Networked T cell death following macrophage infection by mycobacterium tuberculosis

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Macdonald, Stephen H F ^a   Woodward, Elliott ^a   Coleman, Michelle M ^a   Dorris, Emma R ^a   Nadarajan, Parthiban ^a   Chew, Wui Mei ^a   McLaughlin, Anne Marie ^a   Keane, Joseph ^a  

^a ST JAMES S HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; EARLY SECRETORY ANTIGENIC TARGET 6; FAS ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; BACTERIAL ANTIGEN; FAS PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BACTERIUM CULTURE; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNE RESPONSE; LUNG ALVEOLUS MACROPHAGE; LYMPHOCYTE COUNT; MOLECULAR WEIGHT; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; SUPERNATANT; T LYMPHOCYTE; TUBERCULOSIS; CELL FRACTIONATION; CYTOLOGY; DRUG EFFECT; IMMUNOLOGY; LYMPHOCYTOPENIA; METABOLISM; MICROBIOLOGY; PATHOLOGY; PREVALENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

BACILLI (CLASS); MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS;

ANTIGENS, BACTERIAL; ANTIGENS, CD95; CASPASES; CELL DEATH; CELL LINE, TUMOR; HUMANS; LYMPHOCYTE COUNT; LYMPHOPENIA; MACROPHAGES, ALVEOLAR; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; PREVALENCE; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; T-LYMPHOCYTES; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84861862862     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038488     Document Type: Article

References (45)

1. Davoudi S, Rasoolinegad M, Younesian M, Hajiabdolbaghi M, Soudbakhsh A, et al. (2008) CD4+ cell counts in patients with different clinical manifestations of tuberculosis. Brazilian Journal of Infectious Diseases 12: 483-486.
2. Jones BE, Oo MM, Taikwel EK, Qian D, Kumar A, et al. (1997) CD4 Cell Counts in Human Immunodeficiency Virus-Negative Patients with Tuberculosis. Clinical Infectious Diseases 24: 988-991.
3. Baena A, Porcelli SA, (2009) Evasion and subversion of antigen presentation by Mycobacterium tuberculosis. Tissue Antigens 74: 189-204.
4. Schmolke M, García-Sastre A, (2010) Evasion of innate and adaptive immune responses by influenza A virus. Cellular Microbiology 12: 873-880.
5. Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, et al. (2004) Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages. Cell 119: 753-766.
6. Blanchette J, Jaramillo M, Olivier M, (2003) Signalling events involved in interferon-γ-inducible macrophage nitric oxide generation. Immunology 108: 513-522.
7. Herbst S, Schaible UE, Schneider BE, (2011) Interferon Gamma Activated Macrophages Kill Mycobacteria by Nitric Oxide Induced Apoptosis. PLoS ONE 6: e19105.
8. Pilheu JA, Salvo MCD, Gonzalez J, Rey D, Elias MC, et al. (1997) CD4+ T-lymphocytopenia in severe pulmonary tuberculosis without evidence of human immunodeficiency virus infection. The International Journal of Tuberculosis and Lung Disease 1: 422-426.
9. Hirsch CS, Toossi Z, Othieno C, Johnson JL, Schwander SK, et al. (1999) Depressed T-Cell Interferon-γ Responses in Pulmonary Tuberculosis: Analysis of Underlying Mechanisms and Modulation with Therapy. Journal of Infectious Diseases 180: 2069-2073.
10. Egen JG, Rothfuchs AG, Feng CG, Winter N, Sher A, et al. (2008) Macrophage and T Cell Dynamics during the Development and Disintegration of Mycobacterial Granulomas. Immunity 28: 271-284.
11. Saunders BM, Britton WJ, (2007) Life and death in the granuloma: immunopathology of tuberculosis. Immunol Cell Biol 85: 103-111.
12. Keane J, Remold HG, Kornfeld H, (2000) Virulent Mycobacterium tuberculosis Strains Evade Apoptosis of Infected Alveolar Macrophages. The Journal of Immunology 164: 2016-2020.
13. Mustafa T, Wiker H, Mørkve O, Sviland L, (2008) Differential expression of mycobacterial antigen MPT64, apoptosis and inflammatory markers in multinucleated giant cells and epithelioid cells in granulomas caused by Mycobacterium tuberculosis. Virchows Archiv 452: 449-456.
14. Mustafa T, Mogga SJ, Mfinanga SGM, Mørkve O, Sviland L, (2006) Immunohistochemical analysis of cytokines and apoptosis in tuberculous lymphadenitis. Immunology 117: 454-462.
15. Hirsch CS, Johnson JL, Okwera A, Kanost RA, Wu M, et al. (2005) Mechanisms of Apoptosis of T-Cells in Human Tuberculosis. Journal of Clinical Immunology 25: 353-364.
16. Sharma S, Sharma M, Bose M, (2008) Mycobacterium tuberculosis infection of human monocyte-derived macrophages leads to apoptosis of T cells. Immunol Cell Biol 87: 226-234.
17. Zhong J, Gilbertson B, Cheers C, (2003) Apoptosis of CD4+ and CD8+ T cells during experimental infection with Mycobacterium avium is controlled by Fas/FasL and Bcl-2-sensitive pathways, respectively. Immunol Cell Biol 81: 480-486.
18. Kelly DM, ten Bokum AMC, O'Leary SM, O'Sullivan MP, Keane J, (2008) Bystander Macrophage Apoptosis after Mycobacterium tuberculosis H37Ra Infection. Infect Immun 76: 351-360.
19. Schaible UE, Winau F, Sieling PA, Fischer K, Collins HL, et al. (2003) Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis. Nat Med 9: 1039-1046.
20. Keane J, Balcewicz-Sablinska MK, Remold HG, Chupp GL, Meek BB, et al. (1997) Infection by Mycobacterium tuberculosis promotes human alveolar macrophage apoptosis. Infect Immun 65: 298-304.
21. Ryan RC, O'Sullivan MP, Keane J, (2011) Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells. BMC Microbiol 11: 237.
22. Gilbertson B, Zhong J, Cheers C, (1999) Anergy, IFN-γ Production, and Apoptosis in Terminal Infection of Mice with Mycobacterium avium. The Journal of Immunology 163: 2073-2080.
23. O'Leary S, O'Sullivan MP, Keane J, (2010) IL-10 Blocks Phagosome Maturation in Mycobacterium tuberculosis-infected Human Macrophages. Am J Respir Cell Mol Biol pp. 2010-0319OC.
24. O'Sullivan MP, O'Leary S, Kelly DM, Keane J, (2007) A Caspase-Independent Pathway Mediates Macrophage Cell Death in Response to Mycobacterium tuberculosis Infection. Infect Immun 75: 1984-1993.
25. Derrick SC, Morris SL, (2007) The ESAT6 protein of Mycobacterium tuberculosis induces apoptosis of macrophages by activating caspase expression. Cellular Microbiology 9: 1547-1555.
26. Sanchez A, Espinosa P, Esparza MA, Colon M, Bernal G, et al. (2009) Mycobacterium tuberculosis 38-kDa Lipoprotein is Apoptogenic for Human Monocyte-derived Macrophages. Scandinavian Journal of Immunology 69: 20-28.
27. Wojtas B, Fijalkowska B, Wlodarczyk A, Schollenberger A, Niemialtowski M, et al. (2011) Mannosylated lipoarabinomannan balances apoptosis and inflammatory state in mycobacteria-infected and uninfected bystander macrophages. Microbial Pathogenesis 51: 9-21.
28. Mahon RN, Rojas RE, Fulton SA, Franko JL, Harding CV, et al. (2009) Mycobacterium tuberculosis Cell Wall Glycolipids Directly Inhibit CD4+ T-Cell Activation by Interfering with Proximal T-Cell-Receptor Signaling. Infect Immun 77: 4574-4583.
29. Danelishvili L, Yamazaki Y, Selker J, Bermudez LE, (2010) Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c Proteins Participate in the Suppression of Macrophage Apoptosis. PLoS ONE 5: e10474.
30. Singhal A, Jaiswal A, Arora VK, Prasad HK, (2007) Modulation of Gamma Interferon Receptor 1 by Mycobacterium tuberculosis: a Potential Immune Response Evasive Mechanism. Infect Immun 75: 2500-2510.
31. Master SS, Rampini SK, Davis AS, Keller C, Ehlers S, et al. (2008) Mycobacterium tuberculosis Prevents Inflammasome Activation. Cell Host & Microbe 3: 224-232.
32. Samten B, Wang X, Barnes PF, (2009) Mycobacterium tuberculosis ESX-1 system-secreted protein ESAT-6 but not CFP10 inhibits human T-cell immune responses. Tuberculosis 89: S74-S76.
33. Welsh KJ, Risin SA, Actor JK, Hunter RL, (2010) Immunopathology of Postprimary Tuberculosis: Increased T-Regulatory Cells and DEC-205-Positive Foamy Macrophages in Cavitary Lesions. Clinical and Developmental Immunology 2011.
34. Mellor AL, Munn DH, (2008) Creating immune privilege: active local suppression that benefits friends, but protects foes. Nat Rev Immunol 8: 74-80.
35. Green JA, Elkington PT, Pennington CJ, Roncaroli F, Dholakia S, et al. (2010) Mycobacterium tuberculosis Upregulates Microglial Matrix Metalloproteinase-1 and-3 Expression and Secretion via NF-kappaB and Activator Protein-1-Dependent Monocyte Networks. The Journal of Immunology 184: 6492-6503.
36. Gupta RK, Srivastava BS, Srivastava R, (2010) Comparative expression analysis of rpf-like genes of Mycobacterium tuberculosis H37Rv under different physiological stress and growth conditions. Microbiology 156: 2714-2722.
37. Mariani F, Cappelli G, Riccardi G, Colizzi V, (2000) Mycobacterium tuberculosis H37Rv comparative gene-expression analysis in synthetic medium and human macrophage. Gene 253: 281-291.
38. Mahairas GG, Sabo PJ, Hickey MJ, Singh DC, Stover CK, (1996) Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis. J Bacteriol 178: 1274-1282.
39. Renshaw PS, Lightbody KL, Veverka V, Muskett FW, Kelly G, et al. (2005) Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6. Embo J 24: 2491-2498.
40. Wong KW, Jacobs WR Jr, (2011) Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis. Cell Microbiol 13: 1371-1384.
41. Frigui W, Bottai D, Majlessi L, Monot M, Josselin E, et al. (2008) Control of M.tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP. PLoS Pathog 4: e33.
42. Tripathi P, Tripathi P, Kashyap L, Singh V, (2007) The role of nitric oxide in inflammatory reactions. FEMS Immunology & Medical Microbiology 51: 443-452.
43. Tsukimoto M, Maehata M, Harada H, Ikari A, Takagi K, et al. (2006) P2X7 Receptor-Dependent Cell Death Is Modulated during Murine T Cell Maturation and Mediated by Dual Signaling Pathways. The Journal of Immunology 177: 2842-2850.
44. Placido R, Auricchio G, Falzoni S, Battistini L, Colizzi V, et al. (2006) P2X7 purinergic receptors and extracellular ATP mediate apoptosis of human monocytes/macrophages infected with Mycobacterium tuberculosis reducing the intracellular bacterial viability. Cellular Immunology 244: 10-18.
45. Jendro M, Fingerle F, Deutsch T, Liese A, Köhler L, et al. (2004) Chlamydia trachomatis-infected macrophages induce apoptosis of activated T cells by secretion of tumor necrosis factor-α in vitro. Medical Microbiology and Immunology 193: 45-52.