Inhibition of Nuclear Factor-Kappa B Activation Decreases Survival of Mycobacterium tuberculosis in Human Macrophages

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Bai, Xiyuan ^a,b,c   Feldman, Nicole E ^b   Chmura, Kathryn ^b,c   Ovrutsky, Alida R ^b,c   Su, Wen Lin ^e   Griffin, Laura ^c   Pyeon, Dohun ^c   McGibney, Mischa T ^b   Strand, Matthew J ^b   Numata, Mari ^b   Murakami, Seiji ^b   Gaido, Loretta ^d   Honda, Jennifer R ^b,c   Kinney, William H ^b,c   Oberley Deegan, Rebecca E ^b   Voelker, Dennis R ^b   Ordway, Diane J ^f   Chan, Edward D ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b DEPARTMENT OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d DENVER HEALTH MEDICAL CENTER   (United States)

^e TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^f Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; CASPASE 3; GAMMA INTERFERON; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; 3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE; CASPASE INHIBITOR; NITRILE; SULFONE;

APOPTOSIS; ARTICLE; AUTOPHAGY; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIAL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INHIBITION; GROWTH INHIBITION; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INTRACELLULAR SIGNALING; MACROPHAGE; MACROPHAGE FUNCTION; MYCOBACTERIUM TUBERCULOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; ADENOVIRIDAE; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; INTRACELLULAR SPACE; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; PHYSIOLOGY;

ADENOVIRIDAE; CORYNEBACTERINEAE; MUS; MYCOBACTERIUM TUBERCULOSIS;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; AUTOPHAGY; CASPASE 3; CASPASE INHIBITORS; CELL LINE; HUMANS; INTRACELLULAR SPACE; MACROPHAGES; MICROBIAL VIABILITY; MYCOBACTERIUM TUBERCULOSIS; NF-KAPPA B; NITRILES; SULFONES;

EID: 84876734256     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061925     Document Type: Article

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