Protein processing and inflammatory signaling in cystic fibrosis: Challenges and therapeutic strategies

Current Molecular Medicine

Volumn 10, Issue 1, 2010, Pages 82-94

  Belcher, C N ^a   Vij, N ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

F508; CFTR; Cystic fibrosis; ERAD; IL 8; Neutrophil; NF B; Proteasome; Therapeutics; Ubiquitin

Indexed keywords

4 METHYL 2 (5 PHENYL 1H PYRAZOL 3 YL)PHENOL; ACETYLCYSTEINE; ATALUREN; ATAXIN 3; BETAINE; BORTEZOMIB; CHAPERONE; CHLORIDE ION; DENUFOSOL; DOCOSAHEXAENOIC ACID; DORNASE ALFA; DURAMYCIN; GLUTATHIONE; GLYCEROL; HEAT SHOCK PROTEIN 70; HISTONE DEACETYLASE 6; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INOSITOL; INTERLEUKIN 8; MANNITOL; PHENOL DERIVATIVE; PROTEASOME; SILDENAFIL; SORBITOL; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRIMETHYLAMINE OXIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VRT 532; VX 770; VX 809;

CHLORIDE TRANSPORT; CHRONIC LUNG DISEASE; CYSTIC FIBROSIS; DRUG RESEARCH; ENDOPLASMIC RETICULUM; HUMAN; INFLAMMATION; MOLECULAR IMAGING; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; INFLAMMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION;

EID: 77949461446     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652410791065408     Document Type: Review

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