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Volumn 55, Issue 1-3, 2013, Pages 10-21

Linking complement and anti-dsDNA antibodies in the pathogenesis of systemic lupus erythematosus

Author keywords

Anti dsDNA antibodies; Autoantibodies; Clearance; Complement; SLE

Indexed keywords

AUTOANTIBODY; COMPLEMENT; COMPLEMENT RECEPTOR; DOUBLE STRANDED DNA; DOUBLE STRANDED DNA ANTIBODY;

EID: 84876739268     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-012-8345-z     Document Type: Article
Times cited : (68)

References (144)
  • 1
    • 40049093765 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • 18305268 1:CAS:528:DC%2BD1cXisF2mtbo%3D
    • Rahman A, Isenberg DA. Systemic lupus erythematosus. New Engl J Med. 2008;358(9):929-39.
    • (2008) New Engl J Med , vol.358 , Issue.9 , pp. 929-939
    • Rahman, A.1    Isenberg, D.A.2
  • 2
    • 78650221829 scopus 로고    scopus 로고
    • Moving towards a cure: Blocking pathogenic antibodies in systemic lupus erythematosus
    • 21158976 1:CAS:528:DC%2BC3MXhsFKms70%3D
    • Diamond B, Bloom O, Al Abed Y, Kowal C, Huerta PT, Volpe BT. Moving towards a cure: blocking pathogenic antibodies in systemic lupus erythematosus. J Intern Med. 2011;269(1):36-44.
    • (2011) J Intern Med , vol.269 , Issue.1 , pp. 36-44
    • Diamond, B.1    Bloom, O.2    Al Abed, Y.3    Kowal, C.4    Huerta, P.T.5    Volpe, B.T.6
  • 3
    • 0021885638 scopus 로고
    • Detection of cross-reactive anti-DNA antibody idiotypes in the serum of systemic lupus erythematosus patients and of their relatives
    • 1:STN:280:DyaL2MzgslWnsA%3D%3D
    • Isenberg DA, Shoenfeld Y, Walport M, Mackworth-Young C, Dudeney C, Todd-Pokropek A, et al. Detection of cross-reactive anti-DNA antibody idiotypes in the serum of systemic lupus erythematosus patients and of their relatives. Arthr Rheum. 1985;28(9):999-1007.
    • (1985) Arthr Rheum , vol.28 , Issue.9 , pp. 999-1007
    • Isenberg, D.A.1    Shoenfeld, Y.2    Walport, M.3    Mackworth-Young, C.4    Dudeney, C.5    Todd-Pokropek, A.6
  • 4
    • 0001510054 scopus 로고
    • A serum factor in lupus erythematosus with affinity for tissue nuclei
    • 13460368 1:STN:280:DyaG1c%2FgtlShsQ%3D%3D
    • Holborow EJ, Weir DM, Johnson GD. A serum factor in lupus erythematosus with affinity for tissue nuclei. BMJ. 1957;2(5047):732-4.
    • (1957) BMJ , vol.2 , Issue.5047 , pp. 732-734
    • Holborow, E.J.1    Weir, D.M.2    Johnson, G.D.3
  • 5
    • 0014135030 scopus 로고
    • Immunological studies concerning the nephritis of systemic lupus erythematosus
    • 4168098 1:STN:280:DyaF1c%2FhslCktg%3D%3D
    • Koffler D, Schur PH, Kunkel HG. Immunological studies concerning the nephritis of systemic lupus erythematosus. J Exp Med. 1967;126(4):607-24.
    • (1967) J Exp Med , vol.126 , Issue.4 , pp. 607-624
    • Koffler, D.1    Schur, P.H.2    Kunkel, H.G.3
  • 6
    • 0142009533 scopus 로고    scopus 로고
    • Development of autoantibodies before the clinical onset of systemic lupus erythematosus
    • 14561795 1:CAS:528:DC%2BD3sXotFGhsrY%3D
    • Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. New Engl J Med. 2003;349(16):1526-33.
    • (2003) New Engl J Med , vol.349 , Issue.16 , pp. 1526-1533
    • Arbuckle, M.R.1    McClain, M.T.2    Rubertone, M.V.3    Scofield, R.H.4    Dennis, G.J.5    James, J.A.6
  • 7
    • 20244383590 scopus 로고    scopus 로고
    • Relationship between anti-double-stranded DNA antibodies and exacerbation of renal disease in patients with systemic lupus erythematosus
    • 1:CAS:528:DC%2BD2MXktFCkt7Y%3D
    • Linnik MD, Hu JZ, Heilbrunn KR, Strand V, Hurley FL, Joh T, et al. Relationship between anti-double-stranded DNA antibodies and exacerbation of renal disease in patients with systemic lupus erythematosus. Arthr Rheum. 2005;52(4):1129-37.
    • (2005) Arthr Rheum , vol.52 , Issue.4 , pp. 1129-1137
    • Linnik, M.D.1    Hu, J.Z.2    Heilbrunn, K.R.3    Strand, V.4    Hurley, F.L.5    Joh, T.6
  • 8
    • 0025374697 scopus 로고
    • Measurement of increases in anti-double-stranded DNA antibody levels as a predictor of disease exacerbation in systemic lupus erythematosus
    • Ter Borg EJ, Horst G, Hummel EJ, Limburg PC, Kallenberg CGM. Measurement of increases in anti-double-stranded DNA antibody levels as a predictor of disease exacerbation in systemic lupus erythematosus. Arthr Rheum. 1990;33(5):634-43.
    • (1990) Arthr Rheum , vol.33 , Issue.5 , pp. 634-643
    • Ter Borg, E.J.1    Horst, G.2    Hummel, E.J.3    Limburg, P.C.4    Kallenberg, C.G.M.5
  • 9
    • 33845477908 scopus 로고    scopus 로고
    • Association of antinucleosome antibodies with disease flare in serologically active clinically quiescent patients with systemic lupus erythematosus
    • 1:CAS:528:DC%2BD2sXkslyqtQ%3D%3D
    • Ng KP, Manson JJ, Rahman A, Isenberg DA. Association of antinucleosome antibodies with disease flare in serologically active clinically quiescent patients with systemic lupus erythematosus. Arthr Care Res. 2006;55(6):900-4.
    • (2006) Arthr Care Res , vol.55 , Issue.6 , pp. 900-904
    • Ng, K.P.1    Manson, J.J.2    Rahman, A.3    Isenberg, D.A.4
  • 10
    • 0022573072 scopus 로고
    • Predictive value of complement profiles and anti-dsDNA in systemic lupus erythematosus
    • 3487292 1:STN:280:DyaL283ktFSjsw%3D%3D
    • Swaak AJ, Groenwold J, Bronsveld W. Predictive value of complement profiles and anti-dsDNA in systemic lupus erythematosus. Ann Rheum Dis. 1986;45(5):359-66.
    • (1986) Ann Rheum Dis , vol.45 , Issue.5 , pp. 359-366
    • Swaak, A.J.1    Groenwold, J.2    Bronsveld, W.3
  • 11
    • 0032493059 scopus 로고    scopus 로고
    • Antibodies to DNA
    • 9571257 1:CAS:528:DyaK1cXjtF2nu7w%3D
    • Hahn BH. Antibodies to DNA. New Engl J Med. 1998;338(19):1359-68.
    • (1998) New Engl J Med , vol.338 , Issue.19 , pp. 1359-1368
    • Hahn, B.H.1
  • 12
    • 0020403592 scopus 로고
    • Independent expression of autoantibodies in systemic lupus erythematosus
    • 6983576 1:STN:280:DyaL3s%2FosFGksg%3D%3D
    • McCarty GA, Rice JR, Bembe ML, Pisetsky DS. Independent expression of autoantibodies in systemic lupus erythematosus. J Rheumatol. 1982;9:691-5.
    • (1982) J Rheumatol , vol.9 , pp. 691-695
    • McCarty, G.A.1    Rice, J.R.2    Bembe, M.L.3    Pisetsky, D.S.4
  • 13
    • 72949113702 scopus 로고    scopus 로고
    • How did our complex immune system evolve?
    • Cooper MD, Herrin BR. How did our complex immune system evolve? Nat Rev Immunol. 2011;10(1):2-3.
    • (2011) Nat Rev Immunol , vol.10 , Issue.1 , pp. 2-3
    • Cooper, M.D.1    Herrin, B.R.2
  • 14
    • 79957633257 scopus 로고    scopus 로고
    • Autoantibodies to intracellular antigens: Generation and pathogenetic role
    • 21397735 1:CAS:528:DC%2BC3MXntFGntbk%3D
    • Racanelli V, Prete M, Musaraj G, Dammacco F, Perosa F. Autoantibodies to intracellular antigens: generation and pathogenetic role. Autoimmun Rev. 2011;10(8):503-8.
    • (2011) Autoimmun Rev , vol.10 , Issue.8 , pp. 503-508
    • Racanelli, V.1    Prete, M.2    Musaraj, G.3    Dammacco, F.4    Perosa, F.5
  • 15
    • 0029086996 scopus 로고
    • Human IgG anti-DNA antibodies deposit in kidneys and induce proteinuria in SCID mice
    • 7474655 1:CAS:528:DyaK2MXosF2ntr0%3D
    • Ehrenstein MR, Katz DR, Griffiths MH, Papadaki L, Winkler TH, Kalden JR, et al. Human IgG anti-DNA antibodies deposit in kidneys and induce proteinuria in SCID mice. Kidney Int. 1995;48(3):705-11.
    • (1995) Kidney Int , vol.48 , Issue.3 , pp. 705-711
    • Ehrenstein, M.R.1    Katz, D.R.2    Griffiths, M.H.3    Papadaki, L.4    Winkler, T.H.5    Kalden, J.R.6
  • 16
    • 16744362427 scopus 로고    scopus 로고
    • Clinical significance of anti-dsDNA antibody isotypes: IgG/IgM ratio of anti-dsDNA antibodies as a prognostic marker for lupus nephritis
    • 14870916 1:STN:280:DC%2BD2c%2FmvFamtg%3D%3D
    • Forger F, Matthias T, Oppermann M, Becker H, Helmke K. Clinical significance of anti-dsDNA antibody isotypes: IgG/IgM ratio of anti-dsDNA antibodies as a prognostic marker for lupus nephritis. Lupus. 2004;13(1):36-44.
    • (2004) Lupus , vol.13 , Issue.1 , pp. 36-44
    • Forger, F.1    Matthias, T.2    Oppermann, M.3    Becker, H.4    Helmke, K.5
  • 17
    • 34247368484 scopus 로고    scopus 로고
    • Molecular and cellular basis for pathogenicity of autoantibodies: Lessons from murine monoclonal autoantibodies
    • 1:CAS:528:DC%2BD28Xht1CqurrF
    • Baudino L, Azeredo da Silveira S, Nakata M, Izui S. Molecular and cellular basis for pathogenicity of autoantibodies: lessons from murine monoclonal autoantibodies. Springer Semin Immun. 2006;28(2):175-84.
    • (2006) Springer Semin Immun , vol.28 , Issue.2 , pp. 175-184
    • Baudino, L.1    Azeredo Da Silveira, S.2    Nakata, M.3    Izui, S.4
  • 18
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • 12920303 1:CAS:528:DC%2BD3sXmvFeltbo%3D
    • Wardemann H, Yurasov S, Schaefer A, Young JW, Meffre E, Nussenzweig MC. Predominant autoantibody production by early human B cell precursors. Science. 2003;301(5638):1374-7.
    • (2003) Science , vol.301 , Issue.5638 , pp. 1374-1377
    • Wardemann, H.1    Yurasov, S.2    Schaefer, A.3    Young, J.W.4    Meffre, E.5    Nussenzweig, M.C.6
  • 19
    • 51149085208 scopus 로고    scopus 로고
    • Nature and functions of autoantibodies
    • 1:CAS:528:DC%2BD1cXhtVGgsb7F
    • Elkon K, Casali P. Nature and functions of autoantibodies. Nat Clin Pract Rheum. 2008;4(9):491-8.
    • (2008) Nat Clin Pract Rheum , vol.4 , Issue.9 , pp. 491-498
    • Elkon, K.1    Casali, P.2
  • 20
    • 35448975223 scopus 로고    scopus 로고
    • Properties and function of polyreactive antibodies and polyreactive antigen-binding B cells
    • 17888628 1:CAS:528:DC%2BD2sXht1amsrfN
    • Zhou Z-H, Tzioufas AG, Notkins AL. Properties and function of polyreactive antibodies and polyreactive antigen-binding B cells. J Autoimmun. 2007;29(4):219-28.
    • (2007) J Autoimmun , vol.29 , Issue.4 , pp. 219-228
    • Zhou, Z.-H.1    Tzioufas, A.G.2    Notkins, A.L.3
  • 21
    • 33947721996 scopus 로고    scopus 로고
    • The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies
    • 18005681 1:CAS:528:DC%2BD2sXkvFSms7Y%3D
    • Zhou Z-H, Zhang Y, Hu Y-F, Wahl LM, Cisar JO, Notkins AL. The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies. Cell Host Microbe. 2007;1(1):51-61.
    • (2007) Cell Host Microbe , vol.1 , Issue.1 , pp. 51-61
    • Zhou, Z.-H.1    Zhang, Y.2    Hu, Y.-F.3    Wahl, L.M.4    Cisar, J.O.5    Notkins, A.L.6
  • 22
    • 34548364099 scopus 로고    scopus 로고
    • Regulation of autoreactive antibodies
    • 17762605 1:CAS:528:DC%2BD2sXpvVensbs%3D
    • Yurasov S, Nussenzweig MC. Regulation of autoreactive antibodies. Curr Opin Rheumatol. 2007;19:421-6.
    • (2007) Curr Opin Rheumatol , vol.19 , pp. 421-426
    • Yurasov, S.1    Nussenzweig, M.C.2
  • 23
    • 58149463903 scopus 로고    scopus 로고
    • Naturally occurring auto-antibodies in homeostasis and disease
    • 19058756 1:CAS:528:DC%2BD1MXktF2kug%3D%3D
    • Lutz HU, Binder CJ, Kaveri S. Naturally occurring auto-antibodies in homeostasis and disease. Trends Immunol. 2009;30(1):43-51.
    • (2009) Trends Immunol , vol.30 , Issue.1 , pp. 43-51
    • Lutz, H.U.1    Binder, C.J.2    Kaveri, S.3
  • 24
    • 0025866286 scopus 로고
    • IgG human monoclonal anti-DNA autoantibodies from patients with systemic lupus erythematosus
    • 1893617 1:STN:280:DyaK3MzntFKkug%3D%3D
    • Winkler TH, Jahn S, Kalden JR. IgG human monoclonal anti-DNA autoantibodies from patients with systemic lupus erythematosus. Clin Exp Immunol. 1991;85(3):379-85.
    • (1991) Clin Exp Immunol , vol.85 , Issue.3 , pp. 379-385
    • Winkler, T.H.1    Jahn, S.2    Kalden, J.R.3
  • 25
    • 0026740330 scopus 로고
    • Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas
    • 1623920 1:CAS:528:DyaK38XlsV2isL4%3D
    • Winkler TH, Fehr H, Kalden JR. Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas. Eur J Immunol. 1992;22(7):1719-28.
    • (1992) Eur J Immunol , vol.22 , Issue.7 , pp. 1719-1728
    • Winkler, T.H.1    Fehr, H.2    Kalden, J.R.3
  • 26
    • 0026761402 scopus 로고
    • Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB × NZW)F1 mice
    • 1512540 1:CAS:528:DyaK3sXmt1Cjs7k%3D
    • Tillman DM, Jou NT, Hill RJ, Marion TN. Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB × NZW)F1 mice. J Exp Med. 1992;176(3):761-79.
    • (1992) J Exp Med , vol.176 , Issue.3 , pp. 761-779
    • Tillman, D.M.1    Jou, N.T.2    Hill, R.J.3    Marion, T.N.4
  • 27
    • 0023462643 scopus 로고
    • Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse
    • 3480535 1:CAS:528:DyaL1cXpt12jsw%3D%3D
    • Shlomchik MJ, Aucoin AH, Pisetsky DS, Weigert MG. Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse. Proc Natl Acad Sci USA. 1987;84(24):9150-4.
    • (1987) Proc Natl Acad Sci USA , vol.84 , Issue.24 , pp. 9150-9154
    • Shlomchik, M.J.1    Aucoin, A.H.2    Pisetsky, D.S.3    Weigert, M.G.4
  • 28
    • 0030587073 scopus 로고    scopus 로고
    • Correlation between the amino acid position of arginine in VH-CDR3 and specificity for native DNA among autoimmune antibodies
    • 8805642 1:CAS:528:DyaK28Xls1aisrY%3D
    • Krishnan MR, Jou NT, Marion TN. Correlation between the amino acid position of arginine in VH-CDR3 and specificity for native DNA among autoimmune antibodies. J Immunol. 1996;157(6):2430-9.
    • (1996) J Immunol , vol.157 , Issue.6 , pp. 2430-2439
    • Krishnan, M.R.1    Jou, N.T.2    Marion, T.N.3
  • 29
    • 0027215784 scopus 로고
    • Residues that mediate DNA binding of autoimmune antibodies
    • 8496598 1:CAS:528:DyaK3sXkvFehu7k%3D
    • Radic MZ, Mackle J, Erikson J, Mol C, Anderson WF, Weigert M. Residues that mediate DNA binding of autoimmune antibodies. J Immunol. 1993;150(11):4966-77.
    • (1993) J Immunol , vol.150 , Issue.11 , pp. 4966-4977
    • Radic, M.Z.1    Mackle, J.2    Erikson, J.3    Mol, C.4    Anderson, W.F.5    Weigert, M.6
  • 30
    • 0033924552 scopus 로고    scopus 로고
    • Structure-function analysis of a lupus anti-DNA autoantibody: Central role of the heavy chain complementarity-determining region 3 Arg in binding of double- and single-stranded DNA
    • 10940891 1:CAS:528:DC%2BD3cXlt1Gisbs%3D
    • Li Z, Schettino EW, Padlan EA, Ikematsu H, Casali P. Structure-function analysis of a lupus anti-DNA autoantibody: central role of the heavy chain complementarity-determining region 3 Arg in binding of double- and single-stranded DNA. Eur J Immunol. 2000;30(7):2015-26.
    • (2000) Eur J Immunol , vol.30 , Issue.7 , pp. 2015-2026
    • Li, Z.1    Schettino, E.W.2    Padlan, E.A.3    Ikematsu, H.4    Casali, P.5
  • 31
    • 0025017688 scopus 로고
    • Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation
    • 2104919 1:CAS:528:DyaK3cXhtFegsL8%3D
    • Shlomchik M, Mascelli M, Shan H, Radic MZ, Pisetsky D, Marshak-Rothstein A, et al. Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J Exp Med. 1990;171(1):265-92.
    • (1990) J Exp Med , vol.171 , Issue.1 , pp. 265-292
    • Shlomchik, M.1    Mascelli, M.2    Shan, H.3    Radic, M.Z.4    Pisetsky, D.5    Marshak-Rothstein, A.6
  • 32
    • 0027182519 scopus 로고
    • Antigen-specific induction of antibodies against native mammalian DNA in nonautoimmune mice
    • 8393048 1:CAS:528:DyaK3sXmsVOmtbk%3D
    • Desai DD, Krishnan MR, Swindle JT, Marion TN. Antigen-specific induction of antibodies against native mammalian DNA in nonautoimmune mice. J Immunol. 1993;151(3):1614-26.
    • (1993) J Immunol , vol.151 , Issue.3 , pp. 1614-1626
    • Desai, D.D.1    Krishnan, M.R.2    Swindle, J.T.3    Marion, T.N.4
  • 33
    • 0033739280 scopus 로고    scopus 로고
    • Induction of anti-DNA antibody with DNA-peptide complexes
    • 11058577 1:CAS:528:DC%2BD3cXosVWjurw%3D
    • Desai DD, Marion TN. Induction of anti-DNA antibody with DNA-peptide complexes. Int Immunol. 2000;12(11):1569-78.
    • (2000) Int Immunol , vol.12 , Issue.11 , pp. 1569-1578
    • Desai, D.D.1    Marion, T.N.2
  • 34
    • 0028288510 scopus 로고
    • Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
    • 7511686 1:CAS:528:DyaK2cXhs1Wms7Y%3D
    • Casciola-Rosen LA, Anhalt G, Rosen A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med. 1994;179(4):1317-30.
    • (1994) J Exp Med , vol.179 , Issue.4 , pp. 1317-1330
    • Casciola-Rosen, L.A.1    Anhalt, G.2    Rosen, A.3
  • 35
    • 77956931638 scopus 로고    scopus 로고
    • Inefficient clearance of dying cells in patients with SLE: Anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players
    • 20198437 1:CAS:528:DC%2BC3cXhtVyrurfK
    • Kruse K, Janko C, Urbonaviciute V, Mierke C, Winkler T, Voll R, et al. Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players. Apoptosis. 2010;15(9):1098-113.
    • (2010) Apoptosis , vol.15 , Issue.9 , pp. 1098-1113
    • Kruse, K.1    Janko, C.2    Urbonaviciute, V.3    Mierke, C.4    Winkler, T.5    Voll, R.6
  • 37
    • 0031825552 scopus 로고    scopus 로고
    • Systemic exposure to irradiated apoptotic cells induces autoantibody production
    • 9670050 1:CAS:528:DyaK1cXkvVaqtLs%3D
    • Mevorach D, Zhou JL, Song X, Elkon KB. Systemic exposure to irradiated apoptotic cells induces autoantibody production. J Exp Med. 1998;188(2):387-92.
    • (1998) J Exp Med , vol.188 , Issue.2 , pp. 387-392
    • Mevorach, D.1    Zhou, J.L.2    Song, X.3    Elkon, K.B.4
  • 38
    • 0036178402 scopus 로고    scopus 로고
    • Secretion of a peripheral membrane protein, MFG-E8, as a complex with membrane vesicles
    • 11856354 1:CAS:528:DC%2BD38XhslOru7s%3D
    • Oshima K, Aoki N, Kato T, Kitajima K, Matsuda T. Secretion of a peripheral membrane protein, MFG-E8, as a complex with membrane vesicles. Eur J Biochem. 2002;269(4):1209-18.
    • (2002) Eur J Biochem , vol.269 , Issue.4 , pp. 1209-1218
    • Oshima, K.1    Aoki, N.2    Kato, T.3    Kitajima, K.4    Matsuda, T.5
  • 39
    • 0037046580 scopus 로고    scopus 로고
    • Identification of a factor that links apoptotic cells to phagocytes
    • 12000961 1:CAS:528:DC%2BD38Xjs1SqsLc%3D
    • Hanayama R, Tanaka M, Miwa K, Shinohara A, Iwamatsu A, Nagata S. Identification of a factor that links apoptotic cells to phagocytes. Nature. 2002;417(6885):182-7.
    • (2002) Nature , vol.417 , Issue.6885 , pp. 182-187
    • Hanayama, R.1    Tanaka, M.2    Miwa, K.3    Shinohara, A.4    Iwamatsu, A.5    Nagata, S.6
  • 40
    • 2442665179 scopus 로고    scopus 로고
    • Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice
    • 15155946 1:CAS:528:DC%2BD2cXktVyit7o%3D
    • Hanayama R, Tanaka M, Miyasaka K, Aozasa K, Koike M, Uchiyama Y, et al. Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science. 2004;304(5674):1147-50.
    • (2004) Science , vol.304 , Issue.5674 , pp. 1147-1150
    • Hanayama, R.1    Tanaka, M.2    Miyasaka, K.3    Aozasa, K.4    Koike, M.5    Uchiyama, Y.6
  • 41
    • 4944233473 scopus 로고    scopus 로고
    • Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis
    • 15213101 1:CAS:528:DC%2BD2cXovVegtbk%3D
    • Gasser O, Schifferli Jr A. Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis. Blood. 2004;104(8):2543-8.
    • (2004) Blood , vol.104 , Issue.8 , pp. 2543-2548
    • Gasser, O.1    Schifferli Jr., A.2
  • 43
    • 0033929004 scopus 로고    scopus 로고
    • Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: A mechanism for cellular human immunodeficiency virus 1 infection
    • 10888925 1:CAS:528:DC%2BD3cXltValsLo%3D
    • Mack M, Kleinschmidt A, Bruhl H, Klier C, Nelson PJ, Cihak J, et al. Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection. Nat Med. 2000;6(7):769-75.
    • (2000) Nat Med , vol.6 , Issue.7 , pp. 769-775
    • Mack, M.1    Kleinschmidt, A.2    Bruhl, H.3    Klier, C.4    Nelson, P.J.5    Cihak, J.6
  • 44
    • 75149125508 scopus 로고    scopus 로고
    • The role of microparticles in the pathogenesis of rheumatic diseases
    • 19949432 1:CAS:528:DC%2BC3cXotlSn
    • Beyer C, Pisetsky DS. The role of microparticles in the pathogenesis of rheumatic diseases. Nat Rev Rheumatol. 2010;6(1):21-9.
    • (2010) Nat Rev Rheumatol , vol.6 , Issue.1 , pp. 21-29
    • Beyer, C.1    Pisetsky, D.S.2
  • 45
    • 78649853114 scopus 로고    scopus 로고
    • Activation of macrophages by P2X7-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4
    • 20709956 1:CAS:528:DC%2BC3cXhtFSntLnM
    • Thomas LM, Salter RD. Activation of macrophages by P2X7-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4. J Immunol. 2010;185(6):3740-9.
    • (2010) J Immunol , vol.185 , Issue.6 , pp. 3740-3749
    • Thomas, L.M.1    Salter, R.D.2
  • 47
    • 33846432787 scopus 로고    scopus 로고
    • Novel cell death program leads to neutrophil extracellular traps
    • 17210947 1:CAS:528:DC%2BD2sXpt1egtQ%3D%3D
    • Fuchs TA, Abed U, Goosmann C, Hurwitz R, Schulze I, Wahn V, et al. Novel cell death program leads to neutrophil extracellular traps. J Cell Biol. 2007;176(2):231-41.
    • (2007) J Cell Biol , vol.176 , Issue.2 , pp. 231-241
    • Fuchs, T.A.1    Abed, U.2    Goosmann, C.3    Hurwitz, R.4    Schulze, I.5    Wahn, V.6
  • 48
    • 34147188469 scopus 로고    scopus 로고
    • Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
    • 17384648 1:CAS:528:DC%2BD2sXjvVaqur0%3D
    • Clark SR, Ma AC, Tavener SA, McDonald B, Goodarzi Z, Kelly MM, et al. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med. 2007;13(4):463-9.
    • (2007) Nat Med , vol.13 , Issue.4 , pp. 463-469
    • Clark, S.R.1    Ma, A.C.2    Tavener, S.A.3    McDonald, B.4    Goodarzi, Z.5    Kelly, M.M.6
  • 49
    • 84855962862 scopus 로고    scopus 로고
    • B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen
    • 22197976
    • Puga I, Cols M, Barra CM, He B, Cassis L, Gentile M, et al. B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nat Immunol. 2011;13(2):170-80.
    • (2011) Nat Immunol , vol.13 , Issue.2 , pp. 170-180
    • Puga, I.1    Cols, M.2    Barra, C.M.3    He, B.4    Cassis, L.5    Gentile, M.6
  • 50
    • 77953088427 scopus 로고    scopus 로고
    • Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis
    • 20439745 1:CAS:528:DC%2BC3cXntFGqt74%3D
    • Hakkim A, Funrohr BG, Amann K, Laube B, Abed UA, Brinkmann V, et al. Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis. Proc Natl Acad Sci USA. 2010;107(21):9813-8.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.21 , pp. 9813-9818
    • Hakkim, A.1    Funrohr, B.G.2    Amann, K.3    Laube, B.4    Abed, U.A.5    Brinkmann, V.6
  • 51
    • 66849089035 scopus 로고    scopus 로고
    • Incidence and risk factors of infection in a single cohort of 110 adults with systemic lupus erythematosus
    • 19172435
    • Jeong SJ, Choi H, Lee HS, Han SH, Chin BS, Baek J-H, et al. Incidence and risk factors of infection in a single cohort of 110 adults with systemic lupus erythematosus. Scand J Infect Dis. 2009;41(4):268-74.
    • (2009) Scand J Infect Dis , vol.41 , Issue.4 , pp. 268-274
    • Jeong, S.J.1    Choi, H.2    Lee, H.S.3    Han, S.H.4    Chin, B.S.5    Baek, J.-H.6
  • 52
    • 0035036288 scopus 로고    scopus 로고
    • Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure
    • 1:STN:280:DC%2BD3M3lsVWlsQ%3D%3D
    • James JA, Neas BR, Moser KL, Hall T, Bruner GR, Sestak AL, et al. Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure. Arthr Rheum. 2001;44(5):1122-6.
    • (2001) Arthr Rheum , vol.44 , Issue.5 , pp. 1122-1126
    • James, J.A.1    Neas, B.R.2    Moser, K.L.3    Hall, T.4    Bruner, G.R.5    Sestak, A.L.6
  • 53
    • 0031465706 scopus 로고    scopus 로고
    • An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus
    • 9399948 1:CAS:528:DyaK2sXotVyrsr8%3D
    • James JA, Kaufman KM, Farris AD, Taylor-Albert E, Lehman TJ, Harley JB. An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest. 1997;100(12):3019-26.
    • (1997) J Clin Invest , vol.100 , Issue.12 , pp. 3019-3026
    • James, J.A.1    Kaufman, K.M.2    Farris, A.D.3    Taylor-Albert, E.4    Lehman, T.J.5    Harley, J.B.6
  • 54
    • 84873318833 scopus 로고    scopus 로고
    • The role of the Epstein-Barr virus in the pathogenesis of some autoimmune disorders - Similarities and differences
    • Füst G. The role of the Epstein-Barr virus in the pathogenesis of some autoimmune disorders - similarities and differences. Eur J Microbiol Immunol. 2011;1(4):267-78.
    • (2011) Eur J Microbiol Immunol , vol.1 , Issue.4 , pp. 267-278
    • Füst, G.1
  • 55
    • 77958146282 scopus 로고    scopus 로고
    • Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice
    • 20810985 1:CAS:528:DC%2BC3cXhtFyisrjL
    • Peters AL, Stunz LL, Meyerholz DK, Mohan C, Bishop GA. Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice. J Immunol. 2010;185(7):4053-62.
    • (2010) J Immunol , vol.185 , Issue.7 , pp. 4053-4062
    • Peters, A.L.1    Stunz, L.L.2    Meyerholz, D.K.3    Mohan, C.4    Bishop, G.A.5
  • 56
    • 0035126502 scopus 로고    scopus 로고
    • Epstein-barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR
    • 11163230 1:CAS:528:DC%2BD3MXivVKntLo%3D
    • Dykstra ML, Longnecker R, Pierce SK. Epstein-barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR. Immunity. 2001;14(1):57-67.
    • (2001) Immunity , vol.14 , Issue.1 , pp. 57-67
    • Dykstra, M.L.1    Longnecker, R.2    Pierce, S.K.3
  • 57
    • 33745781482 scopus 로고    scopus 로고
    • Epstein-barr virus LMP2A enhances B-cell responses in vivo and in vitro
    • 16809282 1:CAS:528:DC%2BD28XmvVais7k%3D
    • Swanson-Mungerson M, Bultema R, Longnecker R. Epstein-barr virus LMP2A enhances B-cell responses in vivo and in vitro. J Virol. 2006;80(14):6764-70.
    • (2006) J Virol , vol.80 , Issue.14 , pp. 6764-6770
    • Swanson-Mungerson, M.1    Bultema, R.2    Longnecker, R.3
  • 58
    • 79251567049 scopus 로고    scopus 로고
    • Antibodies elicited in response to EBNA-1 may cross-react with dsDNA
    • 21245919 1:CAS:528:DC%2BC3MXosVKrug%3D%3D
    • Yadav P, Tran H, Ebegbe R, Gottlieb P, Wei H, Lewis RH, et al. Antibodies elicited in response to EBNA-1 may cross-react with dsDNA. PLoS ONE. 2011;6(1):e14488.
    • (2011) PLoS ONE , vol.6 , Issue.1 , pp. 14488
    • Yadav, P.1    Tran, H.2    Ebegbe, R.3    Gottlieb, P.4    Wei, H.5    Lewis, R.H.6
  • 59
    • 0023003312 scopus 로고
    • Monoclonal anti-tuberculosis antibodies react with DNA and monoclonal anti-DNA autoantibodies react with Mycobacterium tuberculosis
    • Shoenfeld Y, Vilner Y, Coates ARM, Rauch J, Lavie G, Shaul D, et al. Monoclonal anti-tuberculosis antibodies react with DNA and monoclonal anti-DNA autoantibodies react with Mycobacterium tuberculosis. Clin Exp Immunol. 1986;66:1-265.
    • (1986) Clin Exp Immunol , vol.66 , pp. 1-265
    • Shoenfeld, Y.1    Vilner, Y.2    Coates, A.R.M.3    Rauch, J.4    Lavie, G.5    Shaul, D.6
  • 60
    • 0034953516 scopus 로고    scopus 로고
    • Crossreactivity of human anti-dsDNA antibodies to phosphorylcholine: Clues to their origin
    • 11437497 1:STN:280:DC%2BD38%2FhvFKrtQ%3D%3D
    • Sharma A, Isenberg DA, Diamond B. Crossreactivity of human anti-dsDNA antibodies to phosphorylcholine: clues to their origin. J Autoimmun. 2001;16(4):479-84.
    • (2001) J Autoimmun , vol.16 , Issue.4 , pp. 479-484
    • Sharma, A.1    Isenberg, D.A.2    Diamond, B.3
  • 61
    • 49749101685 scopus 로고    scopus 로고
    • A possible link between infection with Burkholderia bacteria and systemic lupus erythematosus based on epitope mimicry
    • doi: 10.1155/2008/683489.
    • Zhang W, Reichlin M. A possible link between infection with Burkholderia bacteria and systemic lupus erythematosus based on epitope mimicry. Clin Dev Immunol. 2008. doi: 10.1155/2008/683489.
    • (2008) Clin Dev Immunol.
    • Zhang, W.1    Reichlin, M.2
  • 62
    • 0027511760 scopus 로고
    • The role of autoantibodies in autoimmune disease
    • 8476578 1:CAS:528:DyaK3sXktVKmu78%3D
    • Naparstek Y, Plotz PH. The role of autoantibodies in autoimmune disease. Annu Rev Immunol. 1993;11:79-104.
    • (1993) Annu Rev Immunol , vol.11 , pp. 79-104
    • Naparstek, Y.1    Plotz, P.H.2
  • 63
    • 0035684793 scopus 로고    scopus 로고
    • An analysis of clinical disease activity and nephritis-associated serum autoantibody profiles in patients with systemic lupus erythematosus: A cross-sectional study
    • 11752513 1:STN:280:DC%2BD38%2FgsVGgsQ%3D%3D
    • Ravirajan CT, Rowse L, MacGowan JR, Isenberg DA. An analysis of clinical disease activity and nephritis-associated serum autoantibody profiles in patients with systemic lupus erythematosus: a cross-sectional study. Rheumatology. 2001;40(12):1405-12.
    • (2001) Rheumatology , vol.40 , Issue.12 , pp. 1405-1412
    • Ravirajan, C.T.1    Rowse, L.2    Macgowan, J.R.3    Isenberg, D.A.4
  • 64
    • 0347246521 scopus 로고    scopus 로고
    • Long-term follow-up of autoantibody profiles in black female lupus patients and clinical comparison with Caucasian and Asian patients
    • 1:STN:280:DyaK2s3nvFCqtw%3D%3D
    • Isenberg DA, Garton M, Reichlin MW, Reichlin M. Long-term follow-up of autoantibody profiles in black female lupus patients and clinical comparison with Caucasian and Asian patients. Rheumatology. 1997;36(2):229-33.
    • (1997) Rheumatology , vol.36 , Issue.2 , pp. 229-233
    • Isenberg, D.A.1    Garton, M.2    Reichlin, M.W.3    Reichlin, M.4
  • 65
    • 0027463332 scopus 로고
    • Significance of enzyme linked immunosorbent assay (ELISA) for antibodies to double stranded and single stranded DNA in patients with lupus nephritis: Correlation with severity of renal histology
    • 8427508 1:STN:280:DyaK3s7ltFKmtQ%3D%3D
    • Okamura M, Kanayama Y, Amastu K, Negoro N, Kohda S, Takeda T, et al. Significance of enzyme linked immunosorbent assay (ELISA) for antibodies to double stranded and single stranded DNA in patients with lupus nephritis: correlation with severity of renal histology. Ann Rheum Dis. 1993;52(1):14-20.
    • (1993) Ann Rheum Dis , vol.52 , Issue.1 , pp. 14-20
    • Okamura, M.1    Kanayama, Y.2    Amastu, K.3    Negoro, N.4    Kohda, S.5    Takeda, T.6
  • 66
    • 0026814959 scopus 로고
    • Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo
    • 1627759 1:CAS:528:DyaK38XksVKgu78%3D
    • Vlahakos D, Foster MH, Ucci AA, Barrett KJ, Datta SK, Madaio MP. Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo. J Am Soc Nephrol. 1992;2(8):1345-54.
    • (1992) J Am Soc Nephrol , vol.2 , Issue.8 , pp. 1345-1354
    • Vlahakos, D.1    Foster, M.H.2    Ucci, A.A.3    Barrett, K.J.4    Datta, S.K.5    Madaio, M.P.6
  • 67
    • 0030240078 scopus 로고    scopus 로고
    • Mechanisms of cellular penetration and nuclear localization of an anti- double strand DNA autoantibody
    • 8757330 1:CAS:528:DyaK28XltFynsrg%3D
    • Zack DJ, Stempniak M, Wong AL, Taylor C, Weisbart RH. Mechanisms of cellular penetration and nuclear localization of an anti- double strand DNA autoantibody. J Immunol. 1996;157(5):2082-8.
    • (1996) J Immunol , vol.157 , Issue.5 , pp. 2082-2088
    • Zack, D.J.1    Stempniak, M.2    Wong, A.L.3    Taylor, C.4    Weisbart, R.H.5
  • 69
    • 0032192564 scopus 로고    scopus 로고
    • Cellular penetration and nuclear localization of anti-DNA antibodies: Mechanisms, consequences, implications and applications
    • 9802940 1:STN:280:DyaK1M%2FitFGqsQ%3D%3D
    • Madaio MP, Yanase K. Cellular penetration and nuclear localization of anti-DNA antibodies: mechanisms, consequences, implications and applications. J Autoimmun. 1998;11(5):535-8.
    • (1998) J Autoimmun , vol.11 , Issue.5 , pp. 535-538
    • Madaio, M.P.1    Yanase, K.2
  • 70
    • 0030858769 scopus 로고    scopus 로고
    • Receptor-mediated cellular entry of nuclear localizing anti-DNA antibodies via myosin 1
    • 9202053 1:CAS:528:DyaK2sXksVCksbk%3D
    • Yanase K, Smith RM, Puccetti A, Jarett L, Madaio MP. Receptor-mediated cellular entry of nuclear localizing anti-DNA antibodies via myosin 1. J Clin Invest. 1997;100(1):25-31.
    • (1997) J Clin Invest , vol.100 , Issue.1 , pp. 25-31
    • Yanase, K.1    Smith, R.M.2    Puccetti, A.3    Jarett, L.4    Madaio, M.P.5
  • 71
    • 58149345670 scopus 로고    scopus 로고
    • Arginines in the CDR of anti-dsDNA autoantibodies facilitate cell internalization via electrostatic interactions
    • 18991292 1:CAS:528:DC%2BD1cXhsVymsLnL
    • Song Y-C, Sun G-H, Lee T-P, Huang JC, Yu C-L, Chen C-H, et al. Arginines in the CDR of anti-dsDNA autoantibodies facilitate cell internalization via electrostatic interactions. Eur J Immunol. 2008;38(11):3178-90.
    • (2008) Eur J Immunol , vol.38 , Issue.11 , pp. 3178-3190
    • Song, Y.-C.1    Sun, G.-H.2    Lee, T.-P.3    Huang, J.C.4    Yu, C.-L.5    Chen, C.-H.6
  • 72
    • 34447320202 scopus 로고    scopus 로고
    • Fifty years of anti-ds DNA antibodies: Are we approaching journey's end?
    • 17500073 1:CAS:528:DC%2BD2sXosVSjt7k%3D
    • Isenberg DA, Manson JJ, Ehrenstein MR, Rahman A. Fifty years of anti-ds DNA antibodies: are we approaching journey's end? Rheumatology. 2007;46(7):1052-6.
    • (2007) Rheumatology , vol.46 , Issue.7 , pp. 1052-1056
    • Isenberg, D.A.1    Manson, J.J.2    Ehrenstein, M.R.3    Rahman, A.4
  • 73
    • 33746990232 scopus 로고    scopus 로고
    • Association of α-actinin-binding anti-double-stranded DNA antibodies with lupus nephritis
    • 1:CAS:528:DC%2BD28XpsFGns70%3D
    • Renaudineau Y, Croquefer S, Jousse S, Renaudineau E, Devauchelle V, Guéguen P, et al. Association of α-actinin-binding anti-double-stranded DNA antibodies with lupus nephritis. Arthr Rheum. 2006;54(8):2523-32.
    • (2006) Arthr Rheum , vol.54 , Issue.8 , pp. 2523-2532
    • Renaudineau, Y.1    Croquefer, S.2    Jousse, S.3    Renaudineau, E.4    Devauchelle, V.5    Guéguen, P.6
  • 74
    • 1542283744 scopus 로고    scopus 로고
    • Is α-actinin a target for pathogenic anti-DNA antibodies in lupus nephritis?
    • 1:CAS:528:DC%2BD2cXjtVCrs7Y%3D
    • Mason LJ, Ravirajan CT, Rahman A, Putterman C, Isenberg DA. Is α-actinin a target for pathogenic anti-DNA antibodies in lupus nephritis? Arthr Rheum. 2004;50(3):866-70.
    • (2004) Arthr Rheum , vol.50 , Issue.3 , pp. 866-870
    • Mason, L.J.1    Ravirajan, C.T.2    Rahman, A.3    Putterman, C.4    Isenberg, D.A.5
  • 75
    • 13444270344 scopus 로고    scopus 로고
    • Cross-reactivity of human lupus anti-DNA antibodies with α-actinin and nephritogenic potential
    • 1:CAS:528:DC%2BD2MXit1GjtLs%3D
    • Zhao Z, Weinstein E, Tuzova M, Davidson A, Mundel P, Marambio P, et al. Cross-reactivity of human lupus anti-DNA antibodies with α-actinin and nephritogenic potential. Arthr Rheum. 2005;52(2):522-30.
    • (2005) Arthr Rheum , vol.52 , Issue.2 , pp. 522-530
    • Zhao, Z.1    Weinstein, E.2    Tuzova, M.3    Davidson, A.4    Mundel, P.5    Marambio, P.6
  • 76
    • 0031883046 scopus 로고    scopus 로고
    • Expression of N-Methyl-D-Aspartate receptor subunit mRNAs in the human brain: Hippocampus and cortex
    • 9456177 1:CAS:528:DyaK1cXhvVygtA%3D%3D
    • Scherzer CR, Landwehrmeyer GB, Kerner JA, Counihan TJ, Kosinski CM, Standaert DG, et al. Expression of N-Methyl-D-Aspartate receptor subunit mRNAs in the human brain: Hippocampus and cortex. J Comp Neurol. 1998;390(1):75-90.
    • (1998) J Comp Neurol , vol.390 , Issue.1 , pp. 75-90
    • Scherzer, C.R.1    Landwehrmeyer, G.B.2    Kerner, J.A.3    Counihan, T.J.4    Kosinski, C.M.5    Standaert, D.G.6
  • 77
    • 0032946772 scopus 로고    scopus 로고
    • The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes
    • The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes. Arthr Rheum. 1999;42(4):599-8.
    • (1999) Arthr Rheum. , vol.42 , Issue.4 , pp. 599-599
  • 78
    • 0034076609 scopus 로고    scopus 로고
    • Emotion circuits in the brain
    • 10845062 1:CAS:528:DC%2BD3cXjs1Gmsr4%3D
    • LeDoux JE. Emotion circuits in the brain. Annu Rev Neurosci. 2000;23(1):155-84.
    • (2000) Annu Rev Neurosci , vol.23 , Issue.1 , pp. 155-184
    • Ledoux, J.E.1
  • 79
    • 33845893222 scopus 로고    scopus 로고
    • Human lupus autoantibodies against NMDA receptors mediate cognitive impairment
    • 17170137 1:CAS:528:DC%2BD2sXivVKltw%3D%3D
    • Kowal C, DeGiorgio LA, Lee JY, Edgar MA, Huerta PT, Volpe BT, et al. Human lupus autoantibodies against NMDA receptors mediate cognitive impairment. Proc Natl Acad Sci USA. 2006;103(52):19854-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.52 , pp. 19854-19859
    • Kowal, C.1    Degiorgio, L.A.2    Lee, J.Y.3    Edgar, M.A.4    Huerta, P.T.5    Volpe, B.T.6
  • 81
    • 0035173156 scopus 로고    scopus 로고
    • A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus
    • 11689882 1:CAS:528:DC%2BD3MXotlKltLw%3D
    • DeGiorgio LA. A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus. Nat Med. 2001;7:1189-93.
    • (2001) Nat Med , vol.7 , pp. 1189-1193
    • Degiorgio, L.A.1
  • 82
    • 0016744449 scopus 로고
    • The prognostic and therapeutic implications of DNA:anti-DNA immune complexes in systemic lupus erythematosus (SLE)
    • 1166858
    • Bardana EJ, Harbeck RJ, Hoffman AA, Pirofsky B, Carr RI. The prognostic and therapeutic implications of DNA:anti-DNA immune complexes in systemic lupus erythematosus (SLE). Am J Med. 1975;59(4):515-22.
    • (1975) Am J Med , vol.59 , Issue.4 , pp. 515-522
    • Bardana, E.J.1    Harbeck, R.J.2    Hoffman, A.A.3    Pirofsky, B.4    Carr, R.I.5
  • 83
    • 0017367766 scopus 로고
    • Serum immune complexes and disease activity in lupus nephritis
    • Levinsky RJ, Cameron JS, Soothill JF. Serum immune complexes and disease activity in lupus nephritis. Lancet. 1977;309(8011):564-7.
    • (1977) Lancet , vol.309 , Issue.8011 , pp. 564-567
    • Levinsky, R.J.1    Cameron, J.S.2    Soothill, J.F.3
  • 84
    • 0025284721 scopus 로고
    • Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone
    • 2365827 1:CAS:528:DyaK3cXkvFGltbg%3D
    • Rumore PM, Steinman CR. Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone. J Clin Invest. 1990;86(1):69-74.
    • (1990) J Clin Invest , vol.86 , Issue.1 , pp. 69-74
    • Rumore, P.M.1    Steinman, C.R.2
  • 85
    • 0031456855 scopus 로고    scopus 로고
    • Circulating plasma levels of nucleosomes in patients with systemic lupus erythematosus. Correlation with serum antinucleosome antibody titers and absence of clear association with disease activity
    • 1:STN:280:DyaK1c%2FnslensA%3D%3D
    • Amoura Z, Piette J-C, Chabre H, Cacoub P, Papo T, Wechsler B, et al. Circulating plasma levels of nucleosomes in patients with systemic lupus erythematosus. Correlation with serum antinucleosome antibody titers and absence of clear association with disease activity. Arthr Rheum. 1997;40(12):2217-25.
    • (1997) Arthr Rheum , vol.40 , Issue.12 , pp. 2217-2225
    • Amoura, Z.1    Piette, J.-C.2    Chabre, H.3    Cacoub, P.4    Papo, T.5    Wechsler, B.6
  • 86
    • 0028015572 scopus 로고
    • Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo
    • 8040312 1:CAS:528:DyaK2cXlsFGms7g%3D
    • Kramers C, Hylkema MN, van Bruggen MC, van de Lagemaat R, Dijkman HB, Assmann KJ, et al. Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo. J Clin Invest. 1994;94(2):568-77.
    • (1994) J Clin Invest , vol.94 , Issue.2 , pp. 568-577
    • Kramers, C.1    Hylkema, M.N.2    Van Bruggen, M.C.3    Van De Lagemaat, R.4    Dijkman, H.B.5    Assmann, K.J.6
  • 87
    • 33744756400 scopus 로고    scopus 로고
    • Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells
    • 16723695 1:CAS:528:DC%2BD28XlvVOhs7o%3D
    • Kalaaji M, Mortensen E, Jorgensen L, Olsen R, Rekvig OP. Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells. Am J Pathol. 2006;168(6):1779-92.
    • (2006) Am J Pathol , vol.168 , Issue.6 , pp. 1779-1792
    • Kalaaji, M.1    Mortensen, E.2    Jorgensen, L.3    Olsen, R.4    Rekvig, O.P.5
  • 88
    • 29244450802 scopus 로고    scopus 로고
    • Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
    • 16341217 1:CAS:528:DC%2BD2MXhtlSqu73E
    • Barton GM, Kagan JC, Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol. 2006;7(1):49-56.
    • (2006) Nat Immunol , vol.7 , Issue.1 , pp. 49-56
    • Barton, G.M.1    Kagan, J.C.2    Medzhitov, R.3
  • 89
    • 85047693371 scopus 로고    scopus 로고
    • Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9
    • 15668740 1:CAS:528:DC%2BD2MXhtFyjsbg%3D
    • Means TK, Latz E, Hayashi F, Murali MR, Golenbock DT, Luster AD. Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. J Clin Invest. 2005;115(2):407-17.
    • (2005) J Clin Invest , vol.115 , Issue.2 , pp. 407-417
    • Means, T.K.1    Latz, E.2    Hayashi, F.3    Murali, M.R.4    Golenbock, D.T.5    Luster, A.D.6
  • 90
    • 0038639795 scopus 로고    scopus 로고
    • Systemic lupus erythematosus and the type i interferon system
    • Ronnblom L, Alm G. Systemic lupus erythematosus and the type I interferon system. Arthr Res Ther. 2003;5(2):68-75.
    • (2003) Arthr Res Ther , vol.5 , Issue.2 , pp. 68-75
    • Ronnblom, L.1    Alm, G.2
  • 91
    • 79952476762 scopus 로고    scopus 로고
    • Netting neutrophils are major inducers of type i IFN production in pediatric systemic lupus erythematosus
    • Garcia-Romo GS, Caielli S, Vega B, Connolly J, Allantaz F, Xu Z et al. Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci Transl Med. 2011;3(73):73ra20.
    • (2011) Sci Transl Med. , vol.3 , Issue.73
    • Garcia-Romo, G.S.1    Caielli, S.2    Vega, B.3    Connolly, J.4    Allantaz, F.5    Xu, Z.6
  • 92
    • 79952468782 scopus 로고    scopus 로고
    • Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus
    • Lande R, Ganguly D, Facchinetti V, Frasca L, Conrad C, Gregorio J et al. Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Sci Transl Med. 2011;3(73):73ra19.
    • (2011) Sci Transl Med. , vol.3 , Issue.73
    • Lande, R.1    Ganguly, D.2    Facchinetti, V.3    Frasca, L.4    Conrad, C.5    Gregorio, J.6
  • 93
    • 0021178043 scopus 로고
    • Initiation of complement activation
    • 1:CAS:528:DyaL2cXmtVyksLk%3D
    • Lachmann PJ, Hughes-Jones NC. Initiation of complement activation. Springer Semin Immun. 1984;7(2):143-62.
    • (1984) Springer Semin Immun , vol.7 , Issue.2 , pp. 143-162
    • Lachmann, P.J.1    Hughes-Jones, N.C.2
  • 94
    • 0027953416 scopus 로고
    • Mammalian lectins in activation and clearance mechanisms involving the complement system
    • 1:CAS:528:DyaK2cXktVKlsb8%3D
    • Reid KBM, Turner MW. Mammalian lectins in activation and clearance mechanisms involving the complement system. Springer Semin Immun. 1994;15(4):307-26.
    • (1994) Springer Semin Immun , vol.15 , Issue.4 , pp. 307-326
    • Reid, K.B.M.1    Turner, M.W.2
  • 95
    • 0023890664 scopus 로고
    • Molecular organization and function of the complement system
    • 3052276 1:STN:280:DyaL1M%2FisVGktw%3D%3D
    • Muller-Eberhard HJ. Molecular organization and function of the complement system. Annu Rev Biochem. 1988;57(1):321-47.
    • (1988) Annu Rev Biochem , vol.57 , Issue.1 , pp. 321-347
    • Muller-Eberhard, H.J.1
  • 96
    • 2542505506 scopus 로고    scopus 로고
    • The role of complement in the development of systemic lupus erythematosus
    • 15032584 1:CAS:528:DC%2BD2cXktlOgsL4%3D
    • Manderson AP, Botto M, Walport MJ. The role of complement in the development of systemic lupus erythematosus. Annu Rev Immunol. 2004;22(1):431-56.
    • (2004) Annu Rev Immunol , vol.22 , Issue.1 , pp. 431-456
    • Manderson, A.P.1    Botto, M.2    Walport, M.J.3
  • 97
    • 0029926153 scopus 로고    scopus 로고
    • Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2
    • 8622941 1:CAS:528:DyaK28XisVWisbo%3D
    • Molina H, Holers VM, Li B, Fung Y, Mariathasan S, Goellner J, et al. Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2. Proc Natl Acad Sci USA. 1996;93(8):3357-61.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.8 , pp. 3357-3361
    • Molina, H.1    Holers, V.M.2    Li, B.3    Fung, Y.4    Mariathasan, S.5    Goellner, J.6
  • 98
    • 0034891226 scopus 로고    scopus 로고
    • Contribution of the innate immune system to autoimmune myocarditis: A role for complement
    • 11477411 1:CAS:528:DC%2BD3MXlslKis7Y%3D
    • Kaya Z, Afanasyeva M, Wang Y, Dohmen KM, Schlichting J, Tretter T, et al. Contribution of the innate immune system to autoimmune myocarditis: a role for complement. Nat Immunol. 2001;2(8):739-45.
    • (2001) Nat Immunol , vol.2 , Issue.8 , pp. 739-745
    • Kaya, Z.1    Afanasyeva, M.2    Wang, Y.3    Dohmen, K.M.4    Schlichting, J.5    Tretter, T.6
  • 99
    • 0037527720 scopus 로고    scopus 로고
    • The complement system as a therapeutic target in autoimmunity
    • 12804527 1:CAS:528:DC%2BD3sXksVyku7Y%3D
    • Holers VM. The complement system as a therapeutic target in autoimmunity. Clin Immunol. 2003;107(3):140-51.
    • (2003) Clin Immunol , vol.107 , Issue.3 , pp. 140-151
    • Holers, V.M.1
  • 100
    • 0034114377 scopus 로고    scopus 로고
    • Systemic lupus erythematosus with C1q deficiency
    • 1:STN:280:DC%2BD3c3gtVOntw%3D%3D
    • Stone NM, Williams A, Wilkinson JD, Bird G. Systemic lupus erythematosus with C1q deficiency. Brit J Dermatol. 2000;142(3):521-4.
    • (2000) Brit J Dermatol , vol.142 , Issue.3 , pp. 521-524
    • Stone, N.M.1    Williams, A.2    Wilkinson, J.D.3    Bird, G.4
  • 101
    • 0035877108 scopus 로고    scopus 로고
    • Molecular basis of a selective C1s deficiency associated with early onset multiple autoimmune diseases
    • 11390518 1:CAS:528:DC%2BD3MXksVOmsLY%3D
    • Dragon-Durey MA, Quartier P, Fremeaux-Bacchi V, Blouin J, de Barace C. Molecular basis of a selective C1s deficiency associated with early onset multiple autoimmune diseases. J Immunol. 2001;166(12):7612-6.
    • (2001) J Immunol , vol.166 , Issue.12 , pp. 7612-7616
    • Dragon-Durey, M.A.1    Quartier, P.2    Fremeaux-Bacchi, V.3    Blouin, J.4    De Barace, C.5
  • 102
    • 0036681601 scopus 로고    scopus 로고
    • The molecular basis of complete complement C4A and C4B deficiencies in a systemic lupus erythematosus patient with homozygous C4A and C4B mutant genes
    • 12133986 1:CAS:528:DC%2BD38XlslWhtLg%3D
    • Rupert KL, Moulds JM, Yang Y, Arnett FC, Warren RW, Reveille JD, et al. The molecular basis of complete complement C4A and C4B deficiencies in a systemic lupus erythematosus patient with homozygous C4A and C4B mutant genes. J Immunol. 2002;169(3):1570-8.
    • (2002) J Immunol , vol.169 , Issue.3 , pp. 1570-1578
    • Rupert, K.L.1    Moulds, J.M.2    Yang, Y.3    Arnett, F.C.4    Warren, R.W.5    Reveille, J.D.6
  • 103
    • 57349091732 scopus 로고    scopus 로고
    • Association of three systemic lupus erythematosus susceptibility factors, PD-1.3A, C4AQ0, and low levels of mannan-binding lectin, with autoimmune manifestations in icelandic multicase systemic lupus erythematosus families
    • 1:CAS:528:DC%2BD1MXmt1ylsQ%3D%3D
    • Kristjansdottir H, Saevarsdottir S, Gröndal G, Alarcón- Riquelme ME, Erlendsson K, Valdimarsson H, et al. Association of three systemic lupus erythematosus susceptibility factors, PD-1.3A, C4AQ0, and low levels of mannan-binding lectin, with autoimmune manifestations in icelandic multicase systemic lupus erythematosus families. Arthr Rheum. 2008;58(12):3865-72.
    • (2008) Arthr Rheum , vol.58 , Issue.12 , pp. 3865-3872
    • Kristjansdottir, H.1    Saevarsdottir, S.2    Gröndal, G.3    Alarcón- Riquelme, M.E.4    Erlendsson, K.5    Valdimarsson, H.6
  • 104
    • 0032416392 scopus 로고    scopus 로고
    • Complement-dependent clearance of apoptotic cells by human macrophages
    • 9858517 1:CAS:528:DyaK1MXhtFejsg%3D%3D
    • Mevorach D, Mascarenhas JO, Gershov D, Elkon KB. Complement-dependent clearance of apoptotic cells by human macrophages. J Exp Med. 1998;188(12):2313-20.
    • (1998) J Exp Med , vol.188 , Issue.12 , pp. 2313-2320
    • Mevorach, D.1    Mascarenhas, J.O.2    Gershov, D.3    Elkon, K.B.4
  • 105
    • 0034931306 scopus 로고    scopus 로고
    • Links between complement deficiency and apoptosis
    • 1:CAS:528:DC%2BD3MXmt1CmtbY%3D
    • Botto M. Links between complement deficiency and apoptosis. Arthr Res. 2001;3(4):207-10.
    • (2001) Arthr Res , vol.3 , Issue.4 , pp. 207-210
    • Botto, M.1
  • 106
    • 0031778836 scopus 로고    scopus 로고
    • Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
    • 9590289 1:CAS:528:DyaK1cXislWqu78%3D
    • Botto M, Dell' Agnola C, Bygrave AE, Thompson EM, Cook HT, Petry F, et al. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet. 1998;19(1):56-9.
    • (1998) Nat Genet , vol.19 , Issue.1 , pp. 56-59
    • Botto, M.1    Dell Agnola, C.2    Bygrave, A.E.3    Thompson, E.M.4    Cook, H.T.5    Petry, F.6
  • 107
    • 0022393015 scopus 로고
    • Formation of soluble immune complexes by complement in sera of patients with various hypocomplementemic states. Difference between inhibition of immune precipitation and solubilization
    • 2934406 1:STN:280:DyaL28%2Fos1emtQ%3D%3D
    • Schifferli JA, Steiger G, Hauptmann G, Spaeth PJ, Sjoholm AG. Formation of soluble immune complexes by complement in sera of patients with various hypocomplementemic states. Difference between inhibition of immune precipitation and solubilization. J Clin Invest. 1985;76(6):2127-33.
    • (1985) J Clin Invest , vol.76 , Issue.6 , pp. 2127-2133
    • Schifferli, J.A.1    Steiger, G.2    Hauptmann, G.3    Spaeth, P.J.4    Sjoholm, A.G.5
  • 108
    • 0034650431 scopus 로고    scopus 로고
    • Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B
    • 10623824 1:CAS:528:DC%2BD3cXlt1CmtA%3D%3D
    • Watanabe H, Garnier G, Circolo A, Wetsel RA, Ruiz P, Holers VM, et al. Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B. J Immunol. 2000;164(2):786-94.
    • (2000) J Immunol , vol.164 , Issue.2 , pp. 786-794
    • Watanabe, H.1    Garnier, G.2    Circolo, A.3    Wetsel, R.A.4    Ruiz, P.5    Holers, V.M.6
  • 109
    • 0347992784 scopus 로고    scopus 로고
    • Effects of complement factor D deficiency on the renal disease of MRL//lpr mice
    • 14675043 1:CAS:528:DC%2BD2cXmt1Wjtw%3D%3D
    • Elliott MK, Jarmi T, Ruiz P, Xu Y, Holers VM, Gilkeson GS. Effects of complement factor D deficiency on the renal disease of MRL//lpr mice. Kidney Int. 2004;65(1):129-38.
    • (2004) Kidney Int , vol.65 , Issue.1 , pp. 129-138
    • Elliott, M.K.1    Jarmi, T.2    Ruiz, P.3    Xu, Y.4    Holers, V.M.5    Gilkeson, G.S.6
  • 110
    • 9644280856 scopus 로고    scopus 로고
    • The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation
    • 15544620 1:CAS:528:DC%2BD2cXhtFGms7%2FN
    • Harboe M, Ulvund G, Vien L, Fung M, Mollnes TE. The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation. Clin Exp Immunol. 2004;138(3):439-46.
    • (2004) Clin Exp Immunol , vol.138 , Issue.3 , pp. 439-446
    • Harboe, M.1    Ulvund, G.2    Vien, L.3    Fung, M.4    Mollnes, T.E.5
  • 111
    • 70349437186 scopus 로고    scopus 로고
    • Complement regulators and inhibitory proteins
    • 19730437 1:CAS:528:DC%2BD1MXhtVygsLnJ
    • Zipfel PF, Skerka C. Complement regulators and inhibitory proteins. Nat Rev Immunol. 2009;9(10):729-40.
    • (2009) Nat Rev Immunol , vol.9 , Issue.10 , pp. 729-740
    • Zipfel, P.F.1    Skerka, C.2
  • 112
    • 79551664780 scopus 로고    scopus 로고
    • Complement factor H deficiency accelerates development of lupus nephritis
    • 21148254
    • Bao L, Haas M, Quigg RJ. Complement factor H deficiency accelerates development of lupus nephritis. J Am Soc Nephrol. 2011;22(2):285-95.
    • (2011) J Am Soc Nephrol , vol.22 , Issue.2 , pp. 285-295
    • Bao, L.1    Haas, M.2    Quigg, R.J.3
  • 113
    • 79957991917 scopus 로고    scopus 로고
    • Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility
    • 21637784 1:CAS:528:DC%2BC3MXntVWqu7Y%3D
    • Zhao J, Wu H, Khosravi M, Cui H, Qian X, Kelly JA, et al. Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. PLoS Genet. 2011;7(5):e1002079.
    • (2011) PLoS Genet , vol.7 , Issue.5 , pp. 1002079
    • Zhao, J.1    Wu, H.2    Khosravi, M.3    Cui, H.4    Qian, X.5    Kelly, J.A.6
  • 114
    • 70349441306 scopus 로고    scopus 로고
    • Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation
    • 10.1182/blood-2009-02-205641 19528535 1:CAS:528:DC%2BD1MXht1WktrzL
    • Heinen S, Hartmann A, Lauer N, Wiehl U, Dahse H-M, Schirmer S, et al. Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation. Blood. 2009;114(12):2439-47. doi: 10.1182/blood-2009-02-205641.
    • (2009) Blood , vol.114 , Issue.12 , pp. 2439-2447
    • Heinen, S.1    Hartmann, A.2    Lauer, N.3    Wiehl, U.4    Dahse, H.-M.5    Schirmer, S.6
  • 115
    • 78149270873 scopus 로고    scopus 로고
    • An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)
    • 10.1093/hmg/ddq399 20843825 1:CAS:528:DC%2BC3cXhtlyktrzI
    • Fritsche LG, Lauer N, Hartmann A, Stippa S, Keilhauer CN, Oppermann M, et al. An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD). Hum Mol Genet. 2010;19(23):4694-704. doi: 10.1093/hmg/ddq399.
    • (2010) Hum Mol Genet , vol.19 , Issue.23 , pp. 4694-4704
    • Fritsche, L.G.1    Lauer, N.2    Hartmann, A.3    Stippa, S.4    Keilhauer, C.N.5    Oppermann, M.6
  • 116
    • 84861744322 scopus 로고    scopus 로고
    • Factor H-related protein 4 activates complement by serving as a platform for the assembly of alternative pathway C3 convertase via its interaction with C3b protein
    • 10.1074/jbc.M112.364471 22518841 1:CAS:528:DC%2BC38XnvVSqt7g%3D
    • Hebecker M, Jozsi M. Factor H-related protein 4 activates complement by serving as a platform for the assembly of alternative pathway C3 convertase via its interaction with C3b protein. J Biol Chem. 2012;287(23):19528-36. doi: 10.1074/jbc.M112.364471.
    • (2012) J Biol Chem , vol.287 , Issue.23 , pp. 19528-19536
    • Hebecker, M.1    Jozsi, M.2
  • 117
    • 20544437666 scopus 로고    scopus 로고
    • Anti-factor H autoantibodies associated with atypical hemolytic uremic syndrome
    • 15590760 1:CAS:528:DC%2BD2MXhvVCkt7g%3D
    • Dragon-Durey M-A, Loirat C, Cloarec S, Macher M-A, Blouin J, Nivet H, et al. Anti-factor H autoantibodies associated with atypical hemolytic uremic syndrome. J Am Soc Nephrol. 2005;16(2):555-63.
    • (2005) J Am Soc Nephrol , vol.16 , Issue.2 , pp. 555-563
    • Dragon-Durey, M.-A.1    Loirat, C.2    Cloarec, S.3    Macher, M.-A.4    Blouin, J.5    Nivet, H.6
  • 118
    • 34548853385 scopus 로고    scopus 로고
    • Anti-factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome
    • 17495132 1:CAS:528:DC%2BD2sXhtVSgsb3P
    • Jozsi M, Strobel S, Dahse H-M, Liu W-S, Hoyer PF, Oppermann M, et al. Anti-factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome. Blood. 2007;110(5):1516-8.
    • (2007) Blood , vol.110 , Issue.5 , pp. 1516-1518
    • Jozsi, M.1    Strobel, S.2    Dahse, H.-M.3    Liu, W.-S.4    Hoyer, P.F.5    Oppermann, M.6
  • 119
    • 84864632060 scopus 로고    scopus 로고
    • Increased IgG on cell-derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation
    • 1:CAS:528:DC%2BC38XmvVygu70%3D
    • Nielsen CT, Østergaard O, Stener L, Iversen LV, Truedsson L, Gullstrand B, et al. Increased IgG on cell-derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation. Arthr Rheum. 2012;64(4):1227-36.
    • (2012) Arthr Rheum , vol.64 , Issue.4 , pp. 1227-1236
    • Nielsen, C.T.1    Østergaard, O.2    Stener, L.3    Iversen, L.V.4    Truedsson, L.5    Gullstrand, B.6
  • 120
    • 84859375702 scopus 로고    scopus 로고
    • Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease
    • 22345666 1:CAS:528:DC%2BC38XksVOltb8%3D
    • Leffler J, Martin M, Gullstrand B, Tyden H, Lood C, Truedsson L, et al. Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease. J Immunol. 2012;188(7):3522-31.
    • (2012) J Immunol , vol.188 , Issue.7 , pp. 3522-3531
    • Leffler, J.1    Martin, M.2    Gullstrand, B.3    Tyden, H.4    Lood, C.5    Truedsson, L.6
  • 121
    • 0037114284 scopus 로고    scopus 로고
    • Concerted clearance of immune complexes bound to the human erythrocyte complement receptor: Development of a heterologous mouse model
    • 12379324 1:CAS:528:DC%2BD38XnvVOntLw%3D
    • Henderson AL, Lindorfer MA, Kennedy AD, Foley PL, Taylor RP. Concerted clearance of immune complexes bound to the human erythrocyte complement receptor: development of a heterologous mouse model. J Immunol Methods. 2002;270(2):183-97.
    • (2002) J Immunol Methods , vol.270 , Issue.2 , pp. 183-197
    • Henderson, A.L.1    Lindorfer, M.A.2    Kennedy, A.D.3    Foley, P.L.4    Taylor, R.P.5
  • 122
    • 0020003845 scopus 로고
    • Complement receptor (CR1) deficiency in erythrocytes from patients with systemic lupus erythematosus
    • 6978375 1:STN:280:DyaL387mvFalsQ%3D%3D
    • Iida K, Mornaghi R, Nussenzweig V. Complement receptor (CR1) deficiency in erythrocytes from patients with systemic lupus erythematosus. J Exp Med. 1982;155(5):1427-38.
    • (1982) J Exp Med , vol.155 , Issue.5 , pp. 1427-1438
    • Iida, K.1    Mornaghi, R.2    Nussenzweig, V.3
  • 123
    • 0035063236 scopus 로고    scopus 로고
    • The complement receptor 3, CR3 (CD11b/CD18), on T lymphocytes: Activation-dependent up-regulation and regulatory function
    • 11298342 1:CAS:528:DC%2BD3MXivFyjs7w%3D
    • Wagner C, Hänsch GM, Stegmaier S, Denefleh B, Hug F, Schoels M. The complement receptor 3, CR3 (CD11b/CD18), on T lymphocytes: activation-dependent up-regulation and regulatory function. Eur J Immunol. 2001;31(4):1173-80.
    • (2001) Eur J Immunol , vol.31 , Issue.4 , pp. 1173-1180
    • Wagner, C.1    Hänsch, G.M.2    Stegmaier, S.3    Denefleh, B.4    Hug, F.5    Schoels, M.6
  • 124
    • 0028130314 scopus 로고
    • Identification of the complement iC3b binding site in the beta 2 integrin CR3 (CD11b/CD18)
    • 7524101 1:CAS:528:DyaK2MXhsleltrY%3D
    • Ueda T, Rieu P, Brayer J, Arnaout MA. Identification of the complement iC3b binding site in the beta 2 integrin CR3 (CD11b/CD18). Proc Natl Acad Sci USA. 1994;91(22):10680-4.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.22 , pp. 10680-10684
    • Ueda, T.1    Rieu, P.2    Brayer, J.3    Arnaout, M.A.4
  • 125
    • 38649108122 scopus 로고    scopus 로고
    • A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus
    • 18204448 1:CAS:528:DC%2BD1cXhtl2kuro%3D
    • Nath SK, Han S, Kim-Howard X, Kelly JA, Viswanathan P, Gilkeson GS, et al. A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus. Nat Genet. 2008;40(2):152-4.
    • (2008) Nat Genet , vol.40 , Issue.2 , pp. 152-154
    • Nath, S.K.1    Han, S.2    Kim-Howard, X.3    Kelly, J.A.4    Viswanathan, P.5    Gilkeson, G.S.6
  • 126
    • 77954995416 scopus 로고    scopus 로고
    • ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry
    • 19939855
    • Kim-Howard X, Maiti AK, Anaya J-M, Bruner GR, Brown E, Merrill JT, et al. ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry. Ann Rheum Dis. 2010;69(7):1329-32.
    • (2010) Ann Rheum Dis , vol.69 , Issue.7 , pp. 1329-1332
    • Kim-Howard, X.1    Maiti, A.K.2    Anaya, J.-M.3    Bruner, G.R.4    Brown, E.5    Merrill, J.T.6
  • 127
    • 7844248266 scopus 로고    scopus 로고
    • IgM anti-dsDNA antibodies in systemic lupus erythematosus: Negative association with nephritis
    • 9833247 1:STN:280:DyaK1M%2FltVCnsw%3D%3D
    • Witte T, Hartung K, Sachse C, Matthias T, Fricke M, Deicher H, et al. IgM anti-dsDNA antibodies in systemic lupus erythematosus: negative association with nephritis. Rheumatol Int. 1998;18(3):85-91.
    • (1998) Rheumatol Int , vol.18 , Issue.3 , pp. 85-91
    • Witte, T.1    Hartung, K.2    Sachse, C.3    Matthias, T.4    Fricke, M.5    Deicher, H.6
  • 128
    • 0023881251 scopus 로고
    • Surface expression of Gp 165/95, the complement receptor CR3, as a marker of disease activity in systemic lupus erythematosus
    • 2961492 1:STN:280:DyaL1c%2FotFSqtw%3D%3D
    • Buyon JP, Shadick N, Berkman R, Hopkins P, Dalton J, Weissmann G, et al. Surface expression of Gp 165/95, the complement receptor CR3, as a marker of disease activity in systemic lupus erythematosus. Clin Immunol Immunopathol. 1988;46:141-9.
    • (1988) Clin Immunol Immunopathol , vol.46 , pp. 141-149
    • Buyon, J.P.1    Shadick, N.2    Berkman, R.3    Hopkins, P.4    Dalton, J.5    Weissmann, G.6
  • 129
    • 79251544880 scopus 로고    scopus 로고
    • Complement alternative pathway acts as a positive feedback amplification of neutrophil activation
    • 21063021 1:CAS:528:DC%2BC3MXhvFGksL0%3D
    • Camous L, Roumenina L, Bigot S, Brachemi S, Fremeaux-Bacchi V, Lesavre P, et al. Complement alternative pathway acts as a positive feedback amplification of neutrophil activation. Blood. 2011;117(4):1340-9.
    • (2011) Blood , vol.117 , Issue.4 , pp. 1340-1349
    • Camous, L.1    Roumenina, L.2    Bigot, S.3    Brachemi, S.4    Fremeaux-Bacchi, V.5    Lesavre, P.6
  • 130
    • 0023795109 scopus 로고
    • Synergistic interaction between complement receptor type 2 and membrane IgM on B lymphocytes
    • 2968402 1:CAS:528:DyaL1cXkvFWjtb0%3D
    • Carter RH, Spycher MO, Ng YC, Hoffman R, Fearon DT. Synergistic interaction between complement receptor type 2 and membrane IgM on B lymphocytes. J Immunol. 1988;141(2):457-63.
    • (1988) J Immunol , vol.141 , Issue.2 , pp. 457-463
    • Carter, R.H.1    Spycher, M.O.2    Ng, Y.C.3    Hoffman, R.4    Fearon, D.T.5
  • 131
    • 0034252626 scopus 로고    scopus 로고
    • C3d enhancement of antibodies to hemagglutinin accelerates protection against influenza virus challenge
    • 11248804 1:CAS:528:DC%2BD3cXlsFOmurw%3D
    • Ross TM, Xu Y, Bright RA, Robinson HL. C3d enhancement of antibodies to hemagglutinin accelerates protection against influenza virus challenge. Nat Immunol. 2000;1(2):127-31.
    • (2000) Nat Immunol , vol.1 , Issue.2 , pp. 127-131
    • Ross, T.M.1    Xu, Y.2    Bright, R.A.3    Robinson, H.L.4
  • 132
    • 29144503991 scopus 로고    scopus 로고
    • Complement component C3d-antigen complexes can either augment or inhibit B lymphocyte activation and humoral immunity in mice depending on the degree of CD21/CD19 complex engagement
    • 16339538 1:CAS:528:DC%2BD2MXht12jt77E
    • Lee Y, Haas KM, Gor DO, Ding X, Karp DR, Greenspan NS, et al. Complement component C3d-antigen complexes can either augment or inhibit B lymphocyte activation and humoral immunity in mice depending on the degree of CD21/CD19 complex engagement. J Immunol. 2005;175(12):8011-23.
    • (2005) J Immunol , vol.175 , Issue.12 , pp. 8011-8023
    • Lee, Y.1    Haas, K.M.2    Gor, D.O.3    Ding, X.4    Karp, D.R.5    Greenspan, N.S.6
  • 133
    • 0036165616 scopus 로고    scopus 로고
    • Depletion of Lyn kinase from the BCR complex and inhibition of B cell activation by excess CD21 ligation
    • 11809733 1:CAS:528:DC%2BD38Xht1Cmt78%3D
    • Chakravarty L, Zabel MD, Weis JJ, Weis JH. Depletion of Lyn kinase from the BCR complex and inhibition of B cell activation by excess CD21 ligation. Int Immunol. 2002;14(2):139-46.
    • (2002) Int Immunol , vol.14 , Issue.2 , pp. 139-146
    • Chakravarty, L.1    Zabel, M.D.2    Weis, J.J.3    Weis, J.H.4
  • 134
    • 77951900825 scopus 로고    scopus 로고
    • Innate and adaptive receptors interact to balance humoral immunity
    • 20164432 1:CAS:528:DC%2BC3cXitV2lu7k%3D
    • Tedder TF. Innate and adaptive receptors interact to balance humoral immunity. J Immunol. 2010;184(5):2231-2.
    • (2010) J Immunol , vol.184 , Issue.5 , pp. 2231-2232
    • Tedder, T.F.1
  • 135
    • 0032211714 scopus 로고    scopus 로고
    • A critical role for complement in maintenance of self-tolerance
    • 9846493 1:CAS:528:DyaK1cXnvFWrs70%3D
    • Prodeus AP, Goerg S, Shen L-M, Pozdnyakova OO, Chu L, Alicot EM, et al. A critical role for complement in maintenance of self-tolerance. Immunity. 1998;9(5):721-31.
    • (1998) Immunity , vol.9 , Issue.5 , pp. 721-731
    • Prodeus, A.P.1    Goerg, S.2    Shen, L.-M.3    Pozdnyakova, O.O.4    Chu, L.5    Alicot, E.M.6
  • 136
    • 0036681645 scopus 로고    scopus 로고
    • A role for the Cr2 gene in modifying autoantibody production in systemic lupus erythematosus
    • 12133988 1:CAS:528:DC%2BD38XlslWhtLY%3D
    • Wu X, Jiang N, Deppong C, Singh J, Dolecki G, Mao D, et al. A role for the Cr2 gene in modifying autoantibody production in systemic lupus erythematosus. J Immunol. 2002;169(3):1587-92.
    • (2002) J Immunol , vol.169 , Issue.3 , pp. 1587-1592
    • Wu, X.1    Jiang, N.2    Deppong, C.3    Singh, J.4    Dolecki, G.5    Mao, D.6
  • 137
    • 0035652286 scopus 로고    scopus 로고
    • Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein
    • 11728339 1:CAS:528:DC%2BD3MXptVGgtb0%3D
    • Boackle SA, Holers VM, Chen X, Szakonyi G, Karp DR, Wakeland EK, et al. Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein. Immunity. 2001;15(5):775-85.
    • (2001) Immunity , vol.15 , Issue.5 , pp. 775-785
    • Boackle, S.A.1    Holers, V.M.2    Chen, X.3    Szakonyi, G.4    Karp, D.R.5    Wakeland, E.K.6
  • 138
    • 33947626703 scopus 로고    scopus 로고
    • Augmentation of NZB autoimmune phenotypes by the Sle1c murine lupus susceptibility interval
    • 17372026 1:CAS:528:DC%2BD2sXjt1Wksb4%3D
    • Giles BM, Tchepeleva SN, Kachinski JJ, Ruff K, Croker BP, Morel L, et al. Augmentation of NZB autoimmune phenotypes by the Sle1c murine lupus susceptibility interval. J Immunol. 2007;178(7):4667-75.
    • (2007) J Immunol , vol.178 , Issue.7 , pp. 4667-4675
    • Giles, B.M.1    Tchepeleva, S.N.2    Kachinski, J.J.3    Ruff, K.4    Croker, B.P.5    Morel, L.6
  • 139
    • 84857802310 scopus 로고    scopus 로고
    • Genetic CD21 deficiency is associated with hypogammaglobulinemia
    • 22035880 1:CAS:528:DC%2BC38XjsVSqsbo%3D
    • Thiel J, Kimmig L, Salzer U, Grudzien M, Lebrecht D, Hagena T, et al. Genetic CD21 deficiency is associated with hypogammaglobulinemia. J Allergy Clin Immunol. 2012;129(3):801-10.
    • (2012) J Allergy Clin Immunol , vol.129 , Issue.3 , pp. 801-810
    • Thiel, J.1    Kimmig, L.2    Salzer, U.3    Grudzien, M.4    Lebrecht, D.5    Hagena, T.6
  • 140
    • 34247239760 scopus 로고    scopus 로고
    • Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus
    • 17360460 1:CAS:528:DC%2BD2sXjtlaisbg%3D
    • Wu H, Boackle SA, Hanvivadhanakul P, Ulgiati D, Grossman JM, Lee Y, et al. Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus. Proc Natl Acad Sci USA. 2007;104(10):3961-6.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.10 , pp. 3961-3966
    • Wu, H.1    Boackle, S.A.2    Hanvivadhanakul, P.3    Ulgiati, D.4    Grossman, J.M.5    Lee, Y.6
  • 141
    • 67849133217 scopus 로고    scopus 로고
    • Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing
    • 19387458 1:CAS:528:DC%2BD1MXptVaru7k%3D
    • Douglas KB, Windels DC, Zhao J, Gadeliya AV, Wu H, Kaufman KM, et al. Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing. Genes Immun. 2009;10(5):457-69.
    • (2009) Genes Immun , vol.10 , Issue.5 , pp. 457-469
    • Douglas, K.B.1    Windels, D.C.2    Zhao, J.3    Gadeliya, A.V.4    Wu, H.5    Kaufman, K.M.6
  • 142
    • 0031035199 scopus 로고    scopus 로고
    • Follicular dendritic cells specifically express the long CR2/CD21 isoform
    • 10.1084/jem.185.1.165 8996252 1:CAS:528:DyaK2sXjvF2jsg%3D%3D
    • Liu Y-J, Xu J, de Bouteiller O, Parham CL, Grouard G, Djossou O, et al. Follicular dendritic cells specifically express the long CR2/CD21 isoform. J Exp Med. 1997;185(1):165-70. doi: 10.1084/jem.185.1.165.
    • (1997) J Exp Med , vol.185 , Issue.1 , pp. 165-170
    • Liu, Y.-J.1    Xu, J.2    De Bouteiller, O.3    Parham, C.L.4    Grouard, G.5    Djossou, O.6
  • 143
    • 40449119706 scopus 로고    scopus 로고
    • Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice
    • 18178863 1:CAS:528:DC%2BD1cXhsVOqtA%3D%3D
    • Atkinson C, Qiao F, Song H, Gilkeson GS, Tomlinson S. Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice. J Immunol. 2008;180(2):1231-8.
    • (2008) J Immunol , vol.180 , Issue.2 , pp. 1231-1238
    • Atkinson, C.1    Qiao, F.2    Song, H.3    Gilkeson, G.S.4    Tomlinson, S.5
  • 144
    • 79953729061 scopus 로고    scopus 로고
    • The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice
    • 1:CAS:528:DC%2BC3MXmt1Orurs%3D
    • Sekine H, Kinser TTH, Qiao F, Martinez E, Paulling E, Ruiz P, et al. The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice. Arthr Rheum. 2011;63(4):1076-85.
    • (2011) Arthr Rheum , vol.63 , Issue.4 , pp. 1076-1085
    • Sekine, H.1    Kinser, T.T.H.2    Qiao, F.3    Martinez, E.4    Paulling, E.5    Ruiz, P.6


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