-
1
-
-
69249136609
-
Structure and function of Na(+)-symporters with inverted repeats
-
J. Abramson, and E.M. Wright Structure and function of Na(+)-symporters with inverted repeats Curr. Opin. Struct. Biol. 19 2009 425 432
-
(2009)
Curr. Opin. Struct. Biol.
, vol.19
, pp. 425-432
-
-
Abramson, J.1
Wright, E.M.2
-
2
-
-
84858110981
-
Position of the third Na+ site in the aspartate transporter GltPh and the human glutamate transporter, EAAT1
-
T. Bastug, G. Heinzelmann, S. Kuyucak, M. Salim, R.J. Vandenberg, and R.M. Ryan Position of the third Na+ site in the aspartate transporter GltPh and the human glutamate transporter, EAAT1 PLoS ONE 7 2012 e33058
-
(2012)
PLoS ONE
, vol.7
, pp. 33058
-
-
Bastug, T.1
Heinzelmann, G.2
Kuyucak, S.3
Salim, M.4
Vandenberg, R.J.5
Ryan, R.M.6
-
3
-
-
0034529012
-
Arginine 447 plays a pivotal role in substrate interactions in a neuronal glutamate transporter
-
A. Bendahan, A. Armon, N. Madani, M.P. Kavanaugh, and B.I. Kanner Arginine 447 plays a pivotal role in substrate interactions in a neuronal glutamate transporter J. Biol. Chem. 275 2000 37436 37442
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 37436-37442
-
-
Bendahan, A.1
Armon, A.2
Madani, N.3
Kavanaugh, M.P.4
Kanner, B.I.5
-
4
-
-
0031732435
-
Physiological and pathological operation of glutamate transporters
-
B. Billups, D. Rossi, T. Oshima, O. Warr, M. Takahashi, M. Sarantis, M. Szatkowski, and D. Attwell Physiological and pathological operation of glutamate transporters Prog. Brain Res. 116 1998 45 57
-
(1998)
Prog. Brain Res.
, vol.116
, pp. 45-57
-
-
Billups, B.1
Rossi, D.2
Oshima, T.3
Warr, O.4
Takahashi, M.5
Sarantis, M.6
Szatkowski, M.7
Attwell, D.8
-
5
-
-
33846505059
-
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter
-
O. Boudker, R.M. Ryan, D. Yernool, K. Shimamoto, and E. Gouaux Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter Nature 445 2007 387 393
-
(2007)
Nature
, vol.445
, pp. 387-393
-
-
Boudker, O.1
Ryan, R.M.2
Yernool, D.3
Shimamoto, K.4
Gouaux, E.5
-
6
-
-
77956189075
-
Structural perspectives on secondary active transporters
-
O. Boudker, and G. Verdon Structural perspectives on secondary active transporters Trends Pharmacol. Sci. 31 2010 418 426
-
(2010)
Trends Pharmacol. Sci.
, vol.31
, pp. 418-426
-
-
Boudker, O.1
Verdon, G.2
-
7
-
-
84865425436
-
The solute carrier 6 family of transporters
-
S. Bröer, and U. Gether The solute carrier 6 family of transporters Br. J. Pharmacol. 167 2012 256 278
-
(2012)
Br. J. Pharmacol.
, vol.167
, pp. 256-278
-
-
Bröer, S.1
Gether, U.2
-
8
-
-
41449093586
-
Substrate binding and formation of an occluded state in the leucine transporter
-
L. Celik, B. Schiøtt, and E. Tajkhorshid Substrate binding and formation of an occluded state in the leucine transporter Biophys. J. 94 2008 1600 1612
-
(2008)
Biophys. J.
, vol.94
, pp. 1600-1612
-
-
Celik, L.1
Schiøtt, B.2
Tajkhorshid, E.3
-
9
-
-
77954383579
-
Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters
-
D.P. Claxton, M. Quick, L. Shi, F.D. de Carvalho, H. Weinstein, J.A. Javitch, and H.S. McHaourab Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters Nat. Struct. Mol. Biol. 17 2010 822 829
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 822-829
-
-
Claxton, D.P.1
Quick, M.2
Shi, L.3
De Carvalho, F.D.4
Weinstein, H.5
Javitch, J.A.6
McHaourab, H.S.7
-
10
-
-
77955644600
-
The 3-4 loop of an archaeal glutamate transporter homolog experiences ligand-induced structural changes and is essential for transport
-
E.L. Compton, E.M. Taylor, and J.A. Mindell The 3-4 loop of an archaeal glutamate transporter homolog experiences ligand-induced structural changes and is essential for transport Proc. Natl. Acad. Sci. USA 107 2010 12840 12845
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 12840-12845
-
-
Compton, E.L.1
Taylor, E.M.2
Mindell, J.A.3
-
11
-
-
73949133608
-
Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats
-
T.J. Crisman, S. Qu, B.I. Kanner, and L.R. Forrest Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats Proc. Natl. Acad. Sci. USA 106 2009 20752 20757
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20752-20757
-
-
Crisman, T.J.1
Qu, S.2
Kanner, B.I.3
Forrest, L.R.4
-
13
-
-
79951619800
-
The mechanism of substrate release by the aspartate transporter GltPh: Insights from simulations
-
J. DeChancie, I.H. Shrivastava, and I. Bahar The mechanism of substrate release by the aspartate transporter GltPh: insights from simulations Mol. Biosyst. 7 2011 832 842
-
(2011)
Mol. Biosyst.
, vol.7
, pp. 832-842
-
-
Dechancie, J.1
Shrivastava, I.H.2
Bahar, I.3
-
14
-
-
79955780433
-
Opposite movement of the external gate of a glutamate transporter homolog upon binding cotransported sodium compared with substrate
-
P.J. Focke, P. Moenne-Loccoz, and H.P. Larsson Opposite movement of the external gate of a glutamate transporter homolog upon binding cotransported sodium compared with substrate J. Neurosci. 31 2011 6255 6262
-
(2011)
J. Neurosci.
, vol.31
, pp. 6255-6262
-
-
Focke, P.J.1
Moenne-Loccoz, P.2
Larsson, H.P.3
-
15
-
-
73949083478
-
The rocking bundle: A mechanism for ion-coupled solute flux by symmetrical transporters
-
L.R. Forrest, and G. Rudnick The rocking bundle: a mechanism for ion-coupled solute flux by symmetrical transporters Physiology (Bethesda) 24 2009 377 386
-
(2009)
Physiology (Bethesda)
, vol.24
, pp. 377-386
-
-
Forrest, L.R.1
Rudnick, G.2
-
16
-
-
48349140230
-
Mechanism for alternating access in neurotransmitter transporters
-
L.R. Forrest, Y.W. Zhang, M.T. Jacobs, J. Gesmonde, L. Xie, B.H. Honig, and G. Rudnick Mechanism for alternating access in neurotransmitter transporters Proc. Natl. Acad. Sci. USA 105 2008 10338 10343
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 10338-10343
-
-
Forrest, L.R.1
Zhang, Y.W.2
Jacobs, M.T.3
Gesmonde, J.4
Xie, L.5
Honig, B.H.6
Rudnick, G.7
-
17
-
-
78650297251
-
The structural basis of secondary active transport mechanisms
-
L.R. Forrest, R. Krämer, and C. Ziegler The structural basis of secondary active transport mechanisms Biochim. Biophys. Acta 1807 2011 167 188
-
(2011)
Biochim. Biophys. Acta
, vol.1807
, pp. 167-188
-
-
Forrest, L.R.1
Krämer, R.2
Ziegler, C.3
-
19
-
-
84855716593
-
Investigating the mechanism of substrate uptake and release in the glutamate transporter homologue Glt(Ph) through metadynamics simulations
-
G. Grazioso, V. Limongelli, D. Branduardi, E. Novellino, C. De Micheli, A. Cavalli, and M. Parrinello Investigating the mechanism of substrate uptake and release in the glutamate transporter homologue Glt(Ph) through metadynamics simulations J. Am. Chem. Soc. 134 2012 453 463
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 453-463
-
-
Grazioso, G.1
Limongelli, V.2
Branduardi, D.3
Novellino, E.4
De Micheli, C.5
Cavalli, A.6
Parrinello, M.7
-
20
-
-
17744363326
-
Electrogenic glutamate transporters in the CNS: Molecular mechanism, pre-steady-state kinetics, and their impact on synaptic signaling
-
C. Grewer, and T. Rauen Electrogenic glutamate transporters in the CNS: molecular mechanism, pre-steady-state kinetics, and their impact on synaptic signaling J. Membr. Biol. 203 2005 1 20
-
(2005)
J. Membr. Biol.
, vol.203
, pp. 1-20
-
-
Grewer, C.1
Rauen, T.2
-
21
-
-
24344507684
-
Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other
-
C. Grewer, P. Balani, C. Weidenfeller, T. Bartusel, Z. Tao, and T. Rauen Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other Biochemistry 44 2005 11913 11923
-
(2005)
Biochemistry
, vol.44
, pp. 11913-11923
-
-
Grewer, C.1
Balani, P.2
Weidenfeller, C.3
Bartusel, T.4
Tao, Z.5
Rauen, T.6
-
22
-
-
34548148634
-
Rigidity of the subunit interfaces of the trimeric glutamate transporter GltT during translocation
-
M. Groeneveld, and D.J. Slotboom Rigidity of the subunit interfaces of the trimeric glutamate transporter GltT during translocation J. Mol. Biol. 372 2007 565 570
-
(2007)
J. Mol. Biol.
, vol.372
, pp. 565-570
-
-
Groeneveld, M.1
Slotboom, D.J.2
-
23
-
-
77951680965
-
Na(+):aspartate coupling stoichiometry in the glutamate transporter homologue Glt(Ph)
-
M. Groeneveld, and D.J. Slotboom Na(+):aspartate coupling stoichiometry in the glutamate transporter homologue Glt(Ph) Biochemistry 49 2010 3511 3513
-
(2010)
Biochemistry
, vol.49
, pp. 3511-3513
-
-
Groeneveld, M.1
Slotboom, D.J.2
-
25
-
-
51649088013
-
Dynamics of the extracellular gate and ion-substrate coupling in the glutamate transporter
-
Z. Huang, and E. Tajkhorshid Dynamics of the extracellular gate and ion-substrate coupling in the glutamate transporter Biophys. J. 95 2008 2292 2300
-
(2008)
Biophys. J.
, vol.95
, pp. 2292-2300
-
-
Huang, Z.1
Tajkhorshid, E.2
-
26
-
-
77956527543
-
Identification of the third Na+ site and the sequence of extracellular binding events in the glutamate transporter
-
Z. Huang, and E. Tajkhorshid Identification of the third Na+ site and the sequence of extracellular binding events in the glutamate transporter Biophys. J. 99 2010 1416 1425
-
(2010)
Biophys. J.
, vol.99
, pp. 1416-1425
-
-
Huang, Z.1
Tajkhorshid, E.2
-
27
-
-
63249114685
-
The role of cation binding in determining substrate selectivity of glutamate transporters
-
S. Huang, R.M. Ryan, and R.J. Vandenberg The role of cation binding in determining substrate selectivity of glutamate transporters J. Biol. Chem. 284 2009 4510 4515
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 4510-4515
-
-
Huang, S.1
Ryan, R.M.2
Vandenberg, R.J.3
-
28
-
-
0014029736
-
Simple allosteric model for membrane pumps
-
O. Jardetzky Simple allosteric model for membrane pumps Nature 211 1966 969 970
-
(1966)
Nature
, vol.211
, pp. 969-970
-
-
Jardetzky, O.1
-
29
-
-
84877303485
-
A comparative study of structures and structural transitions of secondary transporters with the LeuT fold
-
G. Jeschke A comparative study of structures and structural transitions of secondary transporters with the LeuT fold Eur. Biophys. J. 42 2013 181 197
-
(2013)
Eur. Biophys. J.
, vol.42
, pp. 181-197
-
-
Jeschke, G.1
-
30
-
-
84862802974
-
Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å
-
Z.L. Johnson, C.G. Cheong, and S.Y. Lee Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å Nature 483 2012 489 493
-
(2012)
Nature
, vol.483
, pp. 489-493
-
-
Johnson, Z.L.1
Cheong, C.G.2
Lee, S.Y.3
-
31
-
-
0242469279
-
The glutamate and neutral amino acid transporter family: Physiological and pharmacological implications
-
Y. Kanai, and M.A. Hediger The glutamate and neutral amino acid transporter family: physiological and pharmacological implications Eur. J. Pharmacol. 479 2003 237 247
-
(2003)
Eur. J. Pharmacol.
, vol.479
, pp. 237-247
-
-
Kanai, Y.1
Hediger, M.A.2
-
32
-
-
84868108835
-
Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP
-
K. Khafizov, C. Perez, C. Koshy, M. Quick, K. Fendler, C. Ziegler, and L.R. Forrest Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP Proc. Natl. Acad. Sci. USA 109 2012 E3035 E3044
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
-
-
Khafizov, K.1
Perez, C.2
Koshy, C.3
Quick, M.4
Fendler, K.5
Ziegler, C.6
Forrest, L.R.7
-
33
-
-
14044263640
-
Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters
-
H.P. Koch, and H.P. Larsson Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters J. Neurosci. 25 2005 1730 1736
-
(2005)
J. Neurosci.
, vol.25
, pp. 1730-1736
-
-
Koch, H.P.1
Larsson, H.P.2
-
34
-
-
33947318986
-
The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits
-
H.P. Koch, R.L. Brown, and H.P. Larsson The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits J. Neurosci. 27 2007 2943 2947
-
(2007)
J. Neurosci.
, vol.27
, pp. 2943-2947
-
-
Koch, H.P.1
Brown, R.L.2
Larsson, H.P.3
-
35
-
-
84856225222
-
X-ray structures of LeuT in substrate-free outward-open and apo inward-open states
-
H. Krishnamurthy, and E. Gouaux X-ray structures of LeuT in substrate-free outward-open and apo inward-open states Nature 481 2012 469 474
-
(2012)
Nature
, vol.481
, pp. 469-474
-
-
Krishnamurthy, H.1
Gouaux, E.2
-
36
-
-
66249098083
-
Unlocking the molecular secrets of sodium-coupled transporters
-
H. Krishnamurthy, C.L. Piscitelli, and E. Gouaux Unlocking the molecular secrets of sodium-coupled transporters Nature 459 2009 347 355
-
(2009)
Nature
, vol.459
, pp. 347-355
-
-
Krishnamurthy, H.1
Piscitelli, C.L.2
Gouaux, E.3
-
37
-
-
79960673062
-
SLC6 neurotransmitter transporters: Structure, function, and regulation
-
A.S. Kristensen, J. Andersen, T.N. Jørgensen, L. Sørensen, J. Eriksen, C.J. Loland, K. Strømgaard, and U. Gether SLC6 neurotransmitter transporters: structure, function, and regulation Pharmacol. Rev. 63 2011 585 640
-
(2011)
Pharmacol. Rev.
, vol.63
, pp. 585-640
-
-
Kristensen, A.S.1
Andersen, J.2
Jørgensen, T.N.3
Sørensen, L.4
Eriksen, J.5
Loland, C.J.6
Strømgaard, K.7
Gether, U.8
-
39
-
-
77956362466
-
Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model
-
H.P. Larsson, X. Wang, B. Lev, I. Baconguis, D.A. Caplan, N.P. Vyleta, H.P. Koch, A. Diez-Sampedro, and S.Y. Noskov Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model Proc. Natl. Acad. Sci. USA 107 2010 13912 13917
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 13912-13917
-
-
Larsson, H.P.1
Wang, X.2
Lev, B.3
Baconguis, I.4
Caplan, D.A.5
Vyleta, N.P.6
Koch, H.P.7
Diez-Sampedro, A.8
Noskov, S.Y.9
-
40
-
-
33947308773
-
The glutamate and chloride permeation pathways are colocalized in individual neuronal glutamate transporter subunits
-
G.P. Leary, E.F. Stone, D.C. Holley, and M.P. Kavanaugh The glutamate and chloride permeation pathways are colocalized in individual neuronal glutamate transporter subunits J. Neurosci. 27 2007 2938 2942
-
(2007)
J. Neurosci.
, vol.27
, pp. 2938-2942
-
-
Leary, G.P.1
Stone, E.F.2
Holley, D.C.3
Kavanaugh, M.P.4
-
41
-
-
0030292906
-
Listening to neurotransmitter transporters
-
H.A. Lester, Y. Cao, and S. Mager Listening to neurotransmitter transporters Neuron 17 1996 807 810
-
(1996)
Neuron
, vol.17
, pp. 807-810
-
-
Lester, H.A.1
Cao, Y.2
Mager, S.3
-
42
-
-
84858763413
-
Constraints imposed by the membrane selectively guide the alternating access dynamics of the glutamate transporter GltPh
-
T.R. Lezon, and I. Bahar Constraints imposed by the membrane selectively guide the alternating access dynamics of the glutamate transporter GltPh Biophys. J. 102 2012 1331 1340
-
(2012)
Biophys. J.
, vol.102
, pp. 1331-1340
-
-
Lezon, T.R.1
Bahar, I.2
-
43
-
-
33748713433
-
The substrate specificity of a neuronal glutamate transporter is determined by the nature of the coupling ion
-
D. Menaker, A. Bendahan, and B.I. Kanner The substrate specificity of a neuronal glutamate transporter is determined by the nature of the coupling ion J. Neurochem. 99 2006 20 28
-
(2006)
J. Neurochem.
, vol.99
, pp. 20-28
-
-
Menaker, D.1
Bendahan, A.2
Kanner, B.I.3
-
44
-
-
0001398337
-
A general theory of membrane transport from studies of bacteria
-
P. Mitchell A general theory of membrane transport from studies of bacteria Nature 180 1957 134 136
-
(1957)
Nature
, vol.180
, pp. 134-136
-
-
Mitchell, P.1
-
45
-
-
51249194404
-
Contributions to the theory of active transport. II. The gate type non-carrier mechanism and generalizations concerning tracer flow, efficiency, and measurement of energy expenditure
-
C.S. Patlak Contributions to the theory of active transport. II. The gate type non-carrier mechanism and generalizations concerning tracer flow, efficiency, and measurement of energy expenditure Bull. Math. Biophys. 19 1957 209 235
-
(1957)
Bull. Math. Biophys.
, vol.19
, pp. 209-235
-
-
Patlak, C.S.1
-
46
-
-
84855351908
-
Insights into transport mechanism from LeuT engineered to transport tryptophan
-
C.L. Piscitelli, and E. Gouaux Insights into transport mechanism from LeuT engineered to transport tryptophan EMBO J. 31 2012 228 235
-
(2012)
EMBO J.
, vol.31
, pp. 228-235
-
-
Piscitelli, C.L.1
Gouaux, E.2
-
47
-
-
65249169367
-
Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation
-
M. Quick, A.M. Winther, L. Shi, P. Nissen, H. Weinstein, and J.A. Javitch Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation Proc. Natl. Acad. Sci. USA 106 2009 5563 5568
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 5563-5568
-
-
Quick, M.1
Winther, A.M.2
Shi, L.3
Nissen, P.4
Weinstein, H.5
Javitch, J.A.6
-
48
-
-
84856709995
-
Experimental conditions can obscure the second high-affinity site in LeuT
-
M. Quick, L. Shi, B. Zehnpfennig, H. Weinstein, and J.A. Javitch Experimental conditions can obscure the second high-affinity site in LeuT Nat. Struct. Mol. Biol. 19 2012 207 211
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 207-211
-
-
Quick, M.1
Shi, L.2
Zehnpfennig, B.3
Weinstein, H.4
Javitch, J.A.5
-
49
-
-
72449164409
-
Transport mechanism of a bacterial homologue of glutamate transporters
-
N. Reyes, C. Ginter, and O. Boudker Transport mechanism of a bacterial homologue of glutamate transporters Nature 462 2009 880 885
-
(2009)
Nature
, vol.462
, pp. 880-885
-
-
Reyes, N.1
Ginter, C.2
Boudker, O.3
-
50
-
-
33748765517
-
Multiple consequences of mutating two conserved beta-bridge forming residues in the translocation cycle of a neuronal glutamate transporter
-
N. Rosental, A. Bendahan, and B.I. Kanner Multiple consequences of mutating two conserved beta-bridge forming residues in the translocation cycle of a neuronal glutamate transporter J. Biol. Chem. 281 2006 27905 27915
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 27905-27915
-
-
Rosental, N.1
Bendahan, A.2
Kanner, B.I.3
-
51
-
-
82355184476
-
A conserved aspartate residue located at the extracellular end of the binding pocket controls cation interactions in brain glutamate transporters
-
N. Rosental, A. Gameiro, C. Grewer, and B.I. Kanner A conserved aspartate residue located at the extracellular end of the binding pocket controls cation interactions in brain glutamate transporters J. Biol. Chem. 286 2011 41381 41390
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 41381-41390
-
-
Rosental, N.1
Gameiro, A.2
Grewer, C.3
Kanner, B.I.4
-
52
-
-
0034688312
-
Glutamate release in severe brain ischaemia is mainly by reversed uptake
-
D.J. Rossi, T. Oshima, and D. Attwell Glutamate release in severe brain ischaemia is mainly by reversed uptake Nature 403 2000 316 321
-
(2000)
Nature
, vol.403
, pp. 316-321
-
-
Rossi, D.J.1
Oshima, T.2
Attwell, D.3
-
53
-
-
2442693929
-
The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway
-
R.M. Ryan, A.D. Mitrovic, and R.J. Vandenberg The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway J. Biol. Chem. 279 2004 20742 20751
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20742-20751
-
-
Ryan, R.M.1
Mitrovic, A.D.2
Vandenberg, R.J.3
-
54
-
-
67650526059
-
Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii
-
R.M. Ryan, E.L. Compton, and J.A. Mindell Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii J. Biol. Chem. 284 2009 17540 17548
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 17540-17548
-
-
Ryan, R.M.1
Compton, E.L.2
Mindell, J.A.3
-
55
-
-
78049427382
-
Modeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologue
-
S.A. Shaikh, and E. Tajkhorshid Modeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologue PLoS Comput. Biol. 6 2010 6
-
(2010)
PLoS Comput. Biol.
, vol.6
, pp. 6
-
-
Shaikh, S.A.1
Tajkhorshid, E.2
-
56
-
-
79551598571
-
The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter
-
J. Shan, J.A. Javitch, L. Shi, and H. Weinstein The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter PLoS ONE 6 2011 e16350
-
(2011)
PLoS ONE
, vol.6
, pp. 16350
-
-
Shan, J.1
Javitch, J.A.2
Shi, L.3
Weinstein, H.4
-
57
-
-
44949086583
-
The mechanism of a neurotransmitter:sodium symporter - Inward release of Na+ and substrate is triggered by substrate in a second binding site
-
L. Shi, M. Quick, Y. Zhao, H. Weinstein, and J.A. Javitch The mechanism of a neurotransmitter:sodium symporter - inward release of Na+ and substrate is triggered by substrate in a second binding site Mol. Cell 30 2008 667 677
-
(2008)
Mol. Cell
, vol.30
, pp. 667-677
-
-
Shi, L.1
Quick, M.2
Zhao, Y.3
Weinstein, H.4
Javitch, J.A.5
-
58
-
-
57649119782
-
Time-resolved mechanism of extracellular gate opening and substrate binding in a glutamate transporter
-
I.H. Shrivastava, J. Jiang, S.G. Amara, and I. Bahar Time-resolved mechanism of extracellular gate opening and substrate binding in a glutamate transporter J. Biol. Chem. 283 2008 28680 28690
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 28680-28690
-
-
Shrivastava, I.H.1
Jiang, J.2
Amara, S.G.3
Bahar, I.4
-
59
-
-
34548178234
-
Antidepressant binding site in a bacterial homologue of neurotransmitter transporters
-
S.K. Singh, A. Yamashita, and E. Gouaux Antidepressant binding site in a bacterial homologue of neurotransmitter transporters Nature 448 2007 952 956
-
(2007)
Nature
, vol.448
, pp. 952-956
-
-
Singh, S.K.1
Yamashita, A.2
Gouaux, E.3
-
60
-
-
58149233796
-
A competitive inhibitor traps LeuT in an open-to-out conformation
-
S.K. Singh, C.L. Piscitelli, A. Yamashita, and E. Gouaux A competitive inhibitor traps LeuT in an open-to-out conformation Science 322 2008 1655 1661
-
(2008)
Science
, vol.322
, pp. 1655-1661
-
-
Singh, S.K.1
Piscitelli, C.L.2
Yamashita, A.3
Gouaux, E.4
-
61
-
-
84861090698
-
Structural intermediates in a model of the substrate translocation path of the bacterial glutamate transporter homologue GltPh
-
S. Stolzenberg, G. Khelashvili, and H. Weinstein Structural intermediates in a model of the substrate translocation path of the bacterial glutamate transporter homologue GltPh J. Phys. Chem. B 116 2012 5372 5383
-
(2012)
J. Phys. Chem. B
, vol.116
, pp. 5372-5383
-
-
Stolzenberg, S.1
Khelashvili, G.2
Weinstein, H.3
-
62
-
-
57049106850
-
Thallium ions can replace both sodium and potassium ions in the glutamate transporter excitatory amino acid carrier 1
-
Z. Tao, A. Gameiro, and C. Grewer Thallium ions can replace both sodium and potassium ions in the glutamate transporter excitatory amino acid carrier 1 Biochemistry 47 2008 12923 12930
-
(2008)
Biochemistry
, vol.47
, pp. 12923-12930
-
-
Tao, Z.1
Gameiro, A.2
Grewer, C.3
-
63
-
-
77952907248
-
Mechanism of cation binding to the glutamate transporter EAAC1 probed with mutation of the conserved amino acid residue T101
-
Z. Tao, N. Rosental, B.I. Kanner, A. Gameiro, J. Mwaura, and C. Grewer Mechanism of cation binding to the glutamate transporter EAAC1 probed with mutation of the conserved amino acid residue T101 J. Biol. Chem. 285 2010 17725 17733
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 17725-17733
-
-
Tao, Z.1
Rosental, N.2
Kanner, B.I.3
Gameiro, A.4
Mwaura, J.5
Grewer, C.6
-
64
-
-
70149086286
-
The equivalent of a thallium binding residue from an archeal homolog controls cation interactions in brain glutamate transporters
-
S. Teichman, S. Qu, and B.I. Kanner The equivalent of a thallium binding residue from an archeal homolog controls cation interactions in brain glutamate transporters Proc. Natl. Acad. Sci. USA 106 2009 14297 14302
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 14297-14302
-
-
Teichman, S.1
Qu, S.2
Kanner, B.I.3
-
65
-
-
84861204243
-
Conserved asparagine residue located in binding pocket controls cation selectivity and substrate interactions in neuronal glutamate transporter
-
S. Teichman, S. Qu, and B.I. Kanner Conserved asparagine residue located in binding pocket controls cation selectivity and substrate interactions in neuronal glutamate transporter J. Biol. Chem. 287 2012 17198 17205
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 17198-17205
-
-
Teichman, S.1
Qu, S.2
Kanner, B.I.3
-
66
-
-
84857992685
-
Crystal structure of an asymmetric trimer of a bacterial glutamate transporter homolog
-
G. Verdon, and O. Boudker Crystal structure of an asymmetric trimer of a bacterial glutamate transporter homolog Nat. Struct. Mol. Biol. 19 2012 355 357
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 355-357
-
-
Verdon, G.1
Boudker, O.2
-
67
-
-
0013875762
-
Inhibition of parallel flux and augmentation of counter flux shown by transport models not involving a mobile carrier
-
G.A. Vidaver Inhibition of parallel flux and augmentation of counter flux shown by transport models not involving a mobile carrier J. Theor. Biol. 10 1966 301 306
-
(1966)
J. Theor. Biol.
, vol.10
, pp. 301-306
-
-
Vidaver, G.A.1
-
68
-
-
0029142729
-
Ion fluxes associated with excitatory amino acid transport
-
J.I. Wadiche, S.G. Amara, and M.P. Kavanaugh Ion fluxes associated with excitatory amino acid transport Neuron 15 1995 721 728
-
(1995)
Neuron
, vol.15
, pp. 721-728
-
-
Wadiche, J.I.1
Amara, S.G.2
Kavanaugh, M.P.3
-
69
-
-
84862790971
-
Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context
-
H. Wang, J. Elferich, and E. Gouaux Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context Nat. Struct. Mol. Biol. 19 2012 212 219
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 212-219
-
-
Wang, H.1
Elferich, J.2
Gouaux, E.3
-
70
-
-
24644470065
-
Crystal structure of a bacterial homologue of Na+/Cl - Dependent neurotransmitter transporters
-
A. Yamashita, S.K. Singh, T. Kawate, Y. Jin, and E. Gouaux Crystal structure of a bacterial homologue of Na+/Cl - dependent neurotransmitter transporters Nature 437 2005 215 223
-
(2005)
Nature
, vol.437
, pp. 215-223
-
-
Yamashita, A.1
Singh, S.K.2
Kawate, T.3
Jin, Y.4
Gouaux, E.5
-
71
-
-
7244254186
-
Structure of a glutamate transporter homologue from Pyrococcus horikoshii
-
D. Yernool, O. Boudker, Y. Jin, and E. Gouaux Structure of a glutamate transporter homologue from Pyrococcus horikoshii Nature 431 2004 811 818
-
(2004)
Nature
, vol.431
, pp. 811-818
-
-
Yernool, D.1
Boudker, O.2
Jin, Y.3
Gouaux, E.4
-
72
-
-
0029860263
-
Flux coupling in a neuronal glutamate transporter
-
N. Zerangue, and M.P. Kavanaugh Flux coupling in a neuronal glutamate transporter Nature 383 1996 634 637
-
(1996)
Nature
, vol.383
, pp. 634-637
-
-
Zerangue, N.1
Kavanaugh, M.P.2
-
73
-
-
79952811744
-
The role of local hydration and hydrogen-bonding dynamics in ion and solute release from ion-coupled secondary transporters
-
C. Zhao, and S.Y. Noskov The role of local hydration and hydrogen-bonding dynamics in ion and solute release from ion-coupled secondary transporters Biochemistry 50 2011 1848 1856
-
(2011)
Biochemistry
, vol.50
, pp. 1848-1856
-
-
Zhao, C.1
Noskov, S.Y.2
-
74
-
-
77952402284
-
Single-molecule dynamics of gating in a neurotransmitter transporter homologue
-
Y. Zhao, D. Terry, L. Shi, H. Weinstein, S.C. Blanchard, and J.A. Javitch Single-molecule dynamics of gating in a neurotransmitter transporter homologue Nature 465 2010 188 193
-
(2010)
Nature
, vol.465
, pp. 188-193
-
-
Zhao, Y.1
Terry, D.2
Shi, L.3
Weinstein, H.4
Blanchard, S.C.5
Javitch, J.A.6
-
75
-
-
79957935490
-
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue
-
Y. Zhao, D.S. Terry, L. Shi, M. Quick, H. Weinstein, S.C. Blanchard, and J.A. Javitch Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue Nature 474 2011 109 113
-
(2011)
Nature
, vol.474
, pp. 109-113
-
-
Zhao, Y.1
Terry, D.S.2
Shi, L.3
Quick, M.4
Weinstein, H.5
Blanchard, S.C.6
Javitch, J.A.7
-
76
-
-
34548684744
-
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake
-
Z. Zhou, J. Zhen, N.K. Karpowich, R.M. Goetz, C.J. Law, M.E. Reith, and D.N. Wang LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake Science 317 2007 1390 1393
-
(2007)
Science
, vol.317
, pp. 1390-1393
-
-
Zhou, Z.1
Zhen, J.2
Karpowich, N.K.3
Goetz, R.M.4
Law, C.J.5
Reith, M.E.6
Wang, D.N.7
-
77
-
-
67349282342
-
Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures
-
Z. Zhou, J. Zhen, N.K. Karpowich, C.J. Law, M.E. Reith, and D.N. Wang Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures Nat. Struct. Mol. Biol. 16 2009 652 657
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 652-657
-
-
Zhou, Z.1
Zhen, J.2
Karpowich, N.K.3
Law, C.J.4
Reith, M.E.5
Wang, D.N.6
|