An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

Human Molecular Genetics

Volumn 19, Issue 23, 2010, Pages 4694-4704

  Fritsche, Lars G ^a   Lauer, Nadine ^b   Hartmann, Andrea ^b   Stippa, Selina ^b   Keilhauer, Claudia N ^c   Oppermann, Martin ^d   Pandey, Manoj K ^e   Köhl, Jörg ^e,f   Zipfel, Peter F ^b,g   Weber, Bernhard H F ^a   Skerka, Christine ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b HANS KNÖLL INSTITUTE   (Germany)

^c UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

^e CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^f UNIVERSITY OF LÜBECK   (Germany)

^g FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C5A; COMPLEMENT FACTOR H; PROTEIN CFHR1; PROTEIN CFHR3; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; GERMANY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RETINA MACULA AGE RELATED DEGENERATION;

AGED; AGED, 80 AND OVER; BLOOD PROTEINS; BLOTTING, WESTERN; COMPLEMENT C3-C5 CONVERTASES; COMPLEMENT C3B INACTIVATOR PROTEINS; COMPLEMENT C5A; COMPLEMENT FACTOR H; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE DELETION; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MACULAR DEGENERATION; MIDDLE AGED; NEUTROPHILS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 78149270873     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq399     Document Type: Article

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