CORM-3-derived CO modulates polymorphonuclear leukocyte migration across the vascular endothelium by reducing levels of cell surface-bound elastase

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 297, Issue 3, 2009, Pages

  Mizuguchi, Shinjiro ^a   Stephen, Jancy ^a   Bihari, Relka ^a   Markovic, Nevena ^a   Suehiro, Shigefumi ^b   Capretta, Alfredo ^c   Potter, Richard F ^a   Cepinskas, Gediminas ^a  

^a LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Carbon monoxide; Carbon monoxide releasing molecules; Leukocyte adhesion migration; Oxidative stress; Proteolytic enzymes; Sepsis; Systemic inflammation; Tricarbonylchloroglycinate ruthenium(II)

Indexed keywords

CARBON MONOXIDE; CARBON MONOXIDE RELEASING MOLECULE 3; CARBONYL DERIVATIVE; CHLORINE DERIVATIVE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GLYCINE DERIVATIVE; LEUKOCYTE ELASTASE; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; RUTHENIUM DERIVATIVE; TRICARBONYLCHLOROGLYCINATE RUTHENIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; DEGRANULATION; ENZYME ASSAY; ENZYME RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; LEUKOCYTE ROLLING; LUNG LAVAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; SEPSIS; VASCULAR ENDOTHELIUM;

ANIMALS; CARBON MONOXIDE; CELL ADHESION; CELL MIGRATION ASSAYS, LEUKOCYTE; CELL MOVEMENT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; LEUKOCYTE ELASTASE; LIPOPOLYSACCHARIDES; LUNG; MICE; MICE, INBRED C57BL; NEUTROPHILS; ORGANOMETALLIC COMPOUNDS; PERITONITIS; REACTIVE OXYGEN SPECIES; SEPSIS; UMBILICAL VEINS;

EID: 69249125391     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00305.2009     Document Type: Article

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