-
1
-
-
34848821581
-
Extracellular glutamate concentration in hippocampal slice
-
Herman MA, Jahr CE, (2007) Extracellular glutamate concentration in hippocampal slice. J Neurosci 27: 9736-9741.
-
(2007)
J Neurosci
, vol.27
, pp. 9736-9741
-
-
Herman, M.A.1
Jahr, C.E.2
-
3
-
-
0032400828
-
Stoichiometry of the glial glutamate transporter GLT-1 expressed inducibly in a chinese hamster ovary cell line selected for low endogenous Na+-dependent glutamate uptake
-
Levy LM, Warr O, Atwell D, (1998) Stoichiometry of the glial glutamate transporter GLT-1 expressed inducibly in a chinese hamster ovary cell line selected for low endogenous Na+-dependent glutamate uptake. Journal of Neuroscience 18: 9620-9628.
-
(1998)
Journal of Neuroscience
, vol.18
, pp. 9620-9628
-
-
Levy, L.M.1
Warr, O.2
Atwell, D.3
-
4
-
-
0029860263
-
Flux coupling in a neuronal glutamate transporter
-
Zerangue N, Kavanaugh MP, (1996) Flux coupling in a neuronal glutamate transporter. Nature 383: 634-637.
-
(1996)
Nature
, vol.383
, pp. 634-637
-
-
Zerangue, N.1
Kavanaugh, M.P.2
-
5
-
-
0029076899
-
An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
-
Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP, Amara SG, (1995) An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375: 599-603.
-
(1995)
Nature
, vol.375
, pp. 599-603
-
-
Fairman, W.A.1
Vandenberg, R.J.2
Arriza, J.L.3
Kavanaugh, M.P.4
Amara, S.G.5
-
6
-
-
0029023101
-
Constitutive ion fluxes and substrate binding domains of human glutamate transporters
-
Vandenberg RJ, Arriza JL, Amara SG, Kavanaugh MP, (1995) Constitutive ion fluxes and substrate binding domains of human glutamate transporters. Journal of Biological Chemistry 270: 17668-17671.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 17668-17671
-
-
Vandenberg, R.J.1
Arriza, J.L.2
Amara, S.G.3
Kavanaugh, M.P.4
-
7
-
-
0032189020
-
Macroscopic and microscopic properties of a cloned glutamate transporter/chloride channel
-
Wadiche JI, Kavanaugh MP, (1998) Macroscopic and microscopic properties of a cloned glutamate transporter/chloride channel. Journal of Neuroscience 18: 7650-7661.
-
(1998)
Journal of Neuroscience
, vol.18
, pp. 7650-7661
-
-
Wadiche, J.I.1
Kavanaugh, M.P.2
-
8
-
-
7244254186
-
Structure of a glutamate transporter homologue from Pyrococcus horikoshii
-
Yernool D, Boudker O, Jin Y, Gouaux E, (2004) Structure of a glutamate transporter homologue from Pyrococcus horikoshii. Nature 431: 811-818.
-
(2004)
Nature
, vol.431
, pp. 811-818
-
-
Yernool, D.1
Boudker, O.2
Jin, Y.3
Gouaux, E.4
-
9
-
-
33846505059
-
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter
-
Boudker O, Ryan RM, Yernool D, Shimamoto K, Gouaux E, (2007) Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature 445: 387-393.
-
(2007)
Nature
, vol.445
, pp. 387-393
-
-
Boudker, O.1
Ryan, R.M.2
Yernool, D.3
Shimamoto, K.4
Gouaux, E.5
-
10
-
-
34247648737
-
The uncoupled chloride conductance of a bacterial glutamate transporter homolog
-
Ryan RM, Mindell JA, (2007) The uncoupled chloride conductance of a bacterial glutamate transporter homolog. Nat Struct Mol Biol 14: 365-371.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 365-371
-
-
Ryan, R.M.1
Mindell, J.A.2
-
11
-
-
67650526059
-
Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii
-
Ryan RM, Compton EL, Mindell JA, (2009) Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii. J Biol Chem 284: 17540-17548.
-
(2009)
J Biol Chem
, vol.284
, pp. 17540-17548
-
-
Ryan, R.M.1
Compton, E.L.2
Mindell, J.A.3
-
12
-
-
77951680965
-
Na(+):aspartate coupling stoichiometry in the glutamate transporter homologue Glt(Ph)
-
Groeneveld M, Slotboom DJ, (2010) Na(+):aspartate coupling stoichiometry in the glutamate transporter homologue Glt(Ph). Biochemistry 49: 3511-3513.
-
(2010)
Biochemistry
, vol.49
, pp. 3511-3513
-
-
Groeneveld, M.1
Slotboom, D.J.2
-
13
-
-
0034529012
-
Arginine 447 plays a pivotal role in substrate interactions in a neuronal glutamate transporter
-
Bendahan A, Armon A, Madani N, Kavanaugh MP, Kanner BI, (2000) Arginine 447 plays a pivotal role in substrate interactions in a neuronal glutamate transporter. Journal of Biological Chemistry 275: 37436-37442.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 37436-37442
-
-
Bendahan, A.1
Armon, A.2
Madani, N.3
Kavanaugh, M.P.4
Kanner, B.I.5
-
14
-
-
0031028206
-
Mutation of an amino acid residue influencing potassium coupling in the glutamate transporter GLT-1 induces obligate exchange
-
Kavanaugh MP, Bendahan A, Zerangue N, Zhang Y, Kanner BI, (1997) Mutation of an amino acid residue influencing potassium coupling in the glutamate transporter GLT-1 induces obligate exchange. Journal of Biological Chemistry 272: 1703-1708.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 1703-1708
-
-
Kavanaugh, M.P.1
Bendahan, A.2
Zerangue, N.3
Zhang, Y.4
Kanner, B.I.5
-
15
-
-
33748765517
-
Multiple consequences of mutating two conserved beta-bridge forming residues in the translocation cycle of a neuronal glutamate transporter
-
Rosental N, Bendahan A, Kanner BI, (2006) Multiple consequences of mutating two conserved beta-bridge forming residues in the translocation cycle of a neuronal glutamate transporter. J Biol Chem 281: 27905-27915.
-
(2006)
J Biol Chem
, vol.281
, pp. 27905-27915
-
-
Rosental, N.1
Bendahan, A.2
Kanner, B.I.3
-
16
-
-
0033681163
-
A model for the topology of excitatory amino acid transporters determined by the extracellular accessibility of substituted cysteines
-
Seal RP, Leighton BH, Amara SG, (2000) A model for the topology of excitatory amino acid transporters determined by the extracellular accessibility of substituted cysteines. Neuron 25: 695-706.
-
(2000)
Neuron
, vol.25
, pp. 695-706
-
-
Seal, R.P.1
Leighton, B.H.2
Amara, S.G.3
-
17
-
-
2442693929
-
The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway
-
Ryan RM, Mitrovic AD, Vandenberg RJ, (2004) The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway. J Biol Chem 279: 20742-20751.
-
(2004)
J Biol Chem
, vol.279
, pp. 20742-20751
-
-
Ryan, R.M.1
Mitrovic, A.D.2
Vandenberg, R.J.3
-
19
-
-
77952907248
-
Mechanism of cation binding to the glutamate transporter EAAC1 probed with mutation of the conserved amino acid residue Thr101
-
Tao Z, Rosental N, Kanner BI, Gameiro A, Mwaura J, et al. (2010) Mechanism of cation binding to the glutamate transporter EAAC1 probed with mutation of the conserved amino acid residue Thr101. J Biol Chem 285: 17725-17733.
-
(2010)
J Biol Chem
, vol.285
, pp. 17725-17733
-
-
Tao, Z.1
Rosental, N.2
Kanner, B.I.3
Gameiro, A.4
Mwaura, J.5
-
20
-
-
77956527543
-
Identification of the third Na+ site and the sequence of extracellular binding events in the glutamate transporter
-
Huang Z, Tajkhorshid E, (2010) Identification of the third Na+ site and the sequence of extracellular binding events in the glutamate transporter. Biophys J 99: 1416-1425.
-
(2010)
Biophys J
, vol.99
, pp. 1416-1425
-
-
Huang, Z.1
Tajkhorshid, E.2
-
21
-
-
77956362466
-
Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model
-
Larsson HP, Wang X, Lev B, Baconguis I, Caplan DA, et al. (2010) Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model. Proc Natl Acad Sci U S A 107: 13912-13917.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 13912-13917
-
-
Larsson, H.P.1
Wang, X.2
Lev, B.3
Baconguis, I.4
Caplan, D.A.5
-
22
-
-
33744518437
-
Neutralization of the aspartic acid residue Asp-367, but not Asp-454, inhibits binding of Na+ to the glutamate-free form and cycling of the glutamate transporter EAAC1
-
Tao Z, Zhang Z, Grewer C, (2006) Neutralization of the aspartic acid residue Asp-367, but not Asp-454, inhibits binding of Na+ to the glutamate-free form and cycling of the glutamate transporter EAAC1. Journal of Biological Chemistry 281: 10263-10272.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 10263-10272
-
-
Tao, Z.1
Zhang, Z.2
Grewer, C.3
-
23
-
-
51649088013
-
Dynamics of the extracellular gate and ion-substrate coupling in the glutamate transporter
-
Huang Z, Tajkhorshid E, (2008) Dynamics of the extracellular gate and ion-substrate coupling in the glutamate transporter. Biophys J 95: 2292-2300.
-
(2008)
Biophys J
, vol.95
, pp. 2292-2300
-
-
Huang, Z.1
Tajkhorshid, E.2
-
24
-
-
57649119782
-
Time-resolved mechanism of extracellular gate opening and substrate binding in a glutamate transporter
-
Shrivastava IH, Jiang J, Amara SG, Bahar I, (2008) Time-resolved mechanism of extracellular gate opening and substrate binding in a glutamate transporter. J Biol Chem 283: 28680-28690.
-
(2008)
J Biol Chem
, vol.283
, pp. 28680-28690
-
-
Shrivastava, I.H.1
Jiang, J.2
Amara, S.G.3
Bahar, I.4
-
25
-
-
0032486463
-
Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue
-
Zarbiv R, Grunewald M, Kavanaugh MP, Kanner BI, (1998) Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue. Journal of Biological Chemistry 273: 14231-14237.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 14231-14237
-
-
Zarbiv, R.1
Grunewald, M.2
Kavanaugh, M.P.3
Kanner, B.I.4
-
26
-
-
72449164409
-
Transport mechanism of a bacterial homologue of glutamate transporters
-
Reyes N, Ginter C, Boudker O, (2009) Transport mechanism of a bacterial homologue of glutamate transporters. Nature 462: 880-885.
-
(2009)
Nature
, vol.462
, pp. 880-885
-
-
Reyes, N.1
Ginter, C.2
Boudker, O.3
-
27
-
-
17844367330
-
Structure of the rotor ring of F-Type Na+-ATPase from Ilyobacter tartaricus
-
Meier T, Polzer P, Diederichs K, Welte W, Dimroth P, (2005) Structure of the rotor ring of F-Type Na+-ATPase from Ilyobacter tartaricus. Science 308: 659-662.
-
(2005)
Science
, vol.308
, pp. 659-662
-
-
Meier, T.1
Polzer, P.2
Diederichs, K.3
Welte, W.4
Dimroth, P.5
-
29
-
-
27344436659
-
Scalable molecular dynamics with NAMD
-
Phillips JC, Braun R, Wang W, Gumbart J, Tajkhorshid E, et al. (2005) Scalable molecular dynamics with NAMD. J Comput Chem 26: 1781-1802.
-
(2005)
J Comput Chem
, vol.26
, pp. 1781-1802
-
-
Phillips, J.C.1
Braun, R.2
Wang, W.3
Gumbart, J.4
Tajkhorshid, E.5
-
30
-
-
0041784950
-
All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins
-
MacKerell ADJ, Bashford D, Bellott M, Dunbrack RL Jr, Evanseck JD, Field MJ, Fischer S, Gao J, Guo H, Ha S, Joseph-McCarthy D, Kuchnir L, Kuczera K, Lau FTK, Mattos C, Michnick S, Ngo T, Nguyen DT, Prodhom B, Reiher WE III, Roux B, Schlenkrich M, Smith JC, Stote R, Straub J, Watanabe M, Wiórkiewicz-Kuczera J, Yin D, Karplus M, (1998) All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins. The Journal of Physical Chemistry B 102: 3586-3616.
-
(1998)
The Journal of Physical Chemistry B
, vol.102
, pp. 3586-3616
-
-
MacKerell, A.D.J.1
Bashford, D.2
Bellott, M.3
Dunbrack Jr., R.L.4
Evanseck, J.D.5
Field, M.J.6
Fischer, S.7
Gao, J.8
Guo, H.9
Ha, S.10
Joseph-McCarthy, D.11
Kuchnir, L.12
Kuczera, K.13
Lau, F.T.K.14
Mattos, C.15
Michnick, S.16
Ngo, T.17
Nguyen, D.T.18
Prodhom, B.19
Reiher III., W.E.20
Roux, B.21
Schlenkrich, M.22
Smith, J.C.23
Stote, R.24
Straub, J.25
Watanabe, M.26
Wiórkiewicz-Kuczera, J.27
Yin, D.28
Karplus, M.29
more..
-
31
-
-
3142714765
-
Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations
-
Mackerell AD Jr, Feig M, Brooks CL 3rd, (2004) Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations. J Comput Chem 25: 1400-1415.
-
(2004)
J Comput Chem
, vol.25
, pp. 1400-1415
-
-
Mackerell Jr., A.D.1
Feig, M.2
Brooks, C.L.3
-
32
-
-
0141682863
-
Absolute binding free energies: A quantitative approach for their calculation
-
Boresch S, Tettinger F, Leitgeb M, Karplus M, (2003) Absolute binding free energies: A quantitative approach for their calculation. Journal of Physical Chemistry B 107: 9535-9551.
-
(2003)
Journal of Physical Chemistry B
, vol.107
, pp. 9535-9551
-
-
Boresch, S.1
Tettinger, F.2
Leitgeb, M.3
Karplus, M.4
-
33
-
-
0000127140
-
Method for Estimating the Configurational Entropy of Macromolecules
-
Karplus M, Kushick JN, (1981) Method for Estimating the Configurational Entropy of Macromolecules. Macromolecules 14: 325-332.
-
(1981)
Macromolecules
, vol.14
, pp. 325-332
-
-
Karplus, M.1
Kushick, J.N.2
-
34
-
-
33744944511
-
Energetics of ion permeation, rejection, binding, and block in gramicidin A from free energy simulations
-
Bastug T, Kuyucak S, (2006) Energetics of ion permeation, rejection, binding, and block in gramicidin A from free energy simulations. Biophys J 90: 3941-3950.
-
(2006)
Biophys J
, vol.90
, pp. 3941-3950
-
-
Bastug, T.1
Kuyucak, S.2
-
35
-
-
0024578173
-
Free energy via molecular simulation: applications to chemical and biomolecular systems
-
Beveridge DL, DiCapua FM, (1989) Free energy via molecular simulation: applications to chemical and biomolecular systems. Annu Rev Biophys Biophys Chem 18: 431-492.
-
(1989)
Annu Rev Biophys Biophys Chem
, vol.18
, pp. 431-492
-
-
Beveridge, D.L.1
DiCapua, F.M.2
-
37
-
-
0029869003
-
Purification and reconstitution of the glutamate carrier GltT of the thermophillic bacterium Bacillus stearothermophillus
-
Gaillard I, Slotboom D, Knol J, Lolkema JS, Konings WN, (1996) Purification and reconstitution of the glutamate carrier GltT of the thermophillic bacterium Bacillus stearothermophillus. Biochemistry 35: 6150-6156.
-
(1996)
Biochemistry
, vol.35
, pp. 6150-6156
-
-
Gaillard, I.1
Slotboom, D.2
Knol, J.3
Lolkema, J.S.4
Konings, W.N.5
-
38
-
-
0031953098
-
Serine-O-sulphate transport by the human glutamate transporter, EAAT2
-
Vandenberg RJ, Mitrovic AD, Johnston GA, (1998) Serine-O-sulphate transport by the human glutamate transporter, EAAT2. British Journal of Pharmacology 123: 1593-1600.
-
(1998)
British Journal of Pharmacology
, vol.123
, pp. 1593-1600
-
-
Vandenberg, R.J.1
Mitrovic, A.D.2
Johnston, G.A.3
-
39
-
-
84858142733
-
-
The PyMOL Molecular Graphics System, Version 1.3r1
-
Schrodinger LLC, (2010) The PyMOL Molecular Graphics System, Version 1.3r1.
-
(2010)
-
-
Schrodinger, L.L.C.1
-
40
-
-
36448991500
-
Clustal W and clustal X version 2.0
-
Higgins DG, Larkin MA, Blackshields G, Brown NP, Chenna R, et al. (2007) Clustal W and clustal X version 2.0. Bioinformatics 23: 2947-2948.
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Higgins, D.G.1
Larkin, M.A.2
Blackshields, G.3
Brown, N.P.4
Chenna, R.5
|