-
1
-
-
0030812843
-
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1
-
DOI 10.1126/science.276.5319.1699
-
K. Tanaka, and K. Watase K. Wada Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1 Science 276 1997 1699 1702 (Pubitemid 27421977)
-
(1997)
Science
, vol.276
, Issue.5319
, pp. 1699-1702
-
-
Tanaka, K.1
Watase, K.2
Manabe, T.3
Yamada, K.4
Watanabe, M.5
Takahashi, K.6
Iwama, H.7
Nishikawa, T.8
Ichihara, N.9
Kikuchi, T.10
Okuyama, S.11
Kawashima, N.12
Hori, S.13
Takimoto, M.14
Wada, K.15
-
2
-
-
0029860263
-
Flux coupling in a neuronal glutamate transporter
-
DOI 10.1038/383634a0
-
N. Zerangue, and M.P. Kavanaugh Flux coupling in a neuronal glutamate transporter Nature 383 1996 634 637 (Pubitemid 26347587)
-
(1996)
Nature
, vol.383
, Issue.6601
, pp. 634-637
-
-
Zerangue, N.1
Kavanaugh, M.P.2
-
3
-
-
0035993231
-
Excitatory amino acid transporters: Keeping up with glutamate
-
S.G. Amara, and A.C. Fontana Excitatory amino acid transporters: keeping up with glutamate Neurochem. Int. 41 2002 313 318
-
(2002)
Neurochem. Int.
, vol.41
, pp. 313-318
-
-
Amara, S.G.1
Fontana, A.C.2
-
4
-
-
77951680965
-
Na(+):aspartate coupling stoichiometry in the glutamate transporter homologue Glt(Ph)
-
M. Groeneveld, and D.-J. Slotboom Na(+):aspartate coupling stoichiometry in the glutamate transporter homologue Glt(Ph) Biochemistry 49 2010 3511 3513
-
(2010)
Biochemistry
, vol.49
, pp. 3511-3513
-
-
Groeneveld, M.1
Slotboom, D.-J.2
-
5
-
-
7244254186
-
Structure of a glutamate transporter homologue from Pyrococcus horikoshii
-
DOI 10.1038/nature03018
-
D. Yernool, and O. Boudker E. Gouaux Structure of a glutamate transporter homologue from Pyrococcus horikoshii Nature 431 2004 811 818 (Pubitemid 39434071)
-
(2004)
Nature
, vol.431
, Issue.7010
, pp. 811-818
-
-
Yernool, D.1
Boudker, O.2
Jin, Y.3
Gouaux, E.4
-
6
-
-
33846505059
-
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter
-
DOI 10.1038/nature05455, PII NATURE05455
-
O. Boudker, and R.M. Ryan E. Gouaux Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter Nature 445 2007 387 393 (Pubitemid 46160902)
-
(2007)
Nature
, vol.445
, Issue.7126
, pp. 387-393
-
-
Boudker, O.1
Ryan, R.M.2
Yernool, D.3
Shimamoto, K.4
Gouaux, E.5
-
7
-
-
72449164409
-
Transport mechanism of a bacterial homologue of glutamate transporters
-
N. Reyes, C. Ginter, and O. Boudker Transport mechanism of a bacterial homologue of glutamate transporters Nature 462 2009 880 885
-
(2009)
Nature
, vol.462
, pp. 880-885
-
-
Reyes, N.1
Ginter, C.2
Boudker, O.3
-
8
-
-
0037040231
-
Proximity of two oppositely oriented reentrant loops in the glutamate transporter GLT-1 identified by paired cysteine mutagenesis
-
DOI 10.1074/jbc.M107735200
-
L. Brocke, and A. Bendahan B.I. Kanner Proximity of two oppositely oriented reentrant loops in the glutamate transporter GLT-1 identified by paired cysteine mutagenesis J. Biol. Chem. 277 2002 3985 3992 (Pubitemid 34968653)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.6
, pp. 3985-3992
-
-
Brocke, L.1
Bendahan, A.2
Grunewald, M.3
Kanner, B.I.4
-
9
-
-
33749558576
-
Structural rearrangements at the translocation pore of the human glutamate transporter, EAAT1
-
DOI 10.1074/jbc.M604991200
-
B.H. Leighton, and R.P. Seal S.G. Amara Structural rearrangements at the translocation pore of the human glutamate transporter, EAAT1 J. Biol. Chem. 281 2006 29788 29796 (Pubitemid 44536988)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.40
, pp. 29788-29796
-
-
Leighton, B.H.1
Seal, R.P.2
Watts, S.D.3
Skyba, M.O.4
Amara, S.G.5
-
10
-
-
55549111238
-
Substrates and non-transportable analogues induce structural rearrangements at the extracellular entrance of the glial glutamate transporter GLT-1/EAAT2
-
S. Qu, and B.I. Kanner Substrates and non-transportable analogues induce structural rearrangements at the extracellular entrance of the glial glutamate transporter GLT-1/EAAT2 J. Biol. Chem. 283 2008 26391 26400
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26391-26400
-
-
Qu, S.1
Kanner, B.I.2
-
12
-
-
57649119782
-
Time-resolved mechanism of extracellular gate opening and substrate binding in a glutamate transporter
-
I.H. Shrivastava, and J. Jiang I. Bahar Time-resolved mechanism of extracellular gate opening and substrate binding in a glutamate transporter J. Biol. Chem. 283 2008 28680 28690
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 28680-28690
-
-
Shrivastava, I.H.1
Jiang, J.2
Bahar, I.3
-
13
-
-
62449268980
-
Molecular simulations elucidate the substrate translocation pathway in a glutamate transporter
-
Y. Gu, and I.H. Shrivastava I. Bahar Molecular simulations elucidate the substrate translocation pathway in a glutamate transporter Proc. Natl. Acad. Sci. USA 106 2009 2589 2594
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 2589-2594
-
-
Gu, Y.1
Shrivastava, I.H.2
Bahar, I.3
-
14
-
-
73949133608
-
Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats
-
T.J. Crisman, and S. Qu L.R. Forrest Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats Proc. Natl. Acad. Sci. USA 106 2009 20752 20757
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20752-20757
-
-
Crisman, T.J.1
Qu, S.2
Forrest, L.R.3
-
15
-
-
0001398337
-
A general theory of membrane transport from studies of bacteria
-
P. Mitchell A general theory of membrane transport from studies of bacteria Nature 180 1957 134 136
-
(1957)
Nature
, vol.180
, pp. 134-136
-
-
Mitchell, P.1
-
16
-
-
77956527543
-
+ site and the sequence of extracellular binding events in the glutamate transporter
-
+ site and the sequence of extracellular binding events in the glutamate transporter Biophys. J. 99 2010 1416 1425
-
(2010)
Biophys. J.
, vol.99
, pp. 1416-1425
-
-
Huang, Z.1
Tajkhorshid, E.2
-
17
-
-
79951619800
-
The mechanism of substrate release by the aspartate transporter GltPh: Insights from simulations
-
J. DeChancie, I.H. Shrivastava, and I. Bahar The mechanism of substrate release by the aspartate transporter GltPh: insights from simulations Mol. Biosyst. 7 2011 832 842
-
(2011)
Mol. Biosyst.
, vol.7
, pp. 832-842
-
-
Dechancie, J.1
Shrivastava, I.H.2
Bahar, I.3
-
18
-
-
0034663710
-
Dynamics of proteins predicted by molecular simulations and analytical approaches: Application to α-amylase inhibitor
-
DOI 10.1002/1097-0134(2000 0815)40:3<512::AID-PRO T180>3.0.CO;2-M
-
P. Doruker, A.R. Atilgan, and I. Bahar Dynamics of proteins predicted by molecular dynamics simulations and analytical approaches: application to α-amylase inhibitor Proteins 40 2000 512 524 (Pubitemid 30624460)
-
(2000)
Proteins: Structure, Function and Genetics
, vol.40
, Issue.3
, pp. 512-524
-
-
Doruker, P.1
Atilgan, A.R.2
Bahar, I.3
-
19
-
-
0035132230
-
Anisotropy of fluctuation dynamics of proteins with an elastic network model
-
A.R. Atilgan, and S.R. Durell I. Bahar Anisotropy of fluctuation dynamics of proteins with an elastic network model Biophys. J. 80 2001 505 515
-
(2001)
Biophys. J.
, vol.80
, pp. 505-515
-
-
Atilgan, A.R.1
Durell, S.R.2
Bahar, I.3
-
20
-
-
77949634796
-
Normal mode analysis of biomolecular structures: Functional mechanisms of membrane proteins
-
I. Bahar, and T.R. Lezon I.H. Shrivastava Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins Chem. Rev. 110 2010 1463 1497
-
(2010)
Chem. Rev.
, vol.110
, pp. 1463-1497
-
-
Bahar, I.1
Lezon, T.R.2
Shrivastava, I.H.3
-
21
-
-
33744926664
-
Common mechanism of pore opening shared by five different potassium channels
-
DOI 10.1529/biophysj.105.080093
-
I.H. Shrivastava, and I. Bahar Common mechanism of pore opening shared by five different potassium channels Biophys. J. 90 2006 3929 3940 (Pubitemid 43846111)
-
(2006)
Biophysical Journal
, vol.90
, Issue.11
, pp. 3929-3940
-
-
Shrivastava, I.H.1
Bahar, I.2
-
22
-
-
47749099638
-
Mechanism of signal propagation upon retinal isomerization: Insights from molecular dynamics simulations of rhodopsin restrained by normal modes
-
B. Isin, and K. Schulten I. Bahar Mechanism of signal propagation upon retinal isomerization: insights from molecular dynamics simulations of rhodopsin restrained by normal modes Biophys. J. 95 2008 789 803
-
(2008)
Biophys. J.
, vol.95
, pp. 789-803
-
-
Isin, B.1
Schulten, K.2
Bahar, I.3
-
23
-
-
70349661903
-
Global motions of the nuclear pore complex: Insights from elastic network models
-
T.R. Lezon, A. Sali, and I. Bahar Global motions of the nuclear pore complex: insights from elastic network models PLoS Comput. Biol. 5 2009 e1000496
-
(2009)
PLoS Comput. Biol.
, vol.5
, pp. 1000496
-
-
Lezon, T.R.1
Sali, A.2
Bahar, I.3
-
25
-
-
33644861214
-
OPM: Orientations of proteins in membranes database
-
DOI 10.1093/bioinformatics/btk023
-
M.A. Lomize, and A.L. Lomize H.I. Mosberg OPM: orientations of proteins in membranes database Bioinformatics 22 2006 623 625 (Pubitemid 43372827)
-
(2006)
Bioinformatics
, vol.22
, Issue.5
, pp. 623-625
-
-
Lomize, M.A.1
Lomize, A.L.2
Pogozheva, I.D.3
Mosberg, H.I.4
-
26
-
-
0033028551
-
Lipid composition and the lateral pressure profile in bilayers
-
R.S. Cantor Lipid composition and the lateral pressure profile in bilayers Biophys. J. 76 1999 2625 2639 (Pubitemid 29264622)
-
(1999)
Biophysical Journal
, vol.76
, Issue.5
, pp. 2625-2639
-
-
Cantor, R.S.1
-
27
-
-
0032857624
-
The influence of membrane lateral pressures on simple geometric models of protein conformational equilibria
-
DOI 10.1016/S0009-3084(99)00054-7, PII S0009308499000547
-
R.S. Cantor The influence of membrane lateral pressures on simple geometric models of protein conformational equilibria Chem. Phys. Lipids 101 1999 45 56 (Pubitemid 29385550)
-
(1999)
Chemistry and Physics of Lipids
, vol.101
, Issue.1
, pp. 45-56
-
-
Cantor, R.S.1
-
29
-
-
0036840202
-
2+-ATPase
-
G. Li, and Q. Cui A coarse-grained normal mode approach for macromolecules: an efficient implementation and application to Ca(2+)-ATPase Biophys. J. 83 2002 2457 2474 (Pubitemid 35265740)
-
(2002)
Biophysical Journal
, vol.83
, Issue.5
, pp. 2457-2474
-
-
Li, G.1
Cui, Q.2
-
30
-
-
0020997912
-
Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features
-
W. Kabsch, and C. Sander Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features Biopolymers 22 1983 2577 2637
-
(1983)
Biopolymers
, vol.22
, pp. 2577-2637
-
-
Kabsch, W.1
Sander, C.2
-
32
-
-
28844456158
-
Allostery in a coarse-grained model of protein dynamics
-
D. Ming, and M.E. Wall Allostery in a coarse-grained model of protein dynamics Phys. Rev. Lett. 95 2005 198103
-
(2005)
Phys. Rev. Lett.
, vol.95
, pp. 198103
-
-
Ming, D.1
Wall, M.E.2
-
33
-
-
33749521415
-
Optimization and evaluation of a coarse-grained model of protein motion using x-ray crystal data
-
DOI 10.1529/biophysj.106.085894
-
D.A. Kondrashov, Q. Cui, and G.N. Phillips Jr. Optimization and evaluation of a coarse-grained model of protein motion using x-ray crystal data Biophys. J. 91 2006 2760 2767 (Pubitemid 44526467)
-
(2006)
Biophysical Journal
, vol.91
, Issue.8
, pp. 2760-2767
-
-
Kondrashov, D.A.1
Cui, Q.2
Phillips Jr., G.N.3
-
34
-
-
23244442698
-
Probing the local dynamics of nucleotide-binding pocket coupled to the global dynamics: Myosin versus kinesin
-
DOI 10.1529/biophysj.105.063305
-
W.J. Zheng, and B.R. Brooks Probing the local dynamics of nucleotide-binding pocket coupled to the global dynamics: myosin versus kinesin Biophys. J. 89 2005 167 178 (Pubitemid 41098273)
-
(2005)
Biophysical Journal
, vol.89
, Issue.1
, pp. 167-178
-
-
Zheng, W.1
Brooks, B.R.2
-
36
-
-
24344507684
-
Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other
-
DOI 10.1021/bi050987n
-
C. Grewer, and P. Balani T. Rauen Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other Biochemistry 44 2005 11913 11923 (Pubitemid 41262726)
-
(2005)
Biochemistry
, vol.44
, Issue.35
, pp. 11913-11923
-
-
Grewer, C.1
Balani, P.2
Weidenfeller, C.3
Bartusel, T.4
Tao, Z.5
Rauen, T.6
-
37
-
-
14044263640
-
Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters
-
DOI 10.1523/JNEUROSCI.4138-04.2005
-
H.P. Koch, and H.P. Larsson Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters J. Neurosci. 25 2005 1730 1736 (Pubitemid 40279278)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.7
, pp. 1730-1736
-
-
Koch, H.P.1
Larsson, H.P.2
-
38
-
-
34548148634
-
Rigidity of the Subunit Interfaces of the Trimeric Glutamate Transporter GltT During Translocation
-
DOI 10.1016/j.jmb.2007.06.067, PII S0022283607008741
-
M. Groeneveld, and D.J. Slotboom Rigidity of the subunit interfaces of the trimeric glutamate transporter GltT during translocation J. Mol. Biol. 372 2007 565 570 (Pubitemid 47313480)
-
(2007)
Journal of Molecular Biology
, vol.372
, Issue.3
, pp. 565-570
-
-
Groeneveld, M.1
Slotboom, D.-J.2
-
39
-
-
33947318986
-
The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits
-
DOI 10.1523/JNEUROSCI.0118-07.2007
-
H.P. Koch, R.L. Brown, and H.P. Larsson The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits J. Neurosci. 27 2007 2943 2947 (Pubitemid 46438962)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.11
, pp. 2943-2947
-
-
Koch, H.P.1
Brown, R.L.2
Larsson, H.P.3
-
40
-
-
33947308773
-
The glutamate and chloride permeation pathways are colocalized in individual neuronal glutamate transporter subunits
-
DOI 10.1523/JNEUROSCI.4851-06.2007
-
G.P. Leary, and E.F. Stone M.P. Kavanaugh The glutamate and chloride permeation pathways are colocalized in individual neuronal glutamate transporter subunits J. Neurosci. 27 2007 2938 2942 (Pubitemid 46438969)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.11
, pp. 2938-2942
-
-
Leary, G.P.1
Stone, E.F.2
Holley, D.C.3
Kavanaugh, M.P.4
-
41
-
-
73649090059
-
Random matrix approach to collective behavior and bulk universality in protein dynamics
-
R. Potestio, F. Caccioli, and P. Vivo Random matrix approach to collective behavior and bulk universality in protein dynamics Phys. Rev. Lett. 103 2009 268101
-
(2009)
Phys. Rev. Lett.
, vol.103
, pp. 268101
-
-
Potestio, R.1
Caccioli, F.2
Vivo, P.3
-
42
-
-
77953050209
-
On the functional significance of soft modes predicted by coarse-grained models for membrane proteins
-
I. Bahar On the functional significance of soft modes predicted by coarse-grained models for membrane proteins J. Gen. Physiol. 135 2010 563 573
-
(2010)
J. Gen. Physiol.
, vol.135
, pp. 563-573
-
-
Bahar, I.1
-
44
-
-
22244438519
-
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism
-
DOI 10.1529/biophysj.104.050229
-
A. Taly, and M. Delarue J.P. Changeux Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism Biophys. J. 88 2005 3954 3965 (Pubitemid 40991108)
-
(2005)
Biophysical Journal
, vol.88
, Issue.6
, pp. 3954-3965
-
-
Taly, A.1
Delarue, M.2
Grutter, T.3
Nilges, M.4
Le Novere, N.5
Corringer, P.-J.6
Changeux, J.-P.7
-
45
-
-
33746794687
-
The Open State Gating Mechanism of Gramicidin A Requires Relative Opposed Monomer Rotation and Simultaneous Lateral Displacement
-
DOI 10.1016/j.str.2006.06.007, PII S0969212606002905
-
G.V. Miloshevsky, and P.C. Jordan The open state gating mechanism of gramicidin a requires relative opposed monomer rotation and simultaneous lateral displacement Structure 14 2006 1241 1249 (Pubitemid 44176369)
-
(2006)
Structure
, vol.14
, Issue.8
, pp. 1241-1249
-
-
Miloshevsky, G.V.1
Jordan, P.C.2
-
46
-
-
80053084303
-
Large collective motions regulate the functional properties of glutamate transporter trimers
-
J. Jiang, and I.H. Shrivastava S.G. Amara Large collective motions regulate the functional properties of glutamate transporter trimers Proc. Natl. Acad. Sci. USA 108 2011 15141 15146
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 15141-15146
-
-
Jiang, J.1
Shrivastava, I.H.2
Amara, S.G.3
|