD (1997) Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur J Biochem 247(2):725-732 (Pubitemid 27308655)
37. Medzhitov R (2001) Toll-like receptors and innate immunity. Nat Rev Immunol 1(2):135-145 (Pubitemid 33741967)
38. Megias J, Busserolles J, Alcaraz MJ (2007) The carbon monoxide-releasing molecule CORM-2 inhibits the inflammatory response induced by cytokines in Caco-2 cells. Br J Pharmacol 150(8):977-986 (Pubitemid 46625094)
39. Melo LG, Agrawal R, Zhang L et al (2002) Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene. Circulation 105(5):602-607 (Pubitemid 34123435)
40. Nakahira K, Kim HP, Geng XH et al (2006) Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J Exp Med 203(10):2377-2389 (Pubitemid 44498371)
41. Otterbein LE, Bach FH, Alam J et al (2000) Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 6(4):422-428 (Pubitemid 30208159)
42. Overhaus M, Moore BA, Barbato JE et al (2006) Biliverdin protects against polymicrobial sepsis by modulating inflammatory mediators. Am J Physiol Gastrointest Liver Physiol 290(4):G695-G703
43. Pae HO, Oh GS, Choi BM et al (2004) Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production. J Immunol 172(8):4744-4751
44. Pamplona A, Ferreira A, Balla J et al (2007) Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria. Nat Med 13(6):703-710 (Pubitemid 46889755)
45. Park SY, Lee SW, Shin HK et al (2010) Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxy-genase 1 induction. Arthritis Rheum 62(3):732-741
46. Perry AK, Chow EK, Goodnough JB et al (2004) Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection. J Exp Med 199(12):1651-1658 (Pubitemid 38821998)
47. Petrache I, Otterbein LE, Alam J et al (2000) Heme oxygenase-1 inhibits TNF-alpha-induced apoptosis in cultured fibroblasts. Am J Physiol Lung Cell Mol Physiol 278(2):L312-L319 (Pubitemid 30131216)
48. Poss KD, Tonegawa S (1997) Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci USA 94(20):10919-10924 (Pubitemid 27430836)
49. Poss KD, Tonegawa S (1997) Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci USA 94(20):10925-10930 (Pubitemid 27430837)
50. Protzer U, Seyfried S, Quasdorff M et al (2007) Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection. Gastroenterology 133(4):1156-1165 (Pubitemid 47500115)
51. Remy S, Blancou P, Tesson L et al (2009) Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity. J Immunol 182(4):1877-1884
52. Rock FL, Hardiman G, Timans JC et al (1998) A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci USA 95(2):588-593 (Pubitemid 28083787)
53. Rodella L, Lamon BD, Rezzani R et al (2006) Carbon monoxide and biliverdin prevent endothelial cell sloughing in rats with type I diabetes. Free Radic Biol Med 40(12):2198-2205 (Pubitemid 43903106)
54. Rodella LF, Vanella L, Peterson SJ et al (2008) Heme oxygenase-derived carbon monoxide restores vascular function in type 1 diabetes. Drug Metab Lett 2(4):290-300
55. Ryter SW, Alam J, Choi AM (2006) Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev 86(2):583-650
56. Saha SK, Pietras EM, He JQ et al (2006) Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif. EMBO J 25(14):3257-3263 (Pubitemid 44141784)
57. Sarady-Andrews JK, Liu F, Gallo D et al (2005) Biliverdin administration protects against endotoxin-induced acute lung injury in rats. Am J Physiol Lung Cell Mol Physiol 289(6): L1131-L1137 (Pubitemid 41681348)
58. Seth RB, Sun L, Ea CK et al (2005) Identification and characterization of MAVS, a mitochon-drial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122(5):669-682 (Pubitemid 41242633)
59. Suh GY, Jin Y, Yi AK et al (2006) CCAAT/enhancer-binding protein mediates carbon monoxide-induced suppression of cyclooxygenase-2. Am J Respir Cell Mol Biol 35(2):220-226 (Pubitemid 44175322)
60. Takamiya R, Hung CC, Hall SR et al (2009) High-mobility group box 1 contributes to lethality of endotoxemia in heme oxygenase-1-deficient mice. Am J Respir Cell Mol Biol 41(2): 129-135
61. Takeda K, Akira S (2005) Toll-like receptors in innate immunity. Int Immunol 17(1):1-14
62. Takeda Y, Takeno M, Iwasaki M et al (2004) Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody. Clin Exp Immunol 138(2):237-244 (Pubitemid 39472439)
63. Takeuchi O, Akira S (2008) MDA5/RIG-I and virus recognition. Curr Opin Immunol 20(1):17-22
64. Tenhunen R, Marver H, Pimstone NR et al (1972) Enzymatic degradation of heme. Oxygenative cleavage requiring cytochrome P-450. Biochemistry 11(9):1716-1720
65. Tenhunen R, Marver HS, Schmid R (1968) The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci USA 61(2):748-755
66. Tenhunen R, Marver HS, Schmid R (1969) The enzymatic conversion of hemoglobin to bilirubin. Trans Assoc Am Physicians 82:363-371
67. Tenhunen R, Marver HS, Schmid R (1969) Microsomal heme oxygenase. Characterization of the enzyme. J Biol Chem 244(23):6388-6394
68. Tsuchihashi S, Zhai Y, Bo Q et al (2007) Heme oxygenase-1 mediated cytoprotection against liver ischemia and reperfusion injury: inhibition of type-1 interferon signaling. Transplantation 83(12):1628-1634 (Pubitemid 46987916)
69. Tsuchihashi S, Zhai Y, Fondevila C et al (2005) HO-1 upregulation suppresses type 1 IFN pathway in hepatic ischemia/reperfusion injury. Transplant Proc 37(4):1677-1678 (Pubitemid 40790792)
70. Tzima S, Victoratos P, Kranidioti K et al (2009) Myeloid heme oxygenase-1 regulates innate immunity and auto-immunity by modulating IFN-beta production. J Exp Med 206(5): 1167-1179
71. Wang XM, Kim HP, Nakahira K et al (2009) The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1. J Immunol 182(6):3809-3818
72. Wiesel P, Patel AP, DiFonzo N et al (2000) Endotoxin-induced mortality is related to increased oxidative stress and end-organ dysfunction, not refractory hypotension, in heme oxygenase-1-deficient mice. Circulation 102(24):3015-3022
73. Wilks A (2002) Heme oxygenase: evolution, structure, and mechanism. Antioxid Redox Signal 4(4):603-614 (Pubitemid 35001444)
74. Yachie A, Niida Y, Wada T et al (1999) Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency. J Clin Invest 103(1):129-135 (Pubitemid 29031171)
75. Yet SF, Layne MD, Liu X et al (2003) Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling. FASEB J 17(12):1759-1761
76. Yet SF, Perrella MA, Layne MD et al (1999) Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. J Clin Invest 103(8):R23-R29 (Pubitemid 29207256)
77. Yoneyama M, Kikuchi M, Natsukawa T et al (2004) The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 5(7): 730-737 (Pubitemid 39023305)