메뉴 건너뛰기




Volumn 28, Issue 2, 2006, Pages 175-184

Molecular and cellular basis for pathogenicity of autoantibodies: Lessons from murine monoclonal autoantibodies

Author keywords

Autoimmune hemolytic anemia; Complement; Cryoglobulin; IgG Fc receptor; IgG glycosylation; SLE

Indexed keywords

AUTOANTIBODY; COMPLEMENT; FC RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G3; MONOCLONAL ANTIBODY;

EID: 34247368484     PISSN: 03444325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00281-006-0037-0     Document Type: Review
Times cited : (82)

References (68)
  • 4
    • 0036009179 scopus 로고    scopus 로고
    • FcγRI-deficient mice show multiple alterations to inflammatory and immune responses
    • Barnes N, Gavin AL, Tan PS, Mottram P, Koentgen F, Hogarth PM (2002) FcγRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 16:379-389
    • (2002) Immunity , vol.16 , pp. 379-389
    • Barnes, N.1    Gavin, A.L.2    Tan, P.S.3    Mottram, P.4    Koentgen, F.5    Hogarth, P.M.6
  • 6
    • 0016262898 scopus 로고
    • Biological and clinical significance of cryoglobulins. A report of 86 cases
    • Brouet JC, Clauvel JP, Danon F, Klein M, Seligmann M (1974) Biological and clinical significance of cryoglobulins. A report of 86 cases. Am J Med 57:775-788
    • (1974) Am J Med , vol.57 , pp. 775-788
    • Brouet, J.C.1    Clauvel, J.P.2    Danon, F.3    Klein, M.4    Seligmann, M.5
  • 7
    • 0024562305 scopus 로고
    • Characterization of the spontaneous autoimmune (anti-erythrocyte) response in NZB mice using a pathogenic monoclonal autoantibody and its anti-idiotype
    • Caulfield MJ, Stanko D, Calkins C (1989) Characterization of the spontaneous autoimmune (anti-erythrocyte) response in NZB mice using a pathogenic monoclonal autoantibody and its anti-idiotype. Immunology 66:233-237
    • (1989) Immunology , vol.66 , pp. 233-237
    • Caulfield, M.J.1    Stanko, D.2    Calkins, C.3
  • 8
    • 0032512855 scopus 로고    scopus 로고
    • Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis
    • Clynes R, Dumitru C, Ravetch JV (1998) Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. Science 279:1052-1054
    • (1998) Science , vol.279 , pp. 1052-1054
    • Clynes, R.1    Dumitru, C.2    Ravetch, J.V.3
  • 9
    • 0033521604 scopus 로고    scopus 로고
    • Modulation of immune complex-induced inflammation in vivo by the coordinate expressison of activation and inhibitory Fc receptors
    • Clynes R, Maizes JS, Guinamard R, Ono M, Takai T, Ravetch JV (1999) Modulation of immune complex-induced inflammation in vivo by the coordinate expressison of activation and inhibitory Fc receptors. J Exp Med 189:179-185
    • (1999) J Exp Med , vol.189 , pp. 179-185
    • Clynes, R.1    Maizes, J.S.2    Guinamard, R.3    Ono, M.4    Takai, T.5    Ravetch, J.V.6
  • 10
    • 0037087262 scopus 로고    scopus 로고
    • α-Actinin is a cross-reactive renal target for pathogenic anti-DNA antibodies
    • Deocharan B, Qing X, Lichauco J, Putterman C (2002) α-Actinin is a cross-reactive renal target for pathogenic anti-DNA antibodies. J Immunol 168:3072-3078
    • (2002) J Immunol , vol.168 , pp. 3072-3078
    • Deocharan, B.1    Qing, X.2    Lichauco, J.3    Putterman, C.4
  • 11
    • 0023897194 scopus 로고
    • The binding site for C1q on IgG
    • Duncan AR, Winter G (1988) The binding site for C1q on IgG. Nature 332:738-740
    • (1988) Nature , vol.332 , pp. 738-740
    • Duncan, A.R.1    Winter, G.2
  • 12
    • 0023933120 scopus 로고
    • Localization of the binding site for the human high-affinity Fc receptor on IgG
    • Duncan AR, Woof JM, Partridge LJ, Burton DR, Winter G (1988) Localization of the binding site for the human high-affinity Fc receptor on IgG. Nature 332:563-564
    • (1988) Nature , vol.332 , pp. 563-564
    • Duncan, A.R.1    Woof, J.M.2    Partridge, L.J.3    Burton, D.R.4    Winter, G.5
  • 13
    • 0007773119 scopus 로고
    • Regulation of the amplification C3 convertase of human complement by an inhibitory protein isolated from human erythrocyte membrane
    • Fearon DT (1979) Regulation of the amplification C3 convertase of human complement by an inhibitory protein isolated from human erythrocyte membrane. Proc Natl Acad Sci USA 76:5867-5871
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 5867-5871
    • Fearon, D.T.1
  • 14
    • 0027930909 scopus 로고
    • Interleukin 6 promotes murine lupus in NZB/NZW F1 mice
    • Finck BK, Chan B, Wofsy D (1994) Interleukin 6 promotes murine lupus in NZB/NZW F1 mice. J Clin Invest 94:585-591
    • (1994) J Clin Invest , vol.94 , pp. 585-591
    • Finck, B.K.1    Chan, B.2    Wofsy, D.3
  • 17
    • 0027531961 scopus 로고
    • Immunoglobulin heavy chain constant region determines the pathogenicity and the antigen-binding activity of rheumatoid factor
    • Fulpius T, Spertini F, Reininger L, Izui S (1993) Immunoglobulin heavy chain constant region determines the pathogenicity and the antigen-binding activity of rheumatoid factor. Proc Natl Acad Sci USA 90:2345-2349
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2345-2349
    • Fulpius, T.1    Spertini, F.2    Reininger, L.3    Izui, S.4
  • 18
    • 0029862692 scopus 로고    scopus 로고
    • Polymorphonuclear leukocytes play a key role in the generation of "wire-loop" lesions induced by a murine IgG3 rheumatoid factor
    • Fulpius T, Lemoine R, Berney T, Pastore Y, Moll S, Izui S (1996) Polymorphonuclear leukocytes play a key role in the generation of "wire-loop" lesions induced by a murine IgG3 rheumatoid factor. Kidney Int 49:647-655
    • (1996) Kidney Int , vol.49 , pp. 647-655
    • Fulpius, T.1    Lemoine, R.2    Berney, T.3    Pastore, Y.4    Moll, S.5    Izui, S.6
  • 23
    • 0028081880 scopus 로고
    • Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice
    • Ishida H, Muchamuel T, Sakaguchi S, Andrade S, Menon S, Howard M (1994) Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice. J Exp Med 179:305-310
    • (1994) J Exp Med , vol.179 , pp. 305-310
    • Ishida, H.1    Muchamuel, T.2    Sakaguchi, S.3    Andrade, S.4    Menon, S.5    Howard, M.6
  • 24
    • 0027743353 scopus 로고
    • Induction of different types of glomerulonephritis by monoclonal antibodies derived from an MRL/lpr lupus mouse
    • Itoh J, Nose M, Takahashi S, Ono M, Terasaki S, Kondoh E, Kyogoku M (1993) Induction of different types of glomerulonephritis by monoclonal antibodies derived from an MRL/lpr lupus mouse. Am J Pathol 143:1436-1443
    • (1993) Am J Pathol , vol.143 , pp. 1436-1443
    • Itoh, J.1    Nose, M.2    Takahashi, S.3    Ono, M.4    Terasaki, S.5    Kondoh, E.6    Kyogoku, M.7
  • 25
    • 0019453067 scopus 로고
    • Retroviral gp70 immune complexes in NZBxNZW F2 mice with murine lupus nephritis
    • Izui S, McConahey PJ, Clark JP, Hang LM, Hara I, Dixon FJ (1981) Retroviral gp70 immune complexes in NZBxNZW F2 mice with murine lupus nephritis. J Exp Med 154:517-528
    • (1981) J Exp Med , vol.154 , pp. 517-528
    • Izui, S.1    McConahey, P.J.2    Clark, J.P.3    Hang, L.M.4    Hara, I.5    Dixon, F.J.6
  • 29
    • 33645080442 scopus 로고    scopus 로고
    • Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors
    • Kaneko Y, Nimmerjahn F, Madaio MP, Ravetch JV (2006) Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors. J Exp Med 203:789-797
    • (2006) J Exp Med , vol.203 , pp. 789-797
    • Kaneko, Y.1    Nimmerjahn, F.2    Madaio, M.P.3    Ravetch, J.V.4
  • 31
    • 23244454433 scopus 로고    scopus 로고
    • A critical role for sialylation in cryoglobulin activity of murine IgG3 monoclonal antibodies
    • Kuroda Y, Kuroki A, Kikuchi S, Funase T, Nakata M, Izui S (2005) A critical role for sialylation in cryoglobulin activity of murine IgG3 monoclonal antibodies. J Immunol 175:1056-1061
    • (2005) J Immunol , vol.175 , pp. 1056-1061
    • Kuroda, Y.1    Kuroki, A.2    Kikuchi, S.3    Funase, T.4    Nakata, M.5    Izui, S.6
  • 33
    • 0036008486 scopus 로고    scopus 로고
    • Interaction of CD22 with α2,6-linked sialoglycoconjugates: Innate recognition of self to dampen B cell autoreactivity?
    • Lanoue A, Batista FD, Stewart M, Neuberger MS (2002) Interaction of CD22 with α2,6-linked sialoglycoconjugates: innate recognition of self to dampen B cell autoreactivity? Eur J Immunol 32:348-355
    • (2002) Eur J Immunol , vol.32 , pp. 348-355
    • Lanoue, A.1    Batista, F.D.2    Stewart, M.3    Neuberger, M.S.4
  • 35
    • 0030470557 scopus 로고    scopus 로고
    • Multiple interactions of IgG with its core oligosaccharide can modulate recognition by complement and human Fcγ receptor I and influence the synthesis of its oligosaccharide chains
    • Lund J, Takahashi N, Pound JD, Goodall M, Jefferis R (1996) Multiple interactions of IgG with its core oligosaccharide can modulate recognition by complement and human Fcγ receptor I and influence the synthesis of its oligosaccharide chains. J Immunol 157:4963-4969
    • (1996) J Immunol , vol.157 , pp. 4963-4969
    • Lund, J.1    Takahashi, N.2    Pound, J.D.3    Goodall, M.4    Jefferis, R.5
  • 36
    • 0028962403 scopus 로고
    • Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein
    • Malhotra R, Wormald MR, Rudd PM, Fischer PB, Dwek RA, Sim RB (1995) Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein. Nature Med 1:237-243
    • (1995) Nature Med , vol.1 , pp. 237-243
    • Malhotra, R.1    Wormald, M.R.2    Rudd, P.M.3    Fischer, P.B.4    Dwek, R.A.5    Sim, R.B.6
  • 38
    • 0028158771 scopus 로고
    • Anticardiolipin antibodies recognize β2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface
    • Matsuura E, Igarashi Y, Yasuda T, Triplett DA, Koike T (1994) Anticardiolipin antibodies recognize β2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface. J Exp Med 179:457-462
    • (1994) J Exp Med , vol.179 , pp. 457-462
    • Matsuura, E.1    Igarashi, Y.2    Yasuda, T.3    Triplett, D.A.4    Koike, T.5
  • 39
    • 0037093245 scopus 로고    scopus 로고
    • Crry, but not CD59 and DAF, is indispensable for murine erythrocyte protection in vivo from spontaneous complement attack
    • Miwa T, Zhou L, Hilliard B, Molina H, Song WC (2002) Crry, but not CD59 and DAF, is indispensable for murine erythrocyte protection in vivo from spontaneous complement attack. Blood 99:3707-3716
    • (2002) Blood , vol.99 , pp. 3707-3716
    • Miwa, T.1    Zhou, L.2    Hilliard, B.3    Molina, H.4    Song, W.C.5
  • 40
    • 0025038766 scopus 로고
    • Structural changes in the oligosaccharide chains of IgG in autoimmune MRL/Mp-lpr/lpr mice
    • Mizuochi T, Hamako J, Nose M, Titani K (1990) Structural changes in the oligosaccharide chains of IgG in autoimmune MRL/Mp-lpr/lpr mice. J Immunol 145:1794-1798
    • (1990) J Immunol , vol.145 , pp. 1794-1798
    • Mizuochi, T.1    Hamako, J.2    Nose, M.3    Titani, K.4
  • 42
    • 0037114618 scopus 로고    scopus 로고
    • Complement-mediated clearance of erythrocytes: Mechanism and delineation of the regulatory roles of Crry and DAF. Decay-accelerating factor
    • Molina H, Miwa T, Zhou L, Hilliard B, Mastellos D, Maldonado MA, Lambris JD, Song WC (2002) Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF. Decay-accelerating factor. Blood 100:4544-4549
    • (2002) Blood , vol.100 , pp. 4544-4549
    • Molina, H.1    Miwa, T.2    Zhou, L.3    Hilliard, B.4    Mastellos, D.5    Maldonado, M.A.6    Lambris, J.D.7    Song, W.C.8
  • 45
    • 28544449847 scopus 로고    scopus 로고
    • Divergent immunoglobulin-G subclass activity through selective Fc receptor binding
    • Nimmerjahn F, Ravetch JV (2005) Divergent immunoglobulin-G subclass activity through selective Fc receptor binding. Science 310:1510-1512
    • (2005) Science , vol.310 , pp. 1510-1512
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 46
    • 30444461383 scopus 로고    scopus 로고
    • Fcγ receptors: Old friends and new family members
    • Nimmerjahn F, Ravetch JV (2006) Fcγ receptors: old friends and new family members. Immunity 24:19-28
    • (2006) Immunity , vol.24 , pp. 19-28
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 47
    • 22544487815 scopus 로고    scopus 로고
    • FcγRIV: A novel FcR with distinct IgG subclass specificity
    • Nimmerjahn F, Bruhns P, Horiuchi K, Ravetch JV (2005) FcγRIV: a novel FcR with distinct IgG subclass specificity. Immunity 23:41-51
    • (2005) Immunity , vol.23 , pp. 41-51
    • Nimmerjahn, F.1    Bruhns, P.2    Horiuchi, K.3    Ravetch, J.V.4
  • 48
    • 0028818501 scopus 로고
    • Administration of interleukin-5 or -10 activates B-1 cells and induces autoimmune hemolytic anemia in anti-erythrocyte autoantibodytransgenic mice
    • Nisitani S, Tsubata T, Murakami M, Honjo T (1995) Administration of interleukin-5 or -10 activates B-1 cells and induces autoimmune hemolytic anemia in anti-erythrocyte autoantibodytransgenic mice. Eur J Immunol 25:3047-3052
    • (1995) Eur J Immunol , vol.25 , pp. 3047-3052
    • Nisitani, S.1    Tsubata, T.2    Murakami, M.3    Honjo, T.4
  • 51
    • 0037117557 scopus 로고    scopus 로고
    • T-bet regulates IgG class switching and pathogenic autoantibody production
    • Peng SL, Szabo SJ, Glimcher LH (2002) T-bet regulates IgG class switching and pathogenic autoantibody production. Proc Natl Acad Sci USA 99:5545-5550
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5545-5550
    • Peng, S.L.1    Szabo, S.J.2    Glimcher, L.H.3
  • 53
    • 0025599440 scopus 로고
    • Cryoglobulinemia induced by a murine IgG3 rheumatoid factor: Skin vasculitis and glomerulonephritis arise from distinct pathogenic mechanisms
    • Reininger L, Berney T, Shibata T, Spertini F, Merino R, Izui S (1990) Cryoglobulinemia induced by a murine IgG3 rheumatoid factor: Skin vasculitis and glomerulonephritis arise from distinct pathogenic mechanisms. Proc Natl Acad Sci USA 87:10038-10042
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 10038-10042
    • Reininger, L.1    Berney, T.2    Shibata, T.3    Spertini, F.4    Merino, R.5    Izui, S.6
  • 54
    • 0035910392 scopus 로고    scopus 로고
    • Anti-inflammatory activity of IVIG mediated through the inhibitory receptor
    • Samuelsson A, Towers TL, Ravetch JV (2001) Anti-inflammatory activity of IVIG mediated through the inhibitory receptor. Science 291:484-486
    • (2001) Science , vol.291 , pp. 484-486
    • Samuelsson, A.1    Towers, T.L.2    Ravetch, J.V.3
  • 55
  • 57
    • 0025676294 scopus 로고
    • Monoclonal anti-erythrocyte autoantibodies derived from NZB mice cause autoimmune hemolytic anemia by two distinct pathogenic mechanisms
    • Shibata T, Berney T, Reininger L, Chicheportiche Y, Ozaki S, Shirai T, Izui S (1990) Monoclonal anti-erythrocyte autoantibodies derived from NZB mice cause autoimmune hemolytic anemia by two distinct pathogenic mechanisms. Int Immunol 2:1133-1141
    • (1990) Int Immunol , vol.2 , pp. 1133-1141
    • Shibata, T.1    Berney, T.2    Reininger, L.3    Chicheportiche, Y.4    Ozaki, S.5    Shirai, T.6    Izui, S.7
  • 58
    • 0030458140 scopus 로고    scopus 로고
    • Immunoglobulin G-mediated inflammatory responses develop normally in complement deficient mice
    • Sylvestre DL, Clynes R, Ma M, Warren H, Carroll MC, Ravetch JV (1996) Immunoglobulin G-mediated inflammatory responses develop normally in complement deficient mice. J Exp Med 184:2385-2392
    • (1996) J Exp Med , vol.184 , pp. 2385-2392
    • Sylvestre, D.L.1    Clynes, R.2    Ma, M.3    Warren, H.4    Carroll, M.C.5    Ravetch, J.V.6
  • 59
    • 0025886306 scopus 로고
    • IgG3 production in MRL/lpr mice is responsible for development of lupus nephritis
    • Takahashi S, Nose M, Sasaki J, Yamamoto T, Kyogoku M (1991) IgG3 production in MRL/lpr mice is responsible for development of lupus nephritis. J Immunol 147:515-519
    • (1991) J Immunol , vol.147 , pp. 515-519
    • Takahashi, S.1    Nose, M.2    Sasaki, J.3    Yamamoto, T.4    Kyogoku, M.5
  • 60
    • 0027391808 scopus 로고
    • Cloning and cDNA sequence analysis of nephritogenic monoclonal antibodies derived from an MRL/lpr lupus mouse
    • Takahashi S, Itoh J, Nose M, Ono M, Yamamoto T, Kyogoku M (1993) Cloning and cDNA sequence analysis of nephritogenic monoclonal antibodies derived from an MRL/lpr lupus mouse. Mol Immunol 30:177-182
    • (1993) Mol Immunol , vol.30 , pp. 177-182
    • Takahashi, S.1    Itoh, J.2    Nose, M.3    Ono, M.4    Yamamoto, T.5    Kyogoku, M.6
  • 61
    • 0029928187 scopus 로고    scopus 로고
    • Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice
    • Takahashi S, Fossati L, Iwamoto M, Merino R, Motta R, Kobayakawa T, Izui S (1996) Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice. J Clin Invest 97:1597-1604
    • (1996) J Clin Invest , vol.97 , pp. 1597-1604
    • Takahashi, S.1    Fossati, L.2    Iwamoto, M.3    Merino, R.4    Motta, R.5    Kobayakawa, T.6    Izui, S.7
  • 62
    • 0036676975 scopus 로고    scopus 로고
    • Roles of Fc receptors in autoimmunity
    • Takai T (2002) Roles of Fc receptors in autoimmunity. Nat Rev Immunol 2:580-592
    • (2002) Nat Rev Immunol , vol.2 , pp. 580-592
    • Takai, T.1
  • 63
    • 0030031886 scopus 로고    scopus 로고
    • Augmented humoral and anaphylactic responses in FcγRII-deficient mice
    • Takai T, Ono M, Hikida M, Ohmori H, Ravetch JV (1996) Augmented humoral and anaphylactic responses in FcγRII-deficient mice. Nature 379:346-349
    • (1996) Nature , vol.379 , pp. 346-349
    • Takai, T.1    Ono, M.2    Hikida, M.3    Ohmori, H.4    Ravetch, J.V.5
  • 64
    • 0030784483 scopus 로고    scopus 로고
    • A role of Mac-1(CD11b/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcγ receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis
    • Tang T, Rosenkranz A, Assmann KJM, Goodman MJ, Gutierrez-Ramos JC, Carroll MC, Cotran RS, Mayadas TN (1997) A role of Mac-1(CD11b/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcγ receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis. J Exp Med 186:1853-1863
    • (1997) J Exp Med , vol.186 , pp. 1853-1863
    • Tang, T.1    Rosenkranz, A.2    Assmann, K.J.M.3    Goodman, M.J.4    Gutierrez-Ramos, J.C.5    Carroll, M.C.6    Cotran, R.S.7    Mayadas, T.N.8
  • 67
    • 0029764359 scopus 로고    scopus 로고
    • Amelioration of lupus-like autoimmune disease in NZB/W F1 mice after treatment with a blocking monoclonal antibody specific for complement component C5
    • Wang Y, Hu Q, Madri JA, Rollins SA, Chodera A, Matis LA (1996) Amelioration of lupus-like autoimmune disease in NZB/W F1 mice after treatment with a blocking monoclonal antibody specific for complement component C5. Proc Natl Acad Sci USA 93:8563-8568
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8563-8568
    • Wang, Y.1    Hu, Q.2    Madri, J.A.3    Rollins, S.A.4    Chodera, A.5    Matis, L.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.