Mechanism for alternating access in neurotransmitter transporters

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 30, 2008, Pages 10338-10343

  Forrest, Lucy R ^a,c   Zhang, Yuan Wei ^a,b   Jacobs, Miriam T ^b   Gesmonde, Joan ^b   Xie, Li ^a   Honig, Barry H ^a   Rudnick, Gary ^b  

^a Columbia University ^*  (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

Author keywords

Alternating access mechanism; Neurotransmitter:sodium symporters; Serotonin; Structural modeling; Structural repeats

Indexed keywords

CYSTEINE; NEUROTRANSMITTER TRANSPORTER; PROTEIN LEUT; SEROTONIN TRANSPORTER;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOPLASM; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; CYTOPLASM; HELA CELLS; HUMANS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MUTATION; NEUROTRANSMITTER AGENTS; NEUROTRANSMITTER TRANSPORT PROTEINS; RATS; SEROTONIN; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 48349140230     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0804659105     Document Type: Article

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