The role of cation binding in determining substrate selectivity of glutamate transporters

Journal of Biological Chemistry

Volumn 284, Issue 7, 2009, Pages 4510-4515

  Shiwei, Huang ^a   Ryan, Renae M ^a   Vandenberg, Robert J ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARCHAEAL; CATION BINDING; COUNTERTRANSPORT; DICARBOXYLIC ACID; EXCITATORY AMINO ACIDS; GLUTAMATE TRANSPORTERS; MOLECULAR BASIS; SUBSTRATE SELECTIVITY;

AMINES; AMINO ACIDS; BINDING ENERGY; BINDING SITES; CRYSTAL STRUCTURE; ORGANIC ACIDS; POSITIVE IONS; SULFUR COMPOUNDS;

SUBSTRATES;

3,4 METHANOPYRROLIDINE DICARBOXYLIC ACID; 4 METHYLGLUTAMIC ACID; CATION; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; GLUTAMATE TRANSPORTER; GLUTAMIC ACID DERIVATIVE; GLYCINE; LITHIUM ION; SERINE; SODIUM ION; UNCLASSIFIED DRUG; DRUG DERIVATIVE; GLUTAMIC ACID; LITHIUM; MONOVALENT CATION; SLC1A2 PROTEIN, HUMAN; SLC1A3 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING KINETICS; BINDING SITE; CATION TRANSPORT; CONTROLLED STUDY; ION CURRENT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; XENOPUS LAEVIS; ANIMAL; DRUG EFFECT; ENZYME SPECIFICITY; GENETICS; HUMAN; ION TRANSPORT; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ARCHAEA;

ANIMALS; BINDING SITES; CATIONS, MONOVALENT; EXCITATORY AMINO ACID TRANSPORTER 1; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMIC ACID; HUMANS; ION TRANSPORT; LITHIUM; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; XENOPUS LAEVIS;

EID: 63249114685     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808495200     Document Type: Article

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