The Mycobacterium tuberculosis early secreted antigenic target of 6 kDa inhibits T cell interferon-γ production through the p38 mitogen-activated protein kinase Pathway

Journal of Biological Chemistry

Volumn 286, Issue 27, 2011, Pages 24508-24518

  Peng, Hui ^a,c   Wang, Xisheng ^a   Barnes, Peter F ^a,b   Tang, Hua ^a   Townsend, James C ^a,d   Samten, Buka ^a  

^a UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^b Health Science Center   (United States)

^c SUN YAT SEN UNIVERSITY   (China)

^d CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOSE-DEPENDENT MANNER; HUMAN T CELLS; MYCOBACTERIUM TUBERCULOSIS; P38 MAPK; P38 MITOGEN-ACTIVATED PROTEIN KINASE; PERIPHERAL BLOOD MONONUCLEAR CELLS; SECRETED ANTIGENIC TARGET; SPECIFIC EFFECTS; T CELLS; TUBERCULOSIS INFECTION;

ANTIGENS; BLOOD; ENZYME ACTIVITY; INTERFERONS; PHOSPHORYLATION;

CELLS;

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALCIUM ION; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FOXP3;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE SILENCING; HUMAN; HUMAN CELL; INTERFERON PRODUCTION; LYMPHOCYTE PROLIFERATION; MYCOBACTERIUM TUBERCULOSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; TUBERCULOSIS;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL PROLIFERATION; CELLS, CULTURED; ENZYME INHIBITORS; GENE SILENCING; HUMANS; IMIDAZOLES; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-17; LATENT TUBERCULOSIS; MAP KINASE KINASE 4; MYCOBACTERIUM TUBERCULOSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PYRIDINES; T-LYMPHOCYTES;

MYCOBACTERIUM TUBERCULOSIS;

EID: 79959911673     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.234062     Document Type: Article

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